Levetiracetam 1000 Mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Seek immediate medical help if you develop a rash, blisters, or peeling skin.
- Go to the emergency room if you have swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Contact your doctor right away if you have thoughts of harming yourself or others.
- Seek immediate care if you experience severe dizziness, loss of coordination, or double vision.
- Report any signs of infection such as fever, sore throat, or unusual bleeding or bruising to your doctor immediately.
- If you have a seizure that lasts longer than 5 minutes or you have multiple seizures in a row, call emergency services.
If experiencing severe symptoms, call emergency services immediately.
What is manotam 1000mg tablet used for?
This medicine contains Levetiracetam 1000 mg, an antiepileptic drug used to treat partial-onset, myoclonic, and primary generalized tonic-clonic seizures. It works by binding to SV2A protein in the brain to reduce abnormal electrical activity. It is taken orally, usually twice daily, and dose must be individualized by a doctor.
- Generic Name: Levetiracetam (1000mg)
- Manufacturer: Cmg Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 manotam 1000mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवेटिरासेटम 1000 मिलीग्राम की एक गोली है, जिसका उपयोग मिर्गी के दौरे के इलाज के लिए किया जाता है। यह आंशिक दौरे, मायोक्लोनिक दौरे और प्राइमरी जनरलाइज्ड टॉनिक-क्लोनिक दौरे को नियंत्रित करने में मदद करती है। यह मस्तिष्क में एक प्रोटीन से बंधकर दौरे की गतिविधि को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, थकान, चक्कर आना और कमजोरी शामिल हैं। कुछ लोगों में चिड़चिड़ापन, चिंता या व्यवहार में बदलाव भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको त्वचा पर दाने, सूजन, सांस लेने में कठिनाई, या आत्म-नुकसान के विचार आते हैं, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इसे डॉक्टर के बताए अनुसार ही लें, अपने आप मात्रा न बदलें और न ही अचानक बंद करें। दवा लेते समय शराब न पिएं और वाहन चलाने से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।
💊 manotam 1000mg tablet Uses & Benefits
[{"condition":"Partial-onset seizures","description":"Used as adjunctive therapy in the treatment of partial-onset seizures in adults and children 4 years and older with epilepsy.","evidence":"Well-established"},{"condition":"Myoclonic seizures","description":"Indicated as adjunctive therapy in the treatment of myoclonic seizures in adults and adolescents 12 years of age and older with juvenile myoclonic epilepsy.","evidence":"Well-established"},{"condition":"Primary generalized tonic-clonic seizures","description":"Indicated as adjunctive therapy in the treatment of primary generalized tonic-clonic seizures in adults and children 6 years of age and older with idiopathic generalized epilepsy.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Status epilepticus","description":"Sometimes used off-label in the management of status epilepticus, a medical emergency involving prolonged seizures.","evidence":"Limited"},{"condition":"Neuropathic pain","description":"Occasionally prescribed off-label for neuropathic pain, although evidence is limited and it is not a first-line treatment.","evidence":"Limited"},{"condition":"Tardive dyskinesia","description":"Rarely used off-label for tardive dyskinesia, a movement disorder caused by certain psychiatric medications.","evidence":"Limited"}]
Primary treatment for: Epilepsy
Also treats: Partial-onset seizures, Myoclonic seizures, Primary generalized tonic-clonic seizures
📋 Drug Information
| Generic Name(s) | Levetiracetam (1000mg) |
| Brand Name | manotam 1000mg tablet |
| Manufacturer | Cmg Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Synaptic vescicle 2 A protein ligand (AED) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to a specific protein in the brain called synaptic vesicle protein 2A (SV2A). This binding modulates the release of neurotransmitters, which are chemicals that transmit signals between nerve cells. By affecting neurotransmitter release, this medicine helps to stabilize electrical activity in the brain and reduce the spread of seizure activity. Unlike some other antiepileptic drugs, this medicine does not appear to act primarily through sodium channels, GABA receptors, or glutamate receptors. Its unique mechanism makes it effective for certain types of seizures that may not respond to other treatments.
Mechanism Steps
💡 How to Take manotam 1000mg tablet
Strength: Levetiracetam 1000 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for partial-onset seizures, myoclonic seizures, and primary generalized tonic-clonic seizures is 1000 mg to 3000 mg per day, divided into two doses. The starting dose is typically 500 mg twice daily, and the dose may be increased by 500 mg twice daily every 2 to 4 weeks until the desired effect is achieved. The maximum recommended dose is 3000 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require a lower dose due to reduced renal function. Dose should be adjusted based on creatinine clearance. Consult a doctor for individualized dosing. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For patients with creatinine clearance 50-80 mL/min, the dose is 500-1000 mg every 12 hours. For creatinine clearance 30-50 mL/min, the dose is 250-750 mg every 12 hours. For creatinine clearance less than 30 mL/min, the dose is 250-500 mg every 12 hours. For patients on dialysis, a supplemental dose of 250-500 mg is recommended after dialysis. Consult a doctor for precise dosing. |
| Hepatic Impairment | No dose adjustment is needed for patients with mild to moderate hepatic impairment. For patients with severe hepatic impairment, dose should be adjusted based on renal function. Consult a doctor. |
| Maximum Daily Dose | 3000 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of manotam 1000mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | |
| Carbamazepine | Moderate | |
| CNS depressants | Moderate | |
| Rifampicin | Moderate | |
| Warfarin | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Methotrexate
- Carbamazepine
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Rifampicin
🍷 Alcohol Interaction
Alcohol can increase the drowsiness and dizziness caused by this medicine. It is recommended to avoid alcohol while taking this medicine, as it can also increase the risk of seizures.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levetiracetam or any component of the formulation","Severe renal impairment (creatinine clearance less than 30 mL/min) without dose adjustment"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness, dizziness, and fatigue. Avoid driving or operating machinery until you know how it affects you.","Do not stop taking this medicine abruptly, as it can cause withdrawal seizures. Taper gradually under medical supervision.","This medicine may cause serious skin reactions. Seek immediate medical attention if you develop a rash, blisters, or peeling skin.","This medicine may increase the risk of suicidal thoughts or behavior. Monitor for changes in mood or behavior.","This medicine can cause serious allergic reactions. Seek emergency help if you experience swelling of the face, lips, or throat, or difficulty breathing.","Use with caution in patients with renal impairment. Dose adjustment may be needed.","Use with caution in elderly patients due to increased risk of side effects and reduced renal function.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, agitation, aggression, respiratory depression, and coma. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote for levetiracetam overdose. Hemodialysis may be effective in removing levetiracetam from the blood in cases of severe overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have kidney problems, liver problems, or a history of depression or mental illness. This medicine can cause drowsiness and dizziness, so avoid driving or operating heavy machinery until you know how it affects you. Do not drink alcohol while taking this medicine, as it can increase drowsiness and dizziness. Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor, as sudden withdrawal can cause seizures to worsen. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and heat. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor about the risks and benefits of this medicine. This medicine may interact with other medicines, so always inform your doctor about all the medicines you are taking, including over-the-counter products and herbal supplements. Regular follow-up with your doctor is important to monitor your response to treatment and adjust the dose if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Dose adjustment may be needed based on kidney function. Regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before conception. This medicine should be used during pregnancy only if the potential benefit justifies the risk. Your doctor may adjust your dose or switch to another medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents. Your doctor will manage your dose around the time of surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may interact with certain dental anesthetics or medications. Your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine, but you should avoid activities that could be dangerous if you experience drowsiness or dizziness, such as swimming alone or cycling on busy roads. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also affect your concentration and mood, so discuss any concerns with your employer if needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your seizures are well-controlled, your doctor may consider gradually reducing the dose. Abrupt withdrawal can cause seizures to worsen.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. However, regular monitoring of kidney function, blood counts, and mood is recommended. Some patients may experience persistent drowsiness or behavioral changes. The dose may need adjustment over time based on your response and any side effects. It is important to attend regular follow-up appointments with your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A high-fat, low-carbohydrate diet that may help reduce seizures in some patients, especially children.
Evidence: Well-established for certain types of epilepsyA device implanted under the skin that sends electrical signals to the vagus nerve to reduce seizures.
Evidence: Well-established for refractory epilepsySurgical removal of the brain area causing seizures, considered for some patients with drug-resistant epilepsy.
Evidence: Well-established for selected patients💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. If you are crossing time zones, consult your doctor about how to adjust your dosing schedule. Store the medicine at room temperature and avoid leaving it in hot or humid places, such as a car. Check the customs regulations of your destination regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but it may take several weeks to achieve full seizure control. Your doctor will adjust the dose gradually to find the most effective dose for you.
A: This medicine can interact with some other medications. Always inform your doctor about all the medicines you are taking, including over-the-counter drugs and herbal supplements.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine should be used during pregnancy only if the potential benefit justifies the risk. Consult your doctor if you are pregnant or planning to become pregnant.
A: No, do not stop taking this medicine without consulting your doctor. Stopping suddenly can cause seizures to return or worsen.
🤔 Common Patient Concerns
🔄 Substitutes for manotam 1000mg tablet
View AllAlternative brands with exact same active ingredient:
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davaindia levetiracetam 1000mg tabletDavaindia Generic Pharmacy ₹130.00 35% CHEAPER
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levecon-sr 1000 tabletConsern Pharma Limited ₹153.19 23.4% CHEAPER
-
epilive premix 1000mg injectionLupin Ltd ₹188.86 5.6% CHEAPER
-
leverise 1000mg tabletCarise Pharmaceuticals Pvt Ltd ₹192.19 3.9% CHEAPER
-
levipra 1000mg tabletEvaxo Pharma ₹193.13 3.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a cure for epilepsy.
Fact: This medicine helps control seizures but does not cure epilepsy. It must be taken regularly to prevent seizures. - Myth: You can stop taking this medicine once seizures are controlled.
Fact: Stopping this medicine suddenly can cause seizures to return or worsen. Always consult your doctor before stopping. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine should be used during pregnancy only if the potential benefit justifies the risk. Consult your doctor. - Myth: This medicine causes memory loss.
Fact: Some people may experience memory problems, but it is not a common side effect. Consult your doctor if you have concerns.
🔄 Alternative Options
Generic Alternatives
- Levetiracetam 1000 mg tablet
Brand Alternatives
- Not established from the available information.