Hydroxyzine 25mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular or fast heartbeat
- Fainting or severe dizziness
- Difficulty breathing or swelling of face, lips, or throat
- Seizures
- Yellowing of skin or eyes
- Unusual bruising or bleeding
- Severe drowsiness or confusion
If experiencing severe symptoms, call emergency services immediately.
What is krust 25mg tablet used for?
This medicine is an antihistamine used to treat allergic skin reactions like itching and hives, and for short-term anxiety. It works by blocking histamine and calming the nervous system. It causes drowsiness, so avoid driving. Take it exactly as prescribed.
- Generic Name: Hydroxyzine (25mg)
- Manufacturer: Bio Sciences Pharmakon
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 krust 25mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा हाइड्रॉक्सिज़िन 25 मिलीग्राम की टैबलेट है, जिसका उपयोग एलर्जी के कारण होने वाली खुजली, पित्ती, और त्वचा की एलर्जी के इलाज के लिए किया जाता है। यह चिंता और तनाव को कम करने में भी मदद करती है और उल्टी जैसी समस्याओं में भी दी जा सकती है। यह दवा दिमाग में हिस्टामिन नामक पदार्थ को रोककर काम करती है, जिससे एलर्जी के लक्षण कम होते हैं और नींद आने जैसा आराम महसूस होता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना और थकान शामिल हैं। कुछ लोगों को सिरदर्द या धुंधली दृष्टि भी हो सकती है। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि दिल की धड़कन अनियमित हो, साँस लेने में तकलीफ हो, या चक्कर आकर बेहोशी हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएँ। इस दवा को लेने के बाद नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। दवा को बच्चों से दूर, ठंडी और सूखी जगह पर रखें।
💊 krust 25mg tablet Uses & Benefits
[{"condition":"Allergic skin conditions (urticaria, itching)","description":"This medicine relieves itching and hives by blocking histamine H1 receptors.","evidence":"Well-established"},{"condition":"Anxiety (short-term)","description":"Used for short-term management of anxiety and tension due to its sedative effects.","evidence":"Well-established"},{"condition":"Pre-operative sedation","description":"Sometimes given before surgery to help calm patients and reduce anxiety.","evidence":"Well-established"},{"condition":"Nausea and vomiting","description":"May be used to help control nausea and vomiting, though not a first-line agent.","evidence":"Limited"}]
Off-label uses: [{"condition":"Insomnia","description":"Occasionally prescribed off-label for short-term sleep aid due to sedative effects.","evidence":"Limited"},{"condition":"Pruritus in liver disease","description":"Sometimes used to relieve itching associated with cholestasis.","evidence":"Limited"}]
Primary treatment for: Allergic skin conditions and anxiety
Also treats: Nausea and vomiting, Pre-operative anxiety
📋 Drug Information
| Generic Name(s) | Hydroxyzine (25mg) |
| Brand Name | krust 25mg tablet |
| Manufacturer | Bio Sciences Pharmakon |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | H1 Antihistaminics (First Generation) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively blocking histamine H1 receptors in the central nervous system and peripheral tissues. By blocking these receptors, it prevents histamine from causing allergic symptoms such as itching, sneezing, and vasodilation. Additionally, it suppresses activity in certain brain areas, leading to sedation and reduction of anxiety.
Mechanism Steps
💡 How to Take krust 25mg tablet
Strength: 25 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose for anxiety is 25 to 100 mg taken 3 to 4 times daily. For itching, 25 mg may be taken 3 to 4 times daily. For pre-operative sedation, 50 to 100 mg is given the night before and 1 hour before surgery. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative and anticholinergic effects. Start with a lower dose and titrate slowly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with severe renal impairment. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 100 mg for adults, but this may vary based on indication and patient factors. Always follow your doctor's advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of krust 25mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CNS depressants | Major | |
| QT-prolonging drugs | Major | |
| Anticholinergics | Moderate | |
| MAO inhibitors | Moderate | |
| Antihypertensives | Minor |
🚨 Major Interactions
- CNS depressants (e.g., opioids, benzodiazepines, alcohol)
- QT-prolonging drugs (e.g., amiodarone, sotalol, certain antipsychotics)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., benztropine, oxybutynin)
- MAO inhibitors
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness, dizziness, and impair your ability to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to hydroxyzine or any component of the formulation","Porphyria","Prolonged QT interval or family history of long QT syndrome","Severe liver disease","Concurrent use with QT-prolonging drugs"]
⚠️ Warnings & Precautions
["May cause significant drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","May prolong QT interval; use with caution in patients with cardiac disease.","Not recommended for long-term use without medical supervision.","Consult doctor before use in pregnancy or breastfeeding."]
🤱 Lactation Safety
This medicine passes into breast milk and may cause drowsiness in the infant. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, confusion, seizures, and respiratory depression. Seek emergency medical attention immediately. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause significant drowsiness. Do not drink alcohol while taking this medicine because it can increase sedation and impair your ability to think clearly. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all other medicines you are taking, especially those that affect heart rhythm or cause drowsiness. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. They may experience increased confusion, dizziness, and risk of falls. Lower doses are recommended, and close monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used before surgery for sedation. After surgery, it may interact with other sedatives. Inform your surgeon and anesthesiologist about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with sedatives or anesthetics used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may affect your coordination. Avoid strenuous exercise or activities that require alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause significant drowsiness, which may impair your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is best to avoid such activities until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor, especially if you have been taking it regularly. Your doctor will advise you on how to taper the dose if needed.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, dependence, and increased risk of side effects such as cognitive impairment and falls, especially in the elderly. Regular monitoring by a doctor is recommended if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be effective for anxiety without medication side effects.
Evidence: Well-establishedIdentifying and avoiding allergens can reduce the need for antihistamines.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before any vaccination if you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of doses. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it by mouth.
A: It is generally used short-term. Long-term use should be discussed with your doctor.
A: Pediatric dosing is not established from available information. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for krust 25mg tablet
View AllAlternative brands with exact same active ingredient:
-
hydrogn 25 tabletZeelab Pharmacy Pvt Ltd ₹8.00 57.9% CHEAPER
-
d rax 25mg tabletD D Pharmaceuticals ₹14.00 26.3% CHEAPER
-
drhyd 25mg tabletDR Best pharmaceuticals Pvt Ltd ₹14.06 26% CHEAPER
-
geozen 25mg tabletDermawin Pharmaceuticals ₹14.06 26% CHEAPER
-
zoxin 25mg tabletPifer Pharmaceuticals Pvt Ltd ₹14.06 26% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a sleeping pill.
Fact: It is an antihistamine with sedative effects, but it is not approved as a primary sleep aid. - Myth: It is safe to drive after taking this medicine.
Fact: It can cause significant drowsiness and impair driving ability. Avoid driving until you know how it affects you.
🔄 Alternative Options
Generic Alternatives
- Hydroxyzine 25 mg tablet
Brand Alternatives
- Atarax 25 mg tablet
- Vistaril 25 mg tablet