Dubloc 10mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Sudden shortness of breath or chest pain
- Swelling or pain in one leg
- Severe headache with vision changes
- Yellowing of skin or eyes
- Severe abdominal pain
- Heavy vaginal bleeding that soaks a pad every hour
- Signs of allergic reaction such as rash, itching, or swelling of face or throat
If experiencing severe symptoms, call emergency services immediately.
What is megestone 10 mg tablet used for?
This medicine contains Medroxyprogesterone acetate 10 mg, a progestin hormone used to treat menstrual irregularities such as secondary amenorrhea and abnormal uterine bleeding. It works by regulating the uterine lining and is taken orally as prescribed by a doctor.
- Generic Name: Medroxyprogesterone acetate (10mg)
- Manufacturer: Rekvina Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 megestone 10 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेड्रोक्सीप्रोजेस्टेरोन एसीटेट 10 मिलीग्राम की गोली है, जिसका उपयोग मासिक धर्म की अनियमितताओं जैसे कि मासिक धर्म का न आना (सेकेंडरी अमेनोरिया) और असामान्य गर्भाशय रक्तस्राव के इलाज के लिए किया जाता है। यह हार्मोन प्रोजेस्टेरोन की तरह काम करती है और गर्भाशय की परत को नियमित करने में मदद करती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और गर्भावस्था के दौरान नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अनियमित योनि रक्तस्राव, स्तनों में कोमलता, मतली, सिरदर्द और मूड में बदलाव शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव जैसे खून के थक्के, गंभीर एलर्जी, या लिवर की समस्या दुर्लभ हैं, लेकिन अगर आपको सांस लेने में तकलीफ, सीने में दर्द, पैर में सूजन, या आंखों का पीलापन दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, अपने आप मात्रा न बदलें और न ही अचानक बंद करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। धूम्रपान न करें क्योंकि इससे खून के थक्के बनने का खतरा बढ़ सकता है। अन्य दवाओं के साथ लेने से पहले डॉक्टर को बताएं। नियमित जांच के लिए डॉक्टर के पास जाएं और किसी भी असामान्य लक्षण की सूचना दें।
💊 megestone 10 mg tablet Uses & Benefits
[{"condition":"Secondary amenorrhea","description":"This medicine is used to induce bleeding in women who have missed periods due to hormonal imbalance, after pregnancy and other causes have been excluded.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding","description":"It helps regulate the menstrual cycle and reduce heavy or prolonged bleeding caused by an imbalance between estrogen and progesterone.","evidence":"Well-established"},{"condition":"Endometrial hyperplasia prevention","description":"In women taking estrogen therapy who still have a uterus, this medicine is added to protect the uterine lining from overgrowth.","evidence":"Well-established"},{"condition":"Hormone replacement therapy","description":"It is used as the progestin component in combined hormone replacement therapy for menopausal symptoms in women with a uterus.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Catamenial epilepsy","description":"Sometimes prescribed off-label to reduce seizure frequency linked to the menstrual cycle, but evidence is limited.","evidence":"Limited"},{"condition":"Appetite stimulation in cachexia","description":"Occasionally used off-label to improve appetite in patients with cancer-related weight loss, but this is not a standard use.","evidence":"Limited"}]
Primary treatment for: Secondary amenorrhea
Also treats: Abnormal uterine bleeding, Endometrial hyperplasia, Menopausal hormone therapy
📋 Drug Information
| Generic Name(s) | Medroxyprogesterone acetate (10mg) |
| Brand Name | megestone 10 mg tablet |
| Manufacturer | Rekvina Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Progestins (First generation) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Keep out of reach of children. |
| Shelf Life | Typically 24 to 36 months from the date of manufacture, depending on the manufacturer. Check the expiry date on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a synthetic progestin that works by binding to progesterone receptors in target tissues, especially the endometrium. By mimicking the action of natural progesterone, it transforms the proliferative endometrium into a secretory phase and, when withdrawn, causes a predictable shedding of the uterine lining. It also suppresses gonadotropin release from the pituitary gland, which can inhibit ovulation at higher doses. At the 10 mg dose, its main effect is on the uterine lining rather than consistent ovulation suppression.
Mechanism Steps
💡 How to Take megestone 10 mg tablet
Strength: Medroxyprogesterone acetate 10 mg immediate-release tablet
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the condition being treated, your age, weight, and liver function. For secondary amenorrhea, a common regimen is 5 to 10 mg once daily for 5 to 10 days, starting on any day of the cycle. For abnormal uterine bleeding, the dose may be 5 to 10 mg daily for 10 to 14 days. For hormone replacement therapy, the dose is usually 2.5 to 5 mg daily. Always follow your doctor's prescription exactly. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially fluid retention and blood clot risk. The dose should be individualized by a clinician, and regular monitoring is advised. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor for fluid retention. Consult your doctor. |
| Hepatic Impairment | This medicine is contraindicated in severe liver disease. In mild to moderate hepatic impairment, dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose depends on the indication and is determined by your doctor. For most uses, doses above 10 mg per day are not recommended without specialist supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of megestone 10 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Rifampicin | Major | |
| Carbamazepine | Major | |
| Phenytoin | Moderate | |
| St John's wort | Moderate | |
| Ketoconazole | Minor |
🚨 Major Interactions
- Warfarin
- Rifampicin
- Carbamazepine
⚡ Moderate Interactions
- Phenytoin
- St John's wort
🍷 Alcohol Interaction
Alcohol may increase the risk of liver problems and can worsen side effects such as dizziness or mood changes. It is best to avoid alcohol or limit intake while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known or suspected pregnancy","Undiagnosed abnormal vaginal bleeding","History of blood clots (deep vein thrombosis, pulmonary embolism)","Active or recent liver disease","Known or suspected breast cancer","Hypersensitivity to medroxyprogesterone acetate or any component of the tablet"]
⚠️ Warnings & Precautions
["This medicine should not be used to prevent pregnancy at this dose.","Smoking increases the risk of blood clots; avoid smoking.","Use with caution if you have a history of depression, migraine, or seizure disorder.","Inform your doctor if you have diabetes, as this medicine may affect blood sugar control.","Long-term use may reduce bone mineral density; discuss with your doctor.","Do not share this medicine with others, even if they have similar symptoms."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but you should consult your doctor before use, especially if the infant is premature or has health issues.
💊 Overdose Management
Overdose with this medicine is unlikely to cause serious harm. Symptoms may include nausea, vomiting, and vaginal bleeding. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, at the same time each day, with or without food. Do not change the dose or stop the medicine on your own, because sudden discontinuation can cause irregular bleeding. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as this medicine is not recommended during pregnancy. Tell your doctor about all other medicines, supplements, and herbal products you take, especially blood thinners, anticonvulsants, and rifampicin, because they can interact with this medicine. Avoid smoking while taking this medicine, as smoking increases the risk of blood clots. If you have a history of blood clots, liver disease, or breast cancer, this medicine may not be suitable for you. Use effective non-hormonal contraception if you are sexually active and do not wish to become pregnant, since this medicine is not a reliable contraceptive at this dose. Keep all follow-up appointments and report any unusual vaginal bleeding, severe headache, or leg pain promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly women using this medicine should be monitored for blood pressure, fluid retention, and signs of blood clots. The risk of these effects increases with age. The dose should be individualized, and regular follow-up is important.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, stop this medicine and consult your doctor. This medicine is not recommended during pregnancy and may harm the fetus. Use effective contraception while taking it if you do not wish to conceive.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may increase the risk of blood clots after surgery. Your doctor may advise you to stop it temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There is no direct interaction with dental anesthetics, but it is important for your dentist to know your complete medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but if you experience heavy vaginal bleeding or dizziness, avoid strenuous activities and consult your doctor. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or mood changes in some people. If you feel dizzy, avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work routine, but if side effects are bothersome, talk to your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as blood clots, severe allergic reaction, or liver problems, stop immediately and seek medical help. Your doctor will advise you on when and how to stop based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with a small increased risk of breast cancer and reduced bone mineral density. Regular monitoring of bone health and breast examinations are recommended. It should be used at the lowest effective dose for the shortest duration necessary. Discuss with your doctor if you need to use it for more than a few months.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Weight management, exercise, and stress reduction can help regulate menstrual cycles.
Evidence: Well-establishedNorethisterone or dydrogesterone may be alternatives if you cannot tolerate this medicine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. Inform your healthcare provider about all medicines you are taking before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and avoid extreme heat or cold. If crossing time zones, continue taking your dose at the same interval as prescribed, but consult your doctor for specific advice. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For inducing a period, bleeding usually occurs within 3 to 7 days after completing the course. For controlling heavy bleeding, improvement may be seen within the first cycle.
A: No, this medicine is contraindicated during pregnancy as it may harm the fetus. If you become pregnant, stop the medicine and contact your doctor immediately.
A: Some women may experience fluid retention and mild weight changes, but significant weight gain is not common. A healthy diet and exercise can help.
🤔 Common Patient Concerns
🔄 Substitutes for megestone 10 mg tablet
View AllAlternative brands with exact same active ingredient:
-
stayhappi medroxyprogesterone acetate 10mg tabletSarvagunaushdhi Pvt Ltd ₹30.00 45.1% CHEAPER
-
perlutal-m 10mg tabletBewell Labs Pvt Ltd ₹36.35 33.5% CHEAPER
-
medona 10mg tabletWest-Coast Pharmaceutical Works Ltd ₹37.50 31.4% CHEAPER
-
empeea 10mg tabletPfizer Ltd ₹40.29 26.3% CHEAPER
-
dubloc 10mg tabletDewcare Concept Pvt.Ltd. ₹40.31 26.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a contraceptive pill.
Fact: At this dose, it is not a reliable contraceptive. It is used for menstrual disorders, not for birth control. - Myth: It can be taken without a prescription.
Fact: This is a prescription-only medicine and must be used under medical supervision. - Myth: It causes immediate weight gain.
Fact: Weight changes are not universal and are usually due to fluid retention, not fat gain.
🔄 Alternative Options
Generic Alternatives
- Medroxyprogesterone acetate 10 mg tablet
Brand Alternatives
- Dubloc 10mg Tablet