Panthor DX Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of face, lips, or throat
- Severe dizziness or fainting
- Hallucinations or confusion
- Irregular heartbeat or chest pain
- Blood in cough or vomit
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is kufma syrup used for?
This medicine is a combination cough syrup containing dextromethorphan (cough suppressant) and guaifenesin (expectorant). It is used to relieve dry cough and chest congestion. The usual adult dose is 10 ml every 4-6 hours, not exceeding 60 ml in 24 hours. It should not be used in children under 12 years without medical advice.
- Generic Name: Dextromethorphan Hydrobromide (10mg/5ml) + Guaifenesin (100mg/5ml)
- Manufacturer: Wings Biotech Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kufma syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सूखी खांसी और छाती में जकड़न के अस्थायी राहत के लिए उपयोग की जाती है। इसमें डेक्सट्रोमेथोर्फन और गुआइफेनेसिन होते हैं, जो खांसी को कम करने और बलगम को पतला करने में मदद करते हैं। यह सर्दी-जुकाम या हल्के श्वसन संक्रमण के कारण होने वाली खांसी में प्रभावी है। यह दवा 12 वर्ष से अधिक उम्र के बच्चों और वयस्कों के लिए है, लेकिन डॉक्टर की सलाह के बिना 12 वर्ष से कम बच्चों को न दें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, जी मिचलाना, उल्टी और पेट में असहजता शामिल हैं। कुछ लोगों को सिरदर्द या बेचैनी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, या मतिभ्रम हो सकता है। अगर ऐसा कुछ हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। शराब का सेवन न करें। गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। निर्धारित खुराक से अधिक न लें। अगर खांसी 7 दिनों से अधिक रहती है, तो डॉक्टर से मिलें।
💊 kufma syrup Uses & Benefits
[{"condition":"Dry cough","description":"This medicine helps suppress dry, irritating cough by acting on the cough center in the brain.","evidence":"Well-established"},{"condition":"Productive cough with thick mucus","description":"The guaifenesin component helps thin and loosen mucus, making it easier to expel.","evidence":"Well-established"},{"condition":"Common cold with cough","description":"Provides symptomatic relief of cough and chest congestion associated with the common cold.","evidence":"Well-established"},{"condition":"Upper respiratory tract infections","description":"Used for temporary relief of cough due to minor throat and bronchial irritation.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cough in palliative care","description":"Sometimes used off-label for cough relief in palliative care settings, but only under medical supervision.","evidence":"Limited"}]
Primary treatment for: Cough
Also treats: Common cold, Upper respiratory tract infection, Bronchitis
📋 Drug Information
| Generic Name(s) | Dextromethorphan Hydrobromide (10mg/5ml) + Guaifenesin (100mg/5ml) |
| Brand Name | kufma syrup |
| Manufacturer | Wings Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate unless specified on the label. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Dextromethorphan hydrobromide acts on the central nervous system by binding to sigma-1 receptors and NMDA receptors, and it also suppresses the cough reflex by affecting the medullary cough center. It does not have analgesic or addictive properties at usual doses. Guaifenesin is an expectorant that works by increasing the volume and reducing the viscosity of respiratory tract secretions, which helps in the removal of mucus from the airways. Together, they provide cough suppression and mucus clearance.
Mechanism Steps
💡 How to Take kufma syrup
Strength: Each 5 ml contains Dextromethorphan Hydrobromide 10 mg and Guaifenesin 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 ml (2 teaspoons) every 4 to 6 hours as needed, not to exceed 60 ml in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Follow your doctor's instructions carefully. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Dose adjustment may be needed in patients with kidney disease. Consult your doctor for guidance. |
| Hepatic Impairment | Dose adjustment may be needed in patients with liver disease. Consult your doctor for guidance. |
| Maximum Daily Dose | The maximum daily dose for adults is 60 ml in 24 hours. Do not exceed this limit. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kufma syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| SSRIs | Major | |
| CYP2D6 inhibitors | Major | |
| Alcohol | Moderate | |
| Benzodiazepines | Moderate | |
| Opioids | Moderate | |
| Antihistamines | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- SSRIs (e.g., fluoxetine, paroxetine)
- CYP2D6 inhibitors (e.g., quinidine, terbinafine)
⚡ Moderate Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Antihistamines (e.g., diphenhydramine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of respiratory depression. It may also worsen stomach upset.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to dextromethorphan, guaifenesin, or any component of the formulation.","Concurrent use with MAO inhibitors or within 14 days of stopping an MAO inhibitor.","Children under 12 years of age (unless directed by a doctor).","Chronic cough associated with smoking, asthma, or emphysema.","Cough accompanied by excessive secretions."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Avoid driving or operating machinery until you know how this medicine affects you.","Do not use for persistent or chronic cough unless directed by a doctor.","Consult a doctor if cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache.","Use with caution in patients with liver or kidney disease.","Use with caution in patients with a history of drug abuse or addiction.","Do not use in children under 12 years without medical advice."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, dizziness, nausea, vomiting, hallucinations, rapid heartbeat, and respiratory depression. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote for dextromethorphan or guaifenesin overdose. Gastric lavage may be considered if taken recently. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have a history of liver or kidney disease, asthma, chronic bronchitis, or if you are pregnant or breastfeeding. Do not take this medicine with alcohol or other cough and cold medicines without consulting a doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness. Do not exceed the recommended dose or duration of treatment. If your cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache, stop using this medicine and consult a doctor. Keep this medicine out of reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning to become pregnant or are pregnant.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may cause dry mouth or interact with anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or drowsy. Light activity is fine if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if your cough persists for more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. Do not stop abruptly if you have been taking it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use may lead to tolerance, dependence, or masking of underlying conditions. If cough persists beyond 7 days, consult a doctor for further evaluation.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and soothe airways.
Evidence: Well-establishedSoothes throat and reduces cough.
Evidence: Well-establishedHelps clear nasal congestion.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor if you are due for any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of the prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, continue with your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 15-30 minutes after taking it.
A: Consult your doctor before taking with other cold medicines to avoid interactions.
A: It is not recommended for children under 12 years without medical advice.
A: Consult your doctor before use during pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for kufma syrup
View AllAlternative brands with exact same active ingredient:
-
kufril-sf syrupMed Manor Organics Pvt Ltd ₹37.50 23.1% CHEAPER
-
coldnem syrupNemi Pharmaceuticles ₹46.88 3.8% CHEAPER
-
dexef q syrupZota Health care Ltd ₹48.00 1.5% CHEAPER
-
depcof plus syrupVrinda Life ₹55.10 13% COSTLIER
-
riotuss syrupOrion Lifesciences ₹56.95 16.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for temporary relief of dry cough and chest congestion. It does not treat the underlying cause, such as infection or asthma. - Myth: It is safe to take this medicine for a long time.
Fact: Prolonged use is not recommended. If cough persists beyond 7 days, consult a doctor. - Myth: More medicine means faster relief.
Fact: Taking more than the recommended dose can lead to serious side effects. Always follow the dosage instructions.
🔄 Alternative Options
Generic Alternatives
- Dextromethorphan + Guaifenesin syrup (generic)
Brand Alternatives
- Panthor DX Syrup