Selgin Tablet (Selegiline 5 mg): Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe headache with neck stiffness, palpitations, or blurred vision after eating tyramine-rich food.
- Sudden swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Fever with muscle rigidity, sweating, confusion, or agitation, which may suggest serotonin syndrome.
- Chest pain, fast or irregular heartbeat, or fainting.
- Yellowing of the skin or eyes, dark urine, or persistent abdominal pain.
- New hallucinations, severe confusion, or unusual agitation.
- Sudden onset of sleep during driving or other daily activities.
- Uncontrolled vomiting, severe dizziness, or inability to stand up.
If experiencing severe symptoms, call emergency services immediately.
What is jumax 5mg tablet used for?
This medicine is an oral prescription tablet containing selegiline 5 mg, a monoamine oxidase type B inhibitor used mainly in Parkinson's disease. It works by blocking an enzyme that breaks down dopamine in the brain, so more dopamine remains available to control movement. It is usually taken once daily in the morning, with or without food, and must be used under medical supervision because it interacts with many medicines and with tyramine-rich foods.
- Generic Name: Selegiline (5mg)
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jumax 5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेलेजिलीन 5 मिलीग्राम की एक प्रिस्क्रिप्शन गोली है, जिसका उपयोग मुख्य रूप से पार्किंसन रोग के इलाज में किया जाता है। यह मस्तिष्क में डोपामिन को तोड़ने वाले एंजाइम को रोकती है, जिससे मस्तिष्क में डोपामिन की मात्रा अधिक समय तक बनी रहती है और कंपन, अकड़न तथा चलने में धीमापन जैसे लक्षण कम होते हैं। इसे अक्सर लेवोडोपा के साथ या शुरुआती पार्किंसन रोग में अकेले दिया जाता है। यह दवा केवल डॉक्टर की सलाह से लेनी चाहिए, क्योंकि यह कई अन्य दवाओं और कुछ खाद्य पदार्थों के साथ प्रतिक्रिया कर सकती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, मुँह सूखना, चक्कर आना, खड़े होने पर सिर घूमना, नींद न आना और सपने देखना शामिल हैं। कुछ लोगों में लेवोडोपा के साथ लेने पर शरीर में अनियंत्रित हरकतें हो सकती हैं। गंभीर लेकिन दुर्लभ दुष्प्रभावों में तेज़ सिरदर्द, धड़कन तेज़ होना, सीने में दर्द, भ्रम, मतिभ्रम और रक्तचाप का खतरनाक रूप से बढ़ जाना शामिल है। अगर ऐसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर द्वारा बताई गई मात्रा में ही लें और अपने आप मात्रा न बढ़ाएँ या बंद न करें। इसे पानी के साथ निगलें, और अगर पेट खराब लगे तो हल्के नाश्ते के साथ लें। पुरानी चीज़, प्रोसेस्ड मीट, सोया सॉस, ब्रॉड बीन और टैप बियर जैसे टायरामिन युक्त खाद्य पदार्थों से बचें, क्योंकि इनसे रक्तचाप खतरनाक रूप से बढ़ सकता है। कोई भी नई दवा, हर्बल उत्पाद या सप्लीमेंट शुरू करने से पहले डॉक्टर से सलाह लें। गाड़ी चलाने या मशीन चलाने से पहले सावधानी बरतें, क्योंकि इससे चक्कर या नींद आ सकती है। सर्जरी से पहले सर्जन और एनेस्थेटिस्ट को इस दवा के बारे में ज़रूर बताएँ।
💊 jumax 5mg tablet Uses & Benefits
[{"condition":"Parkinson's disease as add-on therapy","description":"This medicine is added to levodopa or levodopa plus carbidopa to reduce motor fluctuations and to smooth out the wearing-off effect that many people experience as Parkinson's disease progresses.","evidence":"Well-established"},{"condition":"Early Parkinson's disease as monotherapy","description":"In selected people with mild early Parkinson's disease, this medicine may be used alone to delay the need for levodopa, although the benefit is usually modest.","evidence":"Established"},{"condition":"Parkinson's disease with levodopa-induced fluctuations","description":"This medicine can reduce the duration of off periods and improve daily functioning in people whose response to levodopa has become unpredictable.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Depression","description":"Selegiline has been studied in depression, but the oral 5 mg tablet is not the usual formulation used for this purpose, and any such use must be decided by a specialist psychiatrist.","evidence":"Limited"},{"condition":"Attention deficit hyperactivity disorder","description":"Small studies have explored MAO-B inhibitors in attention deficit hyperactivity disorder, but this is not an approved use of this medicine.","evidence":"Limited"},{"condition":"Restless legs syndrome","description":"Some clinicians have tried this medicine in restless legs syndrome, but the evidence is weak and other treatments are preferred.","evidence":"Limited"}]
Primary treatment for: Parkinson's disease
Also treats: Levodopa-induced motor fluctuations, Early Parkinson's disease with mild symptoms, Parkinson's disease with wearing-off effect
📋 Drug Information
| Generic Name(s) | Selegiline (5mg) |
| Brand Name | jumax 5mg tablet |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | MAO-B Inhibitors |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15 and 30 degrees Celsius, in a dry place away from direct sunlight and moisture. Keep the tablets in their original container with the lid tightly closed, and keep them out of the reach of children and pets. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture, depending on the pack. Always check the expiry date printed on the pack and do not use the tablets after that date. |
| WHO Guideline | The World Health Organization does not publish a specific recommendation for this medicine alone. Parkinson's disease treatment guidelines generally list monoamine oxidase type B inhibitors such as this medicine as an option for early disease or as add-on therapy, but the choice must be made by a qualified clinician. |
| ICMR Guideline | The Indian Council of Medical Research has not issued a specific standalone guideline for this medicine. Indian neurology practice generally follows international Parkinson's disease guidelines, and this medicine is used as an add-on to levodopa or occasionally alone in early disease under specialist supervision. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively and irreversibly blocking the enzyme monoamine oxidase type B, which is the main enzyme that breaks down dopamine in the brain. When this enzyme is blocked, dopamine that is already present in the brain is not destroyed as quickly, so more dopamine remains available to stimulate nerve cells in the parts of the brain that control movement. At the 5 mg dose used in this tablet, the effect is described as selective for monoamine oxidase type B, which means that the breakdown of tyramine and other monoamines is affected to a much smaller degree than with older non-selective monoamine oxidase inhibitors. Even so, the selectivity is dose-dependent and can be lost if the dose is increased, which is one reason why the dose must never be increased without medical advice. This medicine may also have a mild effect in protecting brain cells from damage, although this possible neuroprotective action is not fully proven.
Mechanism Steps
💡 How to Take jumax 5mg tablet
Strength: Immediate-release oral tablet containing selegiline 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 mg taken once daily, often in the morning, either alone in early Parkinson's disease or as an add-on to levodopa. Some clinicians may advise 5 mg twice daily, but the total daily dose should not normally exceed 10 mg, because higher doses can lose selectivity for monoamine oxidase type B and increase the risk of a dangerous rise in blood pressure. When this medicine is added to levodopa, the levodopa dose is often reduced by about 10 to 30 percent to prevent involuntary movements. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medicines being taken. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults can usually take the same 5 mg daily dose, but they are more sensitive to dizziness, confusion, hallucinations, and low blood pressure. Start with the lowest effective dose, review all other medicines carefully, and monitor blood pressure and mental state at regular intervals. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Mild to moderate kidney impairment usually does not require a dose change, but this medicine and its metabolites are excreted in the urine, so caution is advised in severe kidney impairment. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | This medicine is broken down in the liver, so people with mild to moderate liver impairment should be monitored closely for side effects. This medicine is contraindicated in severe liver impairment. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 10 mg, usually given as 5 mg twice daily. Doses above this level are not recommended because selectivity for monoamine oxidase type B is lost and the risk of a hypertensive reaction increases. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jumax 5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Phenelzine | Major | |
| Tranylcypromine | Major | |
| Fluoxetine | Major | |
| Sertraline | Major | |
| Tramadol | Major | |
| Meperidine | Major | |
| Pseudoephedrine | Major | |
| Levodopa | Moderate | |
| Carbamazepine | Moderate | |
| Ciprofloxacin | Moderate |
🚨 Major Interactions
- Other monoamine oxidase inhibitors including phenelzine, tranylcypromine, and moclobemide
- Selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors
- Meperidine and other opioid painkillers such as tramadol
- Levodopa
- Sympathomimetic medicines such as pseudoephedrine and phenylephrine
⚡ Moderate Interactions
- Tricyclic antidepressants such as amitriptyline
- Carbamazepine
- Oral contraceptives containing ethinylestradiol
- Ciprofloxacin and other strong CYP1A2 inhibitors
🍷 Alcohol Interaction
Alcohol should be avoided or kept to a minimum while taking this medicine. Alcohol can worsen dizziness, drowsiness, and low blood pressure, and some alcoholic drinks, especially tap beer and red wine, contain tyramine that can raise blood pressure. If you do drink alcohol, discuss it with your clinician first and never drink heavily.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to selegiline or any other ingredient in this tablet.","Use of another monoamine oxidase inhibitor within the previous 14 days.","Active peptic ulcer disease.","Pheochromocytoma, a tumour of the adrenal gland.","Severe liver impairment.","Uncontrolled high blood pressure.","Use with meperidine or other opioids that can trigger serotonin syndrome.","Use with sympathomimetic medicines such as pseudoephedrine."]
⚠️ Warnings & Precautions
["Do not stop this medicine suddenly, because abrupt withdrawal can cause a serious reaction with fever, muscle rigidity, and unstable blood pressure.","Avoid foods high in tyramine, because they can trigger a dangerous rise in blood pressure.","Tell your clinician about all other medicines, including antidepressants, painkillers, and cold remedies, before starting this medicine.","Use caution when driving or operating machinery until you know how this medicine affects you.","Report any new or worsening confusion, hallucinations, or unusual sleepiness to your clinician.","People with a history of peptic ulcer, heart disease, or irregular heartbeat need careful assessment before and during treatment.","This medicine may increase the effects of levodopa, so the levodopa dose may need to be reduced.","Tell your surgeon and anaesthetist that you are taking this medicine before any planned operation."]
🤱 Lactation Safety
This medicine passes into breast milk, and the effects on a breastfed baby are not well established. Breastfeeding is generally not recommended while taking this medicine unless a specialist advises otherwise after weighing the benefits and risks.
💊 Overdose Management
An overdose of this medicine can cause severe agitation, confusion, hallucinations, fast or irregular heartbeat, a dangerous rise in blood pressure, fever, and muscle rigidity. If an overdose is suspected, contact emergency services or go to the nearest hospital immediately. Do not try to make yourself vomit unless a healthcare professional tells you to. Treatment in hospital is supportive and may include monitoring of blood pressure, heart rhythm, and body temperature, along with medicines to control agitation and blood pressure if needed. Take the medicine container with you so that the medical team knows exactly what was taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided that it is not almost time for your next dose. If it is nearly time for the next dose, skip the missed dose and continue with your regular schedule. Never take two doses at the same time to make up for a missed dose, because this can increase the risk of side effects. If you are unsure what to do, contact your clinician or pharmacist for advice.
Additional Safety Advice
Take this medicine exactly as your clinician has prescribed, and never change the dose without medical advice. Swallow the tablet with water, and if it upsets your stomach, take it with a light meal or snack. Avoid foods that are very high in tyramine, such as aged cheese, cured meats, fermented soy products, broad bean pods, and tap beer, because these can trigger a dangerous rise in blood pressure. Tell every doctor, dentist, and pharmacist who treats you that you are taking this medicine, because it interacts with many common medicines including certain antidepressants, painkillers, and cold remedies. Do not start any new medicine, herbal product, or supplement without checking with your clinician first. Keep a written list of all your medicines with you at all times. Do not drive or operate heavy machinery until you know how this medicine affects you, because it can cause dizziness or sudden sleepiness. If you are scheduled for surgery, tell your surgeon and anaesthetist well in advance, because this medicine may need to be adjusted before the procedure. Store the tablets in their original container, away from heat, moisture, and direct sunlight, and keep them out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to experience dizziness, confusion, hallucinations, and low blood pressure while taking this medicine. The dose should be kept as low as possible, and blood pressure, mental state, and sleep should be reviewed at every visit. Falls are a particular concern, so home safety should be assessed. Older adults often take many other medicines, so a full medication review is essential before and during treatment with this medicine.
🤰 Pregnancy Planning (TTC)
If you are planning a pregnancy, discuss this medicine with your clinician before you conceive. Human data on the use of this medicine in pregnancy are limited, and the decision to continue or change treatment should be made by a specialist who can weigh the benefits and risks for both mother and baby. Do not stop this medicine suddenly on your own, because abrupt withdrawal can be dangerous.
🏥 Post-Surgery Considerations
Tell your surgeon and anaesthetist that you are taking this medicine well before any planned operation. This medicine can interact with anaesthetic medicines and with painkillers used after surgery, and it may need to be adjusted or temporarily stopped under medical supervision. After surgery, your Parkinson's medicines should be restarted as soon as possible, because missing doses can cause a serious worsening of symptoms. Pain relief should be chosen carefully, and medicines such as meperidine and tramadol should be avoided.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. Some local anaesthetics and painkillers used in dentistry can interact with this medicine, and medicines containing sympathomimetics should be avoided. If you need a procedure under sedation or general anaesthesia, your dentist should coordinate with your clinician. Keep your medicine list with you and do not stop this medicine on your own before a dental appointment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged in Parkinson's disease, but take extra care while your body adjusts to this medicine. Dizziness or light-headedness on standing can increase the risk of falls, so stand up slowly and use support if needed. Avoid strenuous exercise in hot weather, because this medicine can affect blood pressure and body temperature regulation. If you feel unusually sleepy or dizzy during exercise, stop and rest, and tell your clinician. Balance exercises and physiotherapy can be very helpful, but they should be started gradually.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can improve movement and daily functioning, which may help you continue your work and hobbies. However, it can cause dizziness, sudden sleepiness, or confusion, especially in the first few weeks or after a dose change. Do not drive or operate heavy machinery until you know how this medicine affects you. If your job involves heights, heavy machinery, or safety-critical tasks, discuss it with your clinician. Keep your employer informed if you need adjustments, and carry your medicine list with you at all times.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your clinician may decide to reduce or stop it if you develop serious side effects, if the medicine is no longer helping, or if you need to start another medicine that interacts with it. When stopping, the dose is usually reduced gradually over days to weeks to avoid a withdrawal reaction with fever, muscle rigidity, confusion, and unstable blood pressure. If you experience any of these symptoms after stopping, seek medical help immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated when the dose is kept within the recommended range and dietary advice is followed. Over time, some people develop involuntary movements, hallucinations, or confusion, especially when this medicine is combined with levodopa. Blood pressure, mood, sleep, and mental state should be reviewed at regular intervals. Liver function may be checked if symptoms suggest liver problems. The dose of levodopa may need to be adjusted over time as Parkinson's disease progresses. This medicine should not be stopped suddenly, and any plan to reduce or stop it must be made slowly with your clinician.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Structured physiotherapy can improve balance, gait, and flexibility in Parkinson's disease and can complement this medicine.
Evidence: Well-establishedOccupational therapy helps with daily activities, home safety, and adapting to changes in movement.
Evidence: Well-establishedSpeech therapy can help with voice and swallowing difficulties that may occur in Parkinson's disease.
Evidence: EstablishedA surgical option for selected people with advanced Parkinson's disease whose symptoms are not well controlled by medicines.
Evidence: Well-established for selected patientsA fresh, balanced diet, regular exercise, and good sleep hygiene support overall brain health and can improve quality of life.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. However, if you are due for surgery or a procedure, tell your clinician and the vaccination team about all your medicines. If you develop a fever or infection after vaccination, do not change your Parkinson's medicines on your own; contact your clinician for advice.
📦 Storage Guide
✅ DO
Store at room temperature between 15 and 30 degrees Celsius.
❌ DON'T
Do not refrigerate unless the label specifically says so.
✅ DO
Keep the tablets in their original container with the lid tightly closed.
❌ DON'T
Do not transfer the tablets to an unmarked container.
✅ DO
Keep the container away from direct sunlight and moisture.
❌ DON'T
Do not store the tablets in a bathroom cabinet or near a sink.
✅ DO
Keep the medicine out of the reach of children and pets.
❌ DON'T
Do not leave loose tablets on a table or bedside stand.
✅ DO
Check the expiry date before each use.
❌ DON'T
Do not use the tablets after the expiry date.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original labelled container along with a copy of your prescription and a letter from your doctor explaining why you need it. Keep enough supply for the whole trip plus a few extra days in case of delays. Store the tablets in a cool, dry place away from direct sunlight, and do not leave them in a hot car or in checked luggage. If you are crossing time zones, ask your clinician how to adjust the timing of your doses so that you do not take two doses too close together. Be careful with local foods while travelling, because some regional dishes may be high in tyramine. Check the customs rules of your destination country for controlled or prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some people notice an improvement in Parkinson's symptoms within a few days, but the full benefit usually takes several weeks. Your clinician will review your response at follow-up visits.
A: Yes, this medicine is often used together with levodopa. However, the levodopa dose may need to be reduced to prevent involuntary movements, so this must be managed by your clinician.
A: Avoid or limit aged cheese, cured and fermented meats, fermented soy products, broad bean pods, and tap beer, because these are high in tyramine and can cause a dangerous rise in blood pressure.
A: No. Stopping suddenly can cause a serious withdrawal reaction with fever, muscle rigidity, confusion, and unstable blood pressure. Always ask your clinician before stopping or changing the dose.
A: Human data are limited, so this medicine should only be used in pregnancy if a specialist decides that the benefit clearly outweighs the risk.
A: Yes, many antidepressants interact dangerously with this medicine and can cause serotonin syndrome. Always tell your clinician about every medicine you take.
A: It is best to avoid or strictly limit alcohol, because it can worsen dizziness and blood pressure changes, and some drinks contain tyramine.
A: If it is not almost time for your next dose, take the missed dose as soon as you remember. If it is nearly time, skip it and continue your regular schedule. Never double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for jumax 5mg tablet
View AllAlternative brands with exact same active ingredient:
-
selerin 5mg tabletCipla Ltd ₹30.47 12% CHEAPER
-
elegelin 5mg tabletSun Pharmaceutical Industries Ltd ₹34.99 1.1% COSTLIER
-
jumex 5mg tabletSanofi India Ltd ₹49.26 42.3% COSTLIER
-
selgelin 5mg tabletD D Pharmaceuticals ₹71.50 106.5% COSTLIER
-
selgin tabletIntas Pharmaceuticals Ltd ₹96.56 178.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped as soon as Parkinson's symptoms improve.
Fact: This medicine should never be stopped suddenly, because abrupt withdrawal can cause a serious reaction with fever, muscle rigidity, and unstable blood pressure. Any change must be made slowly under medical supervision. - Myth: This medicine is a cure for Parkinson's disease.
Fact: This medicine helps to control symptoms but does not cure Parkinson's disease. It works best as part of a broader treatment plan that includes other medicines, physiotherapy, and lifestyle measures. - Myth: Dietary restrictions are not needed with this medicine.
Fact: Foods rich in tyramine, such as aged cheese and cured meats, can trigger a dangerous rise in blood pressure while taking this medicine, so dietary advice from your clinician must be followed. - Myth: This medicine can be taken with any antidepressant.
Fact: Many antidepressants interact dangerously with this medicine and can cause serotonin syndrome. Always check with your clinician before combining any antidepressant. - Myth: A higher dose will always give better symptom control.
Fact: Doses above 10 mg daily are not recommended, because the medicine loses its selectivity and the risk of a hypertensive reaction increases.
🔄 Alternative Options
Generic Alternatives
- Selegiline 5 mg immediate-release tablet
Brand Alternatives
- Selgin tablet