Bactiderm G Cream: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe burning, itching, or rash that worsens after application.
- Signs of an allergic reaction: swelling of face, lips, or throat, difficulty breathing.
- New or worsening skin infection (increased redness, pus, pain).
- Symptoms of systemic corticosteroid effects: rapid weight gain, rounding of face, increased thirst or urination.
- Signs of kidney or ear damage: decreased urine output, hearing loss, ringing in ears.
- Skin thinning, stretch marks, or visible blood vessels appearing on treated area.
If experiencing severe symptoms, call emergency services immediately.
What is ketopoz total cream used for?
This medicine is a topical cream containing clobetasol (a strong steroid) and gentamicin (an antibiotic). It is used to treat inflamed skin conditions that have become infected. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily. Do not use for more than 2 weeks without medical advice.
- Generic Name: Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w)
- Manufacturer: Farlex Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketopoz total cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें क्लोबेटासोल (एक शक्तिशाली स्टेरॉयड) और जेंटामाइसिन (एक एंटीबायोटिक) शामिल हैं। इसका उपयोग त्वचा की सूजन वाली बीमारियों जैसे एक्जिमा, डर्मेटाइटिस या सोरायसिस में होता है जब उनमें बैक्टीरियल संक्रमण भी हो जाता है। यह खुजली, लालिमा और सूजन को कम करता है और संक्रमण का इलाज करता है। इसे डॉक्टर के निर्देशानुसार प्रभावित त्वचा पर पतली परत में लगाएं। इसे आंखों, होठों या म्यूकस मेम्ब्रेन पर न लगाएं। बिना डॉक्टर की सलाह के 2 हफ्ते से ज्यादा इस्तेमाल न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, सूखापन या लालिमा शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में त्वचा का पतला होना, खिंचाव के निशान, रक्त वाहिकाओं का दिखना और बालों का बढ़ना शामिल है। लंबे समय तक उपयोग से शरीर में स्टेरॉयड के प्रभाव जैसे ब्लड शुगर बढ़ना, हाई ब्लड प्रेशर या कुशिंग सिंड्रोम हो सकता है। अगर आपको कोई असामान्य लक्षण दिखे तो डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का इस्तेमाल डॉक्टर के बताए अनुसार ही करें। प्रभावित त्वचा पर पतली परत लगाएं और धीरे से मलें। आंखों, होठों और म्यूकस मेम्ब्रेन से बचें। लगाने के बाद हाथ धो लें, जब तक कि हाथ ही इलाज वाला हिस्सा न हो। बिना डॉक्टर की सलाह के इसे चेहरे, बगल या जांघों पर लंबे समय तक न लगाएं। 2 हफ्ते से ज्यादा लगातार इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों में 12 साल से कम उम्र में बिना डॉक्टर की सलाह के इस्तेमाल न करें।
💊 ketopoz total cream Uses & Benefits
[{"condition":"Infected eczema","description":"This medicine reduces inflammation and treats bacterial infection in eczema lesions that have become infected.","evidence":"Well-established"},{"condition":"Infected dermatitis","description":"Used for contact dermatitis or atopic dermatitis with secondary bacterial infection.","evidence":"Well-established"},{"condition":"Infected psoriasis","description":"Helps control psoriasis plaques that have become infected with bacteria.","evidence":"Moderate"},{"condition":"Infected insect bites","description":"Reduces inflammation and prevents infection from scratching.","evidence":"Limited"}]
Off-label uses: [{"condition":"Discoid lupus erythematosus","description":"Sometimes used for localized skin lesions, but only under specialist supervision.","evidence":"Limited"},{"condition":"Lichen simplex chronicus","description":"May be used short-term for thickened, itchy skin patches with infection.","evidence":"Limited"}]
Primary treatment for: Infected inflammatory skin conditions
Also treats: Eczema, Dermatitis, Psoriasis
📋 Drug Information
| Generic Name(s) | Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w) |
| Brand Name | ketopoz total cream |
| Manufacturer | Farlex Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store below 30°C in a cool, dry place. Do not freeze. Keep the tube tightly closed when not in use. Protect from light. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a super-potent corticosteroid (clobetasol) and an aminoglycoside antibiotic (gentamicin). Clobetasol works by binding to glucocorticoid receptors inside skin cells, which leads to suppression of inflammatory proteins and immune cells, reducing redness, swelling, and itching. Gentamicin works by binding to bacterial ribosomes, causing them to produce faulty proteins and ultimately killing the bacteria. Together, they address both inflammation and infection.
Mechanism Steps
💡 How to Take ketopoz total cream
Strength: Cream containing clobetasol 0.05% w/w and gentamicin 0.1% w/w.
Dosage Information
| Adult Dosage | Apply a thin film of this medicine to the affected area of skin once or twice daily, as directed by your doctor. The frequency and duration depend on the condition being treated and your response. Do not use for more than 2 weeks continuously without medical advice. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 12 years unless prescribed by a specialist. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects of corticosteroids. Use with caution and for the shortest duration possible. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment for topical use. However, if used on large areas or for prolonged periods, systemic absorption of gentamicin may occur, and renal function should be monitored in patients with kidney disease. |
| Hepatic Impairment | No specific dose adjustment for topical use. Use with caution in patients with severe liver disease due to potential systemic absorption of clobetasol. |
| Maximum Daily Dose | The maximum daily dose depends on the area treated and the condition. Generally, do not exceed 50 grams per week of this cream without medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketopoz total cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other topical corticosteroids | Major | |
| Nephrotoxic drugs | Major | |
| CYP3A4 inhibitors | Moderate | |
| Live vaccines | Moderate |
🚨 Major Interactions
- Other topical corticosteroids
- Nephrotoxic or ototoxic drugs (e.g., amphotericin B, loop diuretics, vancomycin)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
- Live vaccines
🍷 Alcohol Interaction
No known interaction between alcohol and this topical medicine. However, alcohol may worsen certain skin conditions like psoriasis, so moderation is advised.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to clobetasol, gentamicin, or any component of the cream","Untreated bacterial, viral, or fungal skin infections (unless the infection is being treated)","Acne vulgaris, rosacea, perioral dermatitis","Application on the face, groin, or axillae unless directed by a doctor","Use in children under 12 years without specialist supervision","Ophthalmic use"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas or for prolonged periods without medical supervision.","Do not use under occlusive dressings unless directed.","May cause skin thinning; use lowest effective dose for shortest duration.","Systemic absorption can occur, especially with damaged skin or large areas.","Gentamicin may cause kidney or ear damage if absorbed systemically.","Consult doctor if condition worsens or does not improve after a few days.","Do not use for acne, rosacea, or viral infections.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known if clobetasol or gentamicin pass into breast milk in significant amounts after topical application. However, caution is advised. Do not apply to the breast area before breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, and signs of corticosteroid excess. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Use this medicine exactly as prescribed by your doctor. Apply a thin layer to the affected skin and rub it in gently. Do not cover the treated area with airtight dressings unless your doctor tells you to. Avoid contact with eyes, lips, and mucous membranes. Wash your hands thoroughly after applying, unless your hands are the treated area. Do not use this medicine on large areas of the body, on the face, underarms, or groin for more than a few days unless specifically directed. Do not use it for longer than the prescribed duration, as prolonged use increases the risk of side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine on children under 12 years without a doctor's advice. Keep this medicine out of reach of children. If you accidentally swallow this medicine, seek medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to skin thinning and systemic side effects from corticosteroids. Use the lowest effective dose for the shortest duration. Monitor blood pressure and blood sugar if used extensively.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical corticosteroids should be used with caution during pregnancy. Use only if clearly needed and for the shortest duration possible.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine on surgical wounds. It may delay wound healing and increase the risk of infection. Do not apply to surgical incisions unless specifically instructed.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist if you are using this medicine, especially if you have a history of corticosteroid use.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions while using this medicine. However, if you have a skin condition on areas that rub during exercise, take care to keep the area clean and dry. Avoid swimming in chlorinated pools if you have open skin lesions.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or allergic reaction, avoid these activities until you feel better. You can continue your normal daily activities, but avoid activities that cause excessive sweating or friction on the treated area.
🛑 When to Stop This Medicine
Stop using this medicine after the prescribed duration or when your doctor tells you to. If you notice signs of skin thinning, stretch marks, or worsening infection, stop and consult your doctor. Do not stop abruptly if you have been using it for a long time without consulting your doctor, as withdrawal may cause a flare-up.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to skin thinning, stretch marks, visible blood vessels, and increased hair growth. Systemic absorption may cause high blood sugar, high blood pressure, and Cushing's syndrome. Prolonged use of gentamicin can lead to kidney damage or hearing loss. Regular monitoring by a doctor is recommended if long-term use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help soothe and protect the skin, reducing the need for steroids.
Evidence: Well-establishedCan help prevent infection in minor skin conditions.
Evidence: ModerateFor chronic conditions like psoriasis, under specialist care.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction with vaccines. However, if you are using this medicine over large areas or for prolonged periods, it may suppress the immune system and affect vaccine response. Consult your doctor before receiving live vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (below 30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight. If traveling to a hot climate, keep it in a cool bag. Do not leave it in a car where temperatures can exceed 30°C. If you are crossing time zones, continue applying as per your usual schedule; topical application is not time-critical like oral medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice improvement in itching and redness within a few hours to days. Full effect may take up to a week. If no improvement after 7 days, consult your doctor.
A: No, unless specifically instructed by your doctor. The face is more sensitive and prone to side effects like thinning and stretch marks.
A: It is not recommended for children under 12 years unless prescribed by a specialist. Children are more susceptible to systemic side effects.
A: Consult your doctor before use. Topical corticosteroids should be used with caution during pregnancy, especially in large amounts or for prolonged periods.
A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
🤔 Common Patient Concerns
🔄 Substitutes for ketopoz total cream
View AllAlternative brands with exact same active ingredient:
-
clobate g creamNestor Pharmaceuticals ₹9.28 84.8% CHEAPER
-
zinclovil creamVilco Laboratories Pvt Ltd ₹10.29 83.1% CHEAPER
-
globet gm ointmentGalpha Laboratories Ltd ₹10.55 82.7% CHEAPER
-
eatan g creamA. Menarini India Pvt Ltd ₹11.38 81.3% CHEAPER
-
powergen creamGlenmark Pharmaceuticals Ltd ₹11.77 80.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: It is only for specific infected inflammatory skin conditions and should not be used for acne, rosacea, or viral infections. - Myth: More cream means faster healing.
Fact: Using more than prescribed increases the risk of side effects without providing extra benefit. - Myth: It is safe to use for months.
Fact: Prolonged use can cause skin thinning, stretch marks, and systemic effects. Use only as long as prescribed.
🔄 Alternative Options
Generic Alternatives
- Clobetasol and gentamicin cream (generic)
Brand Alternatives
- Bactiderm G Cream