moxicip br eye drop - Bromfenac (0.09% w/v) + Moxifloxacin (0.5% w/v) medicine

i-brom plus ophthalmic solution: Comprehensive Guide

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🏭 Cipla Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for postoperative use.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain that does not improve with medication
  • Sudden vision loss or significant blurring
  • Increased redness, swelling, or discharge from the eye
  • Signs of allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing
  • Eye injury or trauma
  • New or worsening eye symptoms after starting the medicine

If experiencing severe symptoms, call emergency services immediately.

What is moxicip br eye drop used for?

This medicine is a combination eye drop containing bromfenac (an anti-inflammatory) and moxifloxacin (an antibiotic). It is used after eye surgery to reduce inflammation and prevent infection. It is applied topically to the eye as directed by your doctor.

  • Generic Name: Bromfenac (0.09% w/v) + Moxifloxacin (0.5% w/v)
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 moxicip br eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों की सर्जरी के बाद सूजन और दर्द को कम करने और संक्रमण को रोकने के लिए इस्तेमाल की जाती है। इसमें ब्रोमफेनाक (सूजन कम करने वाला) और मॉक्सीफ्लोक्सासिन (एंटीबायोटिक) होता है। यह आंखों में डालने वाली दवा है और इसे डॉक्टर के निर्देशानुसार ही इस्तेमाल करना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में आंखों में जलन, लालिमा, धुंधली दृष्टि, पानी आना और आंखों में कुछ महसूस होना शामिल है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें आंखों में तेज दर्द, दृष्टि में कमी, या एलर्जी प्रतिक्रिया शामिल हो सकती है। अगर आपको ऐसा कुछ हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डालने से पहले और बाद में हाथ धोएं। ड्रॉपर की नोक को आंख या किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनने से पहले लेंस निकालें और दवा डालने के 10 मिनट बाद ही लेंस पहनें। दवा डालने के बाद कुछ समय के लिए धुंधली दृष्टि हो सकती है, इसलिए वाहन न चलाएं। डॉक्टर के बताए समय से ज्यादा इसका इस्तेमाल न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 moxicip br eye drop Uses & Benefits

[{"condition":"Postoperative ocular inflammation and infection prophylaxis","description":"Used after cataract surgery or other eye surgeries to reduce inflammation and prevent bacterial infection.","evidence":"Well-established"},{"condition":"Postoperative pain and swelling after ocular surgery","description":"Helps alleviate pain and swelling associated with surgical trauma to the eye.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Treatment of bacterial conjunctivitis","description":"May be used off-label for bacterial conjunctivitis when both anti-inflammatory and antibacterial effects are desired, though typically not first-line.","evidence":"Limited"}]

Primary treatment for: Postoperative ocular inflammation and infection

Also treats: Cataract surgery, Refractive surgery, Corneal surgery

📋 Drug Information

Generic Name(s)Bromfenac (0.09% w/v) + Moxifloxacin (0.5% w/v)
Brand Namemoxicip br eye drop
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action Class
Route of AdministrationOphthalmic
StorageStore at 2-8°C (36-46°F) in a refrigerator. Do not freeze. Keep the bottle tightly closed when not in use. Protect from light.
Shelf LifeRefer to the expiry date on the packaging. Discard 4 weeks after opening.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this medicine to prevent contamination.
2
Do not touch the dropper tip to your eye or any surface, as this can introduce bacteria.
3
If you wear contact lenses, remove them before application and wait at least 10 minutes before reinserting.
4
Apply gentle pressure on the inner corner of your eye for 1-2 minutes after instilling the drop to reduce systemic absorption.
5
Do not use this medicine for longer than prescribed, as prolonged use can lead to antibiotic resistance.
6
If you are using other eye drops, wait at least 5-10 minutes between applications.
7
Report any worsening eye pain, redness, or vision changes to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Eye pain after surgery
This medicine is commonly prescribed for this.
Likely Use
Eye redness and swelling
This medicine helps reduce these symptoms.
Likely Use
Blurred vision
This medicine may cause temporary blurred vision, but persistent blurred vision should be evaluated.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromfenac and moxifloxacin are absorbed systemically to a limited extent after topical ocular administration. Systemic absorption is generally low but can occur via the nasolacrimal duct. Not established from the available information for specific pharmacokinetic parameters.
DistributionAfter ocular instillation, both drugs distribute into ocular tissues, including the cornea, aqueous humor, and conjunctiva. Protein binding for bromfenac is approximately 99.5%, while moxifloxacin is about 30-50% bound to plasma proteins.
Protein BindingBromfenac: approximately 99.5% bound to plasma proteins. Moxifloxacin: approximately 30-50% bound to plasma proteins.
MetabolismBromfenac is metabolized primarily by CYP2C9 to inactive metabolites. Moxifloxacin undergoes glucuronide and sulfate conjugation; it is not significantly metabolized by cytochrome P450 enzymes.
Half-LifeBromfenac: approximately 1.5 hours in plasma. Moxifloxacin: approximately 12 hours in plasma after systemic administration.
ExcretionBromfenac metabolites are excreted primarily in urine and feces. Moxifloxacin is excreted unchanged in urine and feces, and also as conjugated metabolites.
BioavailabilitySystemic bioavailability after ocular administration is low. Not established from the available information for exact values.
Onset of ActionAnti-inflammatory effects of bromfenac may begin within hours of application. Antibacterial effects of moxifloxacin start immediately upon contact with susceptible bacteria.
Peak Plasma TimeBromfenac: approximately 0.5-1 hour after ocular administration. Moxifloxacin: approximately 1-2 hours after ocular administration.
Duration of ActionAnti-inflammatory effect of bromfenac lasts approximately 12-24 hours. Antibacterial effect of moxifloxacin persists as long as effective concentrations are maintained in ocular tissues.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Bromfenac is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever in the eye. Moxifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Together, they provide anti-inflammatory and antibacterial action in the eye.

Mechanism Steps

1
Bromfenac inhibits cyclooxygenase: Bromfenac binds to and reversibly inhibits COX-1 and COX-2 enzymes, reducing the conversion of arachidonic acid to prostaglandin H2, a precursor of inflammatory mediators.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to less vasodilation, vascular permeability, and pain sensitization in ocular tissues.
3
Moxifloxacin inhibits bacterial DNA enzymes: Moxifloxacin binds to DNA gyrase and topoisomerase IV, blocking bacterial DNA replication and causing double-strand breaks.
4
Bacterial cell death: The inhibition of DNA replication leads to rapid bacterial cell death, preventing infection.

💡 How to Take moxicip br eye drop

Strength: Ophthalmic solution containing bromfenac 0.09% w/v and moxifloxacin 0.5% w/v.

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and look up.
4Pull down your lower eyelid to create a small pouch.
5Hold the dropper above the eye and squeeze one drop into the pouch.
6Close your eye gently and press the inner corner with your finger for 1-2 minutes to prevent drainage.
7Do not blink or rub your eye.
8Replace the cap tightly after use.
9Wash your hands again.

Dosage Information

Adult DosageThe usual adult dose is one drop instilled into the affected eye(s) as directed by your ophthalmologist. Typically, one drop is applied twice daily for 14 days after surgery, but the exact regimen must be individualized by a qualified clinician based on the specific indication, surgical procedure, and patient response. Do not exceed the prescribed frequency or duration.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. Use as prescribed by your doctor.
Renal ImpairmentNo dosage adjustments are required for renal impairment with ocular use. Systemic absorption is low.
Hepatic ImpairmentNo dosage adjustments are required for hepatic impairment with ocular use. Systemic absorption is low.
Maximum Daily DoseThe maximum daily dose is typically two drops per affected eye per day, but this must be confirmed by your prescribing doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of moxicip br eye drop

✅ Common Side Effects

Transient burning or stinging (Common (5-10%))
Usually resolves within minutes. If persistent, consult your doctor.
Eye redness (Common (5-10%))
May subside with continued use. If worsening, contact your doctor.
Blurred vision (Common (5-10%))
Avoid driving until vision clears. If persistent, consult your doctor.
Watery eyes (Common (5-10%))
Usually temporary. If excessive, consult your doctor.
Foreign body sensation (Common (5-10%))
May resolve with continued use. If severe, consult your doctor.

🚨 Serious Side Effects

Corneal thinning or perforation (Rare (<0.1%))
Seek immediate medical attention if you experience severe eye pain, vision loss, or a feeling that something is stuck in your eye.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you develop rash, itching, swelling of face, lips, tongue, or throat, or difficulty breathing.
Superinfection (Rare (<0.1%))
Consult your doctor if you notice new or worsening eye symptoms such as increased redness, pain, or discharge.

⚠️ Rare Side Effects

Corneal melt
Seek immediate ophthalmologic care.
Tendon rupture
Report any tendon pain or swelling to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other ocular NSAIDs Major
Ocular corticosteroids Moderate
Other fluoroquinolones Moderate

🚨 Major Interactions

  • Other topical ocular NSAIDs
  • Oral anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Other fluoroquinolones
  • Corticosteroids (ocular)

🍷 Alcohol Interaction

No known significant interaction with alcohol when used as eye drops. However, alcohol may worsen dry eye symptoms. Consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to bromfenac, moxifloxacin, or other fluoroquinolones","History of NSAID-induced allergic reaction","Viral, fungal, or mycobacterial eye infections","Use in children under 18 years (safety not established)"]

⚠️ Warnings & Precautions

["For ophthalmic use only. Do not inject or ingest.","Prolonged use may lead to bacterial resistance.","May cause temporary blurred vision; avoid driving until clear.","Remove contact lenses before use and wait 10 minutes before reinsertion.","Do not touch dropper tip to any surface to avoid contamination.","Use with caution in patients with corneal disease or after complicated surgery.","NSAIDs may slow corneal healing.","Consult doctor if symptoms worsen or persist."]

🤱 Lactation Safety

It is not known whether bromfenac or moxifloxacin are excreted in human milk. Caution should be exercised when administered to a nursing woman. Consult your doctor.

💊 Overdose Management

Overdose is unlikely with ocular use. If accidental ingestion occurs, seek medical attention. Symptoms may include nausea, vomiting, and abdominal pain. Contact a poison control center or emergency room immediately.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Wash your hands thoroughly before and after applying this medicine. Tilt your head back, pull down the lower eyelid to form a pouch, and instill one drop into the affected eye as directed by your doctor. Avoid touching the dropper tip to your eye, eyelid, or any surface to prevent contamination. Do not use this medicine while wearing contact lenses; remove lenses before application and wait at least 10 minutes before reinserting. Do not use this medicine for longer than prescribed, as prolonged use may increase the risk of side effects and antibiotic resistance. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery if your vision is temporarily blurred after application. Keep this medicine out of reach of children. Do not use this medicine after the expiry date or if the solution changes color or becomes cloudy.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects. Use with caution and monitor for any adverse reactions. No specific dose adjustment is required for ocular use.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant or are pregnant. The safety of this medicine during pregnancy has not been fully established. Use only if clearly needed.

🏥 Post-Surgery Considerations

This medicine is commonly prescribed after eye surgery. Follow your surgeon's instructions carefully. Do not rub your eye or get water in it. Attend all follow-up appointments.

🦷 Dental Procedures

Inform your dentist if you are using this medicine. No specific precautions are typically needed for dental work, but good hygiene is important.

💚 Lifestyle Tips for Better Results

🏃
Avoid rubbing your eyes to prevent irritation and infection.
🥗
Wear sunglasses outdoors to protect your eyes from sunlight and wind.
😴
Maintain good hand hygiene, especially before touching your eyes.
💧
Follow a healthy diet rich in vitamins A, C, and E for eye health.
🧘
Get adequate sleep to support healing.
🌞
Avoid swimming or using hot tubs until your doctor approves.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase eye pressure or risk eye injury until your doctor says it is safe. Gentle walking is usually fine.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids, such as fish and flaxseed.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated to maintain tear production.
Limit caffeine and alcohol, which can contribute to dry eyes.

💼 Impact on Daily Work & Life

You may experience temporary blurred vision after applying the drops. Avoid driving or operating heavy machinery until your vision is clear. Most people can return to desk work shortly after surgery, but follow your doctor's advice.

🛑 When to Stop This Medicine

Stop using this medicine only after completing the prescribed course or as directed by your doctor. Do not stop early, as this may lead to recurrence of infection or inflammation. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended beyond the prescribed duration. Prolonged use of antibiotics can lead to bacterial resistance and superinfection. NSAIDs may increase the risk of corneal adverse effects. Regular follow-up with your ophthalmologist is advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lubricating eye drops

Can help with dryness and discomfort but do not treat infection or inflammation.

Evidence: Well-established
Cold compresses

May help reduce swelling and soothe the eye.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor before receiving any vaccine while using this medicine.

📦 Storage Guide

✅ DO

Store in a refrigerator at 2-8°C

❌ DON'T

Do not freeze

✅ DO

Keep the bottle tightly closed when not in use

❌ DON'T

Do not leave the cap off

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✅ DO

Discard 4 weeks after opening

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place, and if traveling to a hot climate, use a cool pack to maintain the recommended temperature (2-8°C). Keep it in your carry-on luggage to avoid extreme temperatures in checked baggage. If crossing time zones, continue your regular dosing schedule as prescribed; consult your doctor if unsure.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man underwent cataract surgery and was prescribed this medicine.
He used the drops as directed twice daily. Within a few days, his eye redness and swelling decreased significantly. He experienced mild stinging upon application but it resolved quickly. He completed the full course without any serious side effects.
💡 Lesson: Consistent use as prescribed helps achieve optimal recovery after eye surgery.
👤 A 50-year-old woman with a history of dry eyes used this medicine after refractive surgery.
She initially experienced increased dryness and blurring. She consulted her doctor, who recommended using lubricating eye drops in between. Her symptoms improved, and she completed the treatment successfully.
💡 Lesson: Communicate any new or worsening symptoms to your doctor; adjustments can be made for comfort.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief from inflammation within a few hours, but the full effect may take a few days. Complete the full course as prescribed.

Q: Can I wear contact lenses while using this medicine?

A: No, you should not wear contact lenses while using this medicine. Remove lenses before application and wait at least 10 minutes before reinserting.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for dry eyes?
  • How long does it take to work?
  • Can I drive after using this medicine?
  • What if I miss a dose?
  • Is it safe to use with other eye drops?
  • Can I use it while breastfeeding?

🔄 Substitutes for moxicip br eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any eye infection.
    Fact: It is specifically for postoperative use and should only be used as prescribed by an ophthalmologist.
  • Myth: More drops mean faster healing.
    Fact: Using more than prescribed can increase side effects and antibiotic resistance.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Bromfenac + Moxifloxacin","primary_use":"Postoperative inflammation and infection","route":"Ophthalmic"},{"medicine":"Bromfenac alone","composition":"Bromfenac","primary_use":"Inflammation only","route":"Ophthalmic"},{"medicine":"Moxifloxacin alone","composition":"Moxifloxacin","primary_use":"Infection only","route":"Ophthalmic"}]

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