Lenangio 10 Capsule (Lenalidomide 10 mg): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fever, chills, or sore throat that may indicate a serious infection.
- Sudden shortness of breath, chest pain, or coughing up blood.
- Swelling, pain, or redness in one leg or arm.
- Severe headache, confusion, or vision changes.
- Unusual bleeding or bruising, such as nosebleeds or blood in stool.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Decreased urine output or swelling in the face, hands, or feet.
- Severe skin rash with blisters or peeling.
If experiencing severe symptoms, call emergency services immediately.
What is lenated 10mg capsule used for?
This medicine is a prescription oral capsule containing lenalidomide 10 mg. It is used to treat multiple myeloma, myelodysplastic syndromes with deletion 5q, and mantle cell lymphoma. It works by modulating the immune system and inhibiting tumor cell growth. It is contraindicated in pregnancy and requires strict monitoring.
- Generic Name: Lenalidomide (10mg)
- Manufacturer: Therdose Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lenated 10mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा लेनालिडोमाइड 10 मिलीग्राम कैप्सूल के रूप में उपलब्ध है और यह मल्टीपल मायलोमा, मायलोडिस्प्लास्टिक सिंड्रोम (विशेषकर 5q डिलीशन वाले), और मेंटल सेल लिंफोमा के इलाज के लिए इस्तेमाल की जाती है। यह कैंसर कोशिकाओं की वृद्धि को रोकती है और शरीर की प्रतिरक्षा प्रणाली को मजबूत करती है। यह दवा केवल कैंसर विशेषज्ञ की देखरेख में ही ली जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, कमजोरी, दस्त, जी मिचलाना, कब्ज, दाने, और हाथ-पैरों में झुनझुनी शामिल हैं। गंभीर दुष्प्रभावों में रक्त के थक्के बनना, संक्रमण का खतरा बढ़ना, खून की कमी, और लीवर की समस्या हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा गर्भावस्था में बेहद खतरनाक है और जन्मजात विकृतियां पैदा कर सकती है। महिलाओं और पुरुषों दोनों को सख्त गर्भनिरोधक उपाय अपनाने चाहिए। इलाज के दौरान रक्त की नियमित जांच करवाएं। संक्रमण से बचने के लिए हाथ धोते रहें और भीड़-भाड़ से दूर रहें। दवा को डॉक्टर की सलाह के बिना बंद न करें।
💊 lenated 10mg capsule Uses & Benefits
[{"condition":"Multiple myeloma","description":"Used in combination with dexamethasone or other agents for the treatment of newly diagnosed or previously treated multiple myeloma in adults.","evidence":"Well-established"},{"condition":"Myelodysplastic syndromes with deletion 5q","description":"Indicated for transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes associated with a deletion 5q abnormality.","evidence":"Well-established"},{"condition":"Mantle cell lymphoma","description":"Indicated for patients with mantle cell lymphoma whose disease has relapsed or progressed after two prior therapies, one of which included bortezomib.","evidence":"Well-established"},{"condition":"Follicular lymphoma","description":"Used in combination with rituximab for previously treated follicular lymphoma.","evidence":"Emerging"}]
Off-label uses: [{"condition":"AL amyloidosis","description":"Sometimes used off-label in combination regimens for light chain amyloidosis.","evidence":"Limited"},{"condition":"Cutaneous lupus erythematosus","description":"Occasionally used off-label for severe skin lupus not responding to standard treatments.","evidence":"Limited"},{"condition":"Myelofibrosis","description":"Investigated off-label for anemia in myelofibrosis, but evidence is not robust.","evidence":"Limited"}]
Primary treatment for: Multiple myeloma
Also treats: Myelodysplastic syndromes with deletion 5q, Mantle cell lymphoma
📋 Drug Information
| Generic Name(s) | Lenalidomide (10mg) |
| Brand Name | lenated 10mg capsule |
| Manufacturer | Therdose Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Thalidomide & its Immunomodulatory derivatives (IMiDs) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep in the original container, tightly closed, away from moisture and heat. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is an immunomodulatory agent that exerts its effects through multiple mechanisms. It binds to the protein cereblon, which is part of an E3 ubiquitin ligase complex. This binding leads to the degradation of specific transcription factors, such as Ikaros and Aiolos, which are important for the survival of myeloma cells. By promoting their breakdown, this medicine directly inhibits the growth and survival of malignant plasma cells. It also enhances the immune system's ability to attack cancer cells by stimulating T cells and natural killer cells, and it reduces the production of inflammatory cytokines like tumor necrosis factor-alpha. Additionally, it has anti-angiogenic properties, meaning it can inhibit the formation of new blood vessels that tumors need to grow. In myelodysplastic syndromes with deletion 5q, this medicine specifically targets the abnormal clone of cells, helping to restore normal blood cell production.
Mechanism Steps
💡 How to Take lenated 10mg capsule
Strength: Capsule, 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for multiple myeloma is 25 mg once daily on days 1 to 21 of a 28-day cycle, in combination with dexamethasone. For myelodysplastic syndromes with deletion 5q, the recommended dose is 10 mg once daily. For mantle cell lymphoma, the dose is 25 mg once daily on days 1 to 21 of a 28-day cycle. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and blood counts. Dose reductions may be necessary for side effects. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially blood clots, infections, and peripheral neuropathy. Dose selection should be cautious, and kidney function should be monitored closely. No specific dose adjustment is recommended based solely on age, but individualization is essential. |
| Renal Impairment | For patients with moderate renal impairment (creatinine clearance 30-60 mL/min), the dose may need to be reduced. For severe renal impairment (creatinine clearance less than 30 mL/min, not on dialysis), the dose should be reduced further. For patients on dialysis, the dose should be adjusted and administered after dialysis. Consult a specialist for precise dosing. |
| Hepatic Impairment | No specific dose adjustment is recommended for patients with mild to moderate hepatic impairment. However, this medicine should be used with caution in patients with severe hepatic impairment, as safety and efficacy have not been established. Monitor liver function closely. |
| Maximum Daily Dose | The maximum recommended daily dose is 25 mg for most indications, but may be higher in clinical trials. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lenated 10mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Dexamethasone | Major | |
| Warfarin | Major | |
| Erythropoietin | Major | |
| Digoxin | Moderate | |
| Statins | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Dexamethasone
- Erythropoietin
- Warfarin
⚡ Moderate Interactions
- Digoxin
- Statins
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and liver problems. It is best to avoid alcohol while taking this medicine, especially if you have liver disease or are taking other medicines that affect the liver.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or women who are planning to become pregnant.","Known hypersensitivity to lenalidomide or thalidomide.","Women of childbearing potential who are not using two reliable forms of contraception.","Men who are not using condoms during sexual contact with women of childbearing potential.","Breastfeeding.","Severe kidney impairment requiring dialysis (unless under specialist supervision)."]
⚠️ Warnings & Precautions
["This medicine can cause severe birth defects. Strict pregnancy prevention measures are mandatory for all patients.","Do not donate blood or sperm while taking this medicine and for at least 4 weeks after stopping.","This medicine can increase the risk of blood clots. Tell your doctor if you have a history of clots or are immobile for long periods.","This medicine can lower blood counts, increasing the risk of infection, anemia, and bleeding. Regular blood tests are essential.","Peripheral neuropathy may occur and can be irreversible. Report symptoms promptly.","This medicine may increase the risk of second cancers, including leukemia and lymphoma.","Do not share this medicine with anyone else, even if they have the same condition.","Keep all appointments with your healthcare team and follow their instructions carefully."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding is not recommended during treatment and for at least 4 weeks after stopping.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, seek immediate medical attention. Treatment should be supportive and symptomatic, with close monitoring of vital signs and blood counts. Dialysis may be considered in severe cases, but its effectiveness is not well established.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember if it is within 12 hours of the scheduled time. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
This medicine must only be taken under the supervision of a qualified cancer specialist. Because it can cause severe birth defects, women of childbearing potential must use two reliable forms of contraception, and men must use condoms during and for at least four weeks after stopping treatment. Pregnancy testing is required before starting and regularly during treatment. Do not donate blood or sperm while taking this medicine and for a period after stopping, as this could expose a pregnant woman to the drug. This medicine can make you more prone to infections, so wash your hands frequently, avoid crowds, and stay away from people who are sick. Report any signs of infection, such as fever, chills, or sore throat, right away. Blood clots are a risk, so tell your doctor if you notice swelling, pain, or redness in one leg, or sudden shortness of breath or chest pain. Do not stop taking this medicine without talking to your doctor first. Keep all appointments for blood tests and check-ups. Store this medicine at room temperature, away from moisture and heat, and keep it out of reach of children. Never share this medicine with anyone else, even if they have the same condition.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Patients over 65 years of age may be more susceptible to the side effects of this medicine, particularly blood clots, infections, and peripheral neuropathy. Kidney function should be assessed before and during treatment, and doses may need adjustment. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is highly teratogenic and must not be used during pregnancy. Women of childbearing potential must use two reliable forms of contraception and undergo regular pregnancy testing. Men must use condoms during and for at least 4 weeks after stopping treatment. If you are planning to become pregnant, discuss with your doctor well in advance to plan a safe approach.
🏥 Post-Surgery Considerations
This medicine can increase the risk of bleeding and blood clots after surgery. Inform your surgeon that you are taking this medicine. Your doctor may recommend stopping the medicine temporarily before surgery and may prescribe blood thinners to prevent clots. Follow your doctor's instructions carefully.
🦷 Dental Procedures
This medicine can increase the risk of bleeding and infection after dental procedures. Inform your dentist that you are taking this medicine. Your dentist may recommend antibiotics or other precautions. Do not undergo dental procedures without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause fatigue, dizziness, and peripheral neuropathy, which may affect your ability to exercise safely. Avoid high-impact activities that could increase the risk of bleeding or injury. Consult your doctor before starting any new exercise program. If you experience numbness, tingling, or weakness in your limbs, stop exercising and inform your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause fatigue, dizziness, and difficulty concentrating, which may affect your ability to drive or operate machinery. Avoid driving until you know how this medicine affects you. You may need to take time off work for treatment and monitoring. Talk to your employer about flexible work arrangements if needed. Avoid close contact with sick colleagues, and practice good hand hygiene.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor may decide to stop treatment if you experience severe side effects, if your disease progresses, or if you complete the planned course. If you need to stop for any reason, your doctor will provide guidance on monitoring and follow-up.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of second primary cancers, including leukemia and lymphoma. It can also cause persistent peripheral neuropathy, which may not improve after stopping the medicine. Regular monitoring of blood counts, liver and kidney function, and thyroid function is necessary. Some patients may develop blood clots or infections that require ongoing management. The benefits of continued treatment should be weighed against these risks by your healthcare team.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A potential treatment option for eligible patients with multiple myeloma.
Evidence: Well-establishedAnother class of medicines used to treat multiple myeloma.
Evidence: Well-establishedIncludes blood transfusions, growth factors, and pain management to improve quality of life.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided while taking this medicine because of the increased risk of infection. Inactivated vaccines are generally safe, but their effectiveness may be reduced due to the immunomodulatory effects of this medicine. Consult your doctor before receiving any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature between 20°C and 25°C.
❌ DON'T
Do not refrigerate or freeze.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not share this medicine with others.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a letter from your doctor explaining your medical condition and the need for this medicine. Keep the medicine in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about how to adjust the dosing schedule. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The time to see an effect varies by condition. In myelodysplastic syndromes, improvement in blood counts may be seen within 4 to 8 weeks. In multiple myeloma, it may take several weeks to months to see a response.
A: Yes, this medicine can be taken with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose and less than 12 hours have passed, take it as soon as you remember. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is an immunomodulatory agent, not a traditional chemotherapy drug. It works by modifying the immune system and targeting cancer cells in a different way.
A: No, this medicine can cause severe birth defects. Women of childbearing potential must use two reliable forms of contraception and undergo regular pregnancy testing.
🤔 Common Patient Concerns
🔄 Substitutes for lenated 10mg capsule
View AllAlternative brands with exact same active ingredient:
-
lenangio 10 capsuleDr Reddy's Laboratories Ltd ₹1,044.00 63.7% CHEAPER
-
lenmid 10 capsuleCipla Ltd ₹1,098.47 61.8% CHEAPER
-
laviat 10mg capsuleZydus Cadila ₹1,220.12 57.6% CHEAPER
-
ledomed 10mg capsuleMedicamen Biotech Ltd ₹1,260.00 56.2% CHEAPER
-
lenava 10 capsuleGLS Pharma Ltd. ₹1,360.31 52.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Lenalidomide is a traditional chemotherapy that causes severe hair loss.
Fact: This medicine is an immunomodulatory agent, not a classic chemotherapy. Hair loss is not a common side effect. - Myth: You can stop taking lenalidomide once you feel better.
Fact: This medicine must be taken exactly as prescribed. Stopping early can lead to disease relapse. - Myth: Lenalidomide is safe during pregnancy.
Fact: This medicine is highly teratogenic and can cause severe birth defects. It is absolutely contraindicated in pregnancy.
🔄 Alternative Options
Generic Alternatives
- Lenalidomide
Brand Alternatives
- Lenangio 10 Capsule
- Revlimid
- Lenalid