jardiance 10mg tablet - Empagliflozin (10mg) medicine

Gibtulio 10mg Tablet: Comprehensive Medicine Guide

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🏭 Boehringer Ingelheim 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 27, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended during pregnancy. Limited data on use in pregnant women. Use only if potential benefit justifies potential risk to the fetus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Nausea, vomiting, or abdominal pain with fruity-smelling breath
  • Severe pain, redness, or swelling in the genital area with fever
  • Fever, chills, or pain in the lower back or side
  • Dizziness, lightheadedness, or rapid heartbeat
  • Unusual bone pain or fractures
  • Pain, numbness, or discoloration in the legs or feet
  • Decreased urine output or swelling in the legs

If experiencing severe symptoms, call emergency services immediately.

What is jardiance 10mg tablet used for?

This medicine is an SGLT2 inhibitor used to treat type 2 diabetes by helping the kidneys remove excess glucose through urine. It also reduces cardiovascular and heart failure risks in certain patients.

  • Generic Name: Empagliflozin (10mg)
  • Manufacturer: Boehringer Ingelheim
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 jardiance 10mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा टाइप 2 डायबिटीज के इलाज के लिए इस्तेमाल की जाती है। यह शरीर से अतिरिक्त शर्करा को मूत्र के माध्यम से बाहर निकालने में मदद करती है। इसके अलावा, यह हृदय रोग और हृदय विफलता के जोखिम को कम करने में भी मदद कर सकती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मूत्र मार्ग में संक्रमण, जननांग में फंगल संक्रमण, और बार-बार पेशाब आना शामिल हैं। कुछ रोगियों को मतली, प्यास, या चक्कर आ सकते हैं। गंभीर दुष्प्रभावों में कीटोएसिडोसिस और गंभीर संक्रमण शामिल हैं।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी किडनी या लीवर की बीमारी, कम नमक वाली डाइट, या मूत्र मार्ग संक्रमण के इतिहास के बारे में बताएं। पर्याप्त पानी पिएं। जननांग स्वच्छता बनाए रखें। कीटोएसिडोसिस के लक्षण दिखने पर तुरंत डॉक्टर से मिलें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 jardiance 10mg tablet Uses & Benefits

[{"condition":"Type 2 Diabetes Mellitus","description":"Improves glycemic control by increasing urinary glucose excretion, leading to reduced blood sugar levels.","evidence":"Well-established"},{"condition":"Cardiovascular Risk Reduction","description":"Reduces the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.","evidence":"Well-established"},{"condition":"Heart Failure Risk Reduction","description":"Reduces the risk of hospitalization for heart failure in adults with type 2 diabetes and cardiovascular risk factors.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Weight Loss","description":"May promote modest weight loss due to caloric loss through urine, but not approved for this indication.","evidence":"Limited"},{"condition":"Non-Alcoholic Fatty Liver Disease","description":"Some studies suggest potential benefit, but not FDA-approved for this use.","evidence":"Limited"}]

Primary treatment for: Type 2 Diabetes Mellitus

Also treats: Cardiovascular disease, Heart failure, Chronic kidney disease

📋 Drug Information

Generic Name(s)Empagliflozin (10mg)
Brand Namejardiance 10mg tablet
ManufacturerBoehringer Ingelheim
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassSGLT2 inhibitors
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place. Keep in original container. Protect from moisture and light.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning.
2
Stay well hydrated to prevent dehydration and urinary tract infections.
3
Maintain good genital hygiene to reduce the risk of fungal infections.
4
Monitor your blood sugar levels regularly as advised by your doctor.
5
Report any signs of ketoacidosis such as nausea, vomiting, or fruity-smelling breath immediately.
6
Avoid excessive alcohol consumption while taking this medicine.
7
Inform your doctor if you are planning to become pregnant or are breastfeeding.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar
This medicine is commonly prescribed for this.
Likely Use
✅
Frequent urination
This medicine may cause increased urination as a side effect.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing oral administration, this medicine is rapidly absorbed. The absolute bioavailability is approximately 78%.
DistributionThe apparent volume of distribution is approximately 73.8 L. It is extensively bound to plasma proteins.
Protein BindingApproximately 86.2% bound to plasma proteins.
MetabolismThis medicine is primarily metabolized by glucuronidation via UGT1A3, UGT1A8, UGT1A9, and UGT2B7 enzymes. No major oxidative metabolites are formed.
Half-LifeThe elimination half-life is approximately 12.4 hours.
ExcretionThis medicine is eliminated primarily via urine (54.4%) and feces (41.2%). The majority is excreted as unchanged drug or glucuronide conjugates.
BioavailabilityApproximately 78%
Onset of ActionThe onset of blood glucose lowering effect is within 1-2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 1.5 hours after oral administration.
Duration of ActionThe glucose-lowering effect lasts for approximately 24 hours, allowing once-daily dosing.

How It Works

This medicine works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the proximal tubules of the kidneys. This transporter is responsible for reabsorbing most of the glucose filtered by the kidneys. By blocking SGLT2, this medicine reduces glucose reabsorption, leading to increased urinary glucose excretion. This effect lowers blood glucose levels independently of insulin secretion. Additionally, the loss of glucose in urine leads to mild diuresis and natriuresis, which can contribute to reductions in blood pressure and body weight. The exact mechanisms by which this medicine reduces cardiovascular and heart failure risks are not fully understood but may involve improvements in cardiac metabolism and reduced arterial stiffness.

Mechanism Steps

1
Inhibition of SGLT2: This medicine binds to and inhibits the SGLT2 protein in the proximal renal tubules.
2
Reduced Glucose Reabsorption: Inhibition of SGLT2 prevents the reabsorption of filtered glucose back into the bloodstream.
3
Increased Urinary Glucose Excretion: As a result, excess glucose is excreted in the urine, lowering blood glucose levels.
4
Osmotic Diuresis: The presence of glucose in the urine draws water into the urine, causing increased urination and mild dehydration.
5
Cardiovascular and Renal Benefits: The combined effects lead to reduced blood pressure, weight loss, and improved cardiovascular and renal outcomes.

💡 How to Take jardiance 10mg tablet

Strength: 10 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it at the same time each day, preferably in the morning.
4You can take it with or without food.
5Do not crush, chew, or break the tablet.
6Stay well hydrated throughout the day.

Dosage Information

Adult DosageThe recommended dose of this medicine is 10 mg once daily in the morning, with or without food. The dose may be increased to 25 mg once daily if additional glycemic control is needed and the patient tolerates the 10 mg dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo dose adjustment is recommended based on age alone. However, elderly patients may be more susceptible to dehydration and renal impairment. Monitor renal function and hydration status closely.
Renal ImpairmentFor patients with eGFR 30-60 mL/min/1.73 m2, dose adjustment may be needed. This medicine is not recommended for patients with eGFR <30 mL/min/1.73 m2. Consult a nephrologist for individualized dosing.
Hepatic ImpairmentNo dose adjustment is recommended for patients with mild to moderate hepatic impairment. Use is not recommended in severe hepatic impairment.
Maximum Daily Dose25 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase drug levels and risk of side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of jardiance 10mg tablet

✅ Common Side Effects

Urinary tract infection (Common (5-10%))
Stay hydrated and maintain good hygiene. Consult doctor if symptoms persist.
Genital fungal infection (Common (5-10%))
Keep genital area clean and dry. Consult doctor for antifungal treatment if needed.
Increased urination (Common (5-10%))
Stay well hydrated. This usually resolves with continued use.
Nausea (Uncommon (1-5%))
Take with food to reduce nausea. Consult doctor if persistent.
Thirst (Common (5-10%))
Drink plenty of water throughout the day.

🚨 Serious Side Effects

Ketoacidosis (Rare (<0.1%))
Seek immediate medical attention if you experience nausea, vomiting, abdominal pain, confusion, or fruity-smelling breath.
Severe urinary tract infection (Rare (<0.1%))
Seek immediate medical attention if you have fever, chills, or pain in the lower back or side.
Necrotizing fasciitis of the perineum (Very rare (<0.01%))
Seek immediate medical attention if you experience severe pain, redness, or swelling in the genital area, along with fever and malaise.
Dehydration and hypotension (Uncommon (1-5%))
Stay hydrated. Seek medical attention if you feel dizzy, lightheaded, or have a rapid heartbeat.

⚠️ Rare Side Effects

Bone fractures
Report any unusual bone pain or fractures to your doctor.
Lower limb amputation
Report any pain, numbness, or discoloration in the legs or feet to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Diuretics Major
Insulin Major
Lithium Moderate
ACE inhibitors Moderate
NSAIDs Minor

🚨 Major Interactions

  • Diuretics
  • Insulin or insulin secretagogues

⚡ Moderate Interactions

  • Lithium
  • ACE inhibitors

🍷 Alcohol Interaction

Alcohol may increase the risk of ketoacidosis and dehydration. It is advisable to limit or avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to empagliflozin or any component of the formulation","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Risk of ketoacidosis, which can occur even with normal blood glucose levels.","Increased risk of urinary tract and genital infections.","May cause dehydration and hypotension; monitor volume status.","Not recommended for patients with severe hepatic impairment.","May increase risk of bone fractures and amputations.","Use with caution in elderly patients and those with renal impairment."]

🤱 Lactation Safety

Not recommended during breastfeeding. It is not known if this medicine is excreted in human milk. Consult your doctor before breastfeeding.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have kidney or liver disease, are on a low-salt diet, or have a history of urinary tract infections. Stay well hydrated to prevent dehydration. Maintain good genital hygiene to reduce the risk of infections. Do not start or stop this medicine without consulting your doctor. If you experience symptoms of ketoacidosis such as nausea, vomiting, abdominal pain, confusion, or fruity-smelling breath, seek immediate medical attention. Avoid excessive alcohol consumption as it may increase the risk of ketoacidosis. This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you. Regular monitoring of blood sugar, kidney function, and ketones may be required.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to dehydration, hypotension, and renal impairment. Monitor renal function and hydration status closely. Dose adjustment may be needed based on kidney function.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to the risk of ketoacidosis. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. Maintain good oral hygiene. No specific precautions are required, but monitor for any signs of infection.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve insulin sensitivity.
🥗
Engage in regular physical activity, such as walking or swimming.
😴
Follow a balanced diet rich in fiber and low in processed sugars.
💧
Stay well hydrated by drinking plenty of water.
🧘
Monitor your blood sugar levels regularly.
🌞
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

Exercise is encouraged, but stay hydrated to prevent dehydration. Avoid strenuous activities in hot weather. If you experience dizziness or weakness, stop and consult your doctor.

🥗 Diet Recommendations

Include plenty of vegetables and whole grains.
Limit intake of sugary drinks and processed foods.
Choose lean proteins and healthy fats.
Stay hydrated with water throughout the day.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or increased urination, which could affect work and daily activities. Avoid driving or operating machinery until you know how it affects you. Take it in the morning to minimize nighttime urination.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your doctor advises discontinuation, follow their instructions. Stopping abruptly may lead to uncontrolled blood sugar levels.

📅 Long-Term Use Effects

Long-term use may lead to sustained improvements in blood sugar control and cardiovascular health. Regular monitoring of kidney function, blood pressure, and signs of infections is necessary. Some patients may experience persistent genital fungal infections or urinary tract infections. The risk of bone fractures and amputations should be monitored.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Diet and exercise

Lifestyle modifications can help manage type 2 diabetes and complement medicine.

Evidence: Well-established
Other oral antidiabetics

Metformin, sulfonylureas, or DPP-4 inhibitors may be alternatives based on individual needs.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, maintain routine vaccinations as advised by your doctor, especially for influenza and pneumonia.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor for dose timing adjustments. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with type 2 diabetes and a history of heart disease
Started this medicine as prescribed by his doctor. Within a few weeks, his blood sugar levels improved, and he felt more energetic. He was advised to stay hydrated and maintain good hygiene. He experienced mild increased urination initially, which subsided over time.
💡 Lesson: Consistent use and lifestyle modifications can lead to better diabetes control and reduced cardiovascular risk.
👤 A 62-year-old woman with type 2 diabetes and obesity
Was prescribed this medicine to improve blood sugar control. She noticed a gradual weight loss of about 2 kg over three months. She also reported fewer episodes of high blood sugar. She was advised to monitor her kidney function regularly.
💡 Lesson: This medicine can aid in modest weight loss and improve glycemic control when combined with diet and exercise.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood glucose within 1-2 hours, but full effects may take a few weeks.

Q: Can I take this medicine if I have kidney disease?

A: It depends on the severity of kidney disease. Consult your doctor; it may not be recommended if eGFR is below 30.

Q: Does this medicine cause weight loss?

A: It may cause modest weight loss due to caloric loss through urine.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for jardiance 10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for type 1 diabetes.
    Fact: This medicine is not approved for type 1 diabetes and may increase the risk of ketoacidosis.
  • Myth: This medicine causes weight gain.
    Fact: This medicine may actually promote modest weight loss due to caloric loss through urine.
  • Myth: This medicine can be taken without any monitoring.
    Fact: Regular monitoring of blood sugar, kidney function, and ketones is essential.

🔄 Alternative Options

Generic Alternatives

  • Empagliflozin 10 mg tablet

Brand Alternatives

  • Jardiance 10 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Empagliflozin","class":"SGLT2 inhibitor","primary_use":"Type 2 diabetes, cardiovascular risk reduction","dosing":"10-25 mg once daily"},{"medicine":"Dapagliflozin","class":"SGLT2 inhibitor","primary_use":"Type 2 diabetes, heart failure","dosing":"5-10 mg once daily"},{"medicine":"Canagliflozin","class":"SGLT2 inhibitor","primary_use":"Type 2 diabetes","dosing":"100-300 mg once daily"}]

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