What is kamipox 100mg tablet used for?

Amoxapine is a tricyclic antidepressant used to treat major depressive disorder. It works by increasing serotonin and norepinephrine in the brain and blocking dopamine receptors. It is available as a 100 mg immediate-release tablet and is taken orally, usually once or twice daily. Common side effects include drowsiness, dry mouth, and dizziness.

Generic Name: Amoxapine (100mg)
Manufacturer: KC Laboratories
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

🇮🇳 kamipox 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा अमोक्सापिन 100 मिलीग्राम की गोली है, जिसका उपयोग मुख्य रूप से अवसाद (डिप्रेशन) के इलाज के लिए किया जाता है। यह ट्राइसाइक्लिक एंटीडिप्रेसेंट (TCA) वर्ग की दवा है। यह मस्तिष्क में सेरोटोनिन और नॉरएपिनेफ्रिन के स्तर को बढ़ाकर मूड को बेहतर बनाने में मदद करती है। इसका उपयोग चिंता के साथ होने वाले अवसाद और कुछ मामलों में मानसिक लक्षणों वाले अवसाद में भी किया जा सकता है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए। इसे अचानक बंद न करें, क्योंकि इससे withdrawal symptoms हो सकते हैं।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि, कब्ज, पेशाब में रुकावट, भूख बढ़ना और वजन बढ़ना शामिल हैं। कुछ लोगों में हृदय की धड़कन अनियमित हो सकती है, दौरे पड़ सकते हैं, या ब्लड प्रेशर कम हो सकता है। गंभीर दुष्प्रभावों में न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम और रक्त विकार शामिल हैं। यदि आपको दिल की धड़कन में अनियमितता, बेहोशी, मांसपेशियों में अकड़न, तेज बुखार, या त्वचा या आँखों का पीला पड़ना दिखे, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। इस दवा के साथ शराब न पिएं क्योंकि इससे नींद और चक्कर आ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अचानक उठने से बचें, धीरे-धीरे उठें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। इस दवा को अचानक बंद न करें। नियमित जांच के लिए डॉक्टर के पास जाएं।

💊 kamipox 100mg tablet Uses & Benefits

[{"condition":"Major depressive disorder","description":"This medicine is used to treat symptoms of depression such as persistent sadness, loss of interest, sleep disturbances, and fatigue.","evidence":"Well-established"},{"condition":"Depression with anxiety","description":"It may help relieve depressive symptoms that occur together with anxiety, though it is not a primary anxiolytic.","evidence":"Moderate"},{"condition":"Depression with psychotic features","description":"Due to its dopamine-blocking properties, it has been used in some patients with psychotic depression, but this is not a first-line use.","evidence":"Limited"}]

Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes prescribed off-label for certain types of chronic nerve pain, though evidence is limited.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Rarely used off-label to prevent migraines, but not a standard treatment.","evidence":"Limited"}]

Primary treatment for: Major depressive disorder

Also treats: Depression with anxiety, Depression with psychotic features

📋 Drug Information

Generic Name(s)	Amoxapine (100mg)
Brand Name	kamipox 100mg tablet
Manufacturer	KC Laboratories
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Tricyclic antidepressants
Route of Administration	Oral
Storage	Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Keep out of reach of children.
Shelf Life	Not established from the available information. Refer to the product packaging for the expiration date.
WHO Guideline	Not established from the available information.
ICMR Guideline	Not established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1

Take this medicine at bedtime to minimize daytime drowsiness.

2

Do not stop this medicine abruptly; your doctor will taper the dose gradually.

3

Avoid alcohol and other CNS depressants while taking this medicine.

4

Stand up slowly to prevent dizziness from orthostatic hypotension.

5

Report any unusual mood changes, suicidal thoughts, or worsening depression immediately.

6

Keep all follow-up appointments and laboratory tests as scheduled.

7

Inform your doctor if you experience involuntary muscle movements or stiffness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅

Persistent sadness

This medicine is commonly prescribed for major depressive disorder.

Likely Use

✅

Loss of interest

This medicine helps improve interest and pleasure in activities.

Likely Use

❌

Fever

This medicine is not a primary fever reducer.

Not Primary

✅

Anxiety

It may help with anxiety associated with depression.

Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmoxapine is rapidly and well absorbed from the gastrointestinal tract after oral administration. Food does not significantly affect the extent of absorption.

DistributionAmoxapine is widely distributed throughout the body, including the central nervous system. It crosses the blood-brain barrier and the placenta, and it is excreted in breast milk.

Protein BindingAmoxapine is approximately 90% bound to plasma proteins.

MetabolismAmoxapine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6. Its major active metabolite is 8-hydroxyamoxapine, which also has antidepressant activity.

Half-LifeThe elimination half-life of amoxapine is approximately 8 to 10 hours, while its active metabolite has a half-life of about 30 hours.

ExcretionAmoxapine and its metabolites are primarily excreted in the urine, with a small amount eliminated in feces.

BioavailabilityThe oral bioavailability of amoxapine is approximately 50% to 60% due to first-pass metabolism.

Onset of ActionThe onset of antidepressant effect typically takes 1 to 2 weeks, but full therapeutic benefit may take 4 to 6 weeks.

Peak Plasma TimePeak plasma concentrations are reached within 1 to 2 hours after oral administration.

Duration of ActionThe duration of action is approximately 24 hours, allowing for once or twice daily dosing.

How It Works

Amoxapine works by inhibiting the reuptake of serotonin and norepinephrine at presynaptic nerve terminals, which increases their concentration in the synaptic cleft and enhances mood. It also blocks dopamine D2 receptors, which may contribute to its antidepressant effect and its potential to cause extrapyramidal side effects. Additionally, it has antagonistic effects at histamine H1, muscarinic acetylcholine, and alpha-1 adrenergic receptors, which explain many of its side effects such as sedation, dry mouth, and orthostatic hypotension.

Mechanism Steps

1

Inhibition of serotonin reuptake: This medicine blocks the serotonin transporter, leading to increased serotonin in the synaptic cleft.

2

Inhibition of norepinephrine reuptake: It also blocks the norepinephrine transporter, increasing norepinephrine availability.

3

Dopamine D2 receptor blockade: This medicine antagonizes dopamine D2 receptors, which may contribute to its antidepressant and antipsychotic effects but also to extrapyramidal side effects.

4

Antagonism at histamine, muscarinic, and alpha-1 receptors: These actions explain sedation, dry mouth, constipation, blurred vision, and orthostatic hypotension.

💡 How to Take kamipox 100mg tablet

Strength: Immediate-release tablet, 100 mg

1Take this medicine exactly as prescribed by your doctor.

2Swallow the tablet whole with a glass of water.

3You may take it with or without food, but taking it with food may reduce stomach upset.

4If you are taking it once daily, take it at bedtime to minimize daytime sedation.

5Do not crush, chew, or break the tablet unless your doctor instructs you to do so.

6Do not stop taking this medicine suddenly without consulting your doctor.

Dosage Information

Adult Dosage	The usual starting dose of amoxapine for adults is 50 mg once daily, which may be increased gradually to 100 mg to 150 mg daily, given in divided doses or as a single bedtime dose. The maximum recommended daily dose is 300 mg, but doses above 100 mg should be given in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment.
Pediatric Dosage	Pediatric dosing is not established from available information. Consult a pediatrician.
Elderly Dosage	Elderly patients are more sensitive to the side effects of amoxapine, especially sedation, anticholinergic effects, and orthostatic hypotension. Start with a lower dose (e.g., 25 mg to 50 mg daily) and titrate slowly. Dose must be individualized by a qualified clinician.
Renal Impairment	Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult a qualified clinician for individualized dosing.
Hepatic Impairment	Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a qualified clinician for individualized dosing.
Maximum Daily Dose	300 mg per day (in divided doses) for adults. Doses above 100 mg should be given in divided doses.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food

Take with meals

Reduces stomach upset.

Grapefruit

Avoid

May increase drug levels.

Alcohol

Avoid

Increases sedation and impairs coordination.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed

→ Take the missed dose as soon as you remember.

💡 Continue with the regular schedule.

📌 More than half the dosing interval has passed

→ Skip the missed dose.

💡 Do not double dose to catch up.

⚠️ Side Effects of kamipox 100mg tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))

Avoid driving or operating machinery until you know how this medicine affects you. If persistent, consult your doctor.

Dry mouth (Common (10-20%))

Sip water frequently, chew sugar-free gum, or use saliva substitutes. Consult your doctor if severe.

Dizziness (Common (5-10%))

Stand up slowly. If dizziness persists or is severe, contact your doctor.

Constipation (Common (5-10%))

Increase dietary fiber and fluid intake. Consult your doctor if constipation persists.

Blurred vision (Common (5-10%))

Usually temporary. If persistent, consult your doctor.

🚨 Serious Side Effects

Cardiac arrhythmias (Rare (<0.1%))

Seek immediate medical attention if you experience palpitations, irregular heartbeat, or fainting.

Seizures (Rare (<0.1%))

Call emergency services if a seizure occurs.

Neuroleptic malignant syndrome (Rare (<0.1%))

Seek immediate medical attention if you develop high fever, muscle rigidity, confusion, or autonomic instability.

Severe hypotension (Rare (<0.1%))

Lie down and call for help if you feel faint or have a sudden drop in blood pressure.

Blood dyscrasias (Rare (<0.1%))

Report unusual bleeding, bruising, sore throat, or fever to your doctor immediately.

⚠️ Rare Side Effects

Tardive dyskinesia

Report involuntary movements of the face, tongue, or limbs to your doctor immediately.

Extrapyramidal symptoms

Contact your doctor if you experience tremors, stiffness, or difficulty moving.

Jaundice

Seek medical attention if you notice yellowing of the skin or eyes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
MAO inhibitors	Major
Fluoxetine	Major
Warfarin	Moderate
Benzodiazepines	Moderate
Anticholinergics	Moderate
Cimetidine	Minor
Grapefruit juice	Minor
Alcohol	Moderate
Antihypertensives	Moderate
Levodopa	Moderate

🚨 Major Interactions

MAO inhibitors
Other tricyclic antidepressants
CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)

⚡ Moderate Interactions

Anticholinergic drugs
CNS depressants (e.g., benzodiazepines, opioids, alcohol)
Antihypertensive drugs

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase sedation, dizziness, and impair your ability to drive or operate machinery. It may also worsen depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to amoxapine or other dibenzoxazepines","Recent myocardial infarction","Uncontrolled narrow-angle glaucoma","Severe liver disease","History of seizure disorders (unless under specialist care)","Concurrent use with MAO inhibitors","Children under 16 years of age"]

⚠️ Warnings & Precautions

["May increase risk of suicidal thoughts and behaviors, especially in children, adolescents, and young adults. Monitor closely.","Can cause sedation and impair ability to drive or operate machinery.","May cause orthostatic hypotension; advise patients to rise slowly.","Can prolong QT interval; use with caution in patients with cardiac disease.","May cause anticholinergic effects; use with caution in patients with glaucoma, constipation, or urinary retention.","Do not stop abruptly; taper gradually to avoid withdrawal symptoms.","May lower seizure threshold; use with caution in patients with a history of seizures.","Can cause neuroleptic malignant syndrome; monitor for symptoms.","May cause blood dyscrasias; monitor blood counts if symptoms occur.","Use with caution in elderly patients due to increased sensitivity to side effects."]

🤱 Lactation Safety

Amoxapine is excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

Overdose of amoxapine can be life-threatening and requires immediate medical attention. Symptoms include severe drowsiness, confusion, agitation, hallucinations, seizures, cardiac arrhythmias, hypotension, and coma. Treatment is supportive and symptomatic, including gastric lavage if within 1-2 hours of ingestion, activated charcoal, management of cardiac arrhythmias, and monitoring in an intensive care unit. There is no specific antidote. Contact emergency services or a poison control center immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless your doctor instructs you to do so. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase sedation and impair your ability to drive or operate machinery. Stand up slowly from a sitting or lying position to prevent dizziness. Inform your doctor about all other medicines, supplements, and herbal products you are taking, especially MAO inhibitors, other antidepressants, antipsychotics, and drugs that affect heart rhythm. Do not stop this medicine suddenly; your doctor will gradually reduce the dose to prevent withdrawal symptoms. Keep all follow-up appointments and laboratory tests as scheduled. Store this medicine at room temperature away from moisture and heat, and keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of amoxapine, especially sedation, anticholinergic effects, and orthostatic hypotension. Start with a lower dose and titrate slowly. Regular monitoring is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking or continuing this medicine. The safety of amoxapine during pregnancy is not fully established, and alternative treatments may be considered.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking amoxapine before any surgery. It may interact with anesthetic agents and affect blood pressure and heart rhythm. Your doctor may advise temporary discontinuation or dose adjustment.

🦷 Dental Procedures

Inform your dentist that you are taking amoxapine, as it can cause dry mouth and may interact with certain dental anesthetics or sedatives. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃

Maintain a regular sleep schedule.

🥗

Engage in regular physical activity as tolerated.

😴

Eat a balanced diet rich in fruits and vegetables.

💧

Avoid alcohol and recreational drugs.

🧘

Practice stress-reduction techniques such as meditation or deep breathing.

🌞

Stay connected with friends and family for emotional support.

🏋️ Exercise Considerations

Exercise is generally safe, but start slowly and avoid overexertion. If you experience dizziness, shortness of breath, or chest pain, stop and consult your doctor. Stay hydrated.

🥗 Diet Recommendations

Include fiber-rich foods to prevent constipation.

Stay well hydrated to reduce dry mouth.

Limit caffeine as it may increase anxiety or insomnia.

Avoid grapefruit and grapefruit juice.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also affect your concentration; take precautions as needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue, they will gradually reduce the dose to prevent withdrawal symptoms. Seek immediate medical attention if you have severe reactions.

📅 Long-Term Use Effects

Long-term use of amoxapine may require periodic monitoring of liver function, kidney function, blood counts, and cardiac status. Some patients may experience weight gain, sexual dysfunction, or tardive dyskinesia with prolonged use. Regular follow-up with your doctor is essential to assess the ongoing benefit and manage any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Psychotherapy

Cognitive behavioral therapy (CBT) can be effective for depression and may complement medicine.

Evidence: Well-established

Exercise

Regular physical activity can help improve mood and reduce depressive symptoms.

Evidence: Well-established

Mindfulness and meditation

These practices can help manage stress and anxiety associated with depression.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between amoxapine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry your medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations regarding prescription medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old woman with major depressive disorder

She started amoxapine 100 mg at bedtime as prescribed. After two weeks, she noticed improvement in her mood and sleep. She experienced dry mouth and drowsiness initially, which decreased over time. She was advised not to stop the medicine suddenly and to keep follow-up appointments.

💡 Lesson: Consistent use and gradual titration improve outcomes. Side effects often diminish with time.

👤 A 60-year-old man with depression and anxiety

He was prescribed amoxapine 50 mg daily, increased to 100 mg after one week. He reported feeling less anxious and more energetic. He was cautioned about orthostatic hypotension and advised to rise slowly. He avoided alcohol and attended regular check-ups.

💡 Lesson: Adhering to safety advice and regular monitoring helps manage side effects and improves treatment success.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It may take 1 to 2 weeks to notice some improvement, but full benefits may take 4 to 6 weeks.

Q: Can I stop this medicine if I feel better?

A: No, do not stop suddenly. Consult your doctor; they will taper the dose gradually to avoid withdrawal symptoms.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol, driving until you know how it affects you, and other CNS depressants. Also avoid grapefruit juice.

Q: Is it safe during pregnancy?

A: Consult your doctor. The safety is not fully established, and it should be used only if the benefit justifies the risk.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

Can I take this medicine long-term?
Will it affect my kidney function?
Can I drive after taking this medicine?
Does it interact with my blood pressure medicine?
What if I miss a dose?
Can I drink alcohol while taking this?
Will I gain weight?
Is it safe during pregnancy?

🔄 Substitutes for kamipox 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

Myth: Amoxapine is a sleeping pill.
Fact: Amoxapine is an antidepressant, not a sleeping pill. It may cause drowsiness as a side effect, but it is not used as a sleep aid.
Myth: You can stop amoxapine as soon as you feel better.
Fact: You should not stop amoxapine suddenly, even if you feel better. Stopping abruptly can cause withdrawal symptoms. Always consult your doctor before stopping.
Myth: Amoxapine is safe to take with alcohol.
Fact: Alcohol should be avoided while taking amoxapine because it can increase sedation and impair your ability to drive or operate machinery.

🔄 Alternative Options

Generic Alternatives

Amoxapine 100 mg tablet

Brand Alternatives

Axepine 100mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Amoxapine","class":"Tricyclic antidepressant (dibenzoxazepine)","primary_use":"Major depressive disorder","sedation":"Moderate to high","anticholinergic_effects":"Moderate to high","cardiac_effects":"Moderate"},{"medicine":"Amitriptyline","class":"Tricyclic antidepressant","primary_use":"Depression, neuropathic pain","sedation":"High","anticholinergic_effects":"High","cardiac_effects":"Moderate to high"},{"medicine":"Nortriptyline","class":"Tricyclic antidepressant","primary_use":"Depression","sedation":"Moderate","anticholinergic_effects":"Moderate","cardiac_effects":"Moderate"}]

Amoxapine 100mg Tablet: Complete Medicine Guide

When to Call Your Doctor IMMEDIATELY

What is kamipox 100mg tablet used for?

🇮🇳 kamipox 100mg tablet के बारे में (Hindi Summary)

💊 kamipox 100mg tablet Uses & Benefits

📋 Drug Information

👨‍⚕️ Doctor's Practical Tips

🔍 Is This Medicine Right for Your Symptom?

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take kamipox 100mg tablet

Dosage Information

Dosage Timeline

🍽️ Food Timing Guide

⏰ What to Do If You Miss a Dose

⚠️ Side Effects of kamipox 100mg tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🔎 Check Your Other Medicines

🛡️ Safety & Warnings

🚫 Contraindications

⚠️ Warnings & Precautions

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

Additional Safety Advice

👴 Special Considerations for Elderly

💡 For Patients Above 65

🤰 Pregnancy Planning (TTC)

🏥 Post-Surgery Considerations

🦷 Dental Procedures

💚 Lifestyle Tips for Better Results

🏋️ Exercise Considerations

🥗 Diet Recommendations

💼 Impact on Daily Work & Life

🛑 When to Stop This Medicine

📅 Long-Term Use Effects

🌿 Non-Medicine Approaches

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

📦 Storage Guide

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✈️ Traveling with This Medicine

💰 Cost Analysis & Savings

👥 Real Patient Stories

💬 Questions Patients Often Ask

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

🔄 Substitutes for kamipox 100mg tablet

🛑 Myths vs. Facts

🔄 Alternative Options

Generic Alternatives

Brand Alternatives

📊 Comparison with Similar Medicines

😊 Was this information helpful?

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