Altidol Plus 50mg/500mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Seizures or convulsions
- Slow or shallow breathing
- Confusion or extreme drowsiness
If experiencing severe symptoms, call emergency services immediately.
What is jotram p 50mg/500mg tablet used for?
This medicine is a combination of tramadol and paracetamol used for short-term relief of moderate to severe pain. It works by blocking pain signals in the brain and reducing fever. It should be taken exactly as prescribed and is not for long-term use.
- Generic Name: Tramadol (50mg) + Paracetamol (500mg)
- Manufacturer: Jaqson Healthcare Pvt. Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jotram p 50mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ट्रामाडोल और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह सर्जरी, दांत निकालने, या चोट के बाद होने वाले दर्द में राहत देती है। यह दवा दर्द को कम करने के लिए मस्तिष्क और रीढ़ की हड्डी में काम करती है। इसे केवल डॉक्टर के निर्देशानुसार ही लें और लंबे समय तक न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, चक्कर आना, नींद आना, सिरदर्द, कब्ज, मुंह सूखना और पसीना आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें दौरे, सीरोटोनिन सिंड्रोम, गंभीर एलर्जी, सांस लेने में कठिनाई और लीवर की क्षति शामिल हो सकती है। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। निर्धारित मात्रा से अधिक न लें और लंबे समय तक न लें। इस दवा के साथ शराब न पिएं क्योंकि इससे लीवर की क्षति और नींद बढ़ सकती है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 jotram p 50mg/500mg tablet Uses & Benefits
[{"condition":"Moderate to severe acute pain","description":"This medicine is used for short-term relief of moderate to severe pain, such as after surgery, dental procedures, or musculoskeletal injuries.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"It helps manage pain following surgical procedures when non-opioid analgesics are insufficient.","evidence":"Well-established"},{"condition":"Dental pain","description":"Used for relief of moderate to severe dental pain, including after tooth extraction.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"May be prescribed for acute back pain, sprains, and strains when other treatments are inadequate.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Chronic pain syndromes","description":"Sometimes used off-label for chronic pain conditions like fibromyalgia or neuropathic pain, but evidence is limited and risks of long-term use must be considered.","evidence":"Limited"},{"condition":"Migraine","description":"Occasionally used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"}]
Primary treatment for: Moderate to severe acute pain
Also treats: Postoperative pain, Dental pain, Musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Tramadol (50mg) + Paracetamol (500mg) |
| Brand Name | jotram p 50mg/500mg tablet |
| Manufacturer | Jaqson Healthcare Pvt. Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two analgesics with different mechanisms. Tramadol is a centrally acting opioid analgesic that binds to mu-opioid receptors and also inhibits the reuptake of norepinephrine and serotonin, which contributes to its pain-relieving effect. Paracetamol acts primarily in the central nervous system to reduce pain and fever, likely by inhibiting prostaglandin synthesis in the brain and interfering with pain signal transmission. Together, they provide enhanced pain relief through complementary pathways.
Mechanism Steps
💡 How to Take jotram p 50mg/500mg tablet
Strength: Each tablet contains tramadol hydrochloride 50 mg and paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (tramadol 50 mg and paracetamol 500 mg) taken orally every 4 to 6 hours as needed for pain. The maximum recommended dose is 8 tablets in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not recommended for children under 12 years of age. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of tramadol, especially respiratory depression and dizziness. Dose reduction may be necessary. The dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, the dose may need to be reduced and the dosing interval extended. Consult a qualified clinician for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, the dose should be reduced and the dosing interval extended. Avoid use in severe hepatic impairment. Consult a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is 8 tablets (tramadol 400 mg and paracetamol 4000 mg) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jotram p 50mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| SSRIs | Major | |
| Warfarin | Major | |
| Alcohol | Major | |
| Benzodiazepines | Moderate | |
| Carbamazepine | Moderate | |
| Quinidine | Moderate | |
| Anticholinergics | Minor | |
| Metoclopramide | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- MAO inhibitors
- SSRIs, SNRIs, tricyclic antidepressants
- Warfarin
- Alcohol
⚡ Moderate Interactions
- CNS depressants (benzodiazepines, opioids, sleep aids)
- Carbamazepine
- Quinidine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and enhances the sedative and respiratory depressant effects of tramadol, which can be dangerous.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to tramadol or paracetamol","Severe respiratory depression or severe obstructive airway disease","Acute or severe asthma","Severe liver disease","Uncontrolled epilepsy","Concurrent use of MAO inhibitors or within 14 days of stopping them","Children under 12 years of age","Post-operative pain management in children under 18 years following tonsillectomy or adenoidectomy"]
⚠️ Warnings & Precautions
["Risk of dependence and withdrawal with prolonged use.","May impair mental and physical abilities; avoid driving or operating machinery.","Use with caution in elderly patients due to increased risk of falls and respiratory depression.","Avoid in patients with a history of substance abuse.","Do not exceed the recommended dose of paracetamol to avoid liver damage.","Use with caution in patients with kidney or liver impairment.","May increase risk of seizures, especially in patients with epilepsy or those taking other seizure-threshold-lowering drugs.","Serotonin syndrome can occur, especially with concomitant serotonergic drugs."]
🤱 Lactation Safety
Tramadol and paracetamol are excreted in breast milk. Limited data suggest that short-term use may be acceptable, but consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose can cause severe liver damage from paracetamol and respiratory depression, seizures, and coma from tramadol. Seek immediate medical attention. Treatment includes supportive care, activated charcoal if within 1-2 hours, and acetylcysteine for paracetamol toxicity. Naloxone may reverse opioid effects but can precipitate seizures in tramadol overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than prescribed. Avoid alcohol while taking this medicine because it can increase drowsiness and the risk of liver damage. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have liver or kidney disease, breathing problems, or a history of seizures or drug abuse. Do not take other medicines containing paracetamol while on this medicine to avoid overdose. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of side effects such as dizziness, drowsiness, respiratory depression, and falls. Dose reduction may be necessary. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Tramadol and paracetamol should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed for postoperative pain. Follow your surgeon's instructions carefully. Do not drive or operate machinery until fully recovered and cleared by your doctor.
🦷 Dental Procedures
This medicine can be used for dental pain after procedures like tooth extraction. Inform your dentist about all medicines you are taking. Avoid alcohol-containing mouthwashes if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that could worsen your pain while taking this medicine. Consult your doctor or physiotherapist before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also affect your concentration, so take precautions at work.
🛑 When to Stop This Medicine
Stop taking this medicine when your pain is controlled or as advised by your doctor. Do not stop suddenly if you have been taking it for more than a few days, as withdrawal symptoms may occur. Consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to dependence, tolerance, and withdrawal symptoms. It may also increase the risk of liver damage from paracetamol and serotonin syndrome from tramadol. Regular monitoring of liver and kidney function may be required. It is not recommended for chronic pain management without specialist supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage pain and improve function for musculoskeletal conditions.
Evidence: Well-establishedMay be used for mild to moderate pain if not contraindicated.
Evidence: Well-establishedCan provide local pain relief for muscle and joint pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing intervals as advised by your doctor. Check local customs regulations regarding controlled substances.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking this medicine.
A: This medicine is for short-term use only, usually for a few days to a week. Consult your doctor for longer use.
A: Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.
A: Tramadol can cause dependence, so it should be used only as prescribed and for a short duration.
🤔 Common Patient Concerns
🔄 Substitutes for jotram p 50mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
Tramanat Plus TabletNature Biotech ₹23.44 57.1% CHEAPER
-
Tramnom-P 50mg/500mg TabletAcinom Healthcare ₹34.00 37.7% CHEAPER
-
scudol p 50mg/500mg tabletScutage Pharmaceuticals ₹35.63 34.7% CHEAPER
-
aldol tp 50mg/500mg tabletAltar Healthcare Pvt Ltd ₹37.50 31.3% CHEAPER
-
dolin plus tabletSerin Formulations Pvt Ltd ₹37.97 30.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Altidol Plus is safe to take for any type of pain.
Fact: It is only for moderate to severe acute pain and should not be used for minor aches or long-term pain without medical supervision. - Myth: Altidol Plus is not addictive.
Fact: Tramadol, one of its ingredients, can cause dependence and withdrawal, so it should be used only as prescribed. - Myth: You can drink alcohol while taking Altidol Plus.
Fact: Alcohol increases the risk of liver damage and severe sedation, so it should be avoided.
🔄 Alternative Options
Generic Alternatives
- Tramadol 50 mg + Paracetamol 500 mg tablet
Brand Alternatives
- Ultracet
- Tramazac
- Zydol
- Contramal
- Tramal