Amendo 750mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Seizures that are more frequent or severe than usual
- Sudden mood changes, depression, or suicidal thoughts
- Rash, blisters, or peeling skin
- Swelling of face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe abdominal pain radiating to the back
- Unusual bleeding or bruising
- Yellowing of skin or eyes
- Severe dizziness or fainting
If experiencing severe symptoms, call emergency services immediately.
What is keppra 750mg tablet used for?
This medicine is a prescription anticonvulsant containing levetiracetam 750 mg. It is used to treat partial-onset, myoclonic, and primary generalized tonic-clonic seizures. It works by binding to SV2A protein in the brain to stabilize electrical activity. Take it exactly as prescribed, usually twice daily, and do not stop suddenly.
- Generic Name: Levetiracetam (750mg)
- Manufacturer: UCB India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 keppra 750mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवेटिरासेटम 750 मिलीग्राम की एक प्रिस्क्रिप्शन गोली है जिसका उपयोग मिर्गी के दौरे को नियंत्रित करने के लिए किया जाता है। यह आंशिक दौरे, मायोक्लोनिक दौरे और प्राइमरी जनरलाइज्ड टॉनिक-क्लोनिक दौरे के इलाज में प्रभावी है। यह मस्तिष्क में एक प्रोटीन से जुड़कर दौरे पैदा करने वाली असामान्य विद्युत गतिविधि को स्थिर करती है। इसे डॉक्टर के निर्देशानुसार दिन में दो बार लिया जाता है। इसे अचानक बंद नहीं करना चाहिए क्योंकि इससे दौरे बढ़ सकते हैं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, कमजोरी और अस्थिरता शामिल हैं। कुछ लोगों में चिड़चिड़ापन, आक्रामकता, चिंता या अवसाद भी हो सकता है। दुर्लभ मामलों में त्वचा पर गंभीर दाने, रक्त कोशिकाओं में कमी, अग्न्याशय की सूजन, मतिभ्रम या आत्महत्या के विचार हो सकते हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। इसे सूखी और ठंडी जगह पर रखें। बच्चों की पहुंच से दूर रखें।
💊 keppra 750mg tablet Uses & Benefits
[{"condition":"Partial-onset seizures","description":"Used as monotherapy or add-on therapy to reduce the frequency of partial seizures in adults and children.","evidence":"Well-established"},{"condition":"Myoclonic seizures in juvenile myoclonic epilepsy","description":"Helps control sudden brief muscle jerks in patients with this specific epilepsy syndrome.","evidence":"Well-established"},{"condition":"Primary generalized tonic-clonic seizures","description":"Effective in reducing the frequency of generalized seizures with loss of consciousness and convulsions.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Neuropathic pain","description":"Occasionally used for nerve pain, though not FDA-approved for this purpose.","evidence":"Limited"},{"condition":"Tardive dyskinesia","description":"May be tried off-label for involuntary movements caused by antipsychotic drugs.","evidence":"Limited"}]
Primary treatment for: Epilepsy
Also treats: Partial-onset seizures, Myoclonic seizures, Primary generalized tonic-clonic seizures
📋 Drug Information
| Generic Name(s) | Levetiracetam (750mg) |
| Brand Name | keppra 750mg tablet |
| Manufacturer | UCB India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Synaptic vescicle 2 A protein ligand (AED) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to a protein called synaptic vesicle protein 2A (SV2A) in the brain. This binding modulates the release of neurotransmitters, particularly glutamate and GABA, which helps stabilize electrical activity in the brain and prevents seizures from spreading. Unlike many other antiepileptic drugs, it does not act primarily on sodium channels or GABA receptors, which may explain its unique side effect profile and low interaction potential.
Mechanism Steps
💡 How to Take keppra 750mg tablet
Strength: 750 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose for adults is 500 mg twice daily, which may be increased by 500 mg twice daily every 2 to 4 weeks up to a maximum of 1500 mg twice daily, depending on the type of seizures and response. For partial-onset seizures, the effective dose is often 500 mg to 1500 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require a lower dose because of age-related decline in renal function. Dose should be adjusted based on creatinine clearance. Consult a doctor for individualized dosing. |
| Renal Impairment | Dose adjustment is required in patients with impaired renal function. For creatinine clearance 50-80 mL/min, the dose is 500-1000 mg every 12 hours; for 30-50 mL/min, 250-750 mg every 12 hours; for less than 30 mL/min, 250-500 mg every 12 hours; for end-stage renal disease on dialysis, 500-1000 mg every 24 hours with an additional dose after dialysis. Always consult a nephrologist or clinician for precise dosing. |
| Hepatic Impairment | No dose adjustment is needed for mild to moderate hepatic impairment. In severe hepatic impairment with concurrent renal impairment, dose reduction may be necessary. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 3000 mg per day, given as 1500 mg twice daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of keppra 750mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CNS depressants | Major | |
| Methotrexate | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Valproic acid | Moderate | |
| Oral contraceptives | Minor | |
| Warfarin | Minor |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Methotrexate
⚡ Moderate Interactions
- Carbamazepine
- Phenytoin
- Valproic acid
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase central nervous system depression, leading to excessive drowsiness, dizziness, and impaired coordination. Alcohol may also lower the seizure threshold, potentially reducing the effectiveness of this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levetiracetam or any component of the formulation","Severe renal impairment (dose adjustment required, not absolute contraindication)"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly; withdrawal may cause seizures.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Antiepileptic drugs increase the risk of suicidal thoughts or behavior; monitor mood closely.","Serious skin reactions (Stevens-Johnson syndrome) can occur; seek immediate care if rash develops.","Use with caution in patients with renal impairment; dose adjustment is necessary.","May cause dizziness and unsteadiness; avoid falls.","Alcohol should be avoided due to additive CNS depression."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, agitation, aggression, respiratory depression, and coma. There is no specific antidote. Treatment should be supportive and symptomatic, including monitoring of vital signs and airway management. Hemodialysis may be considered in severe cases, as levetiracetam is dialyzable.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as this can cause withdrawal seizures. Swallow the tablet whole with a glass of water; do not crush or chew it. You may take it with or without food, but taking it with food may reduce stomach upset. Avoid drinking alcohol while on this medicine because it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep all your medical appointments and lab tests. Store this medicine at room temperature away from moisture and heat. Keep it out of reach of children. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Never double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can lead to higher levels of this medicine in the body. Dose adjustment based on creatinine clearance is necessary. Elderly patients may also be more sensitive to side effects such as drowsiness, dizziness, and unsteadiness, increasing the risk of falls. Regular monitoring of kidney function and dose adjustment are recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before conception. This medicine is Pregnancy Category C, and the risks to the fetus are not fully known. Your doctor may consider switching to another antiepileptic drug or adjusting the dose. It is important to control seizures during pregnancy, as seizures can harm both the mother and the baby. Use effective contraception while taking this medicine unless you are planning a pregnancy.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and other medications used during surgery. Your doctor may need to adjust the dose or monitor you more closely. Continue taking this medicine as prescribed unless your doctor advises otherwise.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain local anesthetics or sedatives. Your dentist may need to adjust the type or dose of anesthesia. Maintain good oral hygiene to prevent dental problems, as some antiepileptic drugs can cause gum overgrowth, though this is less common with levetiracetam.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine, but you should avoid activities that could be dangerous if you experience drowsiness or a seizure, such as swimming alone, cycling on busy roads, or operating heavy machinery. Always warm up and cool down, and stay hydrated. If you feel dizzy or unsteady, stop and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. You should avoid these activities until you know how the medicine affects you. It may also cause mood changes that can impact your work and relationships. Discuss any concerns with your doctor. With proper dose adjustment, most people can continue their normal daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe rash, suicidal thoughts, or signs of an allergic reaction, seek immediate medical attention. Your doctor may decide to stop the medicine or switch you to another medication. Always taper the dose gradually under medical supervision to avoid withdrawal seizures.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated. Some patients may experience persistent drowsiness, mood changes, or behavioral effects. Regular monitoring of kidney function is important, especially in elderly patients. There is no evidence of tolerance or addiction. However, long-term use may be associated with a slight increase in the risk of suicidal thoughts, so mood should be monitored. Periodic blood tests may be needed to check kidney function and blood counts.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A high-fat, low-carbohydrate diet that can help reduce seizures in some patients, especially children.
Evidence: Well-established for certain types of epilepsyA device implanted under the skin that sends electrical signals to the vagus nerve to reduce seizures.
Evidence: Well-established for refractory epilepsySurgical removal of the brain area causing seizures, considered for some patients with drug-resistant epilepsy.
Evidence: Well-established for selected patients💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you have a seizure disorder, you should inform your healthcare provider before receiving any vaccine, as fever from vaccination can sometimes trigger seizures. Follow your doctor's advice regarding vaccination schedules.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Carry enough supply for the entire trip plus extra in case of delays. Check local customs regulations for controlled substances, though levetiracetam is generally not restricted.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but it may take several weeks to achieve full seizure control. Your doctor will adjust the dose based on your response.
A: No, you should never stop this medicine suddenly. Doing so can cause withdrawal seizures. Always consult your doctor before making any changes.
A: This medicine is Pregnancy Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk. Consult your doctor if you are pregnant or planning to become pregnant.
A: It is best to avoid alcohol because it can increase drowsiness and dizziness, and may lower the seizure threshold.
🤔 Common Patient Concerns
🔄 Substitutes for keppra 750mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia levetiracetam 750mg tabletDavaindia Generic Pharmacy ₹100.00 51.6% CHEAPER
-
zolve 750mg tabletZoic Lifesciences ₹140.00 32.2% CHEAPER
-
lavesal 750mg tabletSalas Pharmaceuticals ₹150.67 27.1% CHEAPER
-
levilep 750mg tablet xrIkon Pharmachem Pvt Ltd ₹154.69 25.1% CHEAPER
-
levtam 750mg tabletTorrent Pharmaceuticals Ltd ₹157.50 23.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a sleeping pill.
Fact: This medicine is an anticonvulsant used to treat epilepsy, not a sleeping aid. It may cause drowsiness as a side effect. - Myth: You can stop this medicine once seizures are controlled.
Fact: Stopping this medicine suddenly can cause withdrawal seizures. Always consult your doctor before making any changes. - Myth: This medicine is addictive.
Fact: This medicine is not addictive, but it can cause dependence in the sense that stopping it abruptly can lead to seizures.
🔄 Alternative Options
Generic Alternatives
- Levetiracetam 750 mg tablet
Brand Alternatives
- Keppra 750 mg tablet
- Levipil 750 mg tablet
- Torleva 750 mg tablet
- Epival 750 mg tablet