Keno 200mg Tablet (Trimethoprim 200mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in urine, stool, or vomit
- Severe abdominal pain or persistent vomiting
- Difficulty breathing or swelling of the face, lips, tongue, or throat
- Severe skin rash with blisters, peeling, or sores in the mouth or eyes
- Fever with sore throat, mouth ulcers, or unusual tiredness
- Easy bruising or bleeding that does not stop
- Markedly decreased urine output or swelling of the legs
- Yellowing of the skin or eyes, or dark urine
- Irregular heartbeat, palpitations, or severe muscle weakness
- Severe headache with stiff neck or sensitivity to light
If experiencing severe symptoms, call emergency services immediately.
What is keno 200mg tablet used for?
This medicine contains Trimethoprim 200 mg, an antibiotic used to treat certain bacterial infections, especially uncomplicated urinary tract infections. It works by blocking an enzyme bacteria need to make folate, which stops their growth. It is taken by mouth, usually twice daily, and the dose must be individualized by a doctor. It is not recommended during pregnancy, and it can interact with several other medicines.
- Generic Name: Trimethoprim (200mg)
- Manufacturer: Mancare Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 keno 200mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ट्राइमेथोप्रिम 200 मिलीग्राम की गोली है, जिसका उपयोग कुछ जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से मूत्र मार्ग के साधारण संक्रमण (यूटीआई) के लिए दी जाती है, जिसमें पेशाब करते समय जलन, बार-बार पेशाब आना और पेट के निचले हिस्से में दर्द जैसे लक्षण होते हैं। यह कुछ श्वसन संक्रमण, त्वचा संक्रमण और दस्त के मामलों में भी दी जा सकती है, लेकिन केवल तब जब डॉक्टर को पता हो कि संक्रमण इस दवा के प्रति संवेदनशील है। यह दवा वायरस से होने वाले संक्रमण जैसे सर्दी-जुकाम या फ्लू पर असर नहीं करती। यह गर्भवती महिलाओं के लिए अनुशंसित नहीं है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें और कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, दस्त, पेट में असहजता, भूख कम लगना, सिरदर्द और त्वचा पर चकत्ते शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। कभी-कभी गंभीर दुष्प्रभाव भी हो सकते हैं, जैसे त्वचा पर गंभीर प्रतिक्रिया, खून की कोशिकाओं में कमी, खून में पोटैशियम का स्तर बढ़ना, गुर्दे की कार्यक्षमता में गिरावट, या गंभीर एलर्जी। अगर आपको लगातार गले में दर्द, मुंह में छाले, बुखार, आसानी से चोट लगना या खून आना, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर फफोले दिखें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को पूरे गिलास पानी के साथ निगलें। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। अगर डॉक्टर न कहें तो गोली को चबाएं या तोड़ें नहीं। एंटीबायोटिक का पूरा कोर्स करें, भले ही आपको कुछ दिनों में आराम लगने लगे। बीच में दवा बंद करने से संक्रमण फिर से हो सकता है। इलाज के दौरान शराब न पिएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर खून पतला करने वाली दवाएं, पानी की गोलियां, ब्लड प्रेशर और मधुमेह की दवाएं। पोटैशियम सप्लीमेंट या नमक के विकल्प बिना पूछे न लें। गुर्दे या लिवर की बीमारी हो तो डॉक्टर को जरूर बताएं। दवा को ठंडी और सूखी जगह पर, धूप से दूर, बच्चों की पहुंच से बाहर रखें।
💊 keno 200mg tablet Uses & Benefits
[{"condition":"Uncomplicated urinary tract infection","description":"This medicine is used to treat simple bladder infections caused by susceptible bacteria, helping to clear symptoms such as burning during urination and frequent urination.","evidence":"Well-established"},{"condition":"Recurrent urinary tract infection prevention","description":"In selected patients, a doctor may prescribe this medicine for long-term low-dose prevention of repeated urinary tract infections.","evidence":"Established in selected patients"},{"condition":"Acute exacerbation of chronic bronchitis","description":"This medicine may be used when a doctor identifies a susceptible bacterium as the cause of a flare-up of chronic bronchitis.","evidence":"Established for susceptible organisms"},{"condition":"Pneumocystis jirovecii pneumonia","description":"This medicine is used in combination with other medicines for the treatment and prevention of this serious lung infection in specific patient groups.","evidence":"Established in combination regimens"},{"condition":"Traveler's diarrhea","description":"This medicine may be prescribed for some cases of infectious diarrhea when a susceptible organism is suspected or confirmed.","evidence":"Limited to specific situations"},{"condition":"Skin and soft tissue infections","description":"This medicine may be used for certain skin infections caused by susceptible bacteria, often guided by culture results.","evidence":"Limited to susceptible organisms"}]
Off-label uses: [{"condition":"Prostatitis","description":"This medicine is sometimes used for certain types of prostate infection, but this is not a standard approved use and should only be considered by a specialist.","evidence":"Limited"},{"condition":"Nocardiosis","description":"This medicine has been used in combination therapy for this rare infection in some patients, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Uncomplicated urinary tract infection
Also treats: Recurrent urinary tract infection, Acute exacerbation of chronic bronchitis, Pneumocystis jirovecii pneumonia, Traveler's diarrhea, Skin and soft tissue infections
📋 Drug Information
| Generic Name(s) | Trimethoprim (200mg) |
| Brand Name | keno 200mg tablet |
| Manufacturer | Mancare Labs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Sulphonamides |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in a dry place away from direct sunlight and moisture. Keep it in its original container with the lid tightly closed. Do not store it in the bathroom. Keep it out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the manufacturer's packaging. Always check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information for this specific product. Treatment guidelines for urinary tract infections generally recommend using antibiotics based on local resistance patterns and patient factors. Always follow your doctor's advice. |
| ICMR Guideline | Not established from the available information for this specific product. Indian guidelines for urinary tract infections recommend culture-guided therapy where possible and caution against unnecessary antibiotic use. Consult your doctor for guidance. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the bacterial enzyme dihydrofolate reductase. This enzyme converts dihydrofolic acid into tetrahydrofolic acid, which is required for the production of thymidine, purines, and certain amino acids that bacteria need to build DNA and proteins. By blocking this step, the medicine stops susceptible bacteria from multiplying and allows the body's immune system to clear the infection. Because human cells can take up preformed folate from the diet, they are less dependent on this pathway, which helps explain the selective antibacterial action of this medicine.
Mechanism Steps
💡 How to Take keno 200mg tablet
Strength: This medicine is available as an immediate-release tablet containing 200 mg of Trimethoprim, for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for uncomplicated urinary tract infection is 200 mg twice daily for 3 to 7 days, but the exact dose and duration depend on the infection being treated, your kidney function, and other medicines you take. For prevention of recurrent urinary tract infections, a lower dose such as 100 mg once daily at night may be used. For Pneumocystis jirovecii pneumonia, this medicine is used in combination with other medicines at higher doses under specialist supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific 200 mg tablet. Children usually require weight-based dosing using other formulations. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Older adults may need a lower dose because kidney function often declines with age. Your doctor may check your kidney function before and during treatment and adjust the dose accordingly. Older adults are also more likely to take other medicines that can interact with this medicine, so a careful review of all medicines is important. |
| Renal Impairment | This medicine is removed mainly by the kidneys, so the dose may need to be reduced in people with kidney impairment. For mild to moderate kidney impairment, the doctor may reduce the dose or extend the dosing interval. In severe kidney impairment, this medicine is usually avoided unless the doctor decides the benefit outweighs the risk. Regular monitoring of kidney function is recommended. |
| Hepatic Impairment | This medicine is partly metabolized in the liver. In people with severe liver impairment, the dose may need to be reduced or the medicine avoided. Your doctor will decide based on your liver function tests and overall condition. |
| Maximum Daily Dose | The maximum daily dose of this medicine depends on the indication and your kidney function. For most common infections, the maximum is 400 mg per day in divided doses. Higher doses may be used in specialist settings for specific infections, but only under close medical supervision. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of keno 200mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | |
| Warfarin | Major | |
| Spironolactone | Major | |
| ACE inhibitors | Major | |
| Phenytoin | Major | |
| Rifampicin | Moderate | |
| Dapsone | Moderate | |
| Clozapine | Moderate | |
| Digoxin | Moderate | |
| Amantadine | Moderate |
🚨 Major Interactions
- Methotrexate
- Potassium-sparing diuretics (for example, spironolactone, amiloride, triamterene)
- ACE inhibitors and angiotensin receptor blockers
- Phenytoin
- Warfarin
⚡ Moderate Interactions
- Rifampicin
- Dapsone
- Clozapine
- Digoxin
- Amantadine
🍷 Alcohol Interaction
It is best to avoid alcohol while taking this medicine. Alcohol can increase the chance of stomach upset, nausea, and liver-related side effects. It may also make it harder to judge how well the medicine is working. If you drink alcohol regularly, discuss this with your doctor before starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Trimethoprim or any other ingredient in this medicine","Pregnancy","Breastfeeding an infant with glucose-6-phosphate dehydrogenase deficiency or other metabolic conditions","Severe kidney impairment where dose adjustment is not possible","Severe liver impairment","Severe blood disorders such as severe anemia, low white cell count, or low platelet count","Use in combination with methotrexate unless supervised by a specialist","Known folate deficiency without appropriate supplementation"]
⚠️ Warnings & Precautions
["Tell your doctor if you have kidney or liver problems, as the dose may need adjustment.","Tell your doctor if you have a blood disorder or low folate levels.","This medicine can cause blood disorders. Report fever, sore throat, mouth ulcers, easy bruising, or bleeding.","This medicine can raise potassium levels. Avoid potassium supplements and salt substitutes unless your doctor approves.","This medicine can cause serious skin reactions. Stop the medicine and seek urgent care if you develop a painful rash or blisters.","This medicine may not be suitable during pregnancy. Use effective contraception and inform your doctor if you plan to become pregnant.","This medicine can interact with many other medicines. Always give your doctor a complete list of medicines you take.","Do not use this medicine to treat viral infections such as colds or flu.","Complete the full course as prescribed, even if you feel better, to prevent resistance.","Keep all follow-up appointments and blood tests."]
🤱 Lactation Safety
This medicine passes into breast milk. It is generally considered acceptable for most breastfeeding women when prescribed by a doctor, but it should be used with caution in women breastfeeding infants who have certain metabolic conditions such as glucose-6-phosphate dehydrogenase deficiency, or who are premature or jaundiced. Always consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
If you take too much of this medicine, seek medical help immediately. Overdose can cause nausea, vomiting, dizziness, headache, confusion, and blood disorders. Treatment is supportive and may include monitoring of blood counts, kidney function, and potassium levels. In severe cases, a doctor may consider giving folinic acid, which can help counteract the effects of the medicine on folate metabolism. Do not try to treat an overdose at home.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a full glass of water. You may take it with or without food, but taking it with food can reduce stomach upset. Do not crush, chew, or break the tablet unless your doctor or pharmacist has told you it is safe to do so. Complete the full course even if you start feeling better after a few days, because stopping early can allow the infection to return and can encourage bacterial resistance. Drink plenty of fluids while taking this medicine unless your doctor has told you to limit fluids. Avoid alcohol during treatment because it can worsen stomach upset and may affect how you feel. Tell your doctor about all other medicines you take, especially blood thinners, water tablets, blood pressure medicines, diabetes medicines, and other antibiotics. Do not take potassium supplements or salt substitutes containing potassium without asking your doctor. If you have kidney or liver problems, your doctor may adjust your dose or monitor you more closely. Keep all follow-up appointments and blood tests. Store this medicine at room temperature away from moisture and direct sunlight, and keep it out of reach of children. Do not use it after the expiry date printed on the pack.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function, which can increase the levels of this medicine in the body and raise the risk of side effects. Your doctor may check your kidney function before and during treatment and adjust the dose. Older adults are also more likely to take other medicines that can interact with this medicine, such as blood pressure medicines and water tablets. Regular monitoring of kidney function, blood counts, and potassium levels is important.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy because it can interfere with folate metabolism, which is important for the developing baby. If you are planning to become pregnant, talk to your doctor before taking this medicine. Use effective contraception while taking this medicine and for a short period after, unless your doctor advises otherwise. If you become pregnant while taking this medicine, contact your doctor immediately.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, tell your surgeon and anesthesiologist that you are taking this medicine. It can interact with other medicines used during surgery and can affect kidney function and potassium levels. Your doctor may advise you to stop the medicine before surgery or may adjust your other medicines. Do not stop the medicine on your own without consulting your doctor.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. This medicine can interact with other medicines and can rarely cause blood disorders that may affect bleeding. Your dentist may need to take extra precautions if you are having a procedure that involves bleeding. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine is unlikely to affect your ability to exercise, but if you feel dizzy, weak, or unwell, avoid strenuous activity until you feel better. Drink plenty of fluids before, during, and after exercise to stay hydrated. If you have a urinary tract infection, gentle exercise such as walking may be fine, but listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness, tiredness, or stomach upset, avoid driving or operating heavy machinery until you feel better. Take the medicine at the same time each day to fit it into your routine. If your work involves shift changes, talk to your doctor about how to adjust the timing of your doses.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full course prescribed by your doctor, even if you feel better. Stopping early can allow the infection to return and can make bacteria harder to treat. If you experience a serious side effect such as a severe skin rash, difficulty breathing, or unusual bleeding, stop the medicine and seek medical help immediately. Always consult your doctor before stopping this medicine for any other reason.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of blood disorders, folate deficiency, and bacterial resistance. It may also affect kidney function and potassium levels, especially in older adults or those with existing kidney disease. If you need to take this medicine for a long time, your doctor will monitor your blood counts, kidney function, and potassium levels regularly. Do not use this medicine for longer than prescribed without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water can help flush the urinary tract and reduce symptoms of mild urinary tract infections.
Evidence: Supportive careSome people use cranberry juice or supplements to help prevent urinary tract infections, but evidence for treatment is limited.
Evidence: LimitedProbiotics may help maintain gut and urinary tract health, but they are not a substitute for antibiotics when an infection is present.
Evidence: LimitedSimple pain relievers such as paracetamol may help with discomfort, but they do not treat the infection.
Evidence: Supportive care💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are due for a live vaccine, tell your doctor that you are taking an antibiotic. There is no need to delay routine vaccinations unless your doctor advises otherwise. If you are being treated for an infection, it is best to recover before getting any vaccine that could cause fever, so that symptoms are not confused.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified on the pack
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not leave the medicine where children can see or reach it
✅ DO
Check the expiry date before use
❌ DON'T
Do not use the medicine after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription or a letter from your doctor, especially if you are crossing international borders, as some countries have strict rules about antibiotics. Store the medicine in a cool, dry place away from direct sunlight and moisture. If you are crossing time zones, continue taking your doses at the same intervals as prescribed; you may need to adjust the timing gradually. Do not leave the medicine in a hot car or in checked luggage. If you are traveling to a region with high rates of antibiotic resistance, discuss with your doctor whether any additional precautions are needed. Always carry enough medicine for your entire trip plus a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but you may not notice improvement in symptoms for 24 to 48 hours. If your symptoms do not improve within 48 to 72 hours or get worse, contact your doctor.
A: Yes, you can take this medicine with or without food. Taking it with a meal may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine is not recommended during pregnancy because it can interfere with folate metabolism, which is important for the developing baby. Tell your doctor if you are pregnant or planning to become pregnant.
A: It is best to avoid alcohol while taking this medicine. Alcohol can worsen stomach upset and may increase the risk of liver-related side effects.
A: Yes, this medicine can interact with several other medicines, including blood thinners, water tablets, blood pressure medicines, methotrexate, and phenytoin. Always tell your doctor about all medicines you take.
A: This medicine is removed mainly by the kidneys and can occasionally affect kidney function, especially in people who already have kidney problems. Your doctor may check your kidney function before and during treatment.
A: Store it at room temperature between 15°C and 30°C in a dry place away from direct sunlight and moisture. Keep it in the original container and out of reach of children.
🤔 Common Patient Concerns
🔄 Substitutes for keno 200mg tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: This medicine only works against certain susceptible bacteria. It does not treat viral infections such as colds or flu. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You should complete the full course as prescribed to prevent the infection from returning and to reduce the risk of bacterial resistance. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is not recommended during pregnancy because it can interfere with folate metabolism, which is important for the developing baby. - Myth: This medicine can be shared with family members who have similar symptoms.
Fact: Never share antibiotics. The medicine may not be right for another person and can cause harm or resistance. - Myth: Taking extra doses will make the infection clear faster.
Fact: Taking more than the prescribed dose can increase the risk of side effects and does not improve cure rates. Always follow your doctor's instructions.
🔄 Alternative Options
Generic Alternatives
- Trimethoprim 200 mg tablet
- Trimethoprim 100 mg tablet
Brand Alternatives
- Keno 200mg Tablet