nandrosar 25mg injection - Information coming soon medicine

Nandrosar 25mg Injection: Comprehensive Medicine Guide

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Information coming soon
🏭 Generic 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category This medicine is contraindicated in pregnancy. It has been associated with fetal harm, including virilization of the female fetus. Women who are pregnant or may become pregnant should not use this medicine. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited evidence for most uses; not a first-line therapy.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Chest pain or shortness of breath
  • Severe abdominal pain with nausea or vomiting
  • Yellowing of skin or eyes (jaundice)
  • Dark urine or pale stools
  • Sudden swelling of face, lips, or throat
  • Decreased urine output
  • Severe headache with visual changes
  • Prolonged and painful erection (priapism)

If experiencing severe symptoms, call emergency services immediately.

What is nandrosar 25mg injection used for?

This medicine is an anabolic steroid injection used to treat anemia of chronic kidney disease and osteoporosis in postmenopausal women. It works by stimulating red blood cell production and increasing bone density. It must be given by a healthcare professional and is not for general use.

  • Generic Name: Information coming soon
  • Manufacturer: Multiple manufacturers
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nandrosar 25mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा नैंड्रोलोन फेनिलप्रोपियोनेट 25 मिलीग्राम इंजेक्शन है, जिसका उपयोग कुछ विशेष चिकित्सीय स्थितियों में किया जाता है। इसका मुख्य उपयोग क्रोनिक किडनी रोग से जुड़े एनीमिया और पोस्टमेनोपॉज़ल महिलाओं में ऑस्टियोपोरोसिस के इलाज में किया जाता है। यह दवा लाल रक्त कोशिकाओं के उत्पादन को बढ़ाकर और हड्डियों के घनत्व में सुधार करके काम करती है। यह दवा केवल एक योग्य चिकित्सक की देखरेख में ही दी जानी चाहिए और इसे स्वयं नहीं लगाना चाहिए। यह दवा बॉडीबिल्डिंग या एथलेटिक प्रदर्शन बढ़ाने के लिए नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा या सूजन, शरीर में पानी का जमाव, मुँहासे और कामेच्छा में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में हृदय संबंधी घटनाएँ जैसे उच्च रक्तचाप, थ्रोम्बोएम्बोलिज्म, यकृत की समस्याएँ जैसे पीलिया और लीवर ट्यूमर, तथा हार्मोनल असंतुलन जैसे स्तन वृद्धि और अंडकोष का सिकुड़ना शामिल हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल एक स्वास्थ्य पेशेवर द्वारा इंट्रामस्क्युलर इंजेक्शन के रूप में दी जानी चाहिए। इसे स्वयं न लगाएं। इस दवा का उपयोग करते समय नियमित रूप से लीवर फंक्शन, लिपिड प्रोफाइल, हेमेटोक्रिट और पुरुषों में प्रोस्टेट-स्पेसिफिक एंटीजन (PSA) की निगरानी आवश्यक है। शराब का सेवन न करें क्योंकि इससे लीवर की विषाक्तता बढ़ सकती है। यदि आपको हृदय रोग, यकृत रोग, गुर्दा रोग या रक्त के थक्के बनने की समस्या है तो अपने डॉक्टर को बताएं। यह दवा गर्भावस्था और स्तनपान के दौरान contraindicated है।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 nandrosar 25mg injection Uses & Benefits

[{"condition":"Anemia of chronic kidney disease","description":"This medicine may be used to stimulate erythropoiesis in patients with anemia associated with chronic kidney disease, particularly when other treatments are ineffective or not tolerated.","evidence":"Limited evidence"},{"condition":"Osteoporosis in postmenopausal women","description":"This medicine may be prescribed to increase bone mineral density in postmenopausal women with osteoporosis, although it is not a first-line therapy.","evidence":"Limited evidence"},{"condition":"Aplastic anemia","description":"In some cases, this medicine may be used as adjunctive therapy for aplastic anemia to stimulate red blood cell production.","evidence":"Limited evidence"}]

Off-label uses: [{"condition":"Cachexia associated with chronic illness","description":"Sometimes used off-label to promote weight gain and muscle mass in patients with cachexia due to cancer or HIV/AIDS.","evidence":"Limited"},{"condition":"Hereditary angioedema","description":"Rarely used off-label to prevent attacks of hereditary angioedema by increasing C1 esterase inhibitor levels.","evidence":"Limited"}]

Primary treatment for: Anemia of chronic kidney disease

Also treats: Osteoporosis in postmenopausal women, Aplastic anemia

📋 Drug Information

Generic Name(s)Information coming soon
Brand Namenandrosar 25mg injection
ManufacturerMultiple manufacturers
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassAnabolic steroid
Route of AdministrationParenteral (intramuscular injection)
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and freezing. Keep in the original container until ready to use.
Shelf LifeThe shelf life of this medicine is typically 24 months from the date of manufacture. Refer to the product label for the exact expiration date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only under the supervision of a qualified clinician.
2
Monitor liver function tests, lipid profile, and hematocrit regularly during therapy.
3
Assess prostate-specific antigen (PSA) levels in male patients before and during treatment.
4
Avoid concurrent use with hepatotoxic drugs to minimize liver injury risk.
5
Counsel patients to report any signs of fluid retention, jaundice, or cardiovascular symptoms immediately.
6
Do not use this medicine for athletic performance enhancement or bodybuilding.
7
Consider alternative therapies in elderly patients due to increased cardiovascular risk.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic anemia
This medicine may be prescribed for anemia of chronic kidney disease.
Likely Use
✅
Bone pain or fractures
This medicine may be used for osteoporosis in postmenopausal women.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Muscle weakness
This medicine is not indicated for general muscle weakness.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered via intramuscular injection and is absorbed slowly from the injection site. The esterified form is hydrolyzed to release the active nandrolone, which then enters the systemic circulation. The absorption rate is influenced by the oil-based vehicle and the injection site.
DistributionNandrolone is highly bound to plasma proteins and distributes widely into body tissues, with a particular affinity for androgen-responsive tissues such as muscle, bone, and reproductive organs. It crosses the placenta and is excreted in breast milk.
Protein BindingNandrolone is approximately 80% bound to plasma proteins, primarily to sex hormone-binding globulin (SHBG) and albumin.
MetabolismNandrolone is extensively metabolized in the liver via reduction and conjugation reactions. The primary metabolites include 19-norandrosterone and 19-noretiocholanolone, which are excreted in urine.
Half-LifeThe elimination half-life of nandrolone phenylpropionate is approximately 4 to 5 days after intramuscular injection.
ExcretionNandrolone and its metabolites are primarily excreted in the urine, with a small amount excreted in feces.
BioavailabilityBioavailability following intramuscular injection is high, as the drug bypasses first-pass metabolism. The exact bioavailability is not well established but is considered to be near 100%.
Onset of ActionThe onset of action for this medicine is gradual, with effects on erythropoiesis typically observed within 2 to 3 weeks of therapy. Anabolic effects on muscle and bone may take several weeks to become apparent.
Peak Plasma TimePeak plasma concentrations of nandrolone are typically reached within 24 to 48 hours after intramuscular injection of the phenylpropionate ester.
Duration of ActionThe duration of action of this medicine is approximately 1 to 2 weeks after a single intramuscular injection, depending on the dose and individual patient factors.

How It Works

This medicine is an anabolic-androgenic steroid that binds to androgen receptors in the cytoplasm of target cells. The receptor-ligand complex then translocates to the nucleus and interacts with specific DNA sequences to modulate gene transcription. This leads to increased protein synthesis, nitrogen retention, and erythropoietin production, which collectively promote anabolic effects in muscle and bone and stimulate red blood cell production.

Mechanism Steps

1
Binding to androgen receptor: This medicine diffuses into target cells and binds to the cytoplasmic androgen receptor.
2
Receptor translocation: The drug-receptor complex undergoes a conformational change and translocates into the nucleus.
3
Gene transcription modulation: The complex binds to hormone response elements on DNA, altering the transcription of specific genes.
4
Protein synthesis and erythropoiesis: This leads to increased protein synthesis, nitrogen retention, and stimulation of erythropoietin production, resulting in anabolic and hematopoietic effects.

💡 How to Take nandrosar 25mg injection

Strength: Nandrolone phenylpropionate 25 mg per mL injection (immediate release)

1This medicine is given by a healthcare professional as an intramuscular injection.
2The injection is typically administered into the gluteal muscle.
3Do not self-administer this medicine.
4Follow your healthcare provider's instructions regarding dose and frequency.
5Attend regular follow-up appointments for monitoring.

Dosage Information

Adult DosageThe dosage of this medicine must be individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and clinical response. For anemia of chronic kidney disease, a typical adult dose may range from 25 mg to 100 mg intramuscularly every 1 to 4 weeks. For osteoporosis, doses of 25 mg to 50 mg every 3 to 4 weeks have been used. Do not self-administer; this medicine must be given by a healthcare professional.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the cardiovascular and endocrine side effects of this medicine. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function.
Renal ImpairmentNo specific dose adjustment is provided in the available information. Use with caution in patients with renal impairment and monitor for fluid retention.
Hepatic ImpairmentThis medicine is contraindicated in severe liver disease. In patients with mild to moderate hepatic impairment, use with caution and monitor liver function tests regularly. Dose adjustment may be necessary.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Dosing is typically intermittent (e.g., weekly or every few weeks) rather than daily. Follow your clinician's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Contact your healthcare provider for instructions.
💡 Do not self-administer a missed dose.
📌 More than half the dosing interval has passed
→ Skip the missed dose and resume your regular schedule.
💡 Do not double dose to catch up.

⚠️ Side Effects of nandrosar 25mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the injection site and avoid rubbing. Consult your doctor if pain persists or worsens.
Fluid retention (Common (5-10%))
Reduce salt intake and monitor for swelling in ankles or hands. Inform your doctor if weight gain or swelling occurs.
Acne (Common (5-10%))
Keep skin clean and avoid oily products. Consult a dermatologist if acne becomes severe.
Changes in libido (Common (5-10%))
Discuss with your doctor if this becomes bothersome. Dose adjustment may be necessary.

🚨 Serious Side Effects

Cardiovascular events (e.g., hypertension, thromboembolism) (Uncommon (0.1-1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or swelling in legs.
Hepatic dysfunction (e.g., peliosis hepatis, liver tumors) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor immediately.
Endocrine effects (e.g., testicular atrophy, gynecomastia) (Uncommon (0.1-1%))
Consult your doctor if you notice breast enlargement, testicular shrinkage, or impotence.
Anaphylaxis (Rare (<0.1%))
Seek emergency medical help if you experience rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Cholestatic jaundice
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or pale stools.
Priapism
Seek emergency medical care if you have a prolonged and painful erection.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Insulin Moderate
Corticosteroids Moderate
Anticoagulants (e.g., heparin) Moderate
Cyclosporine Moderate
Tacrolimus Moderate
Lithium Minor
Antihypertensives Moderate
Probenecid Minor

🚨 Major Interactions

  • Warfarin
  • Hepatotoxic drugs (e.g., methotrexate, acetaminophen)

⚡ Moderate Interactions

  • Insulin and oral hypoglycemics
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol should be avoided while using this medicine because both alcohol and nandrolone can stress the liver, increasing the risk of hepatotoxicity. Additionally, alcohol may exacerbate fluid retention and cardiovascular effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to nandrolone or any component of the formulation","Male breast cancer or prostate cancer","Pregnancy or breastfeeding","Severe liver disease","Nephrotic syndrome","Hypercalcemia"]

⚠️ Warnings & Precautions

["This medicine should only be used under the supervision of a qualified clinician.","Do not use for athletic performance enhancement or bodybuilding.","May cause fluid retention; use with caution in patients with heart failure or hypertension.","May impair glucose tolerance; monitor blood glucose in diabetic patients.","May suppress clotting factors; monitor coagulation in patients on anticoagulants.","Prolonged use may lead to dependence and withdrawal symptoms.","Women may experience virilization; discontinue if signs occur.","Use with caution in elderly patients due to increased risk of prostate hypertrophy and cardiovascular events."]

🤱 Lactation Safety

This medicine is excreted in breast milk and may cause serious adverse effects in a nursing infant. Breastfeeding is not recommended while using this medicine.

💊 Overdose Management

Overdose with this medicine is unlikely due to its intramuscular route and medical supervision. In case of accidental overdose, treatment should be symptomatic and supportive. There is no specific antidote. Monitor for signs of fluid retention, cardiovascular events, and liver toxicity. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose of this medicine, contact your healthcare provider for instructions. Do not double the dose to catch up. Your doctor will determine the best course of action based on your dosing schedule.

Additional Safety Advice

General Safety

This medicine must only be administered by a healthcare professional via intramuscular injection. Do not self-administer. Regular monitoring of liver function, lipid profile, hematocrit, and prostate-specific antigen (in males) is essential during therapy. Avoid alcohol consumption as it may increase liver toxicity. Inform your doctor if you have a history of heart disease, liver disease, kidney disease, or blood clotting disorders. This medicine is contraindicated in pregnancy and breastfeeding. Do not share this medicine with others. Keep out of reach of children. Follow your doctor's instructions exactly regarding dose and frequency.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the cardiovascular and endocrine side effects of this medicine. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated in pregnancy and should not be used by women who are planning to become pregnant. It may cause fetal harm, including virilization of the female fetus. Discuss alternative treatments with your healthcare provider if you are planning pregnancy.

🏥 Post-Surgery Considerations

This medicine may increase the risk of thromboembolism after surgery. Use with caution in the postoperative period and monitor for signs of blood clots. Consult your surgeon and healthcare provider before using this medicine after surgery.

🦷 Dental Procedures

No specific considerations are established from the available information. Inform your dentist about this medicine before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Engage in regular low-impact exercise like swimming or walking.
😴
Practice good posture to support bone health.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep to support overall health.
🌞
Avoid smoking and excessive alcohol consumption.

🏋️ Exercise Considerations

While using this medicine, you may experience fluid retention and cardiovascular effects. Avoid strenuous exercise if you have heart or kidney problems. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed food intake.
Stay well hydrated.
Limit salt intake to manage fluid retention.
Ensure adequate calcium and vitamin D for bone health.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fluid retention, which could affect your ability to drive or operate machinery. Avoid driving if you feel unwell. Discuss any work-related concerns with your healthcare provider.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your healthcare provider. If you experience serious side effects such as jaundice, chest pain, or severe allergic reactions, seek immediate medical attention and follow your doctor's advice regarding discontinuation.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to liver toxicity, including peliosis hepatis and liver tumors, cardiovascular events such as hypertension and thromboembolism, and endocrine disturbances like testicular atrophy and gynecomastia. Regular monitoring of liver function, lipid profile, hematocrit, and prostate-specific antigen (in males) is essential. The risk of dependence and withdrawal symptoms also increases with prolonged use. Therapy should be reviewed periodically by a qualified clinician.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Erythropoiesis-stimulating agents (ESAs)

Can be used to treat anemia of chronic kidney disease.

Evidence: Well-established
Bisphosphonates

First-line therapy for osteoporosis in postmenopausal women.

Evidence: Well-established
Physical therapy

Can complement medicine for chronic pain and bone health.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established from the available information. Consult your healthcare provider for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Protect from freezing

❌ DON'T

Do not freeze

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. This medicine is a controlled substance in many countries, so check local regulations before travel. Store it at room temperature and protect it from light and freezing. If you need to adjust your dosing schedule due to time zone changes, consult your healthcare provider beforehand. Always carry enough supply for your trip and keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old woman with postmenopausal osteoporosis
She was prescribed this medicine by her rheumatologist after other treatments failed to improve her bone density. She received intramuscular injections every 4 weeks. After 6 months, her bone mineral density showed improvement, and she experienced no serious side effects. She emphasized the importance of regular monitoring and following the prescribed schedule.
💡 Lesson: Consistent administration and regular monitoring can lead to improved outcomes with this medicine.
👤 A 45-year-old man with anemia of chronic kidney disease
He received this medicine as part of his treatment for anemia. His hemoglobin levels gradually increased over 3 months, reducing his need for blood transfusions. He experienced mild fluid retention, which was managed with dietary salt restriction. He stressed the importance of reporting side effects to his doctor promptly.
💡 Lesson: This medicine can effectively stimulate red blood cell production in chronic kidney disease, but side effects require careful management.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Effects on red blood cell production may be seen within 2 to 3 weeks, while anabolic effects on muscle and bone may take several weeks to become noticeable.

Q: Is this medicine safe for long-term use?

A: Long-term use requires regular monitoring due to risks of liver toxicity, cardiovascular events, and endocrine disturbances. Your doctor will determine the appropriate duration of therapy.

Q: Can I self-administer this injection?

A: No, this medicine must only be administered by a healthcare professional via intramuscular injection.

Q: What should I do if I experience side effects?

A: Report any side effects to your healthcare provider promptly. Seek immediate medical attention for serious symptoms like chest pain, jaundice, or difficulty breathing.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine is safe for bodybuilding.
    Fact: This medicine is a prescription anabolic steroid with serious risks and is not approved for bodybuilding or athletic performance enhancement.
  • Myth: This medicine can be self-administered.
    Fact: This medicine must only be administered by a healthcare professional via intramuscular injection.
  • Myth: This medicine has no side effects.
    Fact: This medicine can cause serious side effects including liver toxicity, cardiovascular events, and endocrine disturbances.

📊 Comparison with Similar Medicines

[{"medicine":"Nandrolone phenylpropionate","class":"Anabolic steroid","half_life":"4-5 days","route":"Intramuscular"},{"medicine":"Nandrolone decanoate","class":"Anabolic steroid","half_life":"6-12 days","route":"Intramuscular"},{"medicine":"Testosterone enanthate","class":"Anabolic steroid","half_life":"4-5 days","route":"Intramuscular"}]

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