maskofung cream - Amorolfine (0.25% w/w) medicine

Livafin Cream: Complete Guide to Uses, Side Effects, and Safety

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🏭 Encore Pharmaceuticals Inc. 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
🤰 Pregnancy Category Not established from the available information. This medicine should be used during pregnancy only if clearly needed and after consulting a doctor. Topical application is unlikely to cause systemic exposure, but caution is advised. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for skin fungal infections; moderate for nail infections.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of the face, lips, tongue, or throat, difficulty breathing, or severe rash.
  • Severe skin reaction: blistering, peeling, or sores at the application site.
  • Signs of infection spreading: increased redness, swelling, pain, or pus.
  • No improvement after completing the full course of treatment.
  • New symptoms such as fever, chills, or feeling unwell.
  • Yellowing of the skin or eyes (jaundice), though rare with topical use.

If experiencing severe symptoms, call emergency services immediately.

What is maskofung cream used for?

This medicine is a topical antifungal cream used to treat skin and nail fungal infections. It works by destroying the fungal cell membrane. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily. Complete the full course of treatment even if symptoms improve.

  • Generic Name: Amorolfine (0.25% w/w)
  • Manufacturer: Encore Pharmaceuticals Inc.
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 maskofung cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीफंगल क्रीम है जिसका उपयोग त्वचा और नाखूनों के फंगल संक्रमण के इलाज के लिए किया जाता है। यह एथलीट फुट, जॉक इच, दाद और नाखून फंगस जैसी समस्याओं में प्रभावी है। यह क्रीम फंगस की कोशिका भित्ति को नष्ट करके उसे मार देती है। इसे प्रभावित क्षेत्र पर पतली परत में लगाएं और डॉक्टर के बताए अनुसार पूरा कोर्स करें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। दुर्लभ मामलों में गंभीर एलर्जी प्रतिक्रिया हो सकती है, जैसे सूजन, गंभीर दाने या छाले। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल बाहरी त्वचा पर करें। इसे आंखों, मुंह, नाक या कान में न लगाएं। टूटी त्वचा या घाव पर न लगाएं। उपयोग से पहले और बाद में हाथ धोएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 maskofung cream Uses & Benefits

[{"condition":"Athlete's foot (tinea pedis)","description":"This medicine is applied to the affected skin to treat fungal infections between the toes and on the soles of the feet, relieving itching, burning, and cracking.","evidence":"Well-established"},{"condition":"Jock itch (tinea cruris)","description":"This medicine helps clear fungal infections in the groin area, reducing redness, itching, and discomfort.","evidence":"Well-established"},{"condition":"Ringworm (tinea corporis)","description":"This medicine is used to treat ring-shaped fungal rashes on the body, eliminating the infection and promoting skin healing.","evidence":"Well-established"},{"condition":"Fungal nail infection (onychomycosis)","description":"This medicine may be applied to affected nails to treat mild to moderate fungal nail infections, though it is often used in combination with oral antifungals for severe cases.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Cutaneous candidiasis","description":"This medicine may sometimes be used to treat skin infections caused by Candida yeast, although it is not the primary treatment.","evidence":"Limited"},{"condition":"Tinea versicolor","description":"This medicine may be used off-label for treating tinea versicolor, a fungal infection that causes patches of discolored skin.","evidence":"Limited"}]

Primary treatment for: Fungal skin infections

Also treats: Athlete's foot, Jock itch, Ringworm, Fungal nail infection

📋 Drug Information

Generic Name(s)Amorolfine (0.25% w/w)
Brand Namemaskofung cream
ManufacturerEncore Pharmaceuticals Inc.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntifungal Others
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use. Do not freeze.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine exactly as prescribed by your doctor. Do not use more or less of it or use it more often than directed.
2
Clean and dry the affected area before applying the cream. This helps the medicine work better.
3
Wash your hands thoroughly after applying the cream to avoid spreading the infection to other parts of your body.
4
Complete the full course of treatment even if your symptoms improve after a few days. Stopping early can allow the infection to return.
5
If you are treating a nail infection, be patient. It may take several months for the nail to grow out and look normal.
6
Avoid sharing towels, clothing, or shoes with others to prevent spreading the fungal infection.
7
If your symptoms do not improve within the expected time frame, or if they worsen, contact your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, red, scaly skin patches
This medicine is commonly prescribed for fungal skin infections.
Likely Use
✅
Cracked, peeling skin between toes
This medicine is effective for athlete's foot.
Likely Use
✅
Thick, discolored nails
This medicine may be used for fungal nail infections.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Painful, swollen joints
This medicine is not for joint pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information. This medicine is applied topically and is designed to act locally on the skin and nails. Systemic absorption is minimal when applied to intact skin.
DistributionNot established from the available information. After topical application, this medicine remains primarily in the skin and its appendages, with limited systemic distribution.
Protein BindingNot established from the available information.
MetabolismNot established from the available information. Any small amount absorbed is likely metabolized in the liver, but specific pathways are not well defined.
Half-LifeNot established from the available information.
ExcretionNot established from the available information. Any absorbed drug is likely excreted via urine and feces, but specific data are lacking.
BioavailabilityNot established from the available information. Systemic bioavailability after topical application is considered negligible.
Onset of ActionClinical improvement may be noticed within a few days of starting treatment, but complete resolution of the infection may take several weeks, depending on the type and severity of the infection.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe antifungal effect persists as long as the medicine is applied regularly. After discontinuation, the effect gradually wears off as the drug is cleared from the skin.

How It Works

This medicine works by inhibiting the enzyme delta-14 reductase and delta-7,8 isomerase, which are involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. Without adequate ergosterol, the fungal cell membrane becomes weakened and leaky, leading to leakage of cellular contents and ultimately cell death. This medicine is fungicidal against a broad spectrum of fungi, including dermatophytes and yeasts. It specifically targets fungal cells and has minimal effect on human cells because human cell membranes use cholesterol instead of ergosterol.

Mechanism Steps

1
Penetration into fungal cell: This medicine penetrates the fungal cell wall and reaches the cell membrane.
2
Inhibition of ergosterol synthesis: It inhibits key enzymes (delta-14 reductase and delta-7,8 isomerase) involved in the production of ergosterol, a critical component of the fungal cell membrane.
3
Membrane disruption: The lack of ergosterol weakens the fungal cell membrane, causing it to become leaky and lose its integrity.
4
Fungal cell death: The compromised membrane leads to leakage of cellular contents and ultimately death of the fungal cell.

💡 How to Take maskofung cream

Strength: Cream containing amorolfine 0.25% w/w.

1Wash your hands thoroughly before and after applying the cream, unless the hands are the treated area.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected skin or nail.
4Rub it in gently until it is absorbed.
5Do not cover the area with a bandage or dressing unless instructed by your doctor.
6Avoid contact with eyes, mouth, and other mucous membranes.
7Use this medicine at the same time(s) each day to help you remember.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area once or twice daily, as directed by your doctor. The duration of treatment depends on the type and severity of the infection. For skin infections, treatment is usually continued for 2-4 weeks. For nail infections, treatment may be required for several months. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, they should use this medicine with caution and under medical supervision.
Renal ImpairmentNo dosage adjustments are required for patients with renal impairment, as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustments are required for patients with hepatic impairment, as systemic absorption is minimal.
Maximum Daily DoseNot established from the available information. Use only as directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No food interactions
Not applicable
This medicine is applied topically and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of maskofung cream

✅ Common Side Effects

Application site burning (Common (1-10%))
This usually resolves on its own. If it persists or worsens, consult your doctor.
Application site itching (Common (1-10%))
Try not to scratch. If itching is severe or persistent, consult your doctor.
Application site redness (Common (1-10%))
This is usually temporary. If redness spreads or becomes painful, consult your doctor.
Application site irritation (Common (1-10%))
Discontinue use and consult your doctor if irritation is severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Severe skin reaction (e.g., blistering, peeling) (Rare (<0.1%))
Stop using this medicine and seek immediate medical attention if you notice severe blistering, peeling, or sores at the application site.

⚠️ Rare Side Effects

Contact dermatitis
Discontinue use and consult your doctor if you develop a rash, swelling, or severe irritation at the application site.
Skin discoloration
Consult your doctor if you notice any unusual skin discoloration.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to amorolfine or any other ingredients in the cream.","Do not use on broken skin, open wounds, or mucous membranes.","Do not use in the eyes or ears.","Not for oral or intravaginal use."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, ears, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.","Do not apply to large areas of skin or for prolonged periods without medical advice.","If symptoms persist or worsen after the recommended treatment period, consult a doctor.","Do not use this medicine to treat any condition other than the one for which it was prescribed.","Keep out of reach of children.","If you are pregnant or breastfeeding, consult your doctor before use.","Do not share this medicine with others, even if they have similar symptoms."]

🤱 Lactation Safety

Not established from the available information. It is not known whether this medicine passes into breast milk. However, since it is applied topically, systemic absorption is minimal. To be safe, avoid applying the cream to the breast area to prevent accidental ingestion by the infant. Consult your doctor before use while breastfeeding.

💊 Overdose Management

This medicine is for topical use. Overdose is unlikely. If accidental ingestion occurs, seek immediate medical attention or contact a poison control center. Symptoms of ingestion may include nausea, vomiting, or abdominal discomfort. If excessive amounts are applied to the skin, wipe off the excess and rinse with water. Consult a doctor if irritation occurs.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are allergic to amorolfine or any other medications. This medicine is for external use only; do not swallow it. Avoid contact with eyes, ears, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse immediately with plenty of water. Do not apply to broken skin or wounds. Wash your hands thoroughly before and after applying the cream, unless the hands are the treated area. Keep the affected area clean and dry. Do not cover the treated area with airtight dressings unless instructed by your doctor. If your symptoms do not improve after the recommended treatment period, or if they worsen, consult your doctor. Do not use this medicine for any condition other than the one it was prescribed for. Do not share this medicine with others. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Store at room temperature, away from direct sunlight and moisture.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients can use this medicine safely. However, they may be more prone to skin irritation. Monitor the application site for any unusual reactions and consult a doctor if needed.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical application is unlikely to cause harm, but it is best to seek medical advice to ensure the safety of both mother and baby.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine on or near the surgical site. Avoid applying it to healing wounds unless instructed by your doctor.

🦷 Dental Procedures

This medicine is for topical use on the skin and nails. It is not used in the mouth and does not affect dental procedures. However, inform your dentist about all medications you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep your skin clean and dry, especially in skin folds.
🥗
Wear loose-fitting, breathable clothing to reduce moisture.
😴
Avoid sharing towels, socks, or shoes with others.
💧
Change your socks and underwear daily.
🧘
Use antifungal powder in shoes if you have athlete's foot.
🌞
Avoid walking barefoot in public places like locker rooms and pools.
🚭
Maintain a healthy diet and stay hydrated to support your immune system.

🏋️ Exercise Considerations

There are no specific exercise restrictions while using this medicine. However, if you have a fungal infection on your feet, avoid activities that cause excessive sweating or friction, as this may worsen the condition. Keep the affected area clean and dry after exercise.

🥗 Diet Recommendations

Include foods rich in probiotics, such as yogurt, to support a healthy immune system.
Limit sugary and processed foods, which may promote fungal growth.
Eat plenty of fruits and vegetables rich in vitamins and antioxidants.
Stay well hydrated by drinking plenty of water.
Include garlic, which has natural antifungal properties, in your diet.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. You can continue your normal daily activities. However, if you experience any side effects like severe irritation or allergic reaction, avoid driving or operating machinery until you feel better.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms do not improve after the recommended treatment period, if they worsen, or if you experience any severe side effects such as a severe allergic reaction or skin blistering. Do not stop treatment early for nail infections, as the infection may return. Always follow your doctor's advice on the duration of treatment.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when applied as directed. However, prolonged use over large areas of skin may increase the risk of local irritation or allergic reactions. If you are using it for a nail infection, treatment may last for several months. Regular monitoring by your doctor is recommended to assess the progress of the infection and to check for any adverse effects. If you notice any unusual skin changes, consult your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Good hygiene practices

Keeping the skin clean and dry, and avoiding sharing personal items, can help prevent fungal infections.

Evidence: Well-established
Tea tree oil

Some studies suggest tea tree oil has antifungal properties and may help with mild fungal infections, but evidence is limited.

Evidence: Limited
Oral antifungal medications

For severe or resistant infections, oral antifungals may be prescribed by a doctor.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in its original packaging with the prescription label intact. Carry a copy of your prescription in case you need to show it at customs or to a healthcare provider. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. If you are crossing time zones, continue applying the cream at your usual times; there is no need to adjust the schedule. Keep the tube tightly closed and protect it from direct sunlight. If you are traveling to a humid climate, ensure the cream is stored in a cool, dry place.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with athlete's foot
Raj had been suffering from itchy, cracked skin between his toes for weeks. His doctor prescribed this medicine to be applied twice daily. After two weeks of consistent use, his symptoms improved significantly. He made sure to dry his feet thoroughly after showering and wore clean socks daily.
💡 Lesson: Consistent application and good foot hygiene are key to treating athlete's foot effectively.
👤 A 50-year-old woman with a fungal nail infection
Meera noticed her toenail becoming thick and discolored. Her doctor recommended this medicine to be applied to the affected nail once daily. She diligently applied it for several months. Gradually, the healthy nail grew out, and the infection cleared. She was advised to continue until the nail fully grew out.
💡 Lesson: Nail fungal infections require long-term treatment and patience. Do not stop early even if you see improvement.

💬 Questions Patients Often Ask

Q: How long does it take for this medicine to work?

A: You may start to see improvement in skin infections within a few days to a week. However, it is important to complete the full course of treatment as prescribed, which may be 2-4 weeks for skin infections and several months for nail infections.

Q: Can I use this medicine on my face?

A: This medicine is generally not recommended for use on the face unless specifically prescribed by your doctor. The skin on the face is more sensitive and may be more prone to irritation. Consult your doctor before applying it to the face.

Q: Is this medicine safe for children?

A: The safety and effectiveness of this medicine in children have not been fully established. Consult a pediatrician before using it on a child.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.

Q: Can I use this medicine while pregnant?

A: Consult your doctor before using this medicine during pregnancy. Topical application is unlikely to cause harm, but it is best to seek medical advice.

Q: Does this medicine interact with other medications?

A: This medicine is applied topically and has minimal systemic absorption, so interactions with other medications are unlikely. However, inform your doctor about all medications you are taking.

Q: How should I store this medicine?

A: Store at room temperature (15-30°C), away from direct sunlight and moisture. Keep the tube tightly closed when not in use.

Q: Can I use this medicine for nail fungus?

A: Yes, this medicine can be used for fungal nail infections, but it may need to be applied for several months. Follow your doctor's instructions carefully.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long does it take to cure a fungal infection?
  • Is it safe to use this medicine every day?
  • Can I use this medicine if I have diabetes?
  • Will this medicine interact with my other medications?
  • What should I do if I accidentally swallow this cream?
  • Can I use this medicine on my child?
  • Does this medicine stain clothes?

🔄 Substitutes for maskofung cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any skin infection.
    Fact: This medicine is specifically for fungal infections. It is not effective against bacterial or viral skin infections.
  • Myth: You can stop using this medicine as soon as symptoms improve.
    Fact: It is important to complete the full course of treatment to prevent the infection from returning.
  • Myth: This medicine works instantly.
    Fact: It may take several days to weeks to see improvement, depending on the type and severity of the infection.
  • Myth: This medicine is safe to use on any part of the body.
    Fact: It should not be used on broken skin, mucous membranes, or near the eyes. Follow your doctor's instructions.

🔄 Alternative Options

Generic Alternatives

  • Amorolfine 0.25% w/w cream

Brand Alternatives

  • Loceryl
  • Amorolfine cream
  • Funginil
  • Mycofin

📊 Comparison with Similar Medicines

[{"medicine":"Amorolfine cream","class":"Morpholine antifungal","primary_use":"Skin and nail fungal infections","route":"Topical","frequency":"Once or twice daily"},{"medicine":"Clotrimazole cream","class":"Imidazole antifungal","primary_use":"Skin fungal infections","route":"Topical","frequency":"Twice daily"},{"medicine":"Terbinafine cream","class":"Allylamine antifungal","primary_use":"Skin fungal infections","route":"Topical","frequency":"Once or twice daily"}]

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