Edeflow 100 Tablet (Spironolactone 100 mg): Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Muscle weakness or irregular heartbeat (signs of high potassium)
- Severe dizziness or fainting
- Decreased urine output
- Swelling of face, lips, or throat, or difficulty breathing
- Severe abdominal pain or vomiting blood
- Yellowing of skin or eyes (jaundice)
- Unusual bleeding or bruising
- Severe rash with blisters or peeling skin
If experiencing severe symptoms, call emergency services immediately.
What is lactone 100mg tablet used for?
This medicine contains spironolactone 100 mg, a potassium-sparing diuretic used to treat fluid retention, high blood pressure, and heart failure. It works by blocking aldosterone, helping the kidneys remove excess fluid while retaining potassium. It is a prescription medicine and requires regular monitoring of potassium and kidney function.
- Generic Name: Spironolactone (100mg)
- Manufacturer: Aimil Pharmaceuticals India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lactone 100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा स्पिरोनोलैक्टोन 100 मिलीग्राम युक्त एक टैबलेट है। यह मूत्रवर्धक (डाययूरेटिक) दवाओं के वर्ग में आती है और एल्डोस्टेरोन रिसेप्टर को ब्लॉक करके काम करती है। इसका उपयोग हृदय विफलता, उच्च रक्तचाप, यकृत सिरोसिस और नेफ्रोटिक सिंड्रोम में होने वाले शरीर में पानी के जमाव (एडिमा) के इलाज के लिए किया जाता है। यह प्राइमरी हाइपरएल्डोस्टेरोनिज्म (कॉन्स सिंड्रोम) और पोटेशियम की कमी के इलाज में भी प्रयोग की जाती है। यह दवा पोटेशियम को बनाए रखती है और सोडियम तथा पानी को बाहर निकालती है। यह केवल डॉक्टर के पर्चे पर ही मिलती है और इसका सेवन डॉक्टर की सलाह के अनुसार ही करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, नींद आना, थकान, जी मिचलाना, उल्टी, दस्त, पेट में ऐंठन और पुरुषों में स्तनों में कोमलता या वृद्धि (गाइनेकोमास्टिया) शामिल हैं। गंभीर दुष्प्रभावों में उच्च पोटेशियम स्तर (हाइपरकेलेमिया) के लक्षण जैसे मांसपेशियों में कमजोरी, अनियमित दिल की धड़कन, और सुन्नपन; गंभीर एलर्जी प्रतिक्रियाएं जैसे दाने, खुजली, चेहरे, होंठ या गले में सूजन, और सांस लेने में कठिनाई; और गुर्दे की समस्याओं के संकेत जैसे पेशाब की मात्रा में कमी शामिल हैं। यदि आपको कोई भी दुष्प्रभाव लगातार या परेशान करने वाला लगे तो अपने डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको गुर्दे की बीमारी, यकृत की बीमारी, हृदय रोग, मधुमेह है, या आप कोई अन्य दवा ले रहे हैं, विशेष रूप से पोटेशियम सप्लीमेंट, एसीई इनहिबिटर, एआरबी, एनएसएआईडी, या अन्य मूत्रवर्धक। पोटेशियम सप्लीमेंट या पोटेशियम युक्त नमक के विकल्प डॉक्टर की सलाह के बिना न लें, क्योंकि इससे खतरनाक रूप से उच्च पोटेशियम स्तर हो सकता है। इस दवा को लेते समय शराब से बचें, क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। यह दवा चक्कर का कारण बन सकती है; जब तक आपको पता न चले कि यह आपको कैसे प्रभावित करती है, वाहन चलाने या भारी मशीनरी चलाने से बचें। पर्याप्त तरल पदार्थ पिएं जब तक कि आपके डॉक्टर अन्यथा सलाह न दें। इस दवा को लेते समय नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट स्तर (विशेष रूप से पोटेशियम) की निगरानी आवश्यक है। डॉक्टर से परामर्श किए बिना इस दवा को अचानक बंद न करें।
💊 lactone 100mg tablet Uses & Benefits
- [{"condition":"Heart failure with reduced ejection fraction","description":"This medicine is used to reduce fluid retention, improve symptoms, and decrease hospitalizations in patients with heart failure.
- It is often part of standard heart failure therapy.","evidence":"Well-established"},{"condition":"Hypertension (high blood pressure)","description":"This medicine helps lower blood pressure by removing excess fluid and blocking aldosterone effects.
- It is often used as an add-on therapy when other blood pressure medicines are not enough.","evidence":"Well-established"},{"condition":"Edema (fluid retention) due to liver cirrhosis","description":"This medicine is used to treat ascites and edema in patients with liver cirrhosis.
- It helps remove excess fluid from the abdomen and legs.","evidence":"Well-established"},{"condition":"Edema due to nephrotic syndrome","description":"This medicine can help reduce fluid retention in patients with kidney disease, particularly nephrotic syndrome.","evidence":"Established"},{"condition":"Primary hyperaldosteronism (Conn's syndrome)","description":"This medicine is used to treat high aldosterone levels, which can cause high blood pressure and low potassium.
- It blocks the effects of aldosterone.","evidence":"Well-established"},{"condition":"Hypokalemia (low potassium levels)","description":"This medicine helps raise potassium levels by reducing potassium loss through urine.
- It is used when low potassium is due to other diuretics.","evidence":"Established"}]
Off-label uses: [{"condition":"Acne and hirsutism in women with polycystic ovary syndrome (PCOS)","description":"This medicine has anti-androgen effects and is sometimes prescribed off-label to treat acne and excessive hair growth in women with PCOS.","evidence":"Limited"},{"condition":"Male pattern hair loss (androgenetic alopecia)","description":"This medicine is occasionally used off-label to treat hair loss in men due to its anti-androgen properties, but evidence is limited.","evidence":"Limited"},{"condition":"Premenstrual syndrome (PMS)","description":"This medicine may be used off-label to reduce premenstrual fluid retention and symptoms, but evidence is not strong.","evidence":"Limited"}]
Primary treatment for: Heart failure
Also treats: Hypertension, Liver cirrhosis with ascites, Nephrotic syndrome, Primary hyperaldosteronism, Hypokalemia
📋 Drug Information
| Generic Name(s) | Spironolactone (100mg) |
| Brand Name | lactone 100mg tablet |
| Manufacturer | Aimil Pharmaceuticals India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Potassium- sparing Diuretics |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by competitively binding to the mineralocorticoid receptor (aldosterone receptor) in the distal tubules of the kidneys. Aldosterone normally promotes sodium reabsorption and potassium excretion. By blocking aldosterone, this medicine increases the excretion of sodium and water while retaining potassium. This leads to diuresis (increased urine production) and a reduction in fluid retention. Additionally, this medicine has anti-androgenic effects by blocking androgen receptors, which can lead to gynecomastia and is used off-label for conditions like acne and hirsutism.
Mechanism Steps
💡 How to Take lactone 100mg tablet
Strength: Tablet, 100 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for edema is 25-200 mg per day, taken as a single dose or in divided doses. For hypertension, the usual dose is 25-100 mg per day. For heart failure, the usual dose is 12.5-25 mg per day, which may be increased to 50 mg per day if needed. For primary hyperaldosteronism, the dose is 100-400 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and electrolyte imbalances. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose reduction may be necessary. Monitor kidney function and potassium levels closely. Contraindicated in severe kidney disease. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction may be necessary. Monitor liver function and electrolytes. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg, but doses above 100 mg are rarely used. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lactone 100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Potassium supplements | Major | |
| ACE inhibitors | Major | |
| ARBs | Major | |
| Potassium-sparing diuretics | Major | |
| NSAIDs | Major | |
| Lithium | Major | |
| Digoxin | Major | |
| Corticosteroids | Moderate | |
| Other diuretics | Moderate | |
| Cholestyramine | Moderate |
🚨 Major Interactions
- Potassium supplements
- ACE inhibitors (e.g., lisinopril, enalapril)
- Angiotensin II receptor blockers (ARBs) (e.g., losartan, valsartan)
- Potassium-sparing diuretics (e.g., amiloride, triamterene)
- NSAIDs (e.g., ibuprofen, naproxen)
- Lithium
- Digoxin
⚡ Moderate Interactions
- Corticosteroids (e.g., prednisone)
- Other diuretics (e.g., furosemide, hydrochlorothiazide)
- Carbenoxolone
- Cholestyramine
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and low blood pressure when taken with this medicine. It is advisable to avoid or limit alcohol consumption while on this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hyperkalemia (high potassium levels)","Severe kidney disease (e.g., acute kidney injury, anuria)","Addison's disease","Hypersensitivity to spironolactone or any component of the tablet","Concomitant use with potassium supplements or potassium-sparing diuretics","Pregnancy (unless clearly needed)","Breastfeeding (unless benefits outweigh risks)"]
⚠️ Warnings & Precautions
["This medicine can cause hyperkalemia. Avoid potassium supplements and salt substitutes containing potassium.","Regular monitoring of potassium and kidney function is essential.","This medicine may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","This medicine may cause gynecomastia in men. Consult your doctor if this occurs.","This medicine can cause menstrual irregularities in women.","Use with caution in patients with liver disease.","This medicine may interact with other medications. Inform your doctor about all medicines you are taking.","Do not stop taking this medicine abruptly without consulting your doctor.","This medicine is not recommended during pregnancy unless clearly needed."]
🤱 Lactation Safety
This medicine passes into breast milk. It is not recommended while breastfeeding unless the benefits outweigh the risks. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe dehydration, electrolyte imbalance, and hyperkalemia. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of electrolytes and vital signs. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have kidney disease, liver disease, heart disease, diabetes, or if you are taking any other medications, especially potassium supplements, ACE inhibitors, ARBs, NSAIDs, or other diuretics. Do not take potassium supplements or salt substitutes containing potassium without your doctor's approval, as this can lead to dangerously high potassium levels. Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. Drink adequate fluids unless your doctor advises otherwise. Regular monitoring of blood pressure, kidney function, and electrolyte levels (especially potassium) is essential while on this medicine. Do not stop taking this medicine abruptly without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor before using this medicine. Keep this medicine out of reach of children and store it as directed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine, particularly dizziness, low blood pressure, and electrolyte imbalances. Start with a lower dose and monitor closely. Regular monitoring of kidney function and potassium levels is essential.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy unless clearly needed. If you are planning to become pregnant, consult your doctor to discuss alternative treatments. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may affect fluid and electrolyte balance during surgery. Your doctor may advise temporary discontinuation before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness. No specific precautions are usually needed, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or low blood pressure, especially when standing up quickly. Avoid strenuous exercise initially until you know how the medicine affects you. Stay hydrated during exercise. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause frequent urination, which can disrupt your workday. Plan your doses to minimize inconvenience. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe hyperkalemia, kidney problems, or allergic reactions, seek immediate medical attention. Your doctor may adjust the dose or switch to another medicine if needed.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to electrolyte imbalances, particularly hyperkalemia, and kidney function changes. It can also cause gynecomastia in men and menstrual irregularities in women. Regular monitoring of potassium, kidney function, and blood pressure is essential. Periodic assessment of the benefit versus risk is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing salt intake can help manage fluid retention and blood pressure.
Evidence: Well-establishedAppropriate physical activity can improve heart function and overall health.
Evidence: Well-establishedLoop or thiazide diuretics may be alternatives, but they have different potassium effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor about appropriate vaccinations, especially if you have heart or kidney disease.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from direct sunlight. If crossing time zones, consult your doctor about adjusting the timing of your doses. Check local customs regulations for carrying prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The diuretic effect begins within 1-2 days, but full therapeutic effect may take 2-3 days or longer.
A: Yes, take it with food to increase absorption and reduce stomach upset.
A: Avoid potassium supplements, salt substitutes containing potassium, and alcohol. Limit potassium-rich foods.
A: It is not recommended during pregnancy unless clearly needed. Consult your doctor.
A: No, do not stop without consulting your doctor as it may worsen your condition.
🤔 Common Patient Concerns
🔄 Substitutes for lactone 100mg tablet
View AllAlternative brands with exact same active ingredient:
-
spilactone 100 mg tabletSun Pharmaceutical Industries Ltd ₹49.00 94.4% COSTLIER
-
silectone 100 tabletJohnlee Pharmaceuticals Pvt Ltd ₹74.06 193.9% COSTLIER
-
edeflow 100 tabletLeeford Healthcare Ltd ₹79.69 216.2% COSTLIER
-
cglactone 100mg tabletCmg Biotech Pvt Ltd ₹85.00 237.3% COSTLIER
-
aldactone 100 tabletRPG Life Sciences Ltd ₹289.43 1048.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a water pill that can be used for weight loss.
Fact: This medicine is a diuretic used for specific medical conditions. It is not a weight loss drug and should not be used for that purpose. - Myth: This medicine can be taken without monitoring potassium levels.
Fact: Regular monitoring of potassium levels is essential because this medicine can cause dangerously high potassium levels. - Myth: This medicine is safe to take with potassium supplements.
Fact: Taking potassium supplements with this medicine can lead to hyperkalemia, which can be life-threatening. - Myth: This medicine works immediately.
Fact: The diuretic effect begins within 1-2 days, but full therapeutic effect may take 2-3 days or longer.
🔄 Alternative Options
Generic Alternatives
- Spironolactone 100 mg tablet
Brand Alternatives
- Aldactone 100 mg tablet
- Spiromide 100 mg tablet