movalgesic mr 500mg/30mg/500mg tablet - Chlorzoxazone (500mg) + Diclofenac (30mg) medicine

Movalgesic MR 500mg/30mg Tablet: Comprehensive Medicine Guide

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🏭 Lifecare Neuro Products Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for combination use in acute musculoskeletal pain.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is movalgesic mr 500mg/30mg/500mg tablet used for?

This medicine is a combination of chlorzoxazone (a muscle relaxant) and diclofenac (an NSAID) used for short-term relief of acute musculoskeletal pain and muscle spasm. It works by reducing muscle spasm and inflammation. Take it with food to avoid stomach upset and follow your doctor's instructions.

  • Generic Name: Chlorzoxazone (500mg) + Diclofenac (30mg)
  • Manufacturer: Lifecare Neuro Products Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 movalgesic mr 500mg/30mg/500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोरज़ोक्साज़ोन और डाइक्लोफेनाक का संयोजन है, जिसका उपयोग मांसपेशियों में ऐंठन और दर्द के इलाज के लिए किया जाता है। यह मांसपेशियों को आराम देती है और सूजन को कम करती है। यह आमतौर पर गर्दन, कमर और जोड़ों के दर्द में राहत के लिए दी जाती है। इसे भोजन के साथ लें ताकि पेट में जलन न हो। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, चक्कर आना, नींद आना और मुँह सूखना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, गुर्दे की समस्या, यकृत की समस्या और एलर्जी प्रतिक्रिया हो सकती है। यदि आपको काला मल, खून की उल्टी, पेट में तेज दर्द, पेशाब कम आना, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ न लें। यदि आपको नींद या चक्कर आते हैं तो वाहन न चलाएँ। गर्भवती और स्तनपान कराने वाली महिलाएँ डॉक्टर की सलाह के बिना इसका उपयोग न करें। बच्चों की पहुँच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 movalgesic mr 500mg/30mg/500mg tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and muscle spasm associated with strains, sprains, and other soft tissue injuries.","evidence":"Well-established"},{"condition":"Muscle spasm","description":"Reduces excessive muscle tone and spasm through central action of chlorzoxazone.","evidence":"Well-established"},{"condition":"Low back pain","description":"Provides short-term relief of acute low back pain with associated muscle spasm.","evidence":"Well-established"},{"condition":"Tension headache","description":"May help relieve tension-type headaches with muscular component.","evidence":"Limited"},{"condition":"Post-traumatic pain","description":"Used for pain following minor trauma or surgery.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Fibromyalgia","description":"Sometimes used off-label for pain management in fibromyalgia, but evidence is limited.","evidence":"Limited"},{"condition":"Osteoarthritis flare","description":"May be used short-term for osteoarthritis pain flares, though not first-line.","evidence":"Limited"}]

Primary treatment for: Musculoskeletal pain and muscle spasm

Also treats: Low back pain, Tension headache, Post-traumatic pain

📋 Drug Information

Generic Name(s)Chlorzoxazone (500mg) + Diclofenac (30mg)
Brand Namemovalgesic mr 500mg/30mg/500mg tablet
ManufacturerLifecare Neuro Products Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Do not drive or operate machinery if you feel drowsy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Muscle spasm
This medicine is indicated for muscle spasm.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorzoxazone is absorbed from the gastrointestinal tract. Diclofenac is also absorbed from the gastrointestinal tract. Food may delay absorption of diclofenac but does not significantly reduce overall bioavailability.
DistributionChlorzoxazone is distributed widely in body tissues. Diclofenac is highly bound to plasma proteins and distributes into synovial fluid.
Protein BindingChlorzoxazone: not established from the available information. Diclofenac: greater than 99% bound to plasma proteins, primarily albumin.
MetabolismChlorzoxazone is extensively metabolized in the liver, primarily by CYP2E1 and CYP1A2. Diclofenac is metabolized in the liver by CYP2C9 to 4'-hydroxydiclofenac and by other pathways.
Half-LifeChlorzoxazone: approximately 1-2 hours. Diclofenac: approximately 1-2 hours.
ExcretionChlorzoxazone metabolites are excreted mainly in urine. Diclofenac metabolites are excreted in urine and bile.
BioavailabilityChlorzoxazone: not established from the available information. Diclofenac: approximately 50-60% due to first-pass metabolism.
Onset of ActionChlorzoxazone: within 1 hour. Diclofenac: within 30-60 minutes for analgesic effect.
Peak Plasma TimeChlorzoxazone: 1-2 hours. Diclofenac: 1-2 hours.
Duration of ActionChlorzoxazone: 4-6 hours. Diclofenac: 4-6 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Chlorzoxazone acts primarily on the central nervous system, likely by inhibiting polysynaptic reflexes in the spinal cord and brainstem, reducing muscle spasm. Diclofenac is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), decreasing prostaglandin synthesis and thereby reducing inflammation, pain, and fever.

Mechanism Steps

1
Central muscle relaxation: Chlorzoxazone acts on the central nervous system to inhibit polysynaptic reflex arcs, reducing muscle spasm and associated pain.
2
COX enzyme inhibition: Diclofenac inhibits cyclooxygenase enzymes, blocking the conversion of arachidonic acid to prostaglandins.
3
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to reduced inflammation, pain, and fever.
4
Combined symptomatic relief: The two actions together provide relief from both muscle spasm and inflammatory pain.

💡 How to Take movalgesic mr 500mg/30mg/500mg tablet

Strength: Each tablet contains Chlorzoxazone 500 mg and Diclofenac 30 mg.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take with food or milk to reduce stomach upset.
4Do not crush, chew, or break the tablet.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two to three times daily, or as directed by your physician. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with food to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Use with caution and at the lowest effective dose. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum daily dose should not exceed 3 tablets in 24 hours, or as prescribed by your doctor. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of movalgesic mr 500mg/30mg/500mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult your doctor.
Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Consult if severe.
Headache (Common (5-10%))
Usually resolves. Stay hydrated. Consult if persistent.
Stomach pain (Common (5-10%))
Take with food or milk. Consult if severe or persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Kidney impairment (Rare (<0.1%))
Report decreased urine output or swelling. Seek medical attention.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue. Seek medical attention.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, throat, or difficulty breathing.
Cardiovascular events (Rare (<0.1%))
Seek immediate care for chest pain, shortness of breath, or weakness on one side.

⚠️ Rare Side Effects

Blood disorders
Report unusual bruising or bleeding. Seek medical attention.
Pancreatitis
Seek immediate care for severe abdominal pain radiating to back.
Severe skin reactions
Seek emergency care for rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
Antihypertensives Moderate
Diuretics Moderate
SSRIs Moderate
Fluconazole Moderate
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • Antihypertensives
  • Diuretics
  • SSRIs
  • CYP2C9 inhibitors (e.g., fluconazole)

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and may enhance drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorzoxazone, diclofenac, or other NSAIDs","Active peptic ulcer disease or history of recurrent ulcers","Severe renal impairment","Severe hepatic impairment","Asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Coronary artery bypass graft surgery","Third trimester of pregnancy"]

⚠️ Warnings & Precautions

["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with cardiovascular risk factors unless benefits outweigh risks.","May cause drowsiness; avoid driving or operating machinery.","Do not use for prolonged periods without medical supervision.","Monitor for signs of gastrointestinal bleeding.","Use with caution in patients with asthma.","Avoid alcohol consumption.","Inform your doctor if you have kidney or liver disease."]

🤱 Lactation Safety

Not established from the available information. Diclofenac is excreted in breast milk in small amounts. Chlorzoxazone safety in breastfeeding is not established. Consult your doctor before use.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach irritation. Avoid alcohol and other NSAIDs while on this medicine. Inform your doctor about all other medications you are taking, especially blood thinners, corticosteroids, and antihypertensives. Do not drive or operate heavy machinery if you feel drowsy or dizzy. Use with caution in the elderly and in those with kidney, liver, or heart disease. Do not use this medicine if you are pregnant, especially in the third trimester, or breastfeeding without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal, renal, and cardiovascular side effects. Use with caution and at the lowest effective dose.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. This medicine is not recommended during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

Use with caution after surgery, especially if you are at risk of bleeding. Consult your surgeon.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may worsen your condition while taking this medicine. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney problems, liver toxicity, and cardiovascular events. Regular monitoring of liver and kidney function is advised. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Heat or cold therapy

May help relieve muscle spasm and pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with acute low back pain
Was prescribed this medicine for severe muscle spasm. He experienced drowsiness initially but it subsided after a few days. He was advised not to drive during this period.
💡 Lesson: Drowsiness is a common side effect that often resolves, but caution is needed with driving.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes, but full effects may take a few days.

Q: Can I take this medicine on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any type of pain.
    Fact: This medicine is specifically for musculoskeletal pain and muscle spasm. It is not effective for all types of pain.
  • Myth: It is safe to take this medicine for a long time.
    Fact: Prolonged use can increase the risk of serious side effects such as gastrointestinal bleeding, kidney problems, and cardiovascular events.
  • Myth: You can drink alcohol while taking this medicine.
    Fact: Alcohol increases the risk of gastrointestinal bleeding and drowsiness. Avoid alcohol.

🔄 Alternative Options

Generic Alternatives

  • Chlorzoxazone + Diclofenac combination tablets

📊 Comparison with Similar Medicines

[{"medicine":"Chlorzoxazone + Diclofenac","composition":"Chlorzoxazone 500 mg + Diclofenac 30 mg","uses":"Musculoskeletal pain and spasm","notes":"Combination of muscle relaxant and NSAID"},{"medicine":"Chlorzoxazone + Aceclofenac","composition":"Chlorzoxazone 500 mg + Aceclofenac 100 mg","uses":"Musculoskeletal pain and spasm","notes":"Aceclofenac may have better GI tolerance"},{"medicine":"Chlorzoxazone + Ibuprofen","composition":"Chlorzoxazone 500 mg + Ibuprofen 400 mg","uses":"Musculoskeletal pain and spasm","notes":"Ibuprofen is another NSAID"}]

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