maxcio-g tablet - Gabapentin (150mg) + Methylcobalamin (750mcg) medicine

Gabarich 150mg/750mcg Tablet: Complete Guide To Uses, Side Effects, And Safety

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🏭 Haustus Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 30, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate to well-established for gabapentin in neuropathic pain; methylcobalamin evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Oct 30, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden swelling of face, lips, or throat, or difficulty breathing
  • Severe rash with blisters or peeling skin
  • Unusual changes in mood, depression, or suicidal thoughts
  • Severe dizziness or fainting
  • Decreased urine output or swelling in legs
  • Severe abdominal pain radiating to the back
  • Muscle pain with dark urine
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is maxcio-g tablet used for?

This medicine is a combination of gabapentin and methylcobalamin used to treat neuropathic pain and support nerve health. It works by calming overactive nerves and providing vitamin B12 to repair nerve damage. It is taken orally, usually once or twice daily, as prescribed by a doctor.

  • Generic Name: Gabapentin (150mg) + Methylcobalamin (750mcg)
  • Manufacturer: Haustus Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 maxcio-g tablet के बारे में (Hindi Summary)

उपयोग: यह दवा गैबापेंटिन और मिथाइलकोबालामिन का संयोजन है, जिसका उपयोग नसों से जुड़े दर्द (न्यूरोपैथिक दर्द) के इलाज के लिए किया जाता है। यह मधुमेह के कारण होने वाले नसों के दर्द, दाद के बाद होने वाले दर्द, और विटामिन बी12 की कमी से जुड़ी नसों की समस्याओं में फायदेमंद है। यह दवा नसों को शांत करके दर्द कम करती है और नसों की मरम्मत में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, नींद आना, थकान, और अस्थिरता शामिल हैं। कुछ लोगों को मतली या पेट में हल्की परेशानी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, या मूड में अचानक बदलाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दवा की खुराक खुद से न बदलें और न ही अचानक बंद करें। इस दवा के साथ शराब का सेवन न करें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो अपने डॉक्टर को बताएं। गुर्दे की बीमारी होने पर डॉक्टर खुराक बदल सकते हैं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 maxcio-g tablet Uses & Benefits

[{"condition":"Diabetic peripheral neuropathy","description":"This medicine helps relieve burning, tingling, and shooting pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"It reduces persistent nerve pain that can occur after a shingles infection.","evidence":"Well-established"},{"condition":"Neuropathic pain of other origins","description":"It may be used for nerve pain due to spinal cord injury, multiple sclerosis, or other nerve disorders.","evidence":"Moderate"},{"condition":"Vitamin B12 deficiency with neurological symptoms","description":"Methylcobalamin component helps correct B12 deficiency and supports nerve health.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Fibromyalgia","description":"Sometimes prescribed to help with widespread pain and sleep disturbances, though evidence is mixed.","evidence":"Limited"},{"condition":"Restless legs syndrome","description":"May be used off-label to reduce symptoms, but not first-line.","evidence":"Limited"}]

Primary treatment for: Neuropathic pain

Also treats: Diabetic neuropathy, Postherpetic neuralgia, Vitamin B12 deficiency with neurological symptoms

📋 Drug Information

Generic Name(s)Gabapentin (150mg) + Methylcobalamin (750mcg)
Brand Namemaxcio-g tablet
ManufacturerHaustus Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime initially to minimize dizziness and drowsiness during the day.
2
Do not stop this medicine abruptly; taper the dose gradually under medical supervision.
3
Avoid alcohol completely while taking this medicine to prevent excessive sedation.
4
Inform your doctor if you have kidney problems, as dose adjustment may be necessary.
5
Monitor your mood and report any unusual changes or suicidal thoughts immediately.
6
Take antacids at least 2 hours apart from this medicine to avoid absorption issues.
7
Use caution while driving or operating machinery until you know how this medicine affects you.
8
Keep all follow-up appointments to monitor your response and kidney function.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning or tingling in hands and feet
This medicine is commonly prescribed for neuropathic pain.
Likely Use
✅
Shooting or stabbing nerve pain
This medicine helps reduce nerve-related pain.
Likely Use
❌
Ordinary headache
This medicine is not a primary headache reliever.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGabapentin is absorbed from the gastrointestinal tract via a saturable transport mechanism. Bioavailability is dose-dependent and decreases as the dose increases. Methylcobalamin is absorbed in the ileum, with intrinsic factor facilitating its uptake.
DistributionGabapentin distributes widely in the body, including the brain and cerebrospinal fluid. It does not bind significantly to plasma proteins. Methylcobalamin is transported in the blood bound to transcobalamin II and stored in the liver.
Protein BindingGabapentin is less than 3% bound to plasma proteins. Methylcobalamin binding is not established from the available information.
MetabolismGabapentin is not metabolized by the liver and is excreted unchanged by the kidneys. Methylcobalamin is metabolized in the liver and tissues to active coenzyme forms.
Half-LifeThe elimination half-life of gabapentin is approximately 5 to 7 hours in patients with normal kidney function. The half-life of methylcobalamin is not established from the available information.
ExcretionGabapentin is eliminated unchanged primarily through the kidneys by glomerular filtration. Methylcobalamin is excreted in bile and urine, with some enterohepatic circulation.
BioavailabilityThe bioavailability of gabapentin is approximately 60% at lower doses but decreases at higher doses due to saturable absorption. Bioavailability of methylcobalamin is not established from the available information.
Onset of ActionPain relief from gabapentin may begin within a few days, but full therapeutic effect may take several weeks. Methylcobalamin's effect on nerve health develops gradually over weeks to months.
Peak Plasma TimeGabapentin reaches peak plasma concentration in about 2 to 3 hours after oral administration. Peak plasma time for methylcobalamin is not established from the available information.
Duration of ActionThe pain-relieving effect of gabapentin lasts about 6 to 8 hours per dose. The duration of action of methylcobalamin is not established from the available information.

How It Works

Gabapentin works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the nervous system. This action reduces the release of excitatory neurotransmitters, which helps calm overactive nerve signals that cause neuropathic pain. Methylcobalamin is a coenzyme form of vitamin B12 that is essential for the maintenance and repair of myelin sheath, the protective covering around nerves. Together, they help reduce nerve pain and support nerve regeneration.

Mechanism Steps

1
Gabapentin binds to calcium channels: Gabapentin attaches to the alpha-2-delta subunit of voltage-gated calcium channels on nerve cells.
2
Reduced neurotransmitter release: This binding decreases the influx of calcium into nerve terminals, reducing the release of excitatory neurotransmitters like glutamate and substance P.
3
Calming of overactive nerves: As a result, abnormal nerve firing that causes neuropathic pain is suppressed.
4
Methylcobalamin supports myelin: Methylcobalamin assists in the synthesis of myelin, the protective sheath around nerves, aiding in nerve repair and proper conduction.
5
Combined effect: The two ingredients work together to reduce pain and improve nerve health.

💡 How to Take maxcio-g tablet

Strength: Tablet containing Gabapentin 150 mg and Methylcobalamin 750 mcg.

1Take this medicine orally with a glass of water.
2You can take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush, chew, or break it.
4Take it at the same time each day to maintain consistent levels.
5If you are taking antacids, take them at least 2 hours before or after this medicine.
6Do not stop taking this medicine suddenly without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily, or as directed by your doctor. The exact dose and frequency depend on your condition, response to treatment, and kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Take it at the same time each day for best results.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require a lower dose due to reduced kidney function. Your doctor will adjust the dose based on your renal function. Use with caution as the risk of dizziness, drowsiness, and falls is higher in this age group.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance 30-59 mL/min, the dose may be reduced. For creatinine clearance 15-29 mL/min, further reduction is needed. For patients on hemodialysis, additional doses may be required after dialysis. Consult your doctor for personalized dosing.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment as gabapentin is not metabolized by the liver. However, caution is advised in patients with both hepatic and renal impairment.
Maximum Daily DoseThe maximum daily dose of gabapentin is 3600 mg, but for this combination, the dose is determined by your doctor based on your condition. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Alcohol
Avoid
Increases drowsiness and dizziness.
Antacids
Separate by 2 hours
Reduces gabapentin absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of maxcio-g tablet

✅ Common Side Effects

Dizziness (Common (10-20%))
Avoid sudden movements. If persistent or severe, consult your doctor.
Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If it interferes with daily activities, talk to your doctor.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue is overwhelming, consult your doctor.
Nausea (Common (5-10%))
Take with food. If nausea persists, contact your doctor.
Unsteadiness (Common (5-10%))
Use caution when walking or climbing stairs. Report if it worsens.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling of face/lips/throat, or difficulty breathing.
Suicidal thoughts or mood changes (Rare (<0.1%))
Contact your doctor or a mental health professional immediately if you notice any unusual changes in mood or behaviour.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a painful rash with blisters or peeling skin.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor promptly.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising or bleeding to your doctor.
Pancreatitis
Seek medical attention if you experience severe abdominal pain radiating to the back.
Rhabdomyolysis
Report muscle pain, weakness, or dark urine immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Morphine Major
Alcohol Major
Antacids Moderate
Cimetidine Moderate
Oral contraceptives Moderate
Naproxen Minor
Hydrocodone Minor

🚨 Major Interactions

  • Morphine and other opioids
  • Alcohol

⚡ Moderate Interactions

  • Antacids containing aluminum or magnesium
  • Cimetidine
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol should be strictly avoided while taking this medicine because it can increase the sedative effects of gabapentin, leading to excessive drowsiness, dizziness, and impaired coordination. It may also worsen nerve pain and interfere with treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity or allergy to gabapentin or methylcobalamin","Severe renal impairment (dose adjustment required, not absolute contraindication)","Not for use in children under 12 years unless prescribed by a specialist"]

⚠️ Warnings & Precautions

["May cause dizziness and drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not stop this medicine abruptly as it may cause withdrawal symptoms such as anxiety, insomnia, and sweating.","Use with caution in elderly patients due to increased risk of falls and confusion.","Inform your doctor if you have kidney disease, as dose adjustment may be needed.","May increase the risk of suicidal thoughts; monitor mood closely.","Avoid alcohol while taking this medicine.","Do not take antacids within 2 hours of this medicine."]

🤱 Lactation Safety

Gabapentin is excreted in breast milk. It is not known whether methylcobalamin is excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose of this medicine may cause severe drowsiness, dizziness, double vision, slurred speech, and difficulty breathing. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases of gabapentin overdose.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness. Be cautious while driving or operating machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all other medicines, supplements, or herbal products you are taking, especially pain relievers, antidepressants, or anti-anxiety medicines. If you have kidney problems, your doctor may need to adjust your dose. Do not share this medicine with others, even if they have similar symptoms. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of dizziness, drowsiness, and falls. Dose adjustment may be needed based on kidney function. Regular monitoring of renal function is advised. Use with caution and consider fall prevention strategies.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Gabapentin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Methylcobalamin is generally considered safe. Your doctor may adjust your treatment plan.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and increase sedation. Your doctor may advise you to stop it temporarily before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may interact with certain dental anesthetics or sedatives. Your dentist may need to adjust medications used during the procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on nerves.
🥗
Engage in regular low-impact exercises like walking or swimming.
😴
Practice good posture to prevent nerve compression.
💧
Include foods rich in vitamin B12 such as eggs, fish, and dairy.
🧘
Get adequate sleep to support nerve health.
🌞
Manage stress through relaxation techniques like meditation.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or drowsiness. Avoid activities that require alertness, such as heavy lifting or high-intensity workouts, until you know how the medicine affects you. Gentle exercises like walking or yoga are generally safe. Stay hydrated during exercise.

🥗 Diet Recommendations

Include omega-3 rich foods like flaxseeds and walnuts.
Reduce processed and high-sugar foods.
Eat a balanced diet rich in fruits and vegetables.
Ensure adequate vitamin B12 intake through dairy, eggs, and fish.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how it affects you. Office work is generally safe, but take breaks if you feel dizzy. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or your condition improves, your doctor will guide you on tapering the dose gradually. Abrupt discontinuation can cause withdrawal symptoms such as anxiety, insomnia, and sweating.

📅 Long-Term Use Effects

Long-term use of this medicine may require periodic monitoring of kidney function and vitamin B12 levels. Gabapentin can cause dependence, and sudden withdrawal should be avoided. Some patients may experience continued drowsiness or dizziness. Regular follow-up with your doctor is essential to assess the benefit and adjust the dose. Methylcobalamin is generally safe for long-term use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Transcutaneous electrical nerve stimulation (TENS)

May provide additional pain relief for some patients.

Evidence: Moderate
Acupuncture

Some patients report benefit for neuropathic pain.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust your dosing schedule gradually in consultation with your doctor. Carry enough supply for the entire trip. Check customs regulations for controlled substances, as gabapentin may be regulated in some countries.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with diabetic neuropathy
He had been suffering from burning and tingling in his feet for over a year. His doctor prescribed this medicine. After 4 weeks, he noticed a significant reduction in burning sensation and improved sleep. He took it regularly with food and avoided alcohol. He also monitored his blood sugar levels.
💡 Lesson: Consistent use and lifestyle modifications like blood sugar control enhance the effectiveness of this medicine.
👤 A 60-year-old woman with postherpetic neuralgia
After a bout of shingles, she experienced severe shooting pain in her chest. This medicine was prescribed. She initially felt drowsy but it subsided after a week. She was advised not to drive during the initial days. After 6 weeks, her pain was much better and she could resume her daily activities.
💡 Lesson: Patience is key as the medicine takes time to work, and side effects like drowsiness often diminish with continued use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start noticing some relief within a few days, but full therapeutic effect may take several weeks. Continue taking it as prescribed.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop suddenly. Consult your doctor first, as abrupt discontinuation can cause withdrawal symptoms.

Q: Is this medicine a painkiller?

A: It is not a traditional painkiller. It specifically targets nerve pain and also supports nerve health.

Q: Can I take this medicine with other painkillers?

A: Inform your doctor about all medicines you take. Some combinations may increase side effects.

Q: Does this medicine cause weight gain?

A: Weight gain is not a common side effect, but some people may experience increased appetite. Monitor your weight and consult your doctor if concerned.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Will I gain weight on this medicine?
  • Is it safe during pregnancy?

🔄 Substitutes for maxcio-g tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a simple painkiller for any type of pain.
    Fact: This medicine is specifically for nerve pain and is not effective for ordinary headaches or muscle pain.
  • Myth: You can stop this medicine as soon as you feel better.
    Fact: Stopping suddenly can cause withdrawal symptoms. Always consult your doctor before stopping.
  • Myth: This medicine is addictive.
    Fact: Gabapentin has a low potential for abuse but can cause dependence. It should only be used under medical supervision.
  • Myth: Taking more than the prescribed dose will relieve pain faster.
    Fact: Taking more can increase side effects and does not provide faster relief. Always follow the prescribed dose.

🔄 Alternative Options

Generic Alternatives

  • Gabapentin 150 mg + Methylcobalamin 750 mcg tablet (various manufacturers)

Brand Alternatives

  • Gabarich 150mg/750mcg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Gabapentin + Methylcobalamin","composition":"Gabapentin 150 mg + Methylcobalamin 750 mcg","uses":"Neuropathic pain, B12 deficiency","notes":"Combination provides pain relief and nerve support."},{"medicine":"Pregabalin + Methylcobalamin","composition":"Pregabalin 75 mg + Methylcobalamin 750 mcg","uses":"Neuropathic pain, B12 deficiency","notes":"Pregabalin has similar mechanism but may have different side effect profile."},{"medicine":"Gabapentin alone","composition":"Gabapentin 300 mg","uses":"Neuropathic pain, epilepsy","notes":"Does not provide B12 supplementation."}]

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