axepine 50mg tablet (Amoxapine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- New or worsening thoughts of self-harm or suicide.
- Irregular, fast, or pounding heartbeat.
- Fainting or severe dizziness.
- Seizure or convulsion.
- High fever with muscle stiffness, sweating, and confusion.
- Severe abdominal pain with vomiting or inability to pass stool.
- Yellowing of the eyes or skin, dark urine, or severe tiredness.
- Unusual bruising or bleeding.
- Sudden swelling of the face, lips, or throat.
- Confusion, hallucinations, or extreme agitation.
If experiencing severe symptoms, call emergency services immediately.
What is kamipox 50mg tablet used for?
This medicine is an oral tricyclic antidepressant containing amoxapine 50 mg. It is used mainly to treat major depressive disorder. It works by increasing serotonin and norepinephrine in the brain. It can cause drowsiness, dry mouth, and dizziness. It must be taken exactly as prescribed and should not be stopped suddenly.
- Generic Name: Amoxapine (50mg)
- Manufacturer: KC Laboratories
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kamipox 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा अमोक्सापिन 50 मिलीग्राम की एक टैबलेट है, जिसे मुख्य रूप से गंभीर अवसाद (मेजर डिप्रेशन) के इलाज के लिए इस्तेमाल किया जाता है। यह ट्राइसाइक्लिक एंटीडिप्रेसेंट दवाओं के समूह में आती है और दिमाग में सेरोटोनिन और नॉरएपिनेफ्रिन जैसे रसायनों के संतुलन को सुधारने में मदद करती है। इस दवा का असर तुरंत नहीं होता, बल्कि पूरा फायदा दिखने में कई हफ्ते लग सकते हैं। यह दवा उन लोगों के लिए है जिन्हें डॉक्टर ने अवसाद का निदान किया है और जिन्हें इस दवा से फायदा हो सकता है। इसे डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए। कुछ लोगों के लिए यह दवा सुरक्षित नहीं हो सकती, जैसे कि दिल की गंभीर बीमारी, हाल ही में दिल का दौरा, गंभीर लिवर रोग, या दौरे की समस्या वाले लोगों के लिए। इसलिए इस दवा को लेने से पहले अपनी पूरी स्वास्थ्य जानकारी डॉक्टर को बताना बहुत जरूरी है।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं, जैसे नींद आना, मुंह सूखना, धुंधला दिखना, कब्ज, चक्कर आना और पेशाब करने में कठिनाई। ये आमतौर पर शुरुआत में होते हैं और धीरे-धीरे कम हो जाते हैं, लेकिन अगर ये परेशान करने लगें तो डॉक्टर को बताएं। कुछ गंभीर दुष्प्रभाव भी हो सकते हैं, जैसे दिल की धड़कन अनियमित होना, बेहोशी, दौरे पड़ना, भ्रम होना, या सेरोटोनिन सिंड्रोम जिसमें बेचैनी, बुखार, पसीना और मांसपेशियों में अकड़न हो सकती है। अगर आपको खुद को नुकसान पहुंचाने के ख्याल आएं, तो तुरंत डॉक्टर से संपर्क करें। किसी भी असामान्य लक्षण को नजरअंदाज न करें और तुरंत मदद लें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और अपनी मर्जी से डोज न बदलें। टैबलेट को पानी के साथ पूरा निगलें। अगर पेट में जलन हो, तो इसे हल्के भोजन के साथ लें। इस दवा से नींद और धुंधलापन हो सकता है, इसलिए जब तक आपको इसका असर समझ न आए, गाड़ी चलाने या मशीन चलाने से बचें। शराब बिल्कुल न लें, क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अपने डॉक्टर को अपनी सभी दवाओं और सप्लीमेंट्स के बारे में बताएं। इस दवा को अचानक बंद न करें, क्योंकि इससे परेशानी हो सकती है। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। नियमित जांच के लिए डॉक्टर के पास जाते रहें।
💊 kamipox 50mg tablet Uses & Benefits
[{"condition":"Major depressive disorder","description":"This medicine is used to treat the symptoms of major depression, including persistent low mood, loss of interest, sleep changes, and difficulty concentrating.","evidence":"Well-established"},{"condition":"Depression with anxiety or agitation","description":"Because of its calming properties, this medicine is sometimes chosen for depression that is accompanied by anxiety, restlessness, or agitation.","evidence":"Moderate"},{"condition":"Depression with psychotic features","description":"Amoxapine has some antipsychotic-like activity, so it has been used in depression that includes psychotic symptoms, though this is not its primary approved use.","evidence":"Limited"}]
Off-label uses: [{"condition":"Neuropathic pain","description":"Tricyclic antidepressants are sometimes used off-label for nerve pain, but amoxapine is not a first-choice agent for this purpose.","evidence":"Limited"},{"condition":"Panic disorder","description":"Some tricyclic antidepressants have been studied for panic disorder, but amoxapine is not established as a standard treatment.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Tricyclic antidepressants are occasionally used to prevent migraines, but amoxapine is not a commonly recommended option.","evidence":"Limited"}]
Primary treatment for: Major depressive disorder
Also treats: Depression with anxiety, Depression with agitation, Depression with psychotic features
📋 Drug Information
| Generic Name(s) | Amoxapine (50mg) |
| Brand Name | kamipox 50mg tablet |
| Manufacturer | KC Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Tricyclic antidepressants |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight, heat, and moisture. Keep the tablets in their original container with the lid tightly closed. Do not store in the bathroom. Keep out of the reach of children and pets. |
| Shelf Life | The shelf life is typically 24 to 36 months from the date of manufacture, but the exact expiry date is printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works mainly by blocking the reuptake of two chemical messengers in the brain, serotonin and norepinephrine, which increases their availability in the spaces between nerve cells. This helps to restore normal mood signalling over time. Amoxapine also blocks certain receptors, including histamine H1, muscarinic acetylcholine, and alpha-1 adrenergic receptors, which explains many of its side effects such as drowsiness, dry mouth, and dizziness. In addition, its main metabolite, 7-hydroxyamoxapine, has dopamine-blocking activity similar to some antipsychotic medicines, which may contribute to its effects and to some of its risks.
Mechanism Steps
💡 How to Take kamipox 50mg tablet
Strength: Immediate-release tablet containing 50 mg of amoxapine.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults is 50 mg two to three times daily, and the dose may be gradually increased by the doctor depending on response and tolerability. Some patients may need up to 300 mg daily in divided doses, but higher doses are generally reserved for those who do not respond to lower doses and who are closely monitored. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medicines being taken. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults are more sensitive to the side effects of this medicine, especially drowsiness, confusion, dizziness, falls, and heart rhythm changes. Treatment is usually started at a lower dose, such as 25 mg to 50 mg daily, and increased slowly under close medical supervision. Regular monitoring of heart rhythm, blood pressure, and mental status is recommended. |
| Renal Impairment | People with kidney disease may eliminate this medicine more slowly and may need a lower dose. The exact dose adjustment is not established from the available information. Consult a qualified clinician for individualized dosing. |
| Hepatic Impairment | People with liver disease may metabolize this medicine more slowly and may need a lower dose. The exact dose adjustment is not established from the available information. Consult a qualified clinician for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 300 mg, but doses above 150 mg per day should only be used under close medical supervision. The exact maximum dose must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kamipox 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| SSRIs/SNRIs | Major | |
| Class IA/III antiarrhythmics | Major | |
| Anticholinergics | Major | |
| CNS depressants | Major | |
| CYP2D6 inhibitors | Moderate | |
| CYP1A2 inhibitors | Moderate | |
| Antihypertensives | Moderate | |
| Thyroid medications | Moderate | |
| Cimetidine | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other serotonergic drugs (SSRIs, SNRIs, triptans, tramadol, linezolid)
- Class IA and III antiarrhythmics (quinidine, procainamide, amiodarone, sotalol)
- Anticholinergic drugs (benztropine, oxybutynin, antihistamines)
- CNS depressants (alcohol, benzodiazepines, opioids, sleep aids)
⚡ Moderate Interactions
- CYP2D6 inhibitors (fluoxetine, paroxetine, bupropion, quinidine)
- CYP1A2 inhibitors (fluvoxamine, ciprofloxacin)
- Antihypertensive drugs
- Thyroid medications
- Cimetidine
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Combining them can cause excessive drowsiness, dizziness, impaired judgement, difficulty breathing, and dangerous changes in heart rhythm. Alcohol can also worsen depression and anxiety, which works against the purpose of treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to amoxapine or other dibenzoxazepine compounds","Use of monoamine oxidase inhibitors (MAOIs) within the past 14 days","Recent heart attack or unstable heart disease","Severe liver disease","Uncontrolled narrow-angle glaucoma","Urinary retention or severe prostate enlargement","History of seizure disorder unless specifically approved by a specialist","Children under 18 years of age"]
⚠️ Warnings & Precautions
["This medicine may increase the risk of suicidal thoughts and behaviour, especially in young adults at the start of treatment or after dose changes. Close monitoring by family and doctor is essential.","It can cause drowsiness and blurred vision. Avoid driving or operating machinery until you know how it affects you.","It can cause dizziness and low blood pressure on standing. Stand up slowly and report fainting episodes.","It can affect heart rhythm. Tell your doctor if you have heart disease or take heart medicines.","It can cause anticholinergic effects such as constipation, dry mouth, and urinary retention. Report severe or persistent symptoms.","It may trigger mania in people with bipolar disorder. Inform your doctor if you have a history of mania.","Do not stop this medicine suddenly, as withdrawal symptoms may occur. Taper gradually under medical supervision.","Avoid alcohol and other central nervous system depressants while taking this medicine.","Use with caution in older adults, who are more sensitive to side effects such as confusion, falls, and heart rhythm changes.","Tell your doctor about all other medicines, supplements, and herbal products you are taking."]
🤱 Lactation Safety
This medicine passes into breast milk and may cause drowsiness, poor feeding, or other effects in a breastfed baby. Breastfeeding while taking this medicine is generally not recommended unless a specialist advises otherwise. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose with this medicine is a medical emergency and can be life-threatening. Symptoms may include severe drowsiness, confusion, agitation, hallucinations, seizures, irregular or fast heartbeat, low blood pressure, and coma. If you suspect an overdose, call emergency services immediately. Do not try to induce vomiting unless instructed by a medical professional. Treatment in hospital may include activated charcoal, ECG monitoring, intravenous fluids, and medications to control seizures and heart rhythm problems. Bring the medicine container to the hospital so the medical team knows exactly what was taken.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, and do not change the dose on your own. Swallow the tablet whole with a glass of water, and if it upsets your stomach, take it with a light meal or snack. Because this medicine can cause drowsiness and blurred vision, avoid driving or operating heavy machinery until you know how it affects you. Stand up slowly from a sitting or lying position to reduce the chance of dizziness. Avoid alcohol completely while taking this medicine, as it can worsen drowsiness and impair your judgement. Tell your doctor about all other medicines, supplements, and herbal products you use, because this medicine can interact with many of them. Do not stop this medicine suddenly, because stopping too quickly can cause withdrawal symptoms such as nausea, headache, and sleep problems. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before continuing this medicine. Keep all follow-up appointments so your doctor can monitor your response, mood, heart rhythm, and blood tests when needed. Store this medicine safely out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more sensitive to the side effects of this medicine, including drowsiness, confusion, dizziness, falls, constipation, urinary retention, and heart rhythm changes. Treatment is usually started at a lower dose and increased slowly. Regular monitoring of heart rhythm, blood pressure, mental status, and kidney function is recommended. The risk of drug interactions is higher in older adults because they often take multiple medicines.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before making any changes to this medicine. The safety of this medicine in pregnancy is not fully established. Your doctor will weigh the benefits of treating depression against the potential risks to the baby. Do not stop this medicine suddenly on your own, as untreated depression can also harm both mother and baby.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthetist that you are taking this medicine before any surgery. It can interact with anaesthetic agents and affect heart rhythm and blood pressure. Your doctor may advise adjusting or temporarily stopping the medicine before surgery. Do not stop it on your own. After surgery, follow your doctor's instructions about when to restart and at what dose.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. It can cause dry mouth, which may increase the risk of dental problems. It can also interact with some medicines used in dentistry, such as certain anaesthetics and sedatives. Your dentist may take extra precautions and recommend frequent sips of water or sugar-free chewing gum for dry mouth.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your coordination. Avoid heavy lifting, high-intensity workouts, or activities that require sharp focus until you know how the medicine affects you. Stand up slowly after exercise to avoid dizziness. Drink plenty of water to stay hydrated. Consult your doctor before starting any new exercise programme.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, especially in the first few weeks. Avoid driving, operating heavy machinery, or performing tasks that require full alertness until you know how it affects you. Inform your employer if your work involves such tasks. You may need to adjust your schedule to take the medicine at times that minimise interference with work. With time and the right dose, most people are able to continue their normal activities.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when it is appropriate to stop, usually after you have been well for a period of time. Stopping is done by gradually reducing the dose over several weeks to avoid withdrawal symptoms and relapse of depression. If you experience severe side effects, contact your doctor immediately; they may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may be necessary for some people to prevent relapse of depression. Regular monitoring is important to check for side effects such as weight gain, changes in blood sugar, heart rhythm problems, and movement disorders. Periodic blood tests and ECG may be recommended. Do not stop the medicine on your own; your doctor will decide when and how to taper it slowly. Long-term use should be reviewed regularly to ensure the benefits continue to outweigh the risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Cognitive behavioural therapy and interpersonal therapy are effective for depression and can be used alone or with medicine.
Evidence: Well-establishedModerate aerobic exercise has been shown to improve mood in mild to moderate depression.
Evidence: Well-establishedBright light therapy can help seasonal affective disorder and some other forms of depression.
Evidence: ModerateMindfulness-based stress reduction may help reduce symptoms of depression and anxiety.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known direct interactions between this medicine and vaccines. However, if you are unwell with a fever or infection, consult your doctor before receiving any vaccine. Keep your vaccination records up to date as part of general health care.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of the reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a doctor's letter explaining why you take this medicine, especially for international travel. Keep the medicine in your hand luggage rather than checked baggage to avoid loss or temperature extremes. Store it at room temperature and away from direct sunlight. If you are crossing time zones, ask your doctor how to adjust your dosing schedule. Do not stop the medicine during travel, and carry enough supply for the entire trip plus a few extra days.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to show some effects within one to two weeks, but the full antidepressant benefit may take four to six weeks or longer. It is important to keep taking it as prescribed and attend follow-up visits.
A: No. Stopping suddenly can cause withdrawal symptoms such as nausea, headache, and sleep problems, and your depression may return. Always taper gradually under your doctor's supervision.
A: No. Alcohol increases drowsiness, dizziness, and the risk of dangerous heart rhythm changes. It can also worsen depression. Avoid alcohol completely while taking this medicine.
A: The safety of this medicine in pregnancy is not fully established. It should only be used if the benefits clearly outweigh the risks, as decided by your doctor. Do not stop or start it without medical advice.
A: If you remember within a short time, take the missed dose. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not take two doses at once.
A: Yes, this medicine can interact with many other medicines, including MAOIs, SSRIs, heart medicines, and anticholinergic drugs. Always tell your doctor about all medicines and supplements you take.
🤔 Common Patient Concerns
🔄 Substitutes for kamipox 50mg tablet
View AllAlternative brands with exact same active ingredient:
-
demolox 50mg tabletPfizer Ltd ₹41.06 13% COSTLIER
-
oxcap 50mg tabletSunrise Remedies Pvt Ltd ₹42.19 16.1% COSTLIER
-
demo 50 tabletD D Pharmaceuticals ₹45.38 24.9% COSTLIER
-
a pine 50mg tabletPsycogen Captab ₹46.78 28.7% COSTLIER
-
amolife 50mg tabletLa Pharmaceuticals ₹58.85 61.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine works immediately like a painkiller.
Fact: This medicine takes several weeks to show its full antidepressant effect. It is not a quick fix. - Myth: You can stop this medicine as soon as you feel better.
Fact: Stopping suddenly can cause withdrawal symptoms and a return of depression. Always taper under medical supervision. - Myth: This medicine is addictive.
Fact: This medicine is not addictive in the way that opioids are, but stopping suddenly can cause withdrawal symptoms. It should be tapered gradually. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided because it increases drowsiness, dizziness, and the risk of heart rhythm problems. - Myth: This medicine can be taken during pregnancy without any risk.
Fact: The safety of this medicine in pregnancy is not fully established. It should only be used if the benefits clearly outweigh the risks, as decided by a doctor.
🔄 Alternative Options
Generic Alternatives
- Amoxapine 50 mg tablet
Brand Alternatives
- axepine 50mg tablet