lamolet 100mg tablet - Lamotrigine (100mg) medicine

Lamotrigine 100 mg Tablet DT: Complete Medicine Guide

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🏭 Zeelab Pharmacy Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Skin rash with blisters, peeling, or sores in the mouth
  • Yellowing of skin or eyes, dark urine, or severe abdominal pain
  • Unusual bleeding or bruising
  • Persistent sore throat with fever
  • Severe headache with neck stiffness and sensitivity to light
  • Suicidal thoughts or behaviour
  • Seizures that worsen or change in pattern

If experiencing severe symptoms, call emergency services immediately.

What is lamolet 100mg tablet used for?

This medicine is an antiepileptic drug used to treat epilepsy and bipolar disorder. It works by stabilising electrical activity in the brain. It must be started at a low dose and increased slowly to reduce the risk of serious skin rash.

  • Generic Name: Lamotrigine (100mg)
  • Manufacturer: Zeelab Pharmacy Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lamolet 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लैमोट्रिजिन 100 मिलीग्राम की गोली है जिसका उपयोग मिर्गी (एपिलेप्सी) और बाइपोलर डिसऑर्डर के इलाज में किया जाता है। यह दौरे (सीज़र) की आवृत्ति को कम करने में मदद करती है और मूड को स्थिर रखने में सहायक होती है। यह दवा दिमाग में इलेक्ट्रिकल गतिविधि को संतुलित करके काम करती है। इसे डॉक्टर की सलाह के अनुसार धीरे-धीरे बढ़ाया जाता है ताकि त्वचा पर गंभीर दाने पड़ने का खतरा कम हो। इस दवा को अचानक बंद नहीं करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, नींद आना, जी मिचलाना, दस्त और त्वचा पर दाने शामिल हैं। कभी-कभी गंभीर त्वचा प्रतिक्रियाएँ जैसे स्टीवंस-जॉनसन सिंड्रोम हो सकती हैं, इसलिए किसी भी दाने को तुरंत डॉक्टर को बताएं। अन्य गंभीर दुष्प्रभावों में रक्त विकार, यकृत की समस्या और आत्मघाती विचार शामिल हो सकते हैं।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। गर्भवती होने या स्तनपान कराने पर डॉक्टर से सलाह लें। इस दवा को अचानक बंद न करें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन न चलाएं। नियमित रूप से डॉक्टर से मिलें और जांच कराएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 lamolet 100mg tablet Uses & Benefits

[{"condition":"Epilepsy (partial-onset seizures)","description":"Used as add-on therapy or monotherapy to reduce the frequency of partial seizures in adults and children.","evidence":"Well-established"},{"condition":"Epilepsy (generalised seizures)","description":"Effective in reducing generalised tonic-clonic seizures and seizures associated with Lennox-Gastaut syndrome.","evidence":"Well-established"},{"condition":"Bipolar disorder (maintenance)","description":"Helps delay the time to mood episodes, particularly depressive episodes, in adults with bipolar I disorder.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes prescribed off-label for chronic neuropathic pain, though evidence is limited.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Occasionally used off-label to prevent migraines, but not first-line.","evidence":"Limited"}]

Primary treatment for: Epilepsy

Also treats: Bipolar disorder

📋 Drug Information

Generic Name(s)Lamotrigine (100mg)
Brand Namelamolet 100mg tablet
ManufacturerZeelab Pharmacy Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSodium channel modulators (AED)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Start this medicine at a low dose and increase gradually as prescribed to minimise the risk of serious skin rash.
2
Instruct patients to report any rash, fever, or mouth sores immediately, as these may be signs of a serious reaction.
3
Monitor for mood changes and suicidal thoughts, especially in patients with bipolar disorder.
4
Adjust the dose when used with valproate or enzyme-inducing antiepileptic drugs.
5
Advise patients not to stop the medicine abruptly to avoid withdrawal seizures.
6
Regularly assess liver and kidney function in patients with impairment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Seizures
This medicine is commonly prescribed for epilepsy.
Likely Use
✅
Mood swings
This medicine is used for bipolar disorder.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Food does not significantly affect the extent of absorption.
DistributionThis medicine distributes widely into body tissues. It crosses the blood-brain barrier and is also distributed into breast milk.
Protein BindingApproximately 55% bound to plasma proteins.
MetabolismThis medicine is primarily metabolised in the liver, mainly by glucuronic acid conjugation via UDP-glucuronosyltransferases. The main metabolite is an inactive glucuronide conjugate.
Half-LifeThe elimination half-life is approximately 25 to 33 hours in healthy adults. It is prolonged in patients with liver impairment and shortened when used with enzyme-inducing drugs.
ExcretionThis medicine and its metabolites are primarily excreted in the urine, with about 94% of a dose recovered in urine and 2% in faeces.
BioavailabilityThe oral bioavailability is approximately 98%.
Onset of ActionThe onset of therapeutic effect for seizure control may take several weeks, as the dose is gradually increased. For mood stabilisation, it may take 4 to 6 weeks.
Peak Plasma TimePeak plasma concentrations are reached approximately 1.5 to 4.8 hours after oral administration.
Duration of ActionThe duration of action is not precisely defined, but the half-life supports once or twice daily dosing. Steady-state levels are achieved after about 5 days of consistent dosing.

How It Works

This medicine works by inhibiting voltage-sensitive sodium channels in the brain, which stabilises neuronal membranes and reduces the release of excitatory neurotransmitters, particularly glutamate. This action helps to prevent the excessive electrical activity that leads to seizures and mood instability.

Mechanism Steps

1
Sodium channel blockade: This medicine binds to voltage-gated sodium channels in their inactive state, prolonging the inactivation phase and reducing neuronal excitability.
2
Reduced glutamate release: By stabilising sodium channels, this medicine decreases the release of glutamate, an excitatory neurotransmitter that contributes to seizure activity.
3
Mood stabilisation: The exact mechanism for mood stabilisation is not fully understood, but it likely involves modulation of glutamate and other neurotransmitter systems in the brain.

💡 How to Take lamolet 100mg tablet

Strength: This medicine is available as a 100 mg immediate-release tablet for oral use.

1Disperse the tablet in a small amount of water (at least 5 mL) and swirl to dissolve.
2Drink the entire mixture immediately.
3Rinse the glass with a little more water and drink to ensure full dose.
4Take with or without food, but be consistent.
5Follow your doctor's titration schedule exactly.

Dosage Information

Adult DosageThe dose of this medicine must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. For epilepsy, the usual starting dose is 25 mg once daily for 2 weeks, then increased gradually. The maintenance dose typically ranges from 100 mg to 200 mg daily, divided into one or two doses. For bipolar disorder, the starting dose is 25 mg once daily for 2 weeks, then gradually increased to a target dose of 100 mg to 200 mg daily. When used with valproate, the dose should be halved. When used with enzyme-inducing drugs, the dose may need to be doubled. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Dose selection should be cautious, and renal function should be considered. Follow your doctor's instructions.
Renal ImpairmentDose adjustment may be necessary in patients with severe renal impairment. Consult your doctor for individualized dosing.
Hepatic ImpairmentDose reduction is recommended in patients with moderate to severe hepatic impairment. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose is not established from the available information. It varies by indication and patient factors. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.
📌 Missed multiple doses
→ Contact your doctor before restarting.
💡 Dose may need to be re-titrated to avoid rash.

⚠️ Side Effects of lamolet 100mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. Consult doctor if it persists.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness. Consult doctor if it interferes with daily life.
Nausea (Common (5-10%))
Take with food to reduce stomach upset. Consult doctor if it continues.
Skin rash (Common (5-10%))
Report any rash to your doctor immediately, as it can be a sign of a serious reaction.

🚨 Serious Side Effects

Stevens-Johnson syndrome (Rare (<0.1%))
Seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in the mouth.
Blood dyscrasias (Rare (<0.1%))
Report unusual bleeding, bruising, or persistent sore throat to your doctor promptly.
Liver failure (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Aseptic meningitis (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, fever, neck stiffness, or sensitivity to light.

⚠️ Rare Side Effects

Agranulocytosis
Seek immediate medical attention if you develop fever, chills, or sore throat.
Pancreatitis
Seek immediate medical attention if you experience severe abdominal pain radiating to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Valproate Major
Carbamazepine Major
Phenytoin Moderate
Rifampicin Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Valproate
  • Carbamazepine

⚡ Moderate Interactions

  • Phenytoin
  • Rifampicin

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to lamotrigine or any component of the formulation","History of serious skin rash (e.g., Stevens-Johnson syndrome) with lamotrigine"]

⚠️ Warnings & Precautions

["Serious skin rashes, including Stevens-Johnson syndrome, can occur, especially in the first 8 weeks of treatment. Report any rash immediately.","Do not stop this medicine abruptly, as it can cause seizures to worsen.","May cause dizziness or drowsiness. Avoid driving or operating machinery until you know how it affects you.","May increase the risk of suicidal thoughts or behaviour. Monitor for mood changes.","Use with caution in patients with liver or kidney impairment.","May interact with other antiepileptic drugs; dose adjustments may be necessary."]

🤱 Lactation Safety

This medicine passes into breast milk. Breastfeeding is not recommended while taking this medicine unless the benefits outweigh the risks. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose of this medicine can cause symptoms such as dizziness, headache, drowsiness, and nausea. In severe cases, it can lead to seizures, coma, or death. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. If you miss several doses, consult your doctor before restarting, as the dose may need to be re-titrated.

Additional Safety Advice

General Safety

Before starting this medicine, tell your doctor if you have kidney or liver problems, as the dose may need adjustment. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not stop taking this medicine suddenly, as this can cause seizures to return or worsen. Always follow the gradual dose increase schedule prescribed by your doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause dizziness or drowsiness. Alcohol may increase drowsiness and should be avoided. Keep all appointments for blood tests and monitoring. Store this medicine at room temperature, away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Never double the dose to make up for a missed one.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Dose selection should be cautious, and kidney function should be considered. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before conception. This medicine may be used during pregnancy if the benefits outweigh the risks. Your doctor may adjust the dose and monitor levels closely. Folic acid supplementation is recommended.

🏥 Post-Surgery Considerations

Inform your surgeon and anaesthesiologist that you are taking this medicine. It may interact with anaesthetic agents. Your doctor may advise you to continue or temporarily adjust the dose around the time of surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or increase the risk of bleeding. Your dentist may take precautions accordingly.

💚 Lifestyle Tips for Better Results

🏃
Maintain a regular sleep schedule to help reduce seizure triggers.
🥗
Avoid known seizure triggers such as flashing lights or sleep deprivation.
😴
Practice stress management techniques like yoga or meditation.
💧
Keep a diary of seizures or mood changes to share with your doctor.
🧘
Take the medicine at the same time each day to maintain consistent levels.

🏋️ Exercise Considerations

Exercise is generally safe while taking this medicine. However, if you experience dizziness or drowsiness, avoid activities that require balance or coordination, such as cycling or swimming, until you know how the medicine affects you.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Stay well hydrated.
Limit alcohol intake as it can increase drowsiness.
Avoid skipping meals to maintain stable blood sugar levels.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is important to take the medicine regularly and attend follow-up appointments, which may require time off work.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation can cause seizures to return or worsen. Your doctor will gradually reduce the dose if it is appropriate to stop.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored appropriately. Regular follow-up is needed to assess seizure control, mood stability, and any emerging side effects. Blood tests may be done periodically to check liver and kidney function. Some patients may experience tolerance or changes in efficacy over time. Do not stop the medicine without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ketogenic diet

A high-fat, low-carbohydrate diet that can help reduce seizures in some patients with epilepsy, especially children.

Evidence: Well-established for certain types of epilepsy
Vagus nerve stimulation

A device implanted under the skin that sends electrical impulses to the vagus nerve to reduce seizures.

Evidence: Well-established for refractory epilepsy

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of doses. Carry enough supply for the entire trip and a little extra in case of delays. Check customs regulations for controlled substances before travelling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with epilepsy
She was started on this medicine as add-on therapy. Her dose was increased slowly over several weeks. She experienced mild dizziness initially, which resolved. Her seizure frequency reduced significantly, and she was able to resume driving after being seizure-free for a year.
💡 Lesson: Gradual dose titration and patience are key to tolerating this medicine and achieving seizure control.
👤 A 45-year-old man with bipolar disorder
He had frequent depressive episodes. This medicine was added to his treatment. After a few weeks, his mood stabilised, and he had fewer depressive episodes. He reported mild nausea, which was managed by taking the medicine with food.
💡 Lesson: This medicine can be effective for preventing mood episodes in bipolar disorder, but it takes time to work and side effects can be managed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It may take several weeks to reach the full therapeutic effect. The dose is increased gradually to reduce the risk of side effects.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop suddenly. Stopping can cause seizures to return or worsen. Always consult your doctor before stopping.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for lamolet 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a cure for epilepsy.
    Fact: This medicine helps control seizures but does not cure epilepsy. Treatment is usually long-term.
  • Myth: You can stop this medicine once you feel better.
    Fact: Stopping suddenly can cause seizures to return or worsen. Always consult your doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Lamotrigine 100 mg dispersible tablet

Brand Alternatives

  • Lamitor DT 100 mg
  • Lametec 100 mg
  • Lamez 100 mg

📊 Comparison with Similar Medicines

[{"medicine":"Lamotrigine","class":"Phenyltriazine","primary_use":"Epilepsy, bipolar disorder","key_side_effect":"Skin rash"},{"medicine":"Levetiracetam","class":"Pyrrolidine","primary_use":"Epilepsy","key_side_effect":"Behavioural changes"},{"medicine":"Valproate","class":"Fatty acid derivative","primary_use":"Epilepsy, bipolar disorder","key_side_effect":"Weight gain, liver toxicity"}]

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