klarim 125 dt tablet pineapple - Clarithromycin (125mg) medicine

eclarin 125mg tablet (Clarithromycin): Comprehensive Medicine Guide

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🏭 Morepen Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe or persistent diarrhea, especially with blood or mucus
  • Yellowing of the skin or eyes, dark urine, or severe abdominal pain
  • Irregular heartbeat, palpitations, dizziness, or fainting
  • Severe skin rash, blistering, or peeling
  • Unusual bleeding or bruising
  • Decreased urine output or swelling in the legs

If experiencing severe symptoms, call emergency services immediately.

What is klarim 125 dt tablet pineapple used for?

This medicine contains clarithromycin, a macrolide antibiotic used to treat various bacterial infections. It works by stopping bacteria from making proteins they need to survive. It is taken orally, usually every 12 hours, and must be prescribed by a doctor.

  • Generic Name: Clarithromycin (125mg)
  • Manufacturer: Morepen Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 klarim 125 dt tablet pineapple के बारे में (Hindi Summary)

उपयोग: यह दवा क्लैरिथ्रोमाइसिन 125 मिलीग्राम की एक एंटीबायोटिक गोली है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र के संक्रमण, त्वचा के संक्रमण, और एच. पाइलोरी के इलाज में मदद करती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द और स्वाद में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, पीलिया, या गंभीर दस्त हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। शराब का सेवन न करें। एंटासिड के साथ इस दवा को लेने से बचें, कम से कम 2 घंटे का अंतराल रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 klarim 125 dt tablet pineapple Uses & Benefits

[{"condition":"Community-acquired respiratory tract infections","description":"Used to treat certain bacterial infections of the upper and lower respiratory tract, including pharyngitis, sinusitis, bronchitis, and pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Prescribed for uncomplicated skin infections such as cellulitis, impetigo, and erysipelas when caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Helicobacter pylori eradication","description":"Used as part of combination regimens to eradicate Helicobacter pylori in patients with peptic ulcer disease.","evidence":"Well-established"},{"condition":"Mycobacterium avium complex (MAC) infection prevention","description":"Used to prevent disseminated MAC infection in patients with advanced HIV infection.","evidence":"Well-established"},{"condition":"Acute otitis media","description":"Sometimes used to treat middle ear infections in patients allergic to penicillin, when caused by susceptible bacteria.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Lyme disease","description":"Occasionally used as an alternative in patients who cannot take standard antibiotics, but not first-line.","evidence":"Limited"},{"condition":"Mycobacterium abscessus infections","description":"Sometimes included in combination regimens for difficult-to-treat nontuberculous mycobacterial infections.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Helicobacter pylori infection, Mycobacterium avium complex infection

📋 Drug Information

Generic Name(s)Clarithromycin (125mg)
Brand Nameklarim 125 dt tablet pineapple
ManufacturerMorepen Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolides
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf LifeThe shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the packaging for the exact expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed and complete the full course, even if you feel better after a few days.
2
Take with food if it upsets your stomach, but avoid taking it with antacids containing aluminum or magnesium within 2 hours.
3
Inform your doctor about all other medicines you are taking, especially blood thinners, statins, and diabetes medicines, as interactions can be serious.
4
Avoid alcohol while taking this medicine to reduce the risk of liver problems and stomach irritation.
5
If you develop severe diarrhea, yellowing of the eyes or skin, or an irregular heartbeat, seek medical attention immediately.
6
Do not use this medicine to treat viral infections like the common cold or flu, as it will not help and may cause harm.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Persistent cough with fever
This medicine is commonly prescribed for bacterial respiratory infections.
Likely Use
✅
Skin redness and swelling
This medicine may be used for bacterial skin infections.
Likely Use
❌
Runny nose and sneezing
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is approximately 50% to 55% due to first-pass metabolism. Food may slightly delay absorption but does not significantly affect the overall extent of absorption.
DistributionThis medicine is widely distributed throughout the body, including into the lungs, skin, and soft tissues. It achieves high intracellular concentrations, which is useful for treating intracellular pathogens. It also penetrates into middle ear fluid and tonsillar tissue.
Protein BindingThis medicine is approximately 70% to 80% bound to plasma proteins, primarily to alpha-1-acid glycoprotein and albumin.
MetabolismThis medicine is extensively metabolized in the liver, primarily by the cytochrome P450 3A4 enzyme, to an active metabolite known as 14-hydroxyclarithromycin. This metabolite has antibacterial activity and contributes to the overall effect.
Half-LifeThe elimination half-life of this medicine is approximately 3 to 4 hours in healthy adults, but it may be prolonged in patients with renal impairment.
ExcretionThis medicine and its metabolites are excreted primarily in the urine (about 20% to 40% as unchanged drug) and in the feces (about 30% to 40%).
BioavailabilityThe oral bioavailability of this medicine is approximately 50% to 55%.
Onset of ActionThe onset of action for this medicine is not immediate; it typically takes several hours to start inhibiting bacterial growth. Clinical improvement in symptoms may be seen within 1 to 2 days of starting treatment.
Peak Plasma TimePeak plasma concentrations of this medicine are reached approximately 2 to 3 hours after oral administration.
Duration of ActionThe antibacterial effect of this medicine lasts for about 12 to 24 hours after a dose, depending on the susceptibility of the bacteria and the dosing regimen.

How It Works

This medicine works by binding to the 50S ribosomal subunit of susceptible bacteria and blocking the translocation step of protein synthesis. By preventing the bacteria from building essential proteins, it stops their growth and multiplication, allowing the body's immune system to clear the infection. This action is primarily bacteriostatic, meaning it inhibits bacterial growth rather than directly killing the bacteria, although it can be bactericidal against some organisms at higher concentrations.

Mechanism Steps

1
Entry into bacterial cell: This medicine penetrates the bacterial cell wall and enters the cytoplasm of susceptible bacteria.
2
Binding to 50S ribosomal subunit: It binds reversibly to the 50S subunit of the bacterial ribosome, specifically near the peptidyl transferase center.
3
Blocking protein synthesis: By binding to the 50S subunit, it prevents the translocation of tRNA and inhibits the elongation of the growing polypeptide chain.
4
Inhibition of bacterial growth: Without essential proteins, the bacteria cannot grow or multiply, and the infection is controlled.
5
Immune clearance: The body's immune system can then eliminate the weakened bacteria, helping to resolve the infection.

💡 How to Take klarim 125 dt tablet pineapple

Strength: This medicine is available as an immediate-release tablet containing 125 mg of clarithromycin.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a full glass of water.
3You may take it with or without food, but taking it with food may reduce stomach upset.
4Do not crush, chew, or break the tablet unless instructed by your doctor.
5Take at evenly spaced intervals as directed.
6Complete the full course of treatment even if you feel better.
7Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose of this medicine for most respiratory and skin infections is 250 mg to 500 mg every 12 hours for 7 to 14 days, depending on the severity and type of infection. For Helicobacter pylori eradication, it is used as part of a combination regimen, often 500 mg twice daily. For Mycobacterium avium complex prevention, the dose is 500 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially cardiac arrhythmias and hearing loss. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance less than 30 mL/min), the dose of this medicine should be reduced by half or the dosing interval extended. Consult a doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, this medicine should be used with caution. Dose adjustment may be necessary. Monitor liver function closely.
Maximum Daily DoseThe maximum recommended daily dose of this medicine for adults is 1000 mg (1 gram) per day, but this may vary based on the indication and clinical judgment.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit juice
Avoid
May increase drug levels and side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of klarim 125 dt tablet pineapple

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, contact your doctor immediately.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe or persistent, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult your doctor if it persists.
Altered taste (Common (5-10%))
This usually goes away after treatment ends. Inform your doctor if it bothers you.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, or throat, difficulty breathing, or a severe rash.
Liver toxicity (Rare (<0.1%))
Contact your doctor right away if you notice yellowing of the skin or eyes, dark urine, or severe abdominal pain.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop severe, persistent diarrhea, especially if it contains blood or mucus.
Irregular heart rhythm (QT prolongation) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, dizziness, or fainting.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you develop severe upper abdominal pain that radiates to your back.
Seizures
Call emergency services if a seizure occurs.
Hearing loss
Report any hearing changes to your doctor promptly.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Simvastatin Major
Ergotamine Major
Cisapride Major
Digoxin Moderate
Carbamazepine Moderate
Theophylline Moderate
Oral hypoglycemics Moderate
Rifampicin Moderate
Antacids Minor

🚨 Major Interactions

  • Ergotamine and dihydroergotamine
  • Cisapride
  • Pimozide
  • Terfenadine
  • Warfarin
  • Simvastatin and lovastatin

⚡ Moderate Interactions

  • Digoxin
  • Carbamazepine
  • Theophylline
  • Oral hypoglycemics
  • Rifampicin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase the risk of stomach irritation, liver problems, and may worsen side effects such as nausea and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to clarithromycin or other macrolide antibiotics","Concomitant use with ergotamine or dihydroergotamine","Concomitant use with cisapride, pimozide, or terfenadine","History of QT prolongation or ventricular arrhythmias","Severe hepatic impairment combined with renal impairment"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease; monitor liver function.","Use with caution in patients with kidney disease; dose adjustment may be needed.","May cause QT prolongation; avoid in patients with risk factors.","Can cause Clostridioides difficile-associated diarrhea; report persistent diarrhea.","May interact with many drugs; review all concomitant medications.","Not effective against viral infections; do not use for colds or flu.","Complete the full course as prescribed to prevent resistance."]

🤱 Lactation Safety

This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but monitoring the infant for diarrhea, thrush, or rash is advised. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine may cause severe nausea, vomiting, diarrhea, and abdominal pain. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis does not effectively remove clarithromycin from the blood.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you start feeling better, because doing so can allow the infection to return and may contribute to antibiotic resistance. Swallow the tablet whole with a full glass of water. You may take this medicine with or without food, but taking it with food may help reduce stomach upset. Avoid alcohol while taking this medicine, as it can worsen stomach irritation and may increase the risk of liver problems. Do not take antacids that contain aluminum or magnesium within two hours of taking this medicine, because they can reduce how well it is absorbed. Inform your doctor about all other medicines, supplements, and herbal products you are using, especially blood thinners, cholesterol medicines, diabetes medicines, and migraine medicines. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before taking this medicine. Keep this medicine out of the reach of children and store it at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects such as cardiac arrhythmias, hearing loss, and liver problems. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe when clearly needed, but the benefits and risks should be discussed.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with certain anesthetic agents and other medications used during surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure, as it may interact with certain medications used in dentistry and can affect bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Complete the full course of antibiotics as prescribed.
🥗
Stay well hydrated to help your body fight the infection.
😴
Get plenty of rest to support your immune system.
💧
Eat a balanced diet rich in fruits and vegetables.
🧘
Practice good hygiene to prevent the spread of infection.
🌞
Avoid alcohol while taking this medicine.

🏋️ Exercise Considerations

This medicine may cause dizziness or fatigue in some people. Avoid strenuous exercise if you feel unwell or dizzy. Light activity is fine if you feel up to it.

🥗 Diet Recommendations

Stay well hydrated with water and clear fluids.
Include probiotic-rich foods like yogurt to help maintain gut health.
Avoid spicy and fatty foods if you have stomach upset.
Eat small, frequent meals if you experience nausea.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their normal daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to treatment failure and antibiotic resistance. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not usually recommended unless for specific conditions like Mycobacterium avium complex prevention. Prolonged use can increase the risk of antibiotic resistance, liver problems, and Clostridioides difficile-associated diarrhea. Regular monitoring of liver and kidney function may be needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Azithromycin

Another macrolide antibiotic that may be used as an alternative.

Evidence: Well-established
Amoxicillin

A penicillin antibiotic that may be used for susceptible infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor, as antibiotics generally do not affect vaccine efficacy but the underlying infection may be a consideration.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, adjust dosing times gradually, but consult your doctor for specific advice. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a persistent cough and fever
He was diagnosed with bacterial bronchitis and prescribed this medicine. He took it with food to avoid stomach upset and completed the 10-day course. His cough and fever improved within 3 days, and he felt back to normal by the end of the week.
💡 Lesson: Taking the full course as prescribed and with food helps ensure effectiveness and reduces side effects.
👤 A 50-year-old woman with a skin infection
She was prescribed this medicine for cellulitis. She initially experienced nausea, but after taking it with meals, the nausea subsided. She completed the 7-day course and the infection cleared completely.
💡 Lesson: Taking this medicine with food can minimize stomach upset and improve tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1 to 2 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for klarim 125 dt tablet pineapple

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure the common cold.
    Fact: This medicine is not effective against viral infections like the common cold. It only works on bacterial infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: Clarithromycin is safe to take with any other medicine.
    Fact: This medicine can interact with many other medicines, some seriously. Always inform your doctor about all medicines you take.

🔄 Alternative Options

Generic Alternatives

  • Clarithromycin 125 mg tablet

Brand Alternatives

  • eclarin 125mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"eclarin 125mg tablet","class":"Macrolide antibiotic","half_life":"3-4 hours","dosing":"Twice daily","notes":"This medicine."},{"medicine":"Azithromycin","class":"Macrolide antibiotic","half_life":"68 hours","dosing":"Once daily","notes":"Longer half-life, different dosing."}]

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