l citrid 2.5mg syrup - Levocetirizine (2.5mg/5ml) medicine

Levocetirizine Syrup: Complete Guide to Uses, Dosage, and Safety

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🏭 Unimarck Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and chronic urticaria.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Irregular heartbeat or palpitations
  • Severe drowsiness or confusion
  • Seizures
  • Severe skin rash or blistering
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is l citrid 2.5mg syrup used for?

This medicine is an antihistamine syrup containing levocetirizine, used to treat allergic symptoms like sneezing, runny nose, and itchy eyes. It works by blocking histamine, providing relief for up to 24 hours. The usual adult dose is 5 mg (10 ml) once daily.

  • Generic Name: Levocetirizine (2.5mg/5ml)
  • Manufacturer: Unimarck Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 l citrid 2.5mg syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी के लक्षणों जैसे छींक, नाक बहना, आंखों में खुजली और पानी आना, और त्वचा पर पित्ती का इलाज करने के लिए उपयोग की जाती है। यह एलर्जी राइनाइटिस और पुरानी पित्ती के लिए प्रभावी है। यह हिस्टामिन को ब्लॉक करके काम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, थकान, मुंह सूखना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी प्रतिक्रिया, दिल की धड़कन अनियमित हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों और दवाओं के बारे में बताएं। गाड़ी चलाने या मशीनरी चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आपको कैसे प्रभावित करती है। शराब का सेवन न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 l citrid 2.5mg syrup Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Chronic idiopathic urticaria","description":"Reduces itching and hives in patients with chronic urticaria.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Helps alleviate itching and redness of the eyes due to allergies.","evidence":"Well-established"},{"condition":"Atopic dermatitis","description":"May be used to control itching associated with eczema.","evidence":"Limited"}]

Off-label uses: [{"condition":"Pruritus due to other causes","description":"Sometimes used to relieve itching from conditions like insect bites or drug reactions.","evidence":"Limited"},{"condition":"Anxiety-related insomnia","description":"Due to its sedative properties, it may be used off-label for short-term sleep aid.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Chronic idiopathic urticaria, Allergic conjunctivitis, Atopic dermatitis

📋 Drug Information

Generic Name(s)Levocetirizine (2.5mg/5ml)
Brand Namel citrid 2.5mg syrup
ManufacturerUnimarck Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassH1 Antihistaminics (second Generation)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine in the evening to minimize daytime drowsiness.
2
Use a proper measuring device to ensure accurate dosing.
3
Avoid alcohol and other sedatives while on this medicine.
4
If you have kidney problems, your doctor may adjust the dose.
5
Do not use for more than 7 days without consulting a doctor.
6
Report any unusual symptoms like palpitations or severe drowsiness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing
This medicine is commonly prescribed for this.
Likely Use
Runny nose
This medicine is commonly prescribed for this.
Likely Use
Itchy eyes
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly absorbed after oral administration. The bioavailability is high, and food does not significantly affect the extent of absorption, although it may delay the time to peak concentration.
DistributionLevocetirizine distributes into body tissues, but its distribution is not extensively characterized. It has a low volume of distribution.
Protein BindingApproximately 90% of levocetirizine is bound to plasma proteins.
MetabolismLevocetirizine undergoes minimal metabolism in the liver. It is primarily excreted unchanged in the urine.
Half-LifeThe elimination half-life of levocetirizine is approximately 6 to 8 hours in adults with normal kidney function.
ExcretionLevocetirizine is primarily excreted unchanged in the urine via glomerular filtration and active tubular secretion.
BioavailabilityThe oral bioavailability of levocetirizine is high, approximately 90% or more.
Onset of ActionThe onset of action is typically within 1 hour after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 0.5 to 1 hour after oral administration.
Duration of ActionThe duration of action is approximately 24 hours, allowing for once-daily dosing in adults.

How It Works

Levocetirizine is the active enantiomer of cetirizine and acts as a selective antagonist at the histamine H1 receptor. By binding to these receptors, it prevents histamine from exerting its effects, thereby reducing allergic symptoms such as vasodilation, increased vascular permeability, and sensory nerve stimulation. It has minimal anticholinergic and antiserotonergic effects, making it less sedating than first-generation antihistamines.

Mechanism Steps

1
Binding to H1 receptors: Levocetirizine binds selectively to histamine H1 receptors on effector cells, preventing histamine from binding.
2
Inhibition of allergic response: This binding inhibits the downstream effects of histamine, such as vasodilation, increased vascular permeability, and nerve stimulation, thereby reducing allergy symptoms.
3
Minimal CNS penetration: Levocetirizine has limited ability to cross the blood-brain barrier, resulting in less sedation compared to first-generation antihistamines.

💡 How to Take l citrid 2.5mg syrup

Strength: Each 5 ml of syrup contains 2.5 mg of levocetirizine.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the exact dose.
3Take the medicine orally, with or without food.
4If taking once daily, take it in the evening.
5Follow the dosage instructions provided by your doctor.
6Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 mg (10 ml of this syrup) once daily in the evening. However, the dose may be adjusted based on the condition being treated and the patient's renal function. For allergic rhinitis, the dose may be taken once daily. For chronic urticaria, the same dose is typically used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosageFor children aged 6 to 12 years, the usual dose is 2.5 mg (5 ml) once daily in the evening. For children aged 2 to 6 years, the dose is 1.25 mg (2.5 ml) once daily. For children under 2 years, safety and efficacy have not been established. Pediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose should be adjusted based on renal function. The usual adult dose may be used if renal function is normal. In case of renal impairment, dose reduction is recommended. Consult a doctor for appropriate dosing.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For mild renal impairment (creatinine clearance 50-80 mL/min), the dose may be 2.5 mg once daily. For moderate impairment (30-50 mL/min), 2.5 mg every other day. For severe impairment (10-30 mL/min), 2.5 mg twice weekly. For end-stage renal disease (creatinine clearance <10 mL/min), contraindicated. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo dose adjustment is required for patients with hepatic impairment alone. However, if hepatic impairment is accompanied by renal impairment, dose adjustment is necessary. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose for adults is 5 mg (10 ml of this syrup). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May take with or without food
Food does not significantly affect absorption.
Alcohol
Avoid
May increase drowsiness and impair performance.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of l citrid 2.5mg syrup

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. If persistent, consult your doctor.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.
Dry mouth (Common (2-5%))
Stay hydrated by drinking water. Chewing sugar-free gum may help.
Headache (Common (2-5%))
Usually resolves on its own. If severe or persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of the face, lips, or throat, or a severe rash.
Irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you notice palpitations or irregular heartbeat.
Severe skin reactions (Rare (<0.1%))
Stop the medicine and seek medical help if you develop a severe rash, blistering, or peeling skin.

⚠️ Rare Side Effects

Agitation
Consult your doctor if this occurs.
Confusion
Consult your doctor if this occurs.
Vision changes
Consult your doctor if this occurs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
CNS depressants Major
Ritonavir Moderate
Theophylline Moderate

🚨 Major Interactions

  • CNS depressants (e.g., alcohol, sedatives, opioids)

⚡ Moderate Interactions

  • Ritonavir
  • Theophylline

🍷 Alcohol Interaction

Alcohol may enhance the sedative effects of this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levocetirizine or any component of the formulation","Severe renal impairment (creatinine clearance < 10 mL/min)","Children under 6 years of age (for this syrup formulation, consult physician for appropriate use)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in elderly patients who may be more sensitive to side effects.","Do not exceed the recommended dose.","Consult a doctor if symptoms persist or worsen."]

🤱 Lactation Safety

Levocetirizine is excreted in breast milk in small amounts. Caution is advised when used during breastfeeding. Consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may cause drowsiness, agitation, or restlessness. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if ingestion is recent.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have kidney disease, liver disease, or any other medical conditions. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine as it can increase drowsiness. This medicine may interact with other medications, so always provide a complete list of medicines you are taking to your healthcare provider. Do not exceed the recommended dose. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sedative effects of this medicine. Dose adjustment based on renal function is recommended. Monitor for drowsiness and falls.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It is generally considered safe but should be used under medical supervision.

🏥 Post-Surgery Considerations

This medicine may be used after surgery for allergic reactions, but consult your surgeon. It may interact with other medications used post-operatively.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergy triggers.
🥗
Keep windows closed during high pollen seasons.
😴
Use air purifiers to reduce indoor allergens.
💧
Maintain a healthy diet rich in fruits and vegetables.
🧘
Get adequate sleep to support immune health.

🏋️ Exercise Considerations

This medicine may cause drowsiness, so avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Stay hydrated.
Include anti-inflammatory foods like omega-3 fatty acids.
Avoid known food allergens.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is advisable to take it in the evening to minimize daytime sedation. Consult your doctor if your work requires high alertness.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms improve, your doctor may advise tapering or stopping.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe, but it may cause tolerance or reduced effectiveness in some individuals. Regular monitoring of renal function is advised for patients with kidney disease. Consult your doctor for periodic review.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Avoiding allergens can reduce the need for medication.

Evidence: Well-established
Nasal saline irrigation

Helps relieve nasal congestion.

Evidence: Well-established
Immunotherapy

Allergy shots can provide long-term relief.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, consult your doctor before vaccination if you are on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations regarding carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with seasonal allergies
She started taking this medicine as prescribed for her sneezing and runny nose. Within an hour, her symptoms improved significantly. She experienced mild drowsiness initially but it subsided after a few days. She advises taking it in the evening to avoid daytime sleepiness.
💡 Lesson: This medicine provides rapid relief from allergy symptoms, but timing the dose can help manage drowsiness.
👤 A 45-year-old man with chronic hives
He was prescribed this medicine for chronic urticaria. After taking it regularly for a week, his itching and hives reduced dramatically. He emphasizes the importance of not missing doses and avoiding alcohol, which worsened his drowsiness.
💡 Lesson: Consistent use and avoiding alcohol enhance the effectiveness and tolerability of this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 1 hour after taking a dose.

Q: Can I take it with food?

A: Yes, it can be taken with or without food.

Q: Is it safe for children?

A: It is safe for children aged 2 years and older, but the dose depends on age and weight. Consult a pediatrician.

Q: What are the common side effects?

A: Common side effects include drowsiness, fatigue, dry mouth, and headache.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for l citrid 2.5mg syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a steroid.
    Fact: This medicine is an antihistamine, not a steroid.
  • Myth: It can be used for common cold.
    Fact: It is not effective for common cold unless there is an allergic component.
  • Myth: It causes immediate weight gain.
    Fact: Weight gain is not a common side effect.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine syrup

Brand Alternatives

  • Levocet
  • Xyzal
  • Levorid
  • Teczine

📊 Comparison with Similar Medicines

[{"medicine":"Levocetirizine","class":"Third-generation antihistamine","sedation":"Low","duration":"24 hours"},{"medicine":"Cetirizine","class":"Second-generation antihistamine","sedation":"Moderate","duration":"24 hours"},{"medicine":"Loratadine","class":"Second-generation antihistamine","sedation":"Low","duration":"24 hours"}]

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