Augmentox S 500 mg/125 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe watery diarrhea with fever or abdominal pain
- Yellowing of the skin or eyes
- Blood in stool or vomit
- Severe skin rash with blisters or peeling
- Decreased urine output or swelling in the legs
- Unusual bleeding or bruising
- Persistent high fever despite taking the medicine
If experiencing severe symptoms, call emergency services immediately.
What is jupimox cv 500mg/125mg tablet used for?
This medicine is a combination antibiotic containing amoxycillin and cloxacillin. It is used to treat bacterial infections of the skin, soft tissues, respiratory tract, and dental infections. It works by killing bacteria and should be taken exactly as prescribed.
- Generic Name: Amoxycillin (500mg) + Cloxacillin (125mg)
- Manufacturer: Jupiter Biolabs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jupimox cv 500mg/125mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग त्वचा, मुलायम ऊतक, श्वसन पथ और दांतों के बैक्टीरियल संक्रमण के इलाज के लिए किया जाता है। यह एमोक्सिसिलिन और क्लोक्सासिलिन का संयोजन है, जो बैक्टीरिया को मारकर संक्रमण को रोकता है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करना चाहिए, भले ही लक्षण ठीक हो जाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में परेशानी और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, या यकृत की समस्या हो सकती है। यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर दस्त हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। पूरा कोर्स पूरा करें, बीच में न छोड़ें। एंटासिड या आयरन सप्लीमेंट के साथ 2 घंटे का अंतराल रखें। यदि आपको दाने, सूजन या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से संपर्क करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 jupimox cv 500mg/125mg tablet Uses & Benefits
[{"condition":"Skin and soft tissue infections","description":"Effective against cellulitis, abscesses, infected wounds, and furuncles caused by susceptible staphylococci and streptococci.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Used for community-acquired pneumonia, acute exacerbations of chronic bronchitis, and sinusitis when staphylococcal coverage is required.","evidence":"Established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and pericoronitis caused by mixed oral flora including staphylococci.","evidence":"Established"},{"condition":"Bone and joint infections","description":"May be used for osteomyelitis and septic arthritis caused by susceptible organisms, often as part of a broader regimen.","evidence":"Limited"},{"condition":"Urinary tract infections","description":"Sometimes used for UTIs caused by susceptible bacteria, though other agents are generally preferred.","evidence":"Limited"}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Amoxycillin is part of some H. pylori regimens, but the combination with cloxacillin is not standard.","evidence":"Limited"},{"condition":"Lyme disease","description":"Amoxycillin is used for early Lyme disease, but cloxacillin is not typically included.","evidence":"Limited"}]
Primary treatment for: Bacterial infections (skin, soft tissue, respiratory, dental)
Also treats: Cellulitis, Abscess, Pneumonia, Sinusitis, Dental abscess
📋 Drug Information
| Generic Name(s) | Amoxycillin (500mg) + Cloxacillin (125mg) |
| Brand Name | jupimox cv 500mg/125mg tablet |
| Manufacturer | Jupiter Biolabs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Do not refrigerate unless specified by the manufacturer. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two beta-lactam antibiotics that inhibit bacterial cell wall synthesis. Amoxycillin binds to penicillin-binding proteins (PBPs) and inhibits transpeptidase enzymes, preventing cross-linking of peptidoglycan in the bacterial cell wall. Cloxacillin also binds to PBPs but is resistant to hydrolysis by penicillinase enzymes produced by Staphylococcus aureus, allowing it to act against penicillinase-producing staphylococci. The combination provides broader coverage than either agent alone, targeting both penicillin-susceptible and penicillinase-producing organisms. The inhibition of cell wall synthesis leads to osmotic instability and bacterial lysis, particularly in rapidly dividing bacteria.
Mechanism Steps
💡 How to Take jupimox cv 500mg/125mg tablet
Strength: Each tablet contains Amoxycillin 500 mg and Cloxacillin 125 mg. The tablet is immediate-release and intended for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 6 to 8 hours, depending on the severity and type of infection. The dose may be adjusted by your doctor based on your kidney and liver function, as well as the specific bacteria causing the infection. For skin and soft tissue infections, a common regimen is one tablet every 8 hours for 5 to 10 days. For respiratory tract infections, the duration may be longer. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always complete the full course as prescribed, even if symptoms improve. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. The dose should be individualized based on renal function. Monitor for signs of toxicity. Consult a doctor for appropriate dosing. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance (CrCl) 10-30 mL/min, the dose may be reduced or the interval extended. For CrCl less than 10 mL/min, the dose should be significantly reduced and may be given every 12 to 24 hours. Consult a nephrologist or clinical pharmacist for precise dosing. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment, but use with caution and monitor liver function. Consult a doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose of this medicine is not established from available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jupimox cv 500mg/125mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Tetracyclines | Moderate | |
| Aminoglycosides | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Food (high-fat) | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Allopurinol
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Tetracyclines
- Aminoglycosides
🍷 Alcohol Interaction
Alcohol may worsen stomach upset and diarrhea caused by this medicine. It is advisable to avoid alcohol while taking this medicine, as it can also increase the risk of liver-related side effects. Additionally, alcohol may impair immune function and slow recovery from infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to penicillins or cephalosporins","History of severe allergic reaction (e.g., anaphylaxis) to beta-lactam antibiotics","Infectious mononucleosis (risk of rash)","Concurrent use with tetracyclines (antagonism)","Severe renal impairment (dose adjustment required)"]
⚠️ Warnings & Precautions
["Before starting this medicine, inform your doctor about all your medical conditions and medications.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment; monitor liver function.","May cause false-positive results in urine glucose tests using copper reduction methods.","May cause false-negative results in urine glucose tests using glucose oxidase methods.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","Do not use for viral infections as it is ineffective and promotes resistance.","Ensure adequate fluid intake to prevent crystalluria.","Elderly patients may be more susceptible to side effects; monitor renal function.","Avoid use in patients with a history of penicillin-associated cholestatic jaundice."]
🤱 Lactation Safety
Amoxycillin and cloxacillin are excreted in breast milk in small amounts. They are generally considered safe during breastfeeding, but monitor the infant for diarrhea, thrush, or rash. Consult your doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. In severe cases, neuromuscular hyperexcitability and seizures may occur, especially in patients with renal impairment. Treatment is symptomatic and supportive. Activated charcoal may be used if ingestion is recent. Hemodialysis can remove amoxycillin and cloxacillin from the bloodstream. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take each dose with a full glass of water, preferably with food to reduce stomach upset. Avoid taking antacids or iron supplements within two hours of this medicine, as they may reduce absorption. Inform your doctor if you have kidney or liver problems, or if you are allergic to penicillins or cephalosporins. Do not share this medicine with others. If you develop a rash, swelling, or difficulty breathing, stop the medicine and seek emergency care immediately. If you experience persistent diarrhea, consult your doctor before taking any anti-diarrheal medication. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced renal function and are at higher risk of side effects. Dose adjustment may be needed. Monitor renal function and watch for signs of toxicity.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe, but your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat surgical site infections. Follow your surgeon's instructions carefully and complete the course.
🦷 Dental Procedures
This medicine is often prescribed before or after dental procedures to prevent or treat infection. Inform your dentist if you are allergic to penicillins.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light exercise if you feel well, but avoid strenuous activities if you have fever or fatigue. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you experience these effects. Most people can continue their daily activities, but take rest if you feel unwell.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course or if your doctor advises you to stop. If you experience severe side effects, stop and seek medical advice immediately. Do not stop early even if you feel better, as it may lead to relapse and resistance.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, superinfections such as oral thrush or C. difficile colitis, and rarely, liver or kidney problems. It should only be used for the prescribed duration. Regular monitoring of renal and hepatic function may be required if used for prolonged periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Broader spectrum antibiotic for resistant infections.
Evidence: Well-establishedAlternative for skin infections in penicillin-allergic patients.
Evidence: Well-establishedAlternative for dental and skin infections.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction with vaccines. However, antibiotics may reduce the immune response to live vaccines. Consult your doctor before receiving any live vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and avoid direct sunlight. If crossing time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines in your destination country. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, take it with food to reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is generally considered safe, but consult your doctor before use.
A: It is advisable to avoid alcohol as it may worsen side effects and slow recovery.
🤔 Common Patient Concerns
🔄 Substitutes for jupimox cv 500mg/125mg tablet
View AllAlternative brands with exact same active ingredient:
-
augmentox s 500 mg/125 mg/10 mg tabletNavil Laboratories Pvt Ltd ₹116.95 15.7% CHEAPER
-
Riclav 500mg/125mg TabletElkos Healthcare Pvt Ltd ₹138.00 0.5% CHEAPER
-
amoxlacto cl 625 tabletSpranza Vita Pharmaceutical LLP ₹145.31 4.7% COSTLIER
-
jomoxy-cv 500mg/125mg tabletJonas Pharmaceuticals Pvt Ltd ₹150.00 8.1% COSTLIER
-
senate am 500mg/125mg tabletTikish Pharmaceuticals ₹155.00 11.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full prescribed course to prevent relapse and antibiotic resistance. - Myth: This medicine is safe to take without a prescription.
Fact: This is a prescription medicine. It should only be taken under a doctor's supervision. - Myth: Taking antibiotics with alcohol is always safe.
Fact: Alcohol can worsen side effects like nausea and diarrhea and may reduce the effectiveness of the medicine.
🔄 Alternative Options
Generic Alternatives
- Amoxycillin and Cloxacillin combination (generic)
Brand Alternatives
- Augmentox S 500 mg/125 mg/10 mg Tablet