ketamax 10mg injection - Ketamine (10mg) medicine

Ketmin 10mg Injection: Complete Medicine Guide

No reviews yet
🏭 Troikaa Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for anesthesia; emerging for depression and pain syndromes.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or palpitations
  • Difficulty breathing or shortness of breath
  • Severe headache with confusion
  • Hallucinations or severe agitation during recovery
  • Blood in urine or painful urination
  • Yellowing of skin or eyes
  • Swelling of face, lips, or throat

If experiencing severe symptoms, call emergency services immediately.

What is ketamax 10mg injection used for?

This medicine is a dissociative anesthetic used for general anesthesia, emergency surgery, and short procedures. It works by blocking NMDA receptors in the brain, providing pain relief, sedation, and amnesia while maintaining blood pressure. It must only be given by trained professionals in a hospital setting.

  • Generic Name: Ketamine (10mg)
  • Manufacturer: Troikaa Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ketamax 10mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा कीटामाइन हाइड्रोक्लोराइड इंजेक्शन है, जिसका उपयोग अस्पतालों में एनेस्थीसिया (बेहोशी) के लिए किया जाता है। यह मुख्य रूप से सर्जरी, आपातकालीन ऑपरेशन, और छोटी प्रक्रियाओं के दौरान दर्द निवारण और बेहोशी के लिए दी जाती है। यह दवा दिमाग में NMDA रिसेप्टर्स को ब्लॉक करके काम करती है, जिससे दर्द का एहसास कम होता है और मरीज को याद नहीं रहता। यह दवा केवल प्रशिक्षित डॉक्टर या एनेस्थेसियोलॉजिस्ट द्वारा ही दी जानी चाहिए। इसे घर पर या खुद से नहीं लगाया जा सकता। उच्च रक्तचाप, हृदय रोग, या मानसिक बीमारी वाले मरीजों को यह दवा सावधानी से दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतिभ्रम, बुरे सपने, भ्रम, मतली, उल्टी, मुंह में लार बढ़ना, और रक्तचाप या हृदय गति बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में तेज रक्तचाप, अनियमित हृदय गति, सांस रुकना, और गले में ऐंठन हो सकती है। दुर्लभ मामलों में एलर्जी, लिवर एंजाइम बढ़ना, या मूत्राशय की समस्या हो सकती है। इनका प्रबंधन डॉक्टर द्वारा किया जाता है।

सुरक्षा सलाह: यह दवा केवल अस्पताल में प्रशिक्षित डॉक्टर द्वारा ही दी जानी चाहिए। इंजेक्शन लगने के 24 घंटे तक वाहन न चलाएं और मशीनरी न चलाएं। अपने डॉक्टर को हृदय रोग, उच्च रक्तचाप, थायरॉइड, या मानसिक बीमारी की जानकारी दें। शराब और अन्य नींद की दवाओं से बचें। गर्भवती महिलाओं को यह दवा केवल जरूरत पड़ने पर ही दी जानी चाहिए। स्तनपान कराने वाली महिलाएं 24 घंटे तक स्तनपान न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ketamax 10mg injection Uses & Benefits

[{"condition":"Induction and maintenance of general anesthesia","description":"Used for starting and maintaining anesthesia during surgery, especially in emergency or low-blood-pressure situations.","evidence":"Well-established"},{"condition":"Emergency surgery in hemodynamically unstable patients","description":"Preferred in trauma or shock because it supports blood pressure better than many other anesthetics.","evidence":"Well-established"},{"condition":"Short diagnostic and therapeutic procedures","description":"Provides sedation and pain relief for procedures like dressing changes, fracture reduction, and minor surgeries.","evidence":"Well-established"},{"condition":"Treatment-resistant depression","description":"Used off-label as a rapid-acting antidepressant in specialist settings.","evidence":"Emerging"},{"condition":"Complex regional pain syndrome","description":"Low-dose infusions may help manage severe chronic pain unresponsive to other treatments.","evidence":"Limited"}]

Off-label uses: [{"condition":"Treatment-resistant depression","description":"Intravenous ketamine has shown rapid antidepressant effects in some patients with severe depression that has not responded to standard treatments.","evidence":"Moderate"},{"condition":"Acute suicidal ideation","description":"May rapidly reduce suicidal thoughts in emergency psychiatric settings.","evidence":"Limited"},{"condition":"Refractory status epilepticus","description":"Used as an add-on therapy for seizures that do not respond to standard anticonvulsants.","evidence":"Limited"},{"condition":"Complex regional pain syndrome","description":"Low-dose ketamine infusions can provide significant pain relief in some patients.","evidence":"Limited"}]

Primary treatment for: Anesthesia

Also treats: Treatment-resistant depression, Complex regional pain syndrome, Refractory status epilepticus

📋 Drug Information

Generic Name(s)Ketamine (10mg)
Brand Nameketamax 10mg injection
ManufacturerTroikaa Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassGeneral anaesthetic agents
Route of AdministrationParenteral (intravenous or intramuscular)
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine in a setting with full resuscitation equipment.
2
Monitor blood pressure and heart rate closely during and after administration.
3
Consider using a benzodiazepine to reduce emergence reactions.
4
Use lower doses in elderly patients and those with liver or kidney impairment.
5
Avoid concurrent use with sympathomimetics to prevent severe hypertension.
6
Ensure the patient is in a quiet, dimly lit environment during recovery.
7
Document any history of psychosis or cardiovascular disease before use.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Need for anesthesia during surgery
This medicine is commonly used for this.
Likely Use
Severe pain in emergency settings
This medicine provides rapid pain relief.
Likely Use
Treatment-resistant depression
Used off-label under specialist supervision.
Likely Use
Common cold
This medicine is not for infections.
Not Primary
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered intravenously or intramuscularly, so absorption is rapid and complete. After intramuscular injection, peak plasma levels are reached within 5 to 15 minutes. Intravenous administration produces immediate effects.
DistributionThis medicine is highly lipid-soluble and distributes rapidly to highly perfused tissues such as the brain, heart, and lungs. It then redistributes to less perfused tissues like muscle and fat. It crosses the placenta and is present in breast milk.
Protein BindingApproximately 10% to 30% bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4, CYP2B6, and CYP2C9, into active metabolite norketamine and other inactive metabolites.
Half-LifeThe elimination half-life is approximately 2 to 3 hours for ketamine and 4 to 6 hours for its active metabolite norketamine.
ExcretionMetabolites are excreted primarily in the urine (about 90%) and feces (about 10%). Less than 5% is excreted unchanged in urine.
BioavailabilityIntravenous: 100%; Intramuscular: approximately 93%.
Onset of ActionIntravenous: 30 seconds to 1 minute; Intramuscular: 3 to 5 minutes.
Peak Plasma TimeIntravenous: immediate; Intramuscular: 5 to 15 minutes.
Duration of ActionIntravenous: 5 to 10 minutes for anesthesia; Intramuscular: 12 to 25 minutes. Analgesic effects may last longer.

How It Works

This medicine works primarily as a non-competitive antagonist at the N-methyl-D-aspartate (NMDA) receptor, a type of glutamate receptor in the brain and spinal cord. By blocking these receptors, it reduces the release of excitatory neurotransmitters, leading to dissociation, amnesia, analgesia, and anesthesia. It also interacts with opioid receptors, monoamine transporters, and voltage-gated calcium channels, contributing to its pain-relieving and psychotropic effects. Unlike many anesthetics, it stimulates the sympathetic nervous system, which helps maintain blood pressure and heart rate.

Mechanism Steps

1
NMDA receptor blockade: This medicine binds to the phencyclidine site within the NMDA receptor channel, preventing glutamate from activating the receptor.
2
Reduced excitatory neurotransmission: Blocking NMDA receptors decreases the release of excitatory neurotransmitters like glutamate and substance P, reducing pain signaling.
3
Dissociation and anesthesia: The brain's cortex and limbic system become functionally disconnected, producing a trance-like state with analgesia and amnesia.
4
Sympathetic stimulation: This medicine increases sympathetic outflow, leading to elevated heart rate, blood pressure, and cardiac output.
5
Emergence and recovery: As the drug wears off, patients may experience vivid dreams, hallucinations, or confusion, which usually resolve within a few hours.

💡 How to Take ketamax 10mg injection

Strength: Injection: 10 mg/mL

1This medicine is administered by a healthcare professional only.
2It is given intravenously or intramuscularly in a hospital or clinic setting.
3You will be monitored for blood pressure, heart rate, and breathing.
4Do not attempt to take this medicine on your own.
5Follow all pre-procedure fasting instructions.
6Inform your doctor about all medicines you take and any allergies.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the indication, patient's age, weight, cardiovascular status, and renal and hepatic function. For anesthesia induction, a typical intravenous dose is 1-2 mg/kg, but lower doses are used for sedation or pain. Intramuscular doses are usually 4-10 mg/kg. It must only be administered by trained anesthesia providers in a hospital setting. Do not attempt to self-administer.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician or pediatric anesthesiologist.
Elderly DosageElderly patients may require lower doses due to increased sensitivity and reduced clearance. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is established, but use with caution in patients with renal impairment. Monitor closely.
Hepatic ImpairmentDose reduction may be necessary in patients with hepatic impairment due to reduced metabolism. Individualize by a qualified clinician.
Maximum Daily DoseNot established from the available information. Dosing is individualized by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Before procedure
Follow fasting instructions
To prevent aspiration during anesthesia.
After procedure
Start with clear liquids
To avoid nausea and vomiting.
Alcohol
Avoid
Increases sedation and respiratory depression.
Grapefruit juice
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 This medicine is given by a healthcare professional in a controlled setting.
→ Missed doses are not applicable for self-administration.
💡 If you miss a scheduled dose in a clinical setting, inform your healthcare provider immediately.

⚠️ Side Effects of ketamax 10mg injection

✅ Common Side Effects

Hallucinations and vivid dreams (Common (10-30%))
Usually resolve within a few hours. A quiet, dimly lit recovery area can help reduce distress.
Nausea and vomiting (Common (5-15%))
Inform nursing staff. Anti-nausea medicines can be given if needed.
Increased salivation (Common (5-10%))
May require suctioning during anesthesia. Usually not dangerous.
Elevated blood pressure and heart rate (Common (10-20%))
Monitored by anesthetist. Usually transient and managed if necessary.
Confusion or disorientation (Common (5-15%))
Reassurance and a calm environment help. Usually resolves within hours.

🚨 Serious Side Effects

Severe hypertension (Uncommon (1-2%))
Requires immediate medical management. Blood pressure is monitored during use.
Respiratory depression (Rare (<1%))
May require assisted ventilation. Close monitoring is essential.
Laryngospasm (Rare (<1%))
Requires immediate airway management by a trained provider.
Emergence delirium (Uncommon (5-10%))
May require sedation with benzodiazepines. Reassurance and quiet environment help.
Anaphylaxis (Very rare (<0.1%))
Emergency treatment with epinephrine and supportive care.

⚠️ Rare Side Effects

Liver enzyme elevation
Monitor liver function if prolonged use. Usually reversible.
Cystitis (bladder inflammation)
Report painful urination or blood in urine. May require discontinuation.
Cognitive impairment
Neuropsychological assessment if symptoms persist.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ephedrine Major
Midazolam Major
Morphine Major
Ketoconazole Moderate
Rifampicin Moderate
Amlodipine Moderate
Theophylline Minor
Halothane Minor
Alcohol Major
Grapefruit juice Moderate

🚨 Major Interactions

  • Sympathomimetics (e.g., ephedrine, amphetamines)
  • CNS depressants (e.g., benzodiazepines, opioids, alcohol)
  • Thyroid hormones

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)
  • Antihypertensives

🍷 Alcohol Interaction

Alcohol should be strictly avoided before and after receiving this medicine. Combining them increases the risk of severe sedation, respiratory depression, and dangerous drops in blood pressure. It can also worsen emergence reactions such as hallucinations and confusion.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ketamine","Uncontrolled hypertension","Severe coronary artery disease","History of psychosis","Increased intracranial pressure (relative)","Thyrotoxicosis"]

⚠️ Warnings & Precautions

["This medicine must only be administered by trained anesthesia providers.","Use with caution in patients with cardiovascular disease.","May cause emergence reactions; use benzodiazepines if needed.","Avoid in patients with a history of psychosis unless benefits outweigh risks.","Not for self-administration.","Do not drive or operate machinery for 24 hours after use.","Use with caution in the elderly and in patients with liver or kidney impairment."]

🤱 Lactation Safety

This medicine passes into breast milk. Breastfeeding should be avoided for at least 24 hours after a single dose. Consult your doctor for guidance.

💊 Overdose Management

Overdose can cause severe respiratory depression, apnea, and cardiovascular collapse. Treatment is supportive and symptomatic. Maintain airway, breathing, and circulation. There is no specific antidote. Contact emergency services immediately.

⏰ Missed Dose

This medicine is given by a healthcare professional in a controlled setting. Missed doses are not applicable for self-administration. If you miss a scheduled dose in a clinical setting, inform your healthcare provider immediately.

Additional Safety Advice

General Safety

This medicine must only be given by a qualified anesthesia provider in a hospital or clinic with resuscitation equipment. Do not drive or operate machinery for at least 24 hours after receiving it. Inform your doctor if you have heart disease, high blood pressure, thyroid problems, or a history of mental health conditions. Avoid alcohol and other sedatives before and after administration. Tell your doctor about all medicines you take, especially stimulants, antidepressants, and blood pressure drugs. Do not use this medicine if you are pregnant unless clearly needed. Breastfeeding should be avoided for 24 hours after a dose. Keep all follow-up appointments.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine and may require lower doses. They are also at higher risk of cardiovascular side effects and emergence reactions. Close monitoring is essential.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss with your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed. Effective contraception is advised during treatment.

🏥 Post-Surgery Considerations

After surgery, you will be monitored in a recovery area. You may experience confusion, hallucinations, or nausea. These usually resolve within a few hours. Follow your surgeon's instructions for post-operative care.

🦷 Dental Procedures

This medicine may be used for sedation during dental procedures in hospital settings. Inform your dentist if you have received this medicine recently, as it can interact with other sedatives.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest after receiving this medicine.
🥗
Avoid alcohol and recreational drugs.
😴
Stay hydrated to help flush the medicine from your system.
💧
Follow your doctor's advice for follow-up care.
🧘
Do not drive or operate machinery for at least 24 hours.
🌞
Eat a light, healthy diet as tolerated after the procedure.

🏋️ Exercise Considerations

Avoid strenuous exercise for at least 24 hours after receiving this medicine, as it can cause dizziness and increase the risk of falls. Gradually resume normal activities as you feel able.

🥗 Diet Recommendations

Start with clear liquids after the procedure.
Eat light, bland foods if you feel nauseous.
Avoid alcohol for at least 24 hours.
Stay well hydrated.
Avoid grapefruit juice.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, confusion, and hallucinations. You should not drive, operate machinery, or make important decisions for at least 24 hours after receiving it. Arrange for someone to take you home and stay with you.

🛑 When to Stop This Medicine

This medicine is given as a single dose or short course in a controlled setting. Do not stop any prescribed treatment without consulting your doctor. If you experience severe side effects, inform your healthcare provider immediately.

📅 Long-Term Use Effects

Long-term use of this medicine, especially at high doses or recreationally, can lead to cognitive impairment, memory problems, and bladder damage (ketamine cystitis). It may also cause dependence. Medical use is typically short-term and monitored. Regular follow-up and monitoring of liver and kidney function are advised for prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Propofol

Another anesthetic agent with rapid onset and offset.

Evidence: Well-established
Etomidate

Anesthetic with minimal cardiovascular effects.

Evidence: Well-established
Regional anesthesia

Nerve blocks or spinal anesthesia for specific procedures.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✅ DO

Keep out of reach of children

❌ DON'T

Do not use if solution is discolored or contains particles

✈️ Traveling with This Medicine

This medicine is administered in a hospital setting and is not for self-administration. If you are traveling after receiving this medicine, ensure you have a companion, avoid driving for 24 hours, and carry a copy of your prescription and medical records. Store any remaining vials in their original packaging at room temperature, protected from light. Check customs regulations if traveling internationally with this medicine.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a fractured leg requiring emergency surgery
He was in shock with low blood pressure. The anesthesiologist chose this medicine for induction because it supports blood pressure. He was asleep within a minute and woke up after surgery with no memory of the procedure. He experienced mild hallucinations during recovery, which resolved with reassurance.
💡 Lesson: This medicine is ideal for emergency surgery in unstable patients, but emergence reactions can occur and are usually manageable.
👤 A 50-year-old woman with severe depression not responding to standard antidepressants
She received a low-dose intravenous infusion of this medicine under specialist supervision. Within hours, her mood improved significantly, and she felt relief for several days. She continued with maintenance therapy.
💡 Lesson: This medicine can provide rapid relief in treatment-resistant depression, but it must be used under strict medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine works within 30 seconds when given intravenously and within 3-5 minutes when given intramuscularly.

Q: Will I be awake during the procedure?

A: You will be in a dissociative state, meaning you may appear awake but will not feel pain or remember the procedure.

Q: What are the common side effects?

A: Common side effects include hallucinations, vivid dreams, nausea, vomiting, and increased blood pressure.

Q: Can I eat before receiving this medicine?

A: You will be asked to fast for several hours before the procedure to prevent complications.

Q: Is this medicine safe for pregnant women?

A: It should be used only if clearly needed, as risks to the fetus are not fully established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long will I be asleep?
  • Will I remember anything during the procedure?
  • Is it safe for children?
  • Can I breastfeed after receiving this medicine?
  • What are the long-term effects of ketamine?
  • Can I drive after receiving this medicine?

🔄 Substitutes for ketamax 10mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Ketamine is only a recreational drug.
    Fact: Ketamine is a legitimate prescription medicine used for anesthesia and pain management in hospitals.
  • Myth: Ketamine is safe to use at home.
    Fact: Ketamine must only be administered by trained healthcare professionals in a controlled setting.
  • Myth: Ketamine causes permanent brain damage.
    Fact: When used appropriately in medical settings, ketamine is safe and does not cause permanent brain damage.

🔄 Alternative Options

Generic Alternatives

  • Ketamine injection

Brand Alternatives

  • Ketmin 10mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Ketamine","class":"Dissociative anesthetic","route":"Parenteral","main_use":"Anesthesia, pain, depression","onset":"30 seconds IV"},{"medicine":"Propofol","class":"Intravenous anesthetic","route":"Parenteral","main_use":"Anesthesia, sedation","onset":"30-60 seconds IV"},{"medicine":"Etomidate","class":"Intravenous anesthetic","route":"Parenteral","main_use":"Anesthesia induction","onset":"30-60 seconds IV"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory