Ketamine 50mg Injection: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe high blood pressure or chest pain
- Irregular or very fast heartbeat
- Difficulty breathing or slow breathing
- Severe hallucinations or panic attacks
- Signs of allergic reaction such as rash, swelling, or difficulty breathing
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is ketamax 50mg injection used for?
This medicine is a ketamine injection used for anaesthesia and pain relief in hospital settings. It works by blocking NMDA receptors in the brain, producing a dissociative state. It is given only by healthcare professionals.
- Generic Name: Ketamine (50mg)
- Manufacturer: Troikaa Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketamax 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा कीटामाइन का इंजेक्शन है, जिसका उपयोग अस्पताल में एनेस्थीसिया (बेहोशी) और तेज दर्द से राहत के लिए किया जाता है। यह मस्तिष्क में कुछ रिसेप्टर्स को ब्लॉक करके काम करती है, जिससे मरीज को दर्द महसूस नहीं होता और वह बेहोश हो जाता है। यह दवा केवल डॉक्टर या प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतिभ्रम, मतली, उल्टी, भ्रम, और धुंधली दृष्टि शामिल हैं। गंभीर दुष्प्रभावों में उच्च रक्तचाप, अनियमित दिल की धड़कन, और सांस लेने में कठिनाई हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल में प्रशिक्षित डॉक्टर द्वारा दी जानी चाहिए। इस दवा को लेने के बाद 24 घंटे तक वाहन न चलाएं और मशीनरी न चलाएं। शराब का सेवन न करें। अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं।
💊 ketamax 50mg injection Uses & Benefits
[{"condition":"Induction and maintenance of general anaesthesia","description":"This medicine is used to put patients to sleep and keep them asleep during surgery, especially when blood pressure stability is important.","evidence":"Well-established"},{"condition":"Emergency pain relief and sedation","description":"It provides rapid pain relief and sedation in emergency situations such as trauma, burns, or fractures.","evidence":"Well-established"},{"condition":"Procedural sedation","description":"Used for sedation during short painful procedures like dressing changes, minor surgery, or dental work in some settings.","evidence":"Well-established"},{"condition":"Treatment-resistant depression","description":"Given in controlled settings for severe depression that has not responded to other treatments.","evidence":"Emerging"},{"condition":"Acute asthma exacerbation","description":"Sometimes used in severe asthma attacks when other treatments are not working, due to its bronchodilator effects.","evidence":"Limited"}]
Off-label uses: [{"condition":"Complex regional pain syndrome","description":"Used in some pain clinics for severe chronic pain conditions.","evidence":"Limited"},{"condition":"Status epilepticus","description":"Occasionally used when other anticonvulsants fail.","evidence":"Limited"}]
Primary treatment for: Anaesthesia
Also treats: Acute pain, Treatment-resistant depression
📋 Drug Information
| Generic Name(s) | Ketamine (50mg) |
| Brand Name | ketamax 50mg injection |
| Manufacturer | Troikaa Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | General anaesthetic agents |
| Route of Administration | Parenteral (intravenous or intramuscular injection) |
| Storage | Store at room temperature (15-30°C). Protect from light. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works mainly by blocking the N-methyl-D-aspartate (NMDA) receptor in the brain, which is involved in pain perception and memory. It also interacts with opioid receptors, monoamine receptors, and voltage-gated calcium channels. This leads to a dissociative state where the patient feels detached from their body and surroundings, while still maintaining protective reflexes and breathing. It also stimulates the sympathetic nervous system, causing increased heart rate and blood pressure.
Mechanism Steps
💡 How to Take ketamax 50mg injection
Strength: 50mg injection
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the indication, patient's age, weight, and medical condition. For induction of anaesthesia, a typical intravenous dose is 1-2 mg/kg, and for maintenance, 0.5-1 mg/kg as needed. For pain relief, lower doses may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower doses due to increased sensitivity. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established from available information. Use with caution and monitor. |
| Hepatic Impairment | No specific dose adjustment is established from available information. Use with caution and monitor. |
| Maximum Daily Dose | Not established from the available information. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketamax 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Benzodiazepines | Major | |
| Opioids | Major | |
| Adrenaline | Major | |
| Thyroid hormones | Major | |
| Antihypertensives | Moderate | |
| Theophylline | Moderate | |
| Muscle relaxants | Minor |
🚨 Major Interactions
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Sympathomimetics (e.g., adrenaline, ephedrine)
- Thyroid hormones
⚡ Moderate Interactions
- Antihypertensives
- Theophylline
🍷 Alcohol Interaction
Alcohol increases the sedative and psychological effects of this medicine. Avoid alcohol for at least 24 hours after receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to ketamine","Uncontrolled high blood pressure","Severe heart disease","History of psychosis","Increased pressure inside the eye (glaucoma)","Increased pressure inside the brain","Thyroid disease"]
⚠️ Warnings & Precautions
["This medicine should be used only by trained healthcare professionals.","It can cause hallucinations and psychological reactions.","It may increase blood pressure and heart rate.","Use with caution in patients with head injury or eye injury.","Avoid use in patients with a history of drug abuse.","Do not drive or operate machinery for 24 hours after use."]
🤱 Lactation Safety
This medicine passes into breast milk. Breastfeeding should be avoided for at least 24 hours after receiving this medicine. Consult your doctor for specific advice.
💊 Overdose Management
Overdose can cause severe breathing depression, high blood pressure, and irregular heartbeat. Treatment is supportive and symptomatic. There is no specific antidote. Seek immediate medical attention.
⏰ Missed Dose
This medicine is given by a healthcare professional in a controlled setting, so missed doses are not applicable. If you miss a scheduled dose, contact your doctor immediately.
Additional Safety Advice
This medicine must be given only by a trained anaesthesiologist or doctor in a properly equipped medical facility. Patients should inform their doctor about all medical conditions, especially heart problems, high blood pressure, mental health disorders, thyroid issues, or liver disease. It is important to tell the doctor about all other medicines being taken, including sedatives, painkillers, and blood pressure medicines. After receiving this medicine, patients should not drive, operate machinery, or make important decisions for at least 24 hours. Alcohol and other central nervous system depressants should be avoided for at least 24 hours after receiving this medicine. Patients should not eat or drink for a specified time before the procedure as instructed by the doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Lower doses may be required, and close monitoring is essential.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
After surgery, this medicine may cause confusion or hallucinations. Ensure you have someone to accompany you home and avoid driving for 24 hours.
🦷 Dental Procedures
This medicine may be used for sedation during dental procedures in some settings. Inform your dentist if you have received this medicine recently.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities requiring full alertness for at least 24 hours after receiving this medicine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, confusion, and hallucinations. Do not drive, operate machinery, or make important decisions for at least 24 hours after receiving it.
🛑 When to Stop This Medicine
This medicine is given as a single dose or short course in a controlled setting. Do not stop or adjust the dose without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended outside of controlled clinical settings. Prolonged use can lead to tolerance, dependence, and psychological effects. Regular monitoring by a doctor is essential if used for chronic conditions.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the procedure and patient condition, other anaesthetics may be used.
Evidence: Well-establishedTechniques like nerve blocks or physical therapy may complement or replace this medicine in some cases.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is given in a hospital setting and is not for self-administration. If you are traveling after receiving this medicine, ensure you have a companion and do not drive for at least 24 hours. Carry a copy of your prescription and medical records if you need to travel soon after. Store the injection as directed by your healthcare provider.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 seconds after intravenous injection and within 3-5 minutes after intramuscular injection.
A: The effects usually last for 10-25 minutes after a single dose, but full recovery may take 1-2 hours.
A: No, this medicine must only be given by trained healthcare professionals in a hospital or clinic setting.
🤔 Common Patient Concerns
🔄 Substitutes for ketamax 50mg injection
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Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is only used as a recreational drug.
Fact: This medicine is a legitimate medical drug used for anaesthesia and pain relief in hospitals. - Myth: This medicine is safe to use at home.
Fact: This medicine must only be given by trained healthcare professionals in a medical facility.