Nafodil 50 Tablet (naftopidil 50 Mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Prolonged painful erection lasting more than 4 hours
- Swelling of face, lips, tongue, or throat
- Difficulty breathing
- Chest pain or irregular heartbeat
- Yellowing of skin or eyes
- Decreased urine output
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is naftomax 50 tablet used for?
Naftopidil is an alpha-1 blocker used to treat urinary symptoms of benign prostatic hyperplasia (BPH). It relaxes prostate and bladder neck muscles to improve urine flow. The usual dose is 50 mg once daily, which may be increased to 100 mg. It can cause dizziness and low blood pressure, so rise slowly and avoid alcohol.
- Generic Name: Naftopidil (50mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 naftomax 50 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नैफ्टोपिडिल नामक सक्रिय तत्व से बनी है, जिसका उपयोग बेनाइन प्रोस्टेटिक हाइपरप्लासिया (बीपीएच) के लक्षणों के इलाज के लिए किया जाता है। बीपीएच में प्रोस्टेट ग्रंथि बढ़ जाती है, जिससे पेशाब करने में कठिनाई, बार-बार पेशाब आना, और पेशाब की धारा कमजोर होना जैसी समस्याएं होती हैं। यह दवा प्रोस्टेट और मूत्राशय की गर्दन की मांसपेशियों को ढीला करके पेशाब की धारा को बेहतर बनाती है और लक्षणों को कम करती है। यह दवा बीपीएच का इलाज नहीं है, लेकिन लक्षणों से राहत देती है। इसका सेवन आमतौर पर दिन में एक बार किया जाता है, और खुराक डॉक्टर द्वारा तय की जाती है। महिलाओं और बच्चों के लिए यह दवा नहीं है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और नाक बंद होना शामिल हैं। कुछ लोगों में खड़े होने पर रक्तचाप कम हो सकता है, जिससे चक्कर आना या बेहोशी हो सकती है। दुर्लभ मामलों में धड़कन तेज होना, मतली या टखनों में सूजन हो सकती है। गंभीर दुष्प्रभाव बहुत कम होते हैं, लेकिन अगर आपको लंबे समय तक दर्दनाक इरेक्शन, गंभीर चक्कर, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें और बिना सलाह के बंद न करें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। बैठने या लेटने की स्थिति से धीरे-धीरे उठें ताकि चक्कर न आएं। इस दवा के साथ शराब न लें, क्योंकि इससे रक्तचाप कम हो सकता है। अगर आपको मोतियाबिंद की सर्जरी करानी है, तो अपने नेत्र रोग विशेषज्ञ को इस दवा के बारे में बताएं।
💊 naftomax 50 tablet Uses & Benefits
[{"condition":"Benign prostatic hyperplasia (BPH)","description":"Relieves urinary symptoms such as weak stream, frequency, urgency, and nocturia by relaxing prostatic smooth muscle.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Chronic prostatitis/chronic pelvic pain syndrome","description":"Sometimes used off-label to alleviate pelvic pain and urinary symptoms, but evidence is limited.","evidence":"Limited"},{"condition":"Ureteral stones","description":"May be used off-label to facilitate passage of distal ureteral stones by relaxing ureteral smooth muscle, but not standard.","evidence":"Limited"}]
Primary treatment for: Benign prostatic hyperplasia (BPH)
Also treats: Chronic prostatitis/chronic pelvic pain syndrome (off-label), Ureteral stones (off-label)
📋 Drug Information
| Generic Name(s) | Naftopidil (50mg) |
| Brand Name | naftomax 50 tablet |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Uroselective adrenergic receptor(α1a) antagonist |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Naftopidil selectively blocks alpha-1 adrenergic receptors, with a higher affinity for the alpha-1D subtype that is predominant in the prostate and bladder neck. By antagonizing these receptors, it reduces smooth muscle tone in the prostate and bladder neck, thereby decreasing dynamic obstruction and improving urine flow. It also may have some effect on alpha-1A receptors, but its selectivity for alpha-1D may contribute to fewer blood pressure effects compared to non-selective alpha blockers.
Mechanism Steps
💡 How to Take naftomax 50 tablet
Strength: Tablet, 50 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 50 mg taken orally once daily, preferably at bedtime. The dose may be increased to 100 mg once daily based on individual response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of naftopidil, particularly hypotension and dizziness. Start with a low dose and titrate slowly. Monitor blood pressure regularly. |
| Renal Impairment | No specific dose adjustment is provided in the literature for renal impairment. Use with caution in patients with severe renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is typically required. In severe hepatic impairment, naftopidil should be used with caution or avoided. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | 100 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of naftomax 50 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Prazosin | Major | |
| Terazosin | Major | |
| Doxazosin | Major | |
| Fluoxetine | Moderate | |
| Paroxetine | Moderate | |
| Ketoconazole | Moderate | |
| Rifampin | Moderate | |
| Amlodipine | Moderate |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)
- Other alpha-blockers (e.g., prazosin, terazosin, doxazosin)
- Antihypertensives (e.g., ACE inhibitors, ARBs, beta-blockers, calcium channel blockers)
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of naftopidil, increasing the risk of dizziness, lightheadedness, and fainting. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to naftopidil or any component of the formulation","History of orthostatic hypotension","Severe hepatic impairment","Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)","Women and children"]
⚠️ Warnings & Precautions
["May cause dizziness and orthostatic hypotension; advise patients to rise slowly.","Avoid driving or operating machinery until effects are known.","Use with caution in patients with cardiovascular disease.","Inform ophthalmologist before cataract surgery due to risk of intraoperative floppy iris syndrome (IFIS).","Avoid alcohol consumption.","Use with caution in patients with hepatic or renal impairment.","Not for use in women or children."]
🤱 Lactation Safety
Not applicable. This medicine is not indicated for use in women.
💊 Overdose Management
Overdose may cause severe hypotension, dizziness, and fainting. If overdose is suspected, seek immediate medical attention. Treatment is supportive, including maintenance of blood pressure and heart rate. Gastric lavage may be considered if ingestion is recent. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause dizziness. Rise slowly from a sitting or lying position to prevent dizziness or fainting. Avoid alcohol while taking this medicine, as it can increase the risk of low blood pressure. Inform your doctor if you are taking any other medications, especially for high blood pressure or erectile dysfunction. If you are scheduled for eye surgery (cataract), tell your ophthalmologist that you are taking this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to orthostatic hypotension and dizziness. Start with a low dose and monitor blood pressure regularly. Falls risk should be assessed.
🤰 Pregnancy Planning (TTC)
Not applicable. This medicine is not indicated for women.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with anesthetic agents and cause hypotension during surgery. It may need to be temporarily stopped before surgery as advised by your doctor.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, especially if you are undergoing procedures that may cause bleeding or require anesthesia. It may cause dry mouth, so maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting immediately after starting this medicine, as it may increase the risk of dizziness and low blood pressure. Gradually resume activities as tolerated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. Most people can continue their normal work activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe for managing BPH symptoms. However, regular follow-up with your doctor is recommended to monitor blood pressure, urinary symptoms, and any potential side effects. It does not cure BPH, so symptoms may return if the medicine is stopped. Periodic assessment of prostate health is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Weight loss, fluid management, and avoiding bladder irritants can help reduce BPH symptoms.
Evidence: Well-establishedTamsulosin, silodosin, alfuzosin, etc., may be alternatives with different side effect profiles.
Evidence: Well-establishedFinasteride or dutasteride can shrink the prostate over time but take months to work.
Evidence: Well-establishedTURP or minimally invasive procedures for severe BPH not responding to medication.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. Store at room temperature and avoid direct sunlight. If crossing time zones, continue taking your dose at the same local time as much as possible. Consult your doctor if you need to adjust the timing. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start noticing improvement in urinary symptoms within a few days, but it may take 2-4 weeks for full effect.
A: Yes, it can be taken with or without food. Taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine can cause dizziness. Avoid driving or operating machinery until you know how it affects you.
A: No, taking this medicine with sildenafil or similar drugs can cause a dangerous drop in blood pressure. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for naftomax 50 tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Naftopidil can cure prostate enlargement.
Fact: Naftopidil only relieves symptoms; it does not shrink the prostate or cure BPH. - Myth: Naftopidil works immediately.
Fact: It may take several days to weeks for full symptom relief. - Myth: Naftopidil is safe to take with any blood pressure medicine.
Fact: It can interact with antihypertensives and cause low blood pressure; consult your doctor. - Myth: Naftopidil is for women with urinary problems.
Fact: Naftopidil is not indicated for women; it is for men with BPH.
🔄 Alternative Options
Generic Alternatives
- Naftopidil 50 mg tablet
Brand Alternatives
- Nafodil 50 Tablet