BTR D Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or persistent indigestion
- Chest pain, shortness of breath, or difficulty breathing
- Sudden swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes, dark urine
- Decreased urine output or swelling in legs
- Severe headache with visual disturbances
If experiencing severe symptoms, call emergency services immediately.
What is n rilex plus tablet used for?
This medicine is a combination of Bromelain 90 mg and Diclofenac 50 mg used to relieve pain and inflammation in conditions like arthritis and musculoskeletal injuries. It works by reducing prostaglandins and swelling. Take it with food and avoid alcohol.
- Generic Name: Bromelain (90mg) + Diclofenac (50mg)
- Manufacturer: Little Greave Pharmaceutical Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 n rilex plus tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोमेलेन 90 मिलीग्राम और डाइक्लोफेनाक 50 मिलीग्राम का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह गठिया, मांसपेशियों की चोट, और सर्जरी के बाद की सूजन में प्रभावी है। इसे भोजन के साथ लें और शराब से बचें।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट दर्द, जलन, मतली, सिरदर्द, चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, और हृदय संबंधी घटनाएं हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे हमेशा भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ लेने से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।
💊 n rilex plus tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness, improving mobility in conditions like knee or hip osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps control inflammation and pain in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Used for sprains, strains, and sports injuries to reduce pain and swelling.","evidence":"Well-established"},{"condition":"Post-operative inflammation","description":"May be prescribed after surgery to reduce swelling and pain.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated inflammation.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Sinusitis","description":"Bromelain component may help reduce sinus inflammation and congestion.","evidence":"Limited"},{"condition":"Post-surgical swelling","description":"Sometimes used off-label to reduce edema after minor surgical procedures.","evidence":"Limited"}]
Primary treatment for: Inflammatory pain conditions
Also treats: Osteoarthritis, Rheumatoid arthritis, Musculoskeletal injuries, Post-operative inflammation
📋 Drug Information
| Generic Name(s) | Bromelain (90mg) + Diclofenac (50mg) |
| Brand Name | n rilex plus tablet |
| Manufacturer | Little Greave Pharmaceutical Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Diclofenac inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis and thereby decreasing pain, fever, and inflammation. Bromelain, a proteolytic enzyme, modulates inflammatory mediators, reduces edema, and may enhance tissue repair. Together, they provide symptomatic relief in inflammatory conditions.
Mechanism Steps
💡 How to Take n rilex plus tablet
Strength: Each tablet contains Bromelain 90 mg and Diclofenac 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to two times daily, preferably with food. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function. Do not exceed the recommended dose. For acute conditions, short-term use is advised. For chronic conditions, periodic review is necessary. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are at higher risk of gastrointestinal, kidney, and cardiovascular side effects. Use the lowest effective dose for the shortest duration. Monitor kidney function and for signs of bleeding. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction or avoidance may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be required. Monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 tablets (180 mg bromelain + 100 mg diclofenac). Do not exceed this without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of n rilex plus tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| SSRIs | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- SSRIs
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of stomach bleeding, ulcers, and liver damage. It may also enhance the central nervous system effects like dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or gastrointestinal bleeding","Severe kidney impairment","Severe liver impairment","Heart failure (severe)","Allergy to diclofenac, bromelain, or any NSAID","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft surgery (peri-operative period)"]
⚠️ Warnings & Precautions
["Take with food to minimize stomach upset.","Avoid alcohol and other NSAIDs.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of bleeding, especially if on anticoagulants.","Do not use for prolonged periods without medical supervision.","Inform your doctor if you have a history of heart, kidney, or liver disease.","May cause dizziness; avoid driving until you know how it affects you.","Bromelain may increase the risk of bleeding in patients with bleeding disorders."]
🤱 Lactation Safety
Diclofenac is excreted in breast milk in small amounts. Bromelain safety during lactation is not well established. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe stomach pain, vomiting, bleeding, drowsiness, and kidney failure. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be given if within 1-2 hours of ingestion. Monitor vital signs and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not take other NSAIDs or blood thinners without consulting your doctor. Inform your doctor if you have a history of ulcers, kidney or liver disease, high blood pressure, or heart problems. If you are pregnant or breastfeeding, consult your doctor before use. Do not drive or operate heavy machinery if you feel dizzy. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal, kidney, and cardiovascular side effects. Use the lowest effective dose for the shortest duration. Monitor kidney function and for signs of bleeding.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs like diclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to reduce pain and swelling. Follow your surgeon's instructions carefully. Inform your surgeon about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise temporary discontinuation.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid high-impact exercises that may worsen joint pain. Consult your physiotherapist for safe exercises. Stop exercise if you experience increased pain or swelling.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly impact daily activities if taken as prescribed.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience severe side effects such as stomach bleeding, allergic reactions, or kidney problems. Do not stop abruptly if you are on long-term therapy without consulting your doctor. For short-term use, stop as advised by your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal ulcers, bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is advised. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay provide local pain relief with fewer systemic side effects.
Evidence: Well-establishedMay help reduce pain in some patients.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your doctor about this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat or moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Declare it to customs if required. Keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30-60 minutes after taking the tablet. Anti-inflammatory effects may take a few hours to days.
A: It is best taken with food or milk to reduce stomach irritation.
A: Do not take with other NSAIDs without consulting your doctor, as it increases the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for n rilex plus tablet
View AllAlternative brands with exact same active ingredient:
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brutide-d tabletCanvarzys Healthcare Ltd ₹135.94 3.3% CHEAPER
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thioxib forte tabletAlna Biotech Pvt Ltd ₹135.94 3.3% CHEAPER
-
everheal-d tabletAlcott Healthcare Pvt Ltd ₹136.88 2.6% CHEAPER
-
kinetozyme-d tabletSystopic Laboratories Pvt Ltd ₹139.69 0.6% CHEAPER
-
cumbak tabletAvis Lifecare Pvt Ltd ₹144.38 2.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term without any risk.
Fact: Long-term use of NSAIDs like diclofenac can cause stomach ulcers, kidney problems, and heart issues. It should be used for the shortest duration possible. - Myth: Bromelain is just a placebo and has no real effect.
Fact: Bromelain has anti-inflammatory properties and may help reduce swelling, though evidence is moderate. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of stomach bleeding and liver damage. It should be avoided.
🔄 Alternative Options
Generic Alternatives
- Bromelain + Diclofenac combination generics available
Brand Alternatives
- Not applicable