Januric SR 250 Tablet (Allopurinol 250 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe skin rash, blistering, or peeling skin
- Yellowing of skin or eyes (jaundice)
- Dark urine or decreased urine output
- Unusual bleeding or bruising
- Severe abdominal pain or persistent vomiting
- Fever with sore throat or mouth ulcers
- Swelling of face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is januric sr 250 tablet used for?
This medicine contains allopurinol 250 mg, used to lower uric acid levels and prevent gout attacks and uric acid kidney stones. It works by inhibiting xanthine oxidase. It is not a painkiller and should not be used during an acute gout attack. Take it exactly as prescribed by your doctor.
- Generic Name: Allopurinol (250mg)
- Manufacturer: ADN Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 januric sr 250 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एलोप्यूरिनॉल 250 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग गाउट (गठिया) के दौरे को रोकने और यूरिक एसिड के स्तर को कम करने के लिए किया जाता है। यह यूरिक एसिड के कारण होने वाली गुर्दे की पथरी को रोकने में भी मदद करती है। यह दवा दर्द निवारक नहीं है और गाउट के तीव्र दौरे में राहत नहीं देती। इसे डॉक्टर की सलाह पर ही शुरू करें और नियमित रूप से लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द और नींद आना शामिल हैं। कभी-कभी त्वचा पर चकत्ते भी हो सकते हैं, जिन्हें तुरंत डॉक्टर को बताना चाहिए। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें तीव्र एलर्जी, लीवर की सूजन, गुर्दे की समस्या और रक्त कोशिकाओं की कमी शामिल हो सकती है। यदि आपको त्वचा पर गंभीर दाने, पीलिया, या असामान्य रक्तस्राव दिखे तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पर्याप्त पानी पिएं। शराब से बचें। अन्य दवाओं के साथ इसके परस्पर प्रभाव के बारे में डॉक्टर को बताएं। त्वचा पर चकत्ते दिखने पर दवा बंद करें और डॉक्टर से संपर्क करें। नियमित रूप से यूरिक एसिड, गुर्दे और लीवर की जांच कराएं। गाउट के तीव्र दौरे में इस दवा का उपयोग न करें।
💊 januric sr 250 tablet Uses & Benefits
[{"condition":"Gout","description":"Prevents recurrent gout attacks by lowering uric acid levels in the blood.","evidence":"Well-established"},{"condition":"Uric acid kidney stones","description":"Helps prevent the formation of uric acid stones in the kidneys.","evidence":"Well-established"},{"condition":"Hyperuricemia associated with chemotherapy","description":"Used to prevent and treat high uric acid levels that can occur when cancer cells break down rapidly during chemotherapy.","evidence":"Well-established"},{"condition":"Tumor lysis syndrome","description":"Used in the prevention and management of tumor lysis syndrome in patients with certain cancers.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Angina pectoris","description":"Sometimes studied for reducing angina episodes, but not routinely recommended.","evidence":"Limited"},{"condition":"Inflammatory bowel disease","description":"Occasionally used off-label, but evidence is insufficient.","evidence":"Limited"}]
Primary treatment for: Gout
Also treats: Uric acid kidney stones, Hyperuricemia, Tumor lysis syndrome
📋 Drug Information
| Generic Name(s) | Allopurinol (250mg) |
| Brand Name | januric sr 250 tablet |
| Manufacturer | ADN Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Xanthine oxidase Inhibitors-gout |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container, tightly closed. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as stated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the enzyme xanthine oxidase. Xanthine oxidase is responsible for converting hypoxanthine to xanthine and then to uric acid. By blocking this enzyme, allopurinol reduces the production of uric acid in the body. Lower uric acid levels help prevent the formation of uric acid crystals in joints and kidneys, which are responsible for gout attacks and kidney stones. This medicine does not relieve pain or inflammation during an acute gout attack; it is used to prevent future attacks by maintaining low uric acid levels.
Mechanism Steps
💡 How to Take januric sr 250 tablet
Strength: Tablet, 250 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for gout is 100 mg to 300 mg per day, depending on the severity of the condition and kidney function. For prevention of uric acid stones, the dose may be lower. For hyperuricemia associated with chemotherapy, higher doses may be used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require lower doses. Dose should be individualized by a qualified clinician based on renal function. Regular monitoring is advised. |
| Renal Impairment | In patients with kidney disease, the dose of this medicine should be reduced based on creatinine clearance. The dose must be individualized by a qualified clinician. Regular monitoring of kidney function is essential. |
| Hepatic Impairment | In patients with liver disease, this medicine should be used with caution. Dose adjustment may be necessary. Regular monitoring of liver function is advised. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 800 mg, but doses above 300 mg are rarely used. The dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of januric sr 250 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Azathioprine | Major | |
| Mercaptopurine | Major | |
| Warfarin | Major | |
| Thiazide diuretics | Moderate | |
| Ampicillin | Moderate | |
| ACE inhibitors | Moderate | |
| Antacids | Minor | |
| Oral iron | Minor |
🚨 Major Interactions
- Azathioprine
- Mercaptopurine
- Warfarin
⚡ Moderate Interactions
- Thiazide diuretics
- Ampicillin
- ACE inhibitors
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase uric acid levels and may reduce the effectiveness of allopurinol. It can also increase the risk of liver problems. It is best to discuss alcohol use with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or severe allergic reaction to allopurinol","Severe liver disease","Severe kidney disease (dose adjustment may be needed)","Acute gout attack (treatment should be initiated after the attack resolves)"]
⚠️ Warnings & Precautions
["This medicine may cause serious skin reactions. Stop the medicine and seek immediate medical attention if you develop a rash or other signs of allergic reaction.","This medicine can increase the risk of gout attacks during the first few weeks of treatment. Your doctor may prescribe another medicine to prevent this.","Regular blood tests are needed to monitor uric acid levels, kidney function, and liver function.","Avoid alcohol while taking this medicine.","Inform your doctor if you have kidney or liver disease, as dose adjustments may be necessary.","This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Do not take this medicine to treat an acute gout attack; it is for prevention."]
🤱 Lactation Safety
Allopurinol is excreted in breast milk. It is not recommended for use during breastfeeding unless advised by a doctor. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhea, dizziness, and abdominal pain. In severe cases, it may lead to liver or kidney damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Contact a poison control center or emergency services right away.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not start or stop this medicine without medical advice. Drink plenty of fluids, especially water, to help prevent kidney stones. Avoid alcohol, as it can increase uric acid levels and reduce the effectiveness of this medicine. Inform your doctor about all other medicines you are taking, especially azathioprine, mercaptopurine, warfarin, and diuretics, as interactions can occur. If you develop a skin rash, stop the medicine and contact your doctor immediately. Regular blood tests to check uric acid, kidney function, and liver function are important. Do not take this medicine to treat an acute gout attack; it is for prevention. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may require lower doses. Regular monitoring of kidney function is important. They may also be more susceptible to side effects such as drowsiness and skin rash.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Allopurinol is not recommended during pregnancy unless clearly needed. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with other medications used during surgery. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific contraindications, but it is important for your dentist to know your complete medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine. However, if you experience joint pain or swelling during an acute gout attack, rest the affected joint and avoid strenuous activity. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not significantly impact your daily activities. Continue your normal routine unless advised otherwise by your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Stopping suddenly can lead to a gout flare. Your doctor may adjust or stop the medicine based on your uric acid levels, kidney function, and overall health. If you experience a serious side effect, stop the medicine and seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for preventing gout attacks and kidney stones. Regular monitoring of uric acid levels, kidney function, and liver function is recommended. Rarely, long-term use may be associated with cataracts or peripheral neuropathy. Do not stop the medicine without consulting your doctor, as stopping suddenly can lead to a gout flare.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Limiting purine-rich foods and alcohol can help lower uric acid levels.
Evidence: Well-establishedLosing excess weight can reduce uric acid levels and gout attacks.
Evidence: Well-establishedFebuxostat or probenecid may be alternatives if allopurinol is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Declare the medicine at customs if required. Keep enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It may take several weeks to months to achieve the full uric acid-lowering effect and reduce gout attacks.
A: No, this medicine is not for treating an acute gout attack. It is used to prevent future attacks. Your doctor may prescribe other medicines for acute pain.
A: Avoid alcohol and high-purine foods. Also, inform your doctor about all other medicines you take.
A: Yes, taking it with food can reduce stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for januric sr 250 tablet
View AllAlternative brands with exact same active ingredient:
-
zyprinol 250 mg tabletZydus Cadila ₹25.00 79.2% CHEAPER
-
lodiric-sr 250mg capsuleNovartis India Ltd ₹66.94 44.2% CHEAPER
-
logout 250mg capsule srInga Laboratories Pvt Ltd ₹107.25 10.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken to relieve an acute gout attack.
Fact: This medicine is not a painkiller and does not relieve acute gout pain. It is used to prevent future attacks. - Myth: Once uric acid levels are normal, this medicine can be stopped.
Fact: This medicine is usually continued long-term to maintain normal uric acid levels and prevent attacks. Do not stop without medical advice. - Myth: This medicine has no side effects.
Fact: Like all medicines, this medicine can cause side effects, including rash, nausea, and rarely serious allergic reactions.
🔄 Alternative Options
Generic Alternatives
- Allopurinol 250 mg tablet
Brand Alternatives
- Januric SR 250 Tablet