Dolocaf Extra Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is metacin exs tablet used for?
This medicine is a combination of Paracetamol 650 mg and Caffeine 50 mg used for relief of mild to moderate pain and fever. It works by reducing pain and enhancing alertness.
- Generic Name: Caffeine (50mg) + Paracetamol (650mg)
- Manufacturer: Chemosyn Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 metacin exs tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और कैफीन का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, माइग्रेन, दांत दर्द, मासिक धर्म में होने वाले दर्द, मांसपेशियों में दर्द और सर्दी-जुकाम से जुड़े दर्द में राहत देती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, अनिद्रा, बेचैनी और घबराहट शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन जिगर की क्षति, त्वचा पर गंभीर प्रतिक्रियाएं और एलर्जी हो सकती हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा की अनुशंसित खुराक से अधिक न लें। अधिक मात्रा में लेने से जिगर को गंभीर नुकसान हो सकता है। इस दवा के साथ शराब का सेवन न करें। बुखार के लिए 3 दिन से अधिक और दर्द के लिए 10 दिन से अधिक उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।
💊 metacin exs tablet Uses & Benefits
[{"condition":"Headache","description":"Relieves mild to moderate headache, including tension headaches.","evidence":"Well-established"},{"condition":"Migraine","description":"Helps alleviate migraine pain; caffeine may enhance the effect of paracetamol.","evidence":"Well-established"},{"condition":"Toothache","description":"Provides temporary relief from dental pain.","evidence":"Well-established"},{"condition":"Menstrual cramps","description":"Reduces pain associated with menstruation.","evidence":"Well-established"},{"condition":"Muscle aches","description":"Relieves minor muscle pain and soreness.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever due to various causes.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-operative pain","description":"Sometimes used as an adjunct for mild post-operative pain.","evidence":"Limited"},{"condition":"Osteoarthritis pain","description":"May be used for short-term relief of osteoarthritis pain when other options are unsuitable.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Headache, Migraine, Toothache, Menstrual cramps, Muscle aches
📋 Drug Information
| Generic Name(s) | Caffeine (50mg) + Paracetamol (650mg) |
| Brand Name | metacin exs tablet |
| Manufacturer | Chemosyn Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. Caffeine is a methylxanthine that blocks adenosine receptors, leading to increased alertness and enhanced analgesic effect of paracetamol. The combination provides greater pain relief than paracetamol alone.
Mechanism Steps
💡 How to Take metacin exs tablet
Strength: Tablet: Paracetamol 650 mg + Caffeine 50 mg
Dosage Information
| Adult Dosage | The usual adult dose is 1 tablet every 6 to 8 hours as needed for pain or fever, not to exceed 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to side effects. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction or avoidance may be necessary. Consult a doctor. |
| Maximum Daily Dose | Maximum 4 tablets in 24 hours (2600 mg paracetamol and 200 mg caffeine). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of metacin exs tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Cimetidine | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- Other paracetamol-containing products
⚡ Moderate Interactions
- Carbamazepine
- Phenytoin
- Rifampicin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may worsen side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to paracetamol or caffeine","Severe liver disease","Severe kidney disease","Alcoholism"]
⚠️ Warnings & Precautions
["Do not exceed recommended dose.","Avoid alcohol.","Use with caution in liver or kidney disease.","Consult doctor if symptoms persist beyond 3 days for fever or 10 days for pain.","Do not use with other paracetamol-containing products."]
🤱 Lactation Safety
Paracetamol and caffeine are excreted in breast milk in small amounts. Consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose of paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin. Seek immediate medical attention. Treatment includes activated charcoal, N-acetylcysteine, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Do not exceed the recommended dose of this medicine. Taking too much Paracetamol can cause serious liver damage. Avoid consuming alcohol while taking this medicine as it increases the risk of liver toxicity. Do not use this medicine for more than 3 days for fever or 10 days for pain without consulting a doctor. If you have liver or kidney disease, or if you are pregnant or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Do not take other products containing Paracetamol while on this medicine to avoid overdose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to side effects. Use with caution and consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy or if you become pregnant while taking this medicine.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions while taking this medicine. However, if you experience dizziness or fatigue, avoid strenuous activities.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if symptoms persist or worsen, or if you experience any serious side effects.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of paracetamol may increase the risk of liver and kidney damage. Regular monitoring of liver and kidney function may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help with tension headaches.
Evidence: Some evidence💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. Consult your doctor for specific advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. No time zone adjustments are needed for this medicine. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after taking it.
A: It is best taken with food to reduce stomach upset.
A: Consult your doctor before use during pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for metacin exs tablet
View AllAlternative brands with exact same active ingredient:
-
algina plus 50mg/650mg tabletGeno Pharmaceuticals Ltd ₹12.17 46.2% CHEAPER
-
aekil plus tabletAgron Remedies Pvt Ltd ₹14.63 35.4% CHEAPER
-
diclowin plus pr tabletWings Biotech Ltd ₹20.00 11.6% CHEAPER
-
leemol activ 50mg/650mg tabletLeeford Healthcare Ltd ₹28.13 24.3% COSTLIER
-
senmol active 50mg/650mg tabletSenen Biotech ₹28.13 24.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: It is safe to take this medicine with alcohol.
Fact: No, alcohol increases the risk of liver damage. - Myth: This medicine can be taken for long periods without consulting a doctor.
Fact: Prolonged use should be under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Paracetamol + Caffeine tablets
Brand Alternatives
- Dolocaf Extra Tablet