Fenofibrate 160mg + Rosuvastatin 5mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe muscle pain, weakness, or dark brown urine
- Yellowing of the skin or eyes (jaundice)
- Severe upper abdominal pain radiating to the back
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Unusual bleeding or bruising
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is jupiros f 160mg/5mg tablet used for?
This medicine is a combination of fenofibrate 160 mg and rosuvastatin 5 mg used to treat mixed dyslipidemia by lowering LDL cholesterol and triglycerides while raising HDL cholesterol. It is taken once daily with food under medical supervision.
- Generic Name: Fenofibrate (160mg) + Rosuvastatin (5mg)
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jupiros f 160mg/5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फेनोफाइब्रेट 160 मिलीग्राम और रोसुवास्टेटिन 5 मिलीग्राम का संयोजन है, जिसका उपयोग मिश्रित डिस्लिपिडेमिया के इलाज के लिए किया जाता है। यह खराब कोलेस्ट्रॉल (LDL) और ट्राइग्लिसराइड्स को कम करने और अच्छे कोलेस्ट्रॉल (HDL) को बढ़ाने में मदद करती है। यह दवा उन रोगियों के लिए है जिनमें हृदय रोग का खतरा अधिक है और जिनका कोलेस्ट्रॉल आहार और व्यायाम से नियंत्रित नहीं हो पाता। इसे डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, पेट दर्द, कब्ज, मांसपेशियों में दर्द और लीवर एंजाइम में हल्की वृद्धि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें मांसपेशियों की गंभीर क्षति, लीवर की क्षति और अग्न्याशय की सूजन शामिल हो सकती है। अगर आपको असामान्य मांसपेशी दर्द, कमजोरी, गहरे रंग का पेशाब, पीलिया या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को स्वयं कम या ज्यादा न करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। शराब का सेवन न करें क्योंकि इससे लीवर और मांसपेशियों की समस्या का खतरा बढ़ सकता है। गर्भावस्था या स्तनपान के दौरान इस दवा का सेवन न करें। नियमित रूप से लीवर, किडनी और लिपिड प्रोफाइल की जांच कराते रहें। किसी भी असामान्य लक्षण को नजरअंदाज न करें और तुरंत डॉक्टर को बताएं।
💊 jupiros f 160mg/5mg tablet Uses & Benefits
[{"condition":"Mixed dyslipidemia","description":"This medicine is used to lower elevated LDL cholesterol and triglycerides while raising HDL cholesterol in patients with mixed lipid disorders.","evidence":"Well-established"},{"condition":"Hypertriglyceridemia with high LDL cholesterol","description":"It is prescribed when both triglycerides and LDL cholesterol are significantly elevated and lifestyle changes alone are insufficient.","evidence":"Well-established"},{"condition":"Cardiovascular risk reduction","description":"In high-risk patients, this combination helps reduce the risk of heart attack and stroke by improving the overall lipid profile.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diabetic dyslipidemia","description":"Sometimes used in patients with type 2 diabetes who have combined high triglycerides and low HDL cholesterol, but this is not a primary approved indication.","evidence":"Limited"},{"condition":"Non-alcoholic fatty liver disease (NAFLD)","description":"Fenofibrate and statins have been studied for potential benefit in NAFLD, but this combination is not approved for this purpose.","evidence":"Limited"}]
Primary treatment for: Mixed dyslipidemia
Also treats: Hypertriglyceridemia, Hypercholesterolemia, Cardiovascular risk reduction
📋 Drug Information
| Generic Name(s) | Fenofibrate (160mg) + Rosuvastatin (5mg) |
| Brand Name | jupiros f 160mg/5mg tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, away from moisture, heat, and direct light. Do not store in the bathroom. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary lipid-lowering actions. Fenofibrate activates peroxisome proliferator-activated receptor alpha (PPAR-alpha), which increases the expression of genes involved in fatty acid oxidation and lipoprotein lipase activity. This leads to increased breakdown of triglyceride-rich lipoproteins and increased production of apolipoprotein A-I and A-II, resulting in higher HDL cholesterol. Rosuvastatin selectively inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate, a rate-limiting step in cholesterol synthesis in the liver. This inhibition reduces hepatic cholesterol production, which upregulates LDL receptors on hepatocytes and increases clearance of LDL cholesterol from the blood. Together, fenofibrate and rosuvastatin provide a broader improvement in lipid parameters than either agent alone.
Mechanism Steps
💡 How to Take jupiros f 160mg/5mg tablet
Strength: Tablet containing fenofibrate 160 mg and rosuvastatin 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily with food. The dose may be adjusted by your doctor based on your lipid levels, kidney function, and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially muscle and kidney side effects. Dose should be individualized by a qualified clinician based on renal function and overall health. Regular monitoring is recommended. |
| Renal Impairment | Dose adjustment is required in patients with kidney impairment. This medicine is contraindicated in severe renal impairment (eGFR less than 30 mL/min/1.73 m2). Consult your doctor for appropriate dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent elevations of liver enzymes. Use with caution in patients with mild to moderate hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet containing fenofibrate 160 mg and rosuvastatin 5 mg. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jupiros f 160mg/5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Protease inhibitors | Major | |
| Colchicine | Moderate | |
| Antacids | Moderate | |
| Oral contraceptives | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin and other anticoagulants
- Cyclosporine
- Gemfibrozil
- Protease inhibitors (e.g., ritonavir, lopinavir)
⚡ Moderate Interactions
- Colchicine
- Fibrates other than fenofibrate
- Antacids containing aluminum or magnesium
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase the risk of liver damage and may worsen muscle-related side effects. Alcohol can also raise triglyceride levels, which works against the purpose of this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active liver disease or unexplained persistent elevations of serum transaminases.","Severe renal impairment (eGFR less than 30 mL/min/1.73 m2).","Known hypersensitivity to fenofibrate, rosuvastatin, or any component of the formulation.","Gallbladder disease.","Pregnancy and breastfeeding.","Concomitant use with cyclosporine or gemfibrozil."]
⚠️ Warnings & Precautions
["This medicine should be used with caution in patients with a history of liver disease or heavy alcohol use.","Muscle pain, weakness, or dark urine should be reported immediately as it may indicate rhabdomyolysis.","Patients with diabetes may experience changes in blood sugar control; monitor glucose levels.","This medicine may increase the risk of gallstones; report symptoms such as right upper abdominal pain.","Avoid concurrent use with other fibrates or statins unless specifically prescribed.","Use with caution in elderly patients and those with kidney impairment.","Do not use in patients with active peptic ulcer disease or a history of bleeding disorders without medical advice."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding because it is not known whether fenofibrate or rosuvastatin are excreted in human milk. Potential risks to the nursing infant cannot be ruled out. Consult your doctor for alternative treatments if you are breastfeeding.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of suspected overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor liver and kidney function, and watch for signs of muscle toxicity. Hemodialysis is not expected to significantly enhance elimination of fenofibrate or rosuvastatin.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Take the tablet with food to improve absorption and reduce stomach upset. Avoid drinking alcohol while on this medicine because it increases the risk of liver problems and muscle side effects. Tell your doctor about all other medicines, supplements, and herbal products you are taking, especially blood thinners, other cholesterol medicines, and diabetes drugs. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Keep all follow-up appointments for blood tests to check liver enzymes, kidney function, and lipid levels. Report any unexplained muscle pain, weakness, or dark urine immediately. Store the tablets at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to muscle and kidney side effects. Dose should be individualized based on renal function and overall health. Regular monitoring of liver and kidney function is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. Women of childbearing potential should use effective contraception while taking this medicine. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be temporarily stopped before certain procedures due to its effects on liver and muscle. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There is no direct interaction with dental anesthetics, but your dentist should be aware of your medication history, especially if you have bleeding disorders or liver problems.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but if you experience muscle pain, weakness, or cramps during exercise, stop and consult your doctor. This medicine can rarely cause muscle injury, and strenuous exercise may increase that risk. Stay well hydrated during workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness, muscle pain, or fatigue, avoid driving or operating heavy machinery until you feel better. Most people can continue their normal daily activities while taking this medicine.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe muscle pain, liver problems, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor may adjust the dose or switch to a different treatment based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of liver enzymes, kidney function, and lipid levels. It may increase the risk of gallstones, muscle problems, and liver enzyme elevations. Most patients tolerate it well with appropriate monitoring. Your doctor will assess the benefits and risks periodically and may adjust the dose or switch to another treatment if needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight management can help improve lipid levels and complement medicine.
Evidence: Well-establishedStatins, fibrates, ezetimibe, or PCSK9 inhibitors may be used alone or in combination based on your lipid profile.
Evidence: Well-establishedOmega-3 fatty acids, red yeast rice, and plant sterols may have modest lipid-lowering effects.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If traveling across time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Store away from direct sunlight and heat. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within days, but maximum lipid-lowering effects are usually seen after 2 to 4 weeks of consistent use.
A: Do not take other cholesterol-lowering medicines without consulting your doctor, as combining them may increase the risk of side effects.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is not recommended during pregnancy as it may harm the developing baby. Consult your doctor for alternative treatments.
A: No, do not stop taking this medicine without consulting your doctor. High cholesterol is a chronic condition and stopping treatment may cause levels to rise again.
🤔 Common Patient Concerns
🔄 Substitutes for jupiros f 160mg/5mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia fenofibrate+rosuvastatin 160mg/5mg tabletDavaindia Generic Pharmacy ₹32.00 89.5% CHEAPER
-
rosuson-f 160mg/5mg tabletUnison Pharmaceuticals Pvt Ltd ₹41.06 86.6% CHEAPER
-
xor f 160mg/5mg capsuleWonset Healthcare Pvt Ltd ₹60.94 80.1% CHEAPER
-
normalip f 5 tabletTas Med India Pvt Ltd ₹68.29 77.7% CHEAPER
-
rosusim f 160mg/5mg tabletOrsim Pharma ₹70.00 77.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: High cholesterol is a chronic condition. Stopping the medicine may cause levels to rise again. Always consult your doctor before stopping. - Myth: This medicine will cause muscle damage in everyone.
Fact: Serious muscle problems are rare. Most people tolerate the medicine well with regular monitoring. - Myth: Taking this medicine means I can eat whatever I want.
Fact: Diet and exercise are still important. This medicine works best when combined with a healthy lifestyle.
🔄 Alternative Options
Generic Alternatives
- Fenofibrate 160 mg + Rosuvastatin 5 mg tablet (various manufacturers)