Estore 25mg Tablet (Mesterolone): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes, dark urine, or pale stools, which may indicate liver problems.
- Severe upper abdominal pain, especially with nausea or vomiting.
- Swelling, pain, or redness in one leg, which may indicate a blood clot.
- Sudden chest pain, breathlessness, or coughing up blood, which may indicate a clot in the lungs.
- A painful erection lasting more than four hours, which is a medical emergency.
- Severe mood changes, agitation, hallucinations, or thoughts of harming yourself.
- Swelling of the face, lips, or throat, or difficulty breathing, which may indicate a severe allergic reaction.
- Unusual weight gain, severe swelling, or a rapid rise in blood pressure.
If experiencing severe symptoms, call emergency services immediately.
What is mestilon tablet used for?
This medicine contains mesterolone 25 mg, a synthetic male hormone (androgen) used in men to treat low testosterone levels, delayed puberty, low sex drive, and some cases of male infertility. It works by binding to androgen receptors and mimicking natural testosterone. It is a prescription-only medicine and must never be used for bodybuilding or without medical supervision.
- Generic Name: Mesterolone (25mg)
- Manufacturer: Sanzyme Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 mestilon tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेस्टेरोलोन 25 मिलीग्राम की गोली है, जो पुरुषों में टेस्टोस्टेरोन हार्मोन की कमी से जुड़ी समस्याओं के इलाज में इस्तेमाल की जाती है। इसका उपयोग पुरुषों में कामेच्छा कम होना, मर्दाना लक्षणों का विकास न होना, देर से यौवन आना, और कुछ मामलों में शुक्राणु उत्पादन या प्रजनन क्षमता से जुड़ी समस्याओं में किया जाता है। यह दवा शरीर में प्राकृतिक पुरुष हार्मोन की तरह काम करती है और एंड्रोजन रिसेप्टर से जुड़कर मर्दाना शारीरिक लक्षणों, मांसपेशियों और हड्डियों को सहारा देती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और महिलाओं, खासकर गर्भवती या स्तनपान कराने वाली महिलाओं को यह दवा नहीं लेनी चाहिए। बॉडीबिल्डिंग या बिना डॉक्टर की सलाह के इसका इस्तेमाल करना खतरनाक हो सकता है क्योंकि इससे लिवर, हृदय और हार्मोन से जुड़ी गंभीर समस्याएं हो सकती हैं।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं, जैसे मुँहासे, तैलीय त्वचा, चेहरे या शरीर पर बाल बढ़ना, मूड में बदलाव, चिड़चिड़ापन, कामेच्छा में बदलाव और शरीर में पानी जमा होने से हल्की सूजन। कुछ पुरुषों में स्तनों में कोमलता या बढ़ोतरी भी हो सकती है, जिसकी जानकारी तुरंत डॉक्टर को देनी चाहिए। गंभीर दुष्प्रभावों में लिवर की समस्या, पीलिया, रक्तचाप बढ़ना, कोलेस्ट्रॉल में बदलाव, खून के थक्के बनना और कभी-कभी लंबे समय तक दर्दभरी इरेक्शन होना शामिल है। अगर आंखों या त्वचा का रंग पीला पड़े, पेशाब गहरा हो, सीने में दर्द, सांस लेने में तकलीफ, एक पैर में सूजन या चार घंटे से ज्यादा दर्दभरी इरेक्शन हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: यह दवा सिर्फ डॉक्टर के पर्चे पर और बताई गई मात्रा में ही लें। इसे पानी के साथ, खाने के बाद लेना बेहतर होता है ताकि पेट में जलन न हो। इसका इस्तेमाल बॉडीबिल्डिंग, खेल प्रदर्शन या मांसपेशियां बढ़ाने के लिए बिल्कुल न करें, क्योंकि इससे लिवर, हृदय और हार्मोन को गंभीर नुकसान हो सकता है। महिलाएं, खासकर गर्भवती, गर्भधारण की योजना बनाने वाली या स्तनपान कराने वाली महिलाएं यह दवा न लें। प्रोस्टेट कैंसर, ब्रेस्ट कैंसर या गंभीर लिवर रोग वाले पुरुषों को यह दवा नहीं लेनी चाहिए। अपने डॉक्टर को अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। इस दवा के साथ शराब न पिएं। नियमित जांच के लिए डॉक्टर के पास जाते रहें ताकि लिवर, खून, कोलेस्ट्रॉल और प्रोस्टेट की निगरानी हो सके। दवा को कमरे के तापमान पर, धूप और नमी से दूर, बच्चों की पहुंच से बाहर रखें।
💊 mestilon tablet Uses & Benefits
[{"condition":"Male hypogonadism","description":"This medicine is used to replace or support male hormone levels in men whose bodies do not produce enough natural testosterone, helping to restore sexual function, mood, and male physical characteristics.","evidence":"Established clinical use"},{"condition":"Delayed puberty in boys","description":"It may be prescribed to boys with delayed puberty to help trigger the development of secondary sexual characteristics such as voice deepening, facial hair, and genital growth.","evidence":"Established clinical use"},{"condition":"Male infertility related to low androgen levels","description":"In some men with low androgen levels, this medicine may be used as part of a treatment plan to improve sperm production and fertility potential.","evidence":"Limited to selected cases"},{"condition":"Low libido in men","description":"This medicine can help improve sex drive in men whose low libido is linked to low androgen levels.","evidence":"Established in androgen deficiency"},{"condition":"Anaemia associated with androgen deficiency","description":"In certain clinical settings, this medicine may be used to support red blood cell production in men with anaemia related to low androgen levels.","evidence":"Limited clinical use"}]
Off-label uses: [{"condition":"Muscle wasting in chronic illness","description":"Sometimes considered to support muscle mass in men with wasting conditions, but this is not a standard approved use and requires specialist supervision.","evidence":"Limited"},{"condition":"Osteoporosis in men with hypogonadism","description":"May be used off-label to support bone density in men with low androgen levels, but dedicated bone medicines are usually preferred.","evidence":"Limited"}]
Primary treatment for: Male hypogonadism (low testosterone levels)
Also treats: Delayed puberty in boys, Male infertility related to low androgen levels, Low libido in men, Anaemia associated with androgen deficiency
📋 Drug Information
| Generic Name(s) | Mesterolone (25mg) |
| Brand Name | mestilon tablet |
| Manufacturer | Sanzyme Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Androgens |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in its original packaging. Keep it away from direct sunlight, heat, and moisture. Do not store it in the bathroom. Keep it out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is not established from the available information. Always check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by delivering mesterolone, a synthetic androgen that binds to androgen receptors inside target cells. Once bound, the receptor moves into the cell nucleus and switches on specific genes that control male sexual development, muscle protein building, red blood cell production, and bone strength. Because mesterolone is already an active androgen, it does not need to be converted by the body into testosterone to work, which is one reason it is used in men who need direct androgen support. It also suppresses the natural hormonal feedback loop that controls testosterone production, which is why it must be used under medical supervision.
Mechanism Steps
💡 How to Take mestilon tablet
Strength: Mesterolone 25 mg immediate-release tablet for oral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is determined by the doctor based on the condition being treated, the man's age, hormone levels, liver and kidney function, and response to treatment. Doses are often taken once daily or as directed, and the dose may be adjusted over time. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never change the dose or stop the medicine without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is only used in boys with delayed puberty under the close supervision of a specialist, and the dose is decided based on the child's age, stage of puberty, and clinical response. |
| Elderly Dosage | Older men may be more sensitive to the side effects of this medicine, especially fluid retention, raised blood pressure, prostate problems, and heart effects. The dose must be individualized by a qualified clinician based on age, kidney and liver function, prostate health, and other medical conditions. Regular monitoring is especially important in men above 65 years of age. |
| Renal Impairment | The dose of this medicine in people with kidney disease is not established from the available information. Because this medicine can cause fluid retention, it should be used with caution in people with kidney problems, and the dose must be individualized by a qualified clinician based on kidney function. |
| Hepatic Impairment | This medicine should not be used in people with severe liver disease. In people with mild to moderate liver impairment, the dose must be individualized by a qualified clinician based on liver function, and liver tests should be monitored regularly during treatment. |
| Maximum Daily Dose | The maximum daily dose of this medicine is not established from the available information and must be determined by a qualified clinician based on the individual patient's condition and response to treatment. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of mestilon tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Insulin | Major | |
| Other anabolic steroids | Major | |
| Corticosteroids | Moderate | |
| Cyclosporine | Moderate | |
| Levothyroxine | Moderate | |
| Antacids | Minor | |
| Paracetamol | Minor | |
| Alcohol | Major | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin and other blood thinners
- Insulin and oral diabetes medicines
- Other androgens or anabolic steroids
⚡ Moderate Interactions
- Corticosteroids
- Cyclosporine
- Thyroid hormone (levothyroxine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because both alcohol and mesterolone are processed by the liver, and combining them increases the risk of liver damage. Alcohol can also worsen mood changes, fluid retention, and blood pressure problems. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to mesterolone or any ingredient in the tablet","Prostate cancer or breast cancer in men","Severe liver disease","Women who are pregnant, planning pregnancy, or breastfeeding","Children before puberty unless specifically prescribed by a specialist for delayed puberty","Use for bodybuilding, sports performance, or non-medical muscle gain"]
⚠️ Warnings & Precautions
["This medicine is a prescription-only androgen and must never be used without medical supervision.","Do not use this medicine for bodybuilding or athletic performance, as unsupervised use can cause serious liver, heart, and hormonal harm.","Regular liver function tests are needed because this medicine can cause liver injury.","Men over 50 should have regular prostate checks, as androgens can worsen prostate problems.","This medicine can cause fluid retention and raise blood pressure, so people with heart or kidney disease need close monitoring.","This medicine can suppress natural testosterone production and reduce sperm count, especially with long-term use.","Avoid alcohol while taking this medicine to reduce the risk of liver damage.","Tell your doctor about all other medicines, supplements, and herbal products you take before starting this medicine.","Do not share this medicine with anyone else, even if they have similar symptoms.","Keep all follow-up appointments so your doctor can monitor your response and adjust the dose if needed."]
🤱 Lactation Safety
This medicine is not for use in breastfeeding women because androgens can pass into breast milk and may harm the baby. Women who are breastfeeding must not take this medicine.
💊 Overdose Management
If you or someone else takes too much of this medicine, seek medical help immediately or contact a poison control centre. Overdose may cause severe mood changes, fluid retention, high blood pressure, or liver problems. Do not try to make yourself vomit unless a healthcare professional tells you to. Take the medicine packaging with you to the hospital so the medical team knows exactly what was taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Never take two doses at the same time to make up for a missed dose, as this can increase the risk of side effects. If you miss several doses in a row, contact your doctor for advice.
Additional Safety Advice
This medicine must only be taken exactly as prescribed by a qualified doctor, and the dose should never be increased or decreased on your own. Take the tablet with water, preferably after food, to reduce the chance of stomach upset. Do not use this medicine for bodybuilding, athletic performance, or muscle gain, because such misuse can cause serious and sometimes permanent harm to your liver, heart, and hormone system. Women, especially those who are pregnant, planning pregnancy, or breastfeeding, must not take this medicine. Men with prostate cancer, breast cancer, or severe liver disease should not use this medicine. Tell your doctor about all other medicines, supplements, and herbal products you take, because this medicine can interact with blood thinners, diabetes medicines, and other hormonal products. Avoid alcohol while taking this medicine, as it increases the risk of liver problems. Keep all follow-up appointments so your doctor can check your liver function, blood counts, cholesterol, and prostate health. Store the tablets in their original packaging at room temperature, away from direct sunlight and moisture, and keep them out of reach of children. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose, and never take two doses together to make up for a missed one.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Men above 65 years of age may be more sensitive to the side effects of this medicine, especially fluid retention, raised blood pressure, prostate problems, and heart effects. Prostate examination and monitoring of liver, kidney, and heart function are especially important in this age group. The dose must be individualized by a qualified clinician.
🤰 Pregnancy Planning (TTC)
This medicine is not for use in women, including those planning pregnancy. Women who are trying to conceive must not take this medicine because it can harm a developing baby. Men taking this medicine who are planning a family should discuss fertility concerns with their doctor, as this medicine can affect sperm production.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthetist that you are taking this medicine before any surgery. This medicine can affect blood clotting, blood pressure, and blood sugar, which may influence surgical and anaesthetic decisions. Your doctor may advise you to stop the medicine for a short period before surgery. Do not stop it on your own without medical advice.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure, especially if you are having a tooth extraction or gum surgery. This medicine can affect blood clotting and blood pressure, which may influence dental treatment decisions. Your dentist may consult your doctor if needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is good for your overall health and can support the benefits of this medicine, but avoid excessive or intense training without proper rest and nutrition. If you experience dizziness, breathlessness, chest pain, or severe swelling during exercise, stop and seek medical advice. Always warm up and cool down properly, and stay well hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is not known to directly affect your ability to work or drive, but some people may experience mood changes, dizziness, or fatigue. If you feel unwell or notice any change in your concentration or mood, avoid driving or operating heavy machinery until you feel better. Discuss any work-related concerns with your doctor, especially if your job involves physical exertion or safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your response, test results, and the condition being treated. If you experience serious side effects such as jaundice, chest pain, severe mood changes, or a painful prolonged erection, stop the medicine and seek medical help immediately. Always consult your doctor before stopping or changing the dose.
📅 Long-Term Use Effects
Long-term use of this medicine can suppress the body's natural testosterone production, reduce sperm count, and increase the risk of liver problems, raised blood pressure, fluid retention, and prostate changes. Regular monitoring of liver function, blood counts, cholesterol, blood pressure, and prostate health is essential during long-term treatment. Your doctor will review the benefits and risks periodically and decide whether to continue, adjust, or stop the medicine.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Other forms of testosterone, such as injections, gels, or patches, may be used for male hypogonadism.
Evidence: Well-establishedWeight management, regular exercise, good sleep, and a balanced diet can support natural hormone balance.
Evidence: Well-establishedCorrecting underlying conditions such as thyroid problems, obesity, or sleep apnoea can improve testosterone levels.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions known with this medicine. However, if you are due for any vaccination, inform your doctor that you are taking this medicine. Routine vaccinations can generally be given as scheduled unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not store in the refrigerator unless your pharmacist tells you to.
✅ DO
Keep the tablets in their original container with the label intact.
❌ DON'T
Do not transfer the tablets to unmarked containers.
✅ DO
Keep the medicine away from direct sunlight and moisture.
❌ DON'T
Do not store it in the bathroom cabinet.
✅ DO
Keep the medicine out of reach of children and pets.
❌ DON'T
Do not use the medicine after the expiry date printed on the pack.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your doctor's prescription with you, especially for international travel, because androgens are controlled medicines in some countries. Store the tablets in a cool, dry place away from direct sunlight, and avoid leaving them in a hot car or checked luggage. If you are crossing time zones, ask your doctor how to adjust your dosing schedule. Carry enough medicine for your entire trip, plus a little extra in case of delays. Declare the medicine to customs if required and check the local rules of your destination before travelling.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some men notice early changes in mood, energy, and sex drive within one to two weeks, but full effects usually take several weeks to a few months. Your doctor will review your response at follow-up visits and adjust the treatment if needed.
A: No. This medicine is not for women, especially those who are pregnant, planning pregnancy, or breastfeeding. It can cause male-type changes in women and harm a developing baby.
A: Long-term use requires regular monitoring of liver function, blood counts, cholesterol, blood pressure, and prostate health. Your doctor will decide how long you should take it based on your condition and test results.
A: No. Alcohol should be avoided while taking this medicine because it increases the risk of liver damage and can worsen mood changes and fluid retention.
A: This medicine can suppress natural testosterone production and reduce sperm count, especially with long-term use. If you are being treated for infertility, your doctor will monitor your response with semen analysis and hormone tests.
A: No. Stopping suddenly can cause hormonal imbalance and worsening symptoms. Always consult your doctor before stopping or changing the dose.
🤔 Common Patient Concerns
🔄 Substitutes for mestilon tablet
View AllAlternative brands with exact same active ingredient:
-
restore 25mg tabletMicro Labs Ltd ₹187.50 22.3% COSTLIER
-
estore 25mg tabletEssar Formulations ₹275.00 79.4% COSTLIER
-
viropace tabletConsern Pharma Limited ₹342.19 123.2% COSTLIER
-
provironum tabletZydus Cadila ₹596.32 289% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a safe way to build muscle.
Fact: This medicine is a prescription androgen for medical conditions and can cause serious liver, heart, and hormonal harm if misused for bodybuilding. - Myth: This medicine can be taken by women for energy or weight loss.
Fact: This medicine is not for women and can cause male-type changes such as facial hair, voice deepening, and harm to a baby during pregnancy. - Myth: More medicine means faster results.
Fact: Taking more than the prescribed dose increases the risk of serious side effects without giving better results. - Myth: This medicine can be stopped suddenly without any problem.
Fact: Stopping suddenly can cause hormonal imbalance and worsening symptoms. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Mesterolone 25 mg tablet
Brand Alternatives
- Estore 25mg Tablet