nasoclear cold oral drops delicious cherry - Chlorpheniramine Maleate (1mg/ml) + Paracetamol (125mg/ml) medicine

Jescold Oral Drops Pineapple: Complete Medicine Guide

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for individual components; combination product evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of face, lips, tongue, or throat
  • Severe skin rash or hives
  • Yellowing of skin or eyes (jaundice)
  • Dark urine or pale stools
  • Severe abdominal pain
  • Persistent vomiting
  • Unusual bleeding or bruising
  • Seizures or convulsions
  • Extreme drowsiness or confusion

If experiencing severe symptoms, call emergency services immediately.

What is nasoclear cold oral drops delicious cherry used for?

This medicine is a combination of chlorpheniramine maleate (an antihistamine) and paracetamol (a pain reliever and fever reducer) in a pineapple-flavoured oral drop form. It is used to treat symptoms of common cold and allergies in children, such as runny nose, sneezing, and fever. It should be used only under medical supervision and not exceed the recommended dose.

  • Generic Name: Chlorpheniramine Maleate (1mg/ml) + Paracetamol (125mg/ml)
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nasoclear cold oral drops delicious cherry के बारे में (Hindi Summary)

उपयोग: यह दवा बच्चों में सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, खुजली, आंखों में पानी आना और बुखार को कम करने के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन मेलिएट और पैरासिटामोल दो सक्रिय तत्व होते हैं। क्लोरफेनिरामाइन एक एंटीहिस्टामिन है जो एलर्जी के लक्षणों को कम करता है, और पैरासिटामोल दर्द और बुखार को कम करता है। यह दवा अनानास के स्वाद वाली ओरल ड्रॉप्स के रूप में उपलब्ध है, जिससे बच्चे इसे आसानी से ले सकते हैं। यह दवा केवल डॉक्टर की सलाह पर ही दी जानी चाहिए, खासकर 2 साल से छोटे बच्चों को।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि और पेट में गड़बड़ी शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, यकृत की क्षति और रक्त विकार शामिल हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करते समय सावधानी बरतें। हमेशा दी गई ड्रॉपर से सही मात्रा में दवा दें। अनुशंसित खुराक से अधिक न दें। बिना डॉक्टर की सलाह के 5 दिन से अधिक इस्तेमाल न करें। 2 साल से छोटे बच्चों को डॉक्टर की सलाह के बिना न दें। इस दवा को शराब के साथ न लें। यदि बच्चे को यकृत या गुर्दे की बीमारी, दमा या कोई अन्य चिकित्सीय स्थिति है तो डॉक्टर को बताएं। दवा को बच्चों की पहुंच से दूर रखें। ठंडी, सूखी जगह पर स्टोर करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 nasoclear cold oral drops delicious cherry Uses & Benefits

[{"condition":"Common cold","description":"Provides symptomatic relief from runny nose, sneezing, and fever associated with the common cold in children.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Helps reduce sneezing, rhinorrhea, and itching of the nose and eyes due to allergies.","evidence":"Well-established"},{"condition":"Fever","description":"Paracetamol component helps lower fever in children.","evidence":"Well-established"},{"condition":"Mild to moderate pain","description":"Paracetamol provides relief from mild to moderate pain such as headache, toothache, or body ache.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold and allergic conditions in children

Also treats: Allergic rhinitis, Fever, Mild to moderate pain

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate (1mg/ml) + Paracetamol (125mg/ml)
Brand Namenasoclear cold oral drops delicious cherry
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Do not refrigerate. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always use the dropper provided to measure the dose accurately; household spoons are not reliable.
2
Shake the bottle well before each use to ensure the medicine is evenly mixed.
3
Administer the drops directly into the child's mouth or mix with a small amount of food or liquid if the child refuses.
4
Do not exceed the recommended dose, as paracetamol overdose can cause serious liver damage.
5
Avoid giving this medicine to children under 2 years without consulting a pediatrician.
6
If symptoms persist beyond 5 days or worsen, consult a doctor.
7
Be aware that this medicine may cause drowsiness; avoid activities requiring alertness in older children.
8
Inform your doctor if the child is taking any other medications, especially those for seizures or blood thinning.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing
This medicine helps reduce sneezing due to allergies or cold.
Likely Use
✅
Fever
Paracetamol component helps lower fever.
Likely Use
✅
Itchy eyes
Antihistamine component helps relieve itching.
Likely Use
❌
Cough
This medicine is not a cough suppressant; consult a doctor for cough.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is well absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract. The oral drops formulation is designed for quick absorption, especially in pediatric patients.
DistributionChlorpheniramine maleate is widely distributed throughout the body, including the central nervous system. Paracetamol is distributed widely into most body tissues, with a volume of distribution of approximately 0.95 L/kg.
Protein BindingChlorpheniramine maleate is approximately 70% bound to plasma proteins. Paracetamol is only minimally bound to plasma proteins (about 10-25%).
MetabolismChlorpheniramine maleate is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2D6, to inactive metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI), which is normally detoxified by glutathione.
Half-LifeThe elimination half-life of chlorpheniramine maleate is approximately 12-15 hours in adults, but may be longer in children and the elderly. The elimination half-life of paracetamol is about 2-3 hours in adults, but may be prolonged in cases of liver damage.
ExcretionChlorpheniramine maleate and its metabolites are excreted primarily in the urine. Paracetamol metabolites are excreted in the urine, with about 90% of the dose excreted within 24 hours.
BioavailabilityChlorpheniramine maleate has a bioavailability of about 25-50% due to first-pass metabolism. Paracetamol has a high bioavailability of about 80-100% after oral administration.
Onset of ActionThe onset of action for chlorpheniramine is about 30-60 minutes after oral administration. Paracetamol begins to reduce fever within 30-60 minutes and provides pain relief within 30-60 minutes.
Peak Plasma TimeChlorpheniramine reaches peak plasma concentrations in about 2-3 hours. Paracetamol reaches peak plasma concentrations in about 0.5-2 hours.
Duration of ActionThe effects of chlorpheniramine last about 4-6 hours, while paracetamol's effects last about 4-6 hours.

How It Works

This medicine contains two active ingredients. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which leads to analgesic and antipyretic effects. The exact mechanism of paracetamol is not fully understood, but it is believed to involve inhibition of cyclooxygenase (COX) enzymes, particularly COX-2, in the brain.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine maleate binds to H1 receptors on effector cells, preventing histamine from binding and triggering allergic symptoms.
2
Central nervous system depression: Chlorpheniramine crosses the blood-brain barrier and blocks H1 receptors in the brain, causing sedation.
3
Prostaglandin synthesis inhibition: Paracetamol inhibits prostaglandin synthesis in the central nervous system, leading to analgesic and antipyretic effects.
4
Hypothalamic action: Paracetamol acts on the hypothalamus to reduce fever by promoting heat loss.

💡 How to Take nasoclear cold oral drops delicious cherry

Strength: Oral drops: Chlorpheniramine Maleate 1 mg/ml + Paracetamol 125 mg/ml

1Shake the bottle well before use.
2Use the dropper provided to measure the exact dose.
3Administer the drops directly into the child's mouth or mix with a small amount of food or liquid.
4Wash the dropper after each use.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThis medicine is primarily intended for pediatric use. For adults, the dosage must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Typically, chlorpheniramine maleate adult dose is 4 mg every 4-6 hours, and paracetamol adult dose is 500-1000 mg every 4-6 hours as needed, not exceeding 4000 mg per day. However, this oral drop formulation is not intended for adults unless specifically prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. The dosage depends on the child's age and weight. Generally, for children 2-6 years, chlorpheniramine maleate dose is 1 mg every 4-6 hours, and paracetamol dose is 10-15 mg/kg every 4-6 hours. Do not exceed 5 doses in 24 hours. Use the dropper provided for accurate measurement.
Elderly DosageElderly patients may be more sensitive to the effects of chlorpheniramine, especially drowsiness and anticholinergic effects. Use with caution. Dose adjustment may be needed based on renal and hepatic function. Consult a doctor.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be needed. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Paracetamol dose should be reduced or avoided in severe liver disease. Consult a doctor.
Maximum Daily DoseFor children 2-6 years: Chlorpheniramine maleate maximum 6 mg per day; Paracetamol maximum 60 mg/kg per day. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect absorption, but may reduce stomach upset.
Alcohol
Avoid
Increases CNS depression and risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nasoclear cold oral drops delicious cherry

✅ Common Side Effects

Drowsiness (Common (10-20%))
Usually resolves with continued use. Avoid driving or operating machinery. Consult doctor if persistent.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid sudden movements. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food or milk. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you notice rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, abdominal pain, or nausea.
Blood disorders (e.g., thrombocytopenia, leukopenia) (Rare (<0.1%))
Consult doctor if you notice unusual bleeding or bruising, fever, or sore throat.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Hallucinations
Seek immediate medical attention.
Irregular heartbeat
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Alcohol Major
Warfarin Major
CNS depressants Moderate
Anticholinergics Moderate
Carbamazepine Moderate
Antacids Minor
Cholestyramine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Alcohol
  • Warfarin

⚡ Moderate Interactions

  • CNS depressants (e.g., benzodiazepines, opioids, sedatives)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Carbamazepine

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase central nervous system depression, leading to excessive drowsiness, dizziness, and impaired coordination. Additionally, alcohol can increase the risk of liver damage from paracetamol, especially with high doses or prolonged use.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, paracetamol, or any component of the formulation","Severe liver disease or severe renal impairment","Children under 2 years of age (unless prescribed by a doctor)","Patients taking MAOIs or within 14 days of stopping MAOIs","Narrow-angle glaucoma","Urinary retention","Severe hypertension"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose. High doses of paracetamol can cause serious liver damage.","Avoid alcohol while taking this medicine.","May cause drowsiness. Avoid driving or operating machinery until you know how this medicine affects you.","Use with caution in patients with liver or kidney disease, asthma, or prostatic hypertrophy.","Do not use for more than 5 days without consulting a doctor.","Keep out of reach of children.","If symptoms persist or worsen, consult a doctor.","Do not use if the solution is discoloured or contains particles."]

🤱 Lactation Safety

Chlorpheniramine and paracetamol are excreted in breast milk. Use with caution during breastfeeding. Consult a doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol, and anticholinergic toxicity due to chlorpheniramine. Symptoms of overdose include nausea, vomiting, abdominal pain, confusion, drowsiness, tachycardia, and seizures. If overdose is suspected, seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Always use the dropper provided to measure the dose accurately. Do not exceed the recommended dose. Avoid using this medicine for more than 5 days without consulting a doctor. Do not give this medicine to children under 2 years of age unless prescribed by a doctor. Avoid alcohol and other central nervous system depressants while taking this medicine. Inform your doctor if the child has liver or kidney disease, asthma, or any other medical condition. Do not use this medicine if the child is allergic to chlorpheniramine, paracetamol, or any other ingredients. Keep out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not use if the solution is discoloured or contains particles.

👴 Special Considerations for Elderly

💡 For Patients Above 65

This medicine is primarily for pediatric use. In elderly patients, chlorpheniramine can cause increased drowsiness, confusion, and anticholinergic effects. Paracetamol dose should be adjusted in liver or kidney impairment. Use with caution and consult a doctor.

🤰 Pregnancy Planning (TTC)

This medicine is not intended for use in pregnancy without medical advice. If you are pregnant or planning to become pregnant, consult a doctor before using this medicine. Chlorpheniramine and paracetamol should be used during pregnancy only if clearly needed and under medical supervision.

🏥 Post-Surgery Considerations

Consult a doctor before using this medicine after surgery, as it may interact with anesthetics and other medications. Paracetamol can be used for post-operative pain if approved by the surgeon.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with medications used during dental procedures. Paracetamol can be used for dental pain, but chlorpheniramine may cause dry mouth, which can affect dental health.

💚 Lifestyle Tips for Better Results

🏃
Ensure your child gets plenty of rest to help the body fight off the infection.
🥗
Keep your child well hydrated with water, soups, and juices.
😴
Use a humidifier in the room to ease nasal congestion.
💧
Avoid exposing your child to smoke, dust, or other allergens.
🧘
Practice good hand hygiene to prevent the spread of infections.
🌞
Dress your child in comfortable clothing to help regulate body temperature.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Children should avoid activities that require mental alertness, such as swimming, cycling, or playing on playground equipment, until they know how the medicine affects them. Encourage quiet indoor activities while symptoms persist.

🥗 Diet Recommendations

Offer warm fluids like soup and herbal tea to soothe the throat and loosen mucus.
Include vitamin C-rich fruits like oranges and strawberries to support immunity.
Avoid cold drinks and ice cream, which may worsen throat irritation.
Provide soft, easy-to-swallow foods if the child has a sore throat.
Avoid giving the child heavy, spicy, or oily foods that may upset the stomach.

💼 Impact on Daily Work & Life

For children, this medicine may cause drowsiness, which can affect school performance and daily activities. It is advisable to keep the child at home if they are drowsy or unwell. For adults taking this medicine (though not typically intended), it may impair the ability to drive or operate machinery. Avoid such activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult a doctor if symptoms do not improve within 5 days, if they worsen, or if new symptoms appear. Do not stop abruptly if you have been taking it for a long time without consulting a doctor, as withdrawal effects may occur with chlorpheniramine.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of chlorpheniramine can lead to tolerance, dependence, and anticholinergic side effects. Prolonged use of paracetamol, especially at high doses, can cause liver damage. Regular monitoring of liver function may be required if used for extended periods. Consult a doctor if symptoms persist beyond 5 days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal drops

Can help relieve nasal congestion in children without medication.

Evidence: Well-established
Cool-mist humidifier

Adds moisture to the air, easing breathing and reducing congestion.

Evidence: Well-established
Honey

A teaspoon of honey can help soothe cough and sore throat in children over 1 year.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if the child has a fever, vaccination may be postponed until the fever subsides. Consult a pediatrician for guidance.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label intact. Keep a copy of the prescription with you, especially for international travel. Store the bottle in a cool, dry place, away from direct sunlight. Do not leave it in a hot car. If traveling across time zones, continue with the usual dosing schedule based on the time elapsed since the last dose. Check customs regulations for carrying medications across borders.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 3-year-old child with runny nose and mild fever
The child was given this medicine as prescribed by the pediatrician. Within 30 minutes, the fever started to subside and the runny nose reduced. The child was a bit sleepy but otherwise fine. The parent was advised to give the medicine every 6 hours as needed and to keep the child hydrated.
💡 Lesson: This medicine effectively relieves cold symptoms in children, but drowsiness is a common side effect. Always follow the prescribed dose and monitor the child.
👤 A 5-year-old with allergic rhinitis
The child had persistent sneezing and itchy eyes during pollen season. The doctor prescribed this medicine. After a few doses, the sneezing and itching significantly reduced. The parent was advised to avoid allergens and to use the medicine only when symptoms flare up.
💡 Lesson: This medicine can be effective for allergic rhinitis in children, but it should be used judiciously and not as a long-term solution without medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts to work within 30-60 minutes after administration. Fever and pain relief may be noticed within 30 minutes, while antihistamine effects on runny nose and sneezing may take up to an hour.

Q: Can I give this medicine to my child with other medications?

A: Always consult a doctor before giving this medicine with other medications, as it can interact with certain drugs, especially CNS depressants, MAOIs, and warfarin. Do not give multiple cold medicines without medical advice.

Q: Is this medicine safe for infants?

A: This medicine is not recommended for infants under 2 years of age unless prescribed by a pediatrician. The dosage for infants must be determined by a doctor based on weight and medical condition.

Q: What should I do if my child vomits after taking this medicine?

A: If your child vomits within 15-30 minutes of taking the medicine, do not repeat the dose unless advised by a doctor. If vomiting occurs later, it is likely that the medicine has been absorbed. Consult a doctor if you are unsure.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my child's kidney function?
  • Can my child go to school after taking this medicine?
  • Does it interact with other cold medicines?
  • What if I miss a dose?
  • Can I give this medicine with food?

🔄 Substitutes for nasoclear cold oral drops delicious cherry

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any type of cold.
    Fact: This medicine is for symptomatic relief of common cold and allergies. It does not cure the underlying infection. Consult a doctor for proper diagnosis.
  • Myth: More medicine will make my child feel better faster.
    Fact: Exceeding the recommended dose can cause serious side effects, including liver damage. Always follow the prescribed dose.
  • Myth: This medicine is safe for all ages.
    Fact: This medicine is not recommended for children under 2 years of age without medical advice. Always consult a pediatrician.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine maleate + Paracetamol oral drops

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","form":"Oral drops","strength":"Chlorpheniramine 1 mg/ml + Paracetamol 125 mg/ml","route":"Oral","use":"Pediatric cold and allergy symptoms"},{"medicine":"Chlorpheniramine + Paracetamol syrup","form":"Syrup","strength":"Varies","route":"Oral","use":"Pediatric cold and allergy symptoms"}]

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