Liofen 10 Tablet (Baclofen 10mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Sudden onset of severe drowsiness or difficulty staying awake.
- Confusion, hallucinations, or unusual behavior.
- Seizures or convulsions.
- Difficulty breathing or shortness of breath.
- Severe dizziness or fainting.
- Signs of a severe allergic reaction such as swelling of the face, lips, or throat, or a widespread rash.
- Inability to urinate or severe pain in the lower abdomen.
If experiencing severe symptoms, call emergency services immediately.
What is liswas 10mg tablet er used for?
This medicine contains Baclofen 10 mg, a muscle relaxant used to treat muscle spasticity caused by conditions like multiple sclerosis, spinal cord injury, and cerebral palsy. It works by acting on GABA-B receptors in the spinal cord to reduce muscle stiffness and spasms. It is available only by prescription and should be taken exactly as directed.
- Generic Name: Baclofen (10mg)
- Manufacturer: Dycine Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 liswas 10mg tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा बैक्लोफेन 10 मिलीग्राम युक्त एक मसल रिलैक्सेंट है, जिसका उपयोग मांसपेशियों की अकड़न और ऐंठन के इलाज के लिए किया जाता है। यह मल्टीपल स्क्लेरोसिस, रीढ़ की हड्डी की चोट और सेरेब्रल पाल्सी जैसी स्थितियों में मांसपेशियों की जकड़न को कम करने में मदद करती है। यह दवा मांसपेशियों को आराम देकर हिलने-डुलने में सुधार करती है और दर्द को कम करती है। यह केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर के बताए अनुसार ही लेना चाहिए। इसे अचानक बंद नहीं करना चाहिए, क्योंकि इससे गंभीर लक्षण हो सकते हैं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, कमजोरी, थकान और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें अत्यधिक नींद, भ्रम, मतिभ्रम, सांस लेने में कठिनाई और दौरे पड़ सकते हैं। यदि आपको कोई भी गंभीर या लगातार बना रहने वाला दुष्प्रभाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दवा की खुराक को बदलें या अचानक बंद न करें, क्योंकि इससे गंभीर प्रतिक्रियाएँ हो सकती हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या भारी मशीनरी चलाने से बचें। इस दवा के साथ शराब का सेवन न करें। यदि आपको गुर्दे या यकृत की बीमारी है या दौरे पड़ने का इतिहास है, तो अपने डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें।
💊 liswas 10mg tablet er Uses & Benefits
[{"condition":"Spasticity associated with multiple sclerosis","description":"This medicine helps reduce muscle stiffness and spasms, improving mobility and comfort in patients with multiple sclerosis.","evidence":"Well-established"},{"condition":"Spasticity due to spinal cord injury","description":"It is used to manage severe muscle spasticity and spasms following spinal cord injury, aiding in rehabilitation.","evidence":"Well-established"},{"condition":"Spasticity in cerebral palsy","description":"In certain cases, this medicine may be prescribed to reduce spasticity in patients with cerebral palsy, though use is often individualized.","evidence":"Moderate"},{"condition":"Muscle spasms of various origins","description":"It can be used to relieve painful muscle spasms caused by other neurological disorders.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Alcohol withdrawal syndrome","description":"Sometimes prescribed off-label to manage symptoms of alcohol withdrawal, but this is not a standard first-line treatment.","evidence":"Limited"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Baclofen may be used off-label to reduce reflux episodes by relaxing the lower esophageal sphincter.","evidence":"Limited"},{"condition":"Trigeminal neuralgia","description":"Rarely used off-label for trigeminal neuralgia pain, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Spasticity
Also treats: Multiple sclerosis, Spinal cord injury, Cerebral palsy
📋 Drug Information
| Generic Name(s) | Baclofen (10mg) |
| Brand Name | liswas 10mg tablet er |
| Manufacturer | Dycine Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Skeletal muscle relaxant- Centrally acting |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container, tightly closed. Do not refrigerate unless specified by the manufacturer. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the package before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by acting as an agonist at gamma-aminobutyric acid type B (GABA-B) receptors in the spinal cord. By mimicking the inhibitory neurotransmitter GABA, it reduces the release of excitatory neurotransmitters from sensory neurons, thereby decreasing muscle tone and spasticity. This central action helps suppress abnormal reflex activity that leads to muscle stiffness and spasms.
Mechanism Steps
💡 How to Take liswas 10mg tablet er
Strength: Baclofen 10 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults is 5 mg three times daily, which may be gradually increased by your doctor based on your response and tolerance. The dose may be increased every 3 days by 5 mg increments up to a maximum of 80 mg per day (20 mg four times daily) for spasticity. For other indications, doses may vary. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness and dizziness. Doses should be started low and increased slowly. Renal function should be assessed before and during treatment, as age-related decline in kidney function can lead to accumulation. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine should be reduced. For mild to moderate renal impairment, a lower starting dose and slower titration are recommended. In severe renal impairment (creatinine clearance < 30 mL/min), use is contraindicated or should be avoided. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | No specific dosage adjustments are provided for hepatic impairment in the manufacturer's labeling. However, because baclofen is minimally metabolized by the liver, significant hepatic impairment is unlikely to require dose adjustment. Use with caution and monitor for side effects. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose for spasticity is 80 mg per day, but in some cases, higher doses may be used under close medical supervision. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of liswas 10mg tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioids | Major | |
| Benzodiazepines | Major | |
| Tricyclic antidepressants | Major | |
| MAOIs | Major | |
| Antihypertensives | Moderate | |
| Lithium | Moderate | |
| Levodopa | Moderate | |
| Antacids | Minor | |
| Diuretics | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- CNS depressants (e.g., opioids, benzodiazepines, alcohol)
- Tricyclic antidepressants (e.g., amitriptyline)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Antihypertensive drugs
- Lithium
- Levodopa
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both alcohol and baclofen depress the central nervous system, and their combined use can lead to excessive sedation, drowsiness, dizziness, respiratory depression, and impaired motor skills. This can increase the risk of accidents and falls. If you consume alcohol, discuss it with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to baclofen or any component of the formulation.","Severe renal impairment (e.g., end-stage renal disease) due to risk of accumulation and toxicity.","Use in patients with a history of seizures is not an absolute contraindication but requires caution."]
⚠️ Warnings & Precautions
["Abrupt withdrawal of baclofen can cause serious reactions including hallucinations, seizures, and rebound spasticity. Taper gradually under medical supervision.","May cause drowsiness, dizziness, and sedation. Avoid driving or operating machinery until you know how it affects you.","Use with caution in elderly patients due to increased risk of sedation and renal impairment.","Use with caution in patients with psychiatric disorders, as it may worsen symptoms.","May cause respiratory depression, especially in patients with underlying respiratory disease or when used with other CNS depressants.","Use with caution in patients with renal impairment; dose adjustment is required.","May affect blood sugar levels in diabetic patients; monitor glucose."]
🤱 Lactation Safety
Baclofen is excreted in human breast milk in small amounts. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine can cause symptoms such as severe drowsiness, confusion, hallucinations, respiratory depression, seizures, and coma. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Maintain airway, breathing, and circulation. Monitor vital signs and provide supportive care. Hemodialysis may be considered in severe cases, especially in patients with renal failure.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor, as sudden withdrawal can cause serious reactions. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Avoid drinking alcohol while taking this medicine, as it can increase drowsiness and other central nervous system effects. Inform your doctor if you have kidney disease, liver disease, or a history of seizures, as dose adjustments may be needed. Do not use this medicine if you are pregnant or planning to become pregnant without consulting your doctor. If you are breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience side effects such as drowsiness, dizziness, and confusion. They may also have reduced renal function, which can lead to accumulation of the medicine. Doses should be started low and increased slowly. Regular monitoring of renal function and mental status is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. Baclofen is classified as Pregnancy Category C, meaning risk to the fetus cannot be ruled out. Your doctor will weigh the benefits and risks. Effective contraception should be used during treatment if pregnancy is not desired.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and other medications used during surgery. Your doctor may advise you to temporarily stop the medicine or adjust the dose. Do not stop it on your own.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with sedatives or anesthetics used during dental work. Your dentist may need to adjust medications or take precautions. Do not stop taking this medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience drowsiness and dizziness, which can affect your coordination. Avoid activities that require mental alertness, such as driving or operating machinery, until you know how the medicine affects you. Exercise should be performed with caution, and you should stop if you feel dizzy or weak. Physical therapy can be beneficial but should be done under professional guidance.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to perform certain tasks at work, especially those requiring alertness or coordination. It is important to discuss your job responsibilities with your doctor. You may need to avoid driving or operating heavy machinery until you know how the medicine affects you. Flexible work arrangements or temporary modifications may be necessary.
🛑 When to Stop This Medicine
You should not stop taking this medicine without consulting your doctor. Your doctor will determine when and how to stop based on your condition and response to treatment. If you experience severe side effects or your condition worsens, contact your doctor immediately. Abrupt discontinuation can cause withdrawal symptoms, so the dose is usually tapered gradually.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, requiring dose adjustments. It can also cause dependence, and abrupt withdrawal can be dangerous. Regular monitoring of renal function is important, especially in elderly patients. Some patients may experience persistent drowsiness or weakness. Your doctor will periodically assess the benefits and risks of continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and spasticity.
Evidence: Well-establishedHelps improve daily functioning and adapt to spasticity.
Evidence: Well-establishedMay be used for focal spasticity in certain muscle groups.
Evidence: Well-establishedConsidered for severe, refractory spasticity in selected patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor that you are taking this medicine. Generally, inactivated vaccines can be given safely.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, consult your doctor about how to adjust your dosing schedule. Check the laws of your destination country regarding prescription medicines. Always carry enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 1 to 2 hours after taking a dose. However, the full benefits for spasticity may take several days to weeks as your dose is adjusted.
A: No, you should never stop this medicine suddenly. Doing so can cause serious withdrawal symptoms such as hallucinations, seizures, and rebound spasticity. Always consult your doctor before stopping.
A: Taking this medicine with other muscle relaxants or CNS depressants can increase sedation and other side effects. Consult your doctor before combining.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of respiratory depression.
🤔 Common Patient Concerns
🔄 Substitutes for liswas 10mg tablet er
View AllAlternative brands with exact same active ingredient:
-
davaindia baclofen 10mg tabletDavaindia Generic Pharmacy ₹15.00 89.4% CHEAPER
-
stayhappi baclofen 10mg tabletSarvagunaushdhi Pvt Ltd ₹33.00 76.8% CHEAPER
-
Tefsole 10mg TabletVhb Life Sciences Inc ₹54.00 62% CHEAPER
-
Rowmax 10mg TabletRowlinges Life Science ₹60.00 57.7% CHEAPER
-
spinobak 10 tabletMankind Pharma Ltd ₹64.70 54.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is a muscle relaxant, not a general painkiller. It specifically targets muscle spasticity and does not relieve all types of pain. - Myth: You can stop this medicine whenever you feel better.
Fact: You should never stop this medicine suddenly, as it can cause serious withdrawal symptoms. Always consult your doctor before stopping. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided while taking this medicine because it can increase drowsiness and other central nervous system effects. - Myth: This medicine is addictive.
Fact: This medicine is not considered addictive in the traditional sense, but it can cause dependence and withdrawal if stopped abruptly.
🔄 Alternative Options
Generic Alternatives
- Baclofen 10 mg tablet
Brand Alternatives
- Liofen 10 Tablet
- Baclof 10 Tablet
- Baclon 10 Tablet