Menadione 10mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, swelling of the face, lips, or throat, or a sudden drop in blood pressure.
- Severe abdominal pain, vomiting blood, or black, tarry stools.
- Yellowing of the skin or eyes, dark urine, or severe fatigue.
- Unusual bleeding that does not stop, such as nosebleeds or bleeding gums.
- In newborns: increased sleepiness, poor feeding, high-pitched cry, or yellowing of the skin.
- Chest pain, fast heartbeat, or fainting after the injection.
- Severe pain, redness, or pus at the injection site.
If experiencing severe symptoms, call emergency services immediately.
What is kevit 10mg injection used for?
This medicine is a synthetic vitamin K injection used to treat or prevent bleeding caused by vitamin K deficiency. It helps the liver produce clotting factors. It is given by a healthcare professional and is not recommended for newborns due to safety risks.
- Generic Name: Menadione (10mg)
- Manufacturer: T.Walker's Pharmceuticals Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kevit 10mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा मेनाडियोन का इंजेक्शन है, जो विटामिन K का एक सिंथेटिक रूप है। यह शरीर में खून के थक्के बनाने वाले कारकों को बनाने में मदद करती है। इसका उपयोग विटामिन K की कमी के कारण होने वाले रक्तस्राव को रोकने या इलाज करने के लिए किया जाता है। यह नवजात शिशुओं में रक्तस्राव को रोकने के लिए भी दिया जा सकता है, लेकिन सुरक्षा कारणों से अब इसके बजाय विटामिन K1 को प्राथमिकता दी जाती है। यह दवा डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जाती है। इसे खुद से न लगाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन, जी मिचलाना, और स्वाद में बदलाव शामिल हैं। कभी-कभी चेहरे पर गर्मी लगना, पसीना आना या दिल की धड़कन तेज हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें एलर्जी की प्रतिक्रिया, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और रक्तचाप में अचानक गिरावट शामिल हो सकती है। नवजात शिशुओं में यह दवा खून की कमी और पीलिया का कारण बन सकती है। अगर आपको असामान्य रक्तस्राव, चोट लगने पर नील, आंखों या त्वचा का पीलापन, या गहरे रंग का पेशाब दिखे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या गर्भधारण की योजना बना रही हैं, तो डॉक्टर को बताएं। अपनी सभी दवाओं, खासकर खून पतला करने वाली दवाओं के बारे में डॉक्टर को जानकारी दें। इस दवा के दौरान शराब न पिएं। इंजेक्शन के बाद अगर चक्कर आएं या अस्वस्थ महसूस हो, तो वाहन न चलाएं। डॉक्टर के बताए अनुसार नियमित जांच कराएं। दवा को सही तापमान पर रखें और एक्सपायरी डेट देखें।
💊 kevit 10mg injection Uses & Benefits
[{"condition":"Vitamin K deficiency bleeding (VKDB) in newborns","description":"This medicine is used to prevent or treat bleeding in newborns who have low vitamin K levels, a condition that can cause serious bleeding in the first weeks of life.","evidence":"Well-established"},{"condition":"Vitamin K deficiency in adults","description":"It is used when adults have low vitamin K due to poor diet, malabsorption, liver disease, or long-term antibiotic use, leading to easy bruising or bleeding.","evidence":"Well-established"},{"condition":"Reversal of excessive anticoagulation with vitamin K antagonists","description":"This medicine can help restore normal clotting when a person on warfarin or similar blood thinners has too much anticoagulation and is bleeding or at high risk of bleeding.","evidence":"Well-established"},{"condition":"Obstructive jaundice or biliary disease","description":"People with blocked bile ducts may not absorb vitamin K properly from food, so this injection helps correct the deficiency and prevents bleeding.","evidence":"Well-established"},{"condition":"Malabsorption syndromes","description":"Conditions like celiac disease, cystic fibrosis, or short bowel syndrome can cause vitamin K deficiency, and this medicine helps replace it.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of bleeding in patients with liver cirrhosis","description":"Sometimes used to reduce bleeding risk in advanced liver disease, though evidence is limited and it may not fully correct clotting problems.","evidence":"Limited"},{"condition":"Management of hemorrhagic disease of the newborn beyond standard prophylaxis","description":"In some cases, repeated doses may be used for treatment rather than prevention, but this is guided by specialist care.","evidence":"Limited"}]
Primary treatment for: Vitamin K deficiency bleeding
Also treats: Obstructive jaundice, Malabsorption syndromes, Liver cirrhosis, Warfarin over-anticoagulation
📋 Drug Information
| Generic Name(s) | Menadione (10mg) |
| Brand Name | kevit 10mg injection |
| Manufacturer | T.Walker's Pharmceuticals Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Vitamins |
| Route of Administration | Parenteral (intramuscular or intravenous injection) |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Do not freeze. Keep in the original container until use. |
| Shelf Life | Not established from the available information. Refer to the product packaging for the expiry date. |
| WHO Guideline | The World Health Organization recommends vitamin K prophylaxis for all newborns to prevent vitamin K deficiency bleeding. However, the WHO specifically recommends phytonadione (vitamin K1) for this purpose, not menadione, due to safety concerns. This medicine is not the preferred form for newborn prophylaxis. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine provides a synthetic form of vitamin K that the liver uses to make several key clotting factors. Specifically, it acts as a cofactor for the enzyme gamma-glutamyl carboxylase, which adds carboxyl groups to glutamate residues on clotting factors II, VII, IX, and X, as well as proteins C and S. This carboxylation is necessary for these proteins to bind calcium and function properly in the clotting cascade. Without enough vitamin K, these factors remain inactive, leading to prolonged bleeding. By supplying menadione, this medicine helps restore the liver's ability to produce active clotting factors, thereby improving blood coagulation.
Mechanism Steps
💡 How to Take kevit 10mg injection
Strength: Injection: 10 mg per vial or ampoule (as menadione).
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the indication, severity of deficiency, age, weight, and liver function. For vitamin K deficiency bleeding in adults, a typical dose may range from 5 mg to 10 mg given intramuscularly or intravenously, but this can vary. For reversal of warfarin over-anticoagulation, doses may be higher and are determined by INR and bleeding status. Do not self-administer. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. In newborns, menadione is generally avoided due to the risk of hemolytic anemia and kernicterus; safer forms of vitamin K are preferred. Any use in children must be under strict medical supervision. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially if they have liver or kidney disease. Doses should be individualized by a clinician, and liver and kidney function should be monitored. There is no specific dose adjustment established from available information. |
| Renal Impairment | Dose adjustment in renal impairment is not established from the available information. Use with caution and monitor kidney function. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Dose adjustment in hepatic impairment is not established from the available information. Menadione is metabolized in the liver, so liver disease may affect its action and increase the risk of toxicity. Use with caution and monitor liver function. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | Not established from the available information. The maximum daily dose must be determined by a qualified clinician based on the patient's condition and response. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kevit 10mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Cefoperazone | Major | |
| Cholestyramine | Moderate | |
| Broad-spectrum antibiotics | Moderate | |
| Mineral oil | Minor | |
| Orlistat | Minor |
🚨 Major Interactions
- Warfarin and other vitamin K antagonists
- Cephalosporins with NMTT side chain (e.g., cefoperazone, cefotetan)
⚡ Moderate Interactions
- Broad-spectrum antibiotics
- Bile acid sequestrants (e.g., cholestyramine)
🍷 Alcohol Interaction
Alcohol can increase the risk of liver problems and bleeding. It may also reduce the effectiveness of this medicine because the liver is less able to produce clotting factors. It is best to avoid alcohol while receiving this medicine, especially if you have liver disease or are on blood thinners.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to menadione or any component of the injection","Severe liver disease with impaired synthetic function","Hemolytic anemia or a history of hemolytic reactions to vitamin K","Glucose-6-phosphate dehydrogenase (G6PD) deficiency, especially in newborns","Premature infants due to high risk of hemolytic anemia and kernicterus"]
⚠️ Warnings & Precautions
["This medicine should be given only by a healthcare professional.","Use with caution in patients with liver disease, kidney disease, or blood disorders.","Avoid in newborns, especially premature infants, due to risk of hemolytic anemia and jaundice.","Monitor INR closely if you are on warfarin or other blood thinners.","Do not use if the solution is discolored or contains particles.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol while receiving this medicine.","Report any signs of allergic reaction, bleeding, or jaundice immediately."]
🤱 Lactation Safety
It is not known whether menadione passes into breast milk in significant amounts. Because of the potential for serious side effects in a nursing infant, this medicine should be used during breastfeeding only if clearly needed and under medical supervision. Your doctor may recommend monitoring the baby for jaundice or unusual bleeding.
💊 Overdose Management
Overdose of menadione can cause severe hemolytic anemia, jaundice, and liver damage. There is no specific antidote. Treatment is supportive and may include blood transfusions, phototherapy for newborns with jaundice, and management of liver complications. If you suspect an overdose, seek emergency medical attention immediately.
⏰ Missed Dose
This medicine is given by a healthcare professional, so missed doses are unlikely. If you miss a scheduled injection, contact your doctor or clinic as soon as possible to reschedule. Do not attempt to self-administer a double dose.
Additional Safety Advice
This medicine must be given only by a healthcare professional. Do not attempt to self-inject. Before receiving this injection, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also inform your doctor about any allergies, liver disease, kidney disease, or blood disorders you have. If you are taking blood thinners such as warfarin, this medicine can change their effect, so your doctor may need to adjust your dose and monitor your blood clotting tests closely. Avoid alcohol while receiving this medicine, as it can worsen liver stress. Do not drive or operate heavy machinery immediately after the injection if you feel dizzy or unwell. Keep all follow-up appointments so your doctor can check your response to treatment. Store this medicine as directed by your pharmacist, and do not use it if the solution is discolored or contains particles.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially if they have liver or kidney disease. They may also be at higher risk of bleeding due to other medications or conditions. Doses should be individualized, and liver and kidney function should be monitored closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor. Menadione is not recommended during pregnancy unless clearly needed. Your doctor may switch you to a safer form of vitamin K if supplementation is necessary.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anesthesiologist about this medicine. It can affect clotting and may interact with blood thinners used during or after surgery. Your doctor will monitor your clotting status and adjust your treatment as needed.
🦷 Dental Procedures
Before any dental procedure, inform your dentist about this medicine. It can affect bleeding, especially if you are also on blood thinners. Your dentist may need to coordinate with your doctor to ensure your clotting is adequate before the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid contact sports or activities that can cause injury while you have a bleeding tendency. Once your vitamin K deficiency is corrected, you can gradually resume normal activities. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a clinic or hospital, and you can usually return to work the same day unless you feel dizzy or unwell. If you have a bleeding tendency, avoid jobs that involve a risk of injury until your condition is corrected. Driving is generally safe if you feel well, but avoid driving if you experience dizziness or other side effects.
🛑 When to Stop This Medicine
This medicine is given as a short course, and your doctor will decide when to stop based on your response and blood tests. Do not stop or change the schedule on your own. If you experience serious side effects, your doctor may stop the medicine immediately. Always consult your doctor before stopping any treatment.
📅 Long-Term Use Effects
Long-term use of menadione is not common because it is usually given as a short course to correct deficiency. However, repeated or high doses can increase the risk of hemolytic anemia, liver toxicity, and jaundice. If long-term therapy is needed, regular monitoring of blood counts, liver function, and clotting tests is essential. Your doctor will determine the duration of treatment based on your condition.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A safer alternative to menadione, especially for newborns and pregnant women.
Evidence: Well-establishedMay be used for mild deficiency when oral intake is possible and absorption is adequate.
Evidence: Well-establishedIncreasing intake of vitamin K-rich foods can help prevent deficiency in some cases.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine. No specific timing adjustments are required.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C).
❌ DON'T
Do not freeze.
✅ DO
Keep in the original container until use.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Protect from light and moisture.
❌ DON'T
Do not store in the bathroom.
✅ DO
Check the expiry date before use.
❌ DON'T
Do not use if the solution is discolored or contains particles.
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional, so you will not need to carry it yourself. If you are traveling and need to receive this injection, carry a copy of your prescription and medical records. Inform your doctor about your travel plans so they can coordinate care. If you are on warfarin, arrange for INR monitoring at your destination. Keep the medicine in its original packaging and store it at room temperature, away from direct sunlight. Check customs regulations if you need to carry the injection across borders.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: After intravenous injection, the effect on clotting factors begins within 1-2 hours, but measurable improvement in clotting tests may take 6-12 hours. After intramuscular injection, it may take a bit longer.
A: Menadione is not recommended for newborns, especially premature infants, because it can cause serious blood problems and jaundice. Safer forms of vitamin K, such as phytonadione, are preferred.
A: This medicine is not recommended during pregnancy unless clearly needed. It can cross the placenta and may harm the baby. Your doctor will decide if the benefits outweigh the risks.
A: Avoid alcohol, and inform your doctor about all other medicines you take, especially blood thinners. Do not drive if you feel dizzy after the injection.
A: Seek immediate medical help if you have difficulty breathing, swelling of the face or throat, severe bleeding, yellowing of the skin or eyes, or a sudden drop in blood pressure.
🤔 Common Patient Concerns
🔄 Substitutes for kevit 10mg injection
View AllAlternative brands with exact same active ingredient:
-
Tito-K 10mg InjectionTabq Therapeutics ₹5.63 77.4% CHEAPER
-
hars k 10mg injectionHarson Laboratories ₹10.17 59.2% CHEAPER
-
vita k 10mg injectionMedilife Health Sciences Pvt Ltd ₹14.06 43.6% CHEAPER
-
k-win 10mg injectionMercury Laboratories Ltd ₹40.22 61.5% COSTLIER
-
vitadione 10mg injectionCasca Remedies Pvt Ltd ₹42.19 69.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Menadione is the same as vitamin K1 and can be used interchangeably.
Fact: Menadione is a synthetic form of vitamin K (vitamin K3), while vitamin K1 is phytonadione. They are not the same, and menadione is not preferred for newborns due to safety concerns. - Myth: Vitamin K injection is only for babies.
Fact: Vitamin K injections are also used in adults with vitamin K deficiency, liver disease, or those on blood thinners who are bleeding. - Myth: You can take menadione orally instead of injection.
Fact: This product is an injection and must be given by a healthcare professional. Oral forms of vitamin K are different and may not be suitable for all patients. - Myth: Menadione injection can reverse any blood thinner.
Fact: Menadione only reverses vitamin K antagonists like warfarin. It does not reverse direct oral anticoagulants like dabigatran or rivaroxaban.
🔄 Alternative Options
Generic Alternatives
- Menadione injection
Brand Alternatives
- Hars K 10mg Injection