Enteromycetin Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Unusual tiredness, weakness, or pale skin
- Easy bruising or bleeding
- Sore throat, fever, or other signs of infection
- Severe abdominal pain or persistent vomiting
- Blood in stool or vomit
- Swelling of face, lips, or throat, or difficulty breathing
- Vision changes such as blurred vision or loss of vision
- Numbness, tingling, or burning in hands or feet
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is larmycetin 125mg/5ml suspension used for?
This medicine is an oral antibiotic suspension containing chloramphenicol, used to treat serious bacterial infections like typhoid fever and meningitis when other antibiotics are not suitable. It works by stopping bacteria from making proteins. It can cause serious blood disorders, so it must be used under strict medical supervision with regular blood tests.
- Generic Name: Chloramphenicol (125mg/5ml)
- Manufacturer: Lark Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 larmycetin 125mg/5ml suspension के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरैम्फेनिकॉल नामक एंटीबायोटिक का मौखिक सस्पेंशन है, जिसका उपयोग गंभीर बैक्टीरियल संक्रमणों जैसे टाइफाइड बुखार, मेनिनजाइटिस और कुछ अन्य संक्रमणों के इलाज के लिए किया जाता है। यह दवा बैक्टीरिया के प्रोटीन बनाने की प्रक्रिया को रोककर उन्हें मारती है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए क्योंकि इससे रक्त विकार जैसे गंभीर दुष्प्रभाव हो सकते हैं। इसका उपयोग सामान्य संक्रमणों के लिए नहीं किया जाता।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, दस्त, पेट दर्द और स्वाद में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में अस्थि मज्जा का दमन, एप्लास्टिक एनीमिया, गंभीर एलर्जी प्रतिक्रियाएं, तंत्रिका क्षति और दृष्टि संबंधी समस्याएं शामिल हैं। यदि आपको असामान्य थकान, पीलापन, आसान चोट लगना, गले में खराश या बुखार महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर के पर्चे पर ही लें। इसे कभी भी बिना डॉक्टर की सलाह के न लें। इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों और दवाओं के बारे में बताएं। इलाज के दौरान नियमित रूप से रक्त परीक्षण करवाना आवश्यक है। शराब का सेवन न करें। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से मिलें। दवा को बच्चों की पहुंच से दूर रखें।
💊 larmycetin 125mg/5ml suspension Uses & Benefits
[{"condition":"Typhoid fever","description":"Used to treat typhoid fever caused by Salmonella typhi when other antibiotics are not suitable or effective.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Used in certain cases of bacterial meningitis, often in combination with other antibiotics, when the bacteria are susceptible.","evidence":"Well-established"},{"condition":"Serious respiratory tract infections","description":"May be used for severe respiratory infections caused by susceptible bacteria when safer options are not available.","evidence":"Limited"},{"condition":"Bacteremia","description":"Used for bloodstream infections caused by susceptible organisms in specific clinical situations.","evidence":"Limited"},{"condition":"Rickettsial infections","description":"Effective against certain rickettsial infections such as Rocky Mountain spotted fever, though other antibiotics are often preferred.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Anthrax","description":"May be used as an alternative treatment for anthrax in certain situations, but this is not a primary approved use.","evidence":"Limited"},{"condition":"Plague","description":"Sometimes used as an alternative for treating plague, but other antibiotics are generally preferred.","evidence":"Limited"}]
Primary treatment for: Typhoid fever
Also treats: Bacterial meningitis, Rickettsial infections, Serious respiratory tract infections, Bacteremia
📋 Drug Information
| Generic Name(s) | Chloramphenicol (125mg/5ml) |
| Brand Name | larmycetin 125mg/5ml suspension |
| Manufacturer | Lark Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OTOLOGICALS |
| Action Class | Chloramphenicol |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not freeze. Keep out of reach of children. |
| Shelf Life | Typically 24 months from the date of manufacture, but check the expiry date on the packaging. Do not use after the expiry date. |
| WHO Guideline | Chloramphenicol is included in the WHO Model List of Essential Medicines for the treatment of certain serious bacterial infections, including meningitis and typhoid fever, when other options are not available or not effective. However, it is not a first-line agent for most infections due to safety concerns. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) recommends chloramphenicol as an alternative treatment for typhoid fever in specific situations, but it is not a first-line agent due to the availability of safer antibiotics. It may be used for other serious infections based on susceptibility testing and clinical judgment. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to the 50S subunit of the bacterial ribosome, which is the cell structure responsible for making proteins. By binding to this subunit, it blocks the action of an enzyme called peptidyl transferase, which is needed to form peptide bonds between amino acids. This prevents the bacteria from building essential proteins, leading to stopped growth and eventually death of the bacteria. Because it targets a structure found only in bacteria, it does not affect human cells in the same way, but it can still cause side effects in humans, especially in the bone marrow.
Mechanism Steps
💡 How to Take larmycetin 125mg/5ml suspension
Strength: Oral suspension: 125 mg of chloramphenicol per 5 ml.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the type and severity of infection, the patient's age, weight, kidney and liver function, and other factors. For adults, a typical dose might be 50 to 100 mg per kilogram of body weight per day, divided into four doses given every 6 hours. However, this is only a general guideline. The exact dose and duration must be determined by your doctor. Do not self-medicate. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally avoided in newborns and premature infants due to the risk of gray baby syndrome. In older children, the dose is individualized by a pediatrician based on weight and clinical condition. Never give this medicine to a child without a doctor's prescription. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially bone marrow suppression. Dose adjustment may be necessary based on kidney and liver function. Close monitoring is recommended. Consult a doctor for individualized dosing. |
| Renal Impairment | Dose adjustment may be needed in patients with severe kidney impairment. Since the medicine is partly excreted unchanged by the kidneys, accumulation can occur. Monitor kidney function and adjust dose as advised by a doctor. |
| Hepatic Impairment | Dose reduction may be necessary in patients with liver disease because the medicine is metabolized in the liver. Close monitoring of liver function and blood counts is recommended. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose is not fixed and depends on the indication, patient's weight, and clinical response. It should not exceed the dose prescribed by your doctor. In general, doses above 100 mg/kg/day are not recommended due to increased risk of bone marrow suppression. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of larmycetin 125mg/5ml suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Phenytoin | Major | |
| Rifampicin | Major | |
| Paracetamol | Moderate | |
| Oral hypoglycemics | Moderate | |
| Cyclosporine | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Chemotherapy agents | Major | |
| Alcohol | Moderate |
🚨 Major Interactions
- Warfarin
- Phenytoin
- Rifampicin
- Other bone marrow suppressants (e.g., chemotherapy agents)
⚡ Moderate Interactions
- Paracetamol (acetaminophen)
- Oral hypoglycemics (e.g., tolbutamide)
- Cyclosporine
🍷 Alcohol Interaction
Avoid drinking alcohol while taking this medicine. Alcohol can increase the risk of liver problems and may worsen stomach side effects. It can also increase the risk of bone marrow suppression.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to chloramphenicol or any component of the formulation","History of bone marrow suppression or blood dyscrasias","Use in treating trivial or minor infections where safer antibiotics are available","Use as a prophylactic antibiotic","Use in newborns and premature infants due to risk of gray baby syndrome","Concurrent use with other drugs that cause bone marrow suppression, unless absolutely necessary"]
⚠️ Warnings & Precautions
["This medicine can cause serious and potentially fatal blood disorders, including aplastic anemia and bone marrow suppression. Use only when clearly needed and under close medical supervision.","Blood tests to monitor blood cell counts are essential before, during, and after treatment.","Do not use this medicine for minor infections or without a prescription.","Avoid alcohol while taking this medicine.","Inform your doctor if you have liver or kidney disease, as dose adjustments may be needed.","This medicine may interact with many other drugs. Always inform your doctor about all medicines you are taking.","Use with caution in elderly patients, who may be more susceptible to side effects.","Do not stop taking this medicine without consulting your doctor, even if you feel better.","Keep this medicine out of reach of children.","Dispose of unused medicine properly and do not share with others."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. Because of the potential for serious side effects in the infant, it is generally not recommended during breastfeeding. If it must be used, the infant should be monitored for signs of bone marrow suppression, and alternative feeding methods may be considered. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe bone marrow suppression, nausea, vomiting, and in newborns, gray baby syndrome. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include blood transfusions, administration of activated charcoal if taken recently, and close monitoring of blood counts. There is no specific antidote. Hemodialysis or peritoneal dialysis may be considered in severe cases but is not very effective at removing the drug.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
This medicine must only be taken exactly as prescribed by a qualified doctor. Do not use it for minor infections or without a prescription. Before starting this medicine, tell your doctor about all your medical conditions, especially any blood disorders, liver or kidney problems, or allergies. Inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, as this medicine can interact with many other medications. While taking this medicine, your doctor may order regular blood tests to check your blood cell counts. Avoid alcohol while taking this medicine. If you experience any unusual symptoms such as fever, sore throat, easy bruising, or bleeding, seek medical attention immediately. Do not stop taking this medicine without consulting your doctor, even if you feel better, to prevent the infection from returning. Keep this medicine out of reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, especially bone marrow suppression. Close monitoring of blood counts and liver and kidney function is recommended. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. It may harm the fetus. Use effective contraception while taking this medicine and for a period after stopping. Consult your doctor for personalized advice.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery and can increase the risk of bleeding or other complications. Your doctor may advise you to stop the medicine before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may increase the risk of bleeding and interact with other medications. Your dentist may recommend postponing non-urgent procedures until you have completed treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may feel tired or weak. Avoid strenuous exercise until you feel better. Light activity like walking may be fine if you feel up to it. If you experience dizziness, confusion, or vision changes, do not exercise and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause side effects like nausea, headache, or fatigue, which can affect your ability to work or drive. If you experience confusion, dizziness, or vision changes, avoid driving or operating heavy machinery. Most people can continue their normal activities as tolerated, but take it easy until you know how the medicine affects you.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to the infection returning and may increase the risk of antibiotic resistance. Your doctor will tell you when to stop based on your clinical response and test results. If you experience serious side effects, contact your doctor immediately; they may advise you to stop.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of serious blood disorders, including aplastic anemia and bone marrow suppression. It may also cause peripheral neuropathy and optic neuritis. Regular blood tests are essential during prolonged therapy. The medicine should only be used for as long as necessary and under close medical supervision. If you experience any unusual symptoms, report them to your doctor immediately.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Safer antibiotics like azithromycin, ceftriaxone, or cefixime may be used for many infections for which this medicine is considered.
Evidence: Well-establishedRest, hydration, and fever control can help manage symptoms while the infection resolves.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live vaccines. Avoid receiving live vaccines while taking this medicine and for a short period after stopping. Consult your doctor for specific advice regarding vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Shake well before each use
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription and a doctor's note explaining why you need it, especially for international travel. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust your dosing schedule gradually in consultation with your doctor. Do not pack it in checked luggage; keep it in your carry-on bag. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 48 hours after starting this medicine, but it may take several days for the full effect. It is important to complete the full course as prescribed.
A: Yes, you can take this medicine with or without food. If it upsets your stomach, taking it with a small amount of food or milk may help.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine may harm the fetus and is generally not recommended during pregnancy unless the benefits clearly outweigh the risks. Consult your doctor immediately if you are pregnant or planning to become pregnant.
A: No, you must complete the full course prescribed by your doctor, even if you feel better, to ensure the infection is fully cleared and to prevent resistance.
🤔 Common Patient Concerns
🔄 Substitutes for larmycetin 125mg/5ml suspension
View AllAlternative brands with exact same active ingredient:
-
fencol 125mg/5ml suspensionInd Swift Laboratories Ltd ₹16.41 77% CHEAPER
-
chloraxin 125mg/5ml suspensionCipla Ltd ₹18.75 73.7% CHEAPER
-
phenicol 125mg/5ml suspensionTorque Pharmaceuticals Pvt Ltd ₹19.75 72.3% CHEAPER
-
wocol 125mg/5ml suspensionWockhardt Ltd ₹26.83 62.4% CHEAPER
-
chemocetin 125mg suspensionChemo Biological ₹28.00 60.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a safe antibiotic for common infections.
Fact: This medicine is reserved for serious infections because it can cause severe blood disorders. It is not a first-choice antibiotic for common infections. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course prescribed by your doctor to prevent the infection from returning and to reduce the risk of resistance. - Myth: This medicine is safe for newborns.
Fact: This medicine is not safe for newborns due to the risk of gray baby syndrome, a potentially fatal condition.
🔄 Alternative Options
Generic Alternatives
- Chloramphenicol oral suspension 125 mg/5 ml (various manufacturers)
Brand Alternatives
- Enteromycetin suspension