ivrea shampoo - Ivermectin (0.5% w/v) medicine

Ivermectin 0.5% w/v Shampoo: Complete Guide

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🏭 Ajanta Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for head lice treatment.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
  • Signs of severe skin reaction: blistering, peeling, or extensive redness.
  • Eye contact: if shampoo gets into eyes, rinse thoroughly and seek medical advice if irritation persists.
  • Accidental ingestion: seek immediate medical attention.
  • No improvement after treatment: if live lice are still present after the recommended treatment period, consult a doctor.

If experiencing severe symptoms, call emergency services immediately.

What is ivrea shampoo used for?

This medicine is a topical shampoo containing ivermectin 0.5% w/v, used to treat head lice infestation. It works by paralyzing and killing the lice. Apply to dry hair, leave for 10 minutes, and rinse thoroughly.

  • Generic Name: Ivermectin (0.5% w/v)
  • Manufacturer: Ajanta Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ivrea shampoo के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल शैम्पू है जिसमें आइवरमेक्टिन 0.5% w/v होता है। इसका उपयोग सिर की जूँ (हेड लाइस) के इलाज के लिए किया जाता है। यह जूँ को पक्षाघात करके मार देती है। इसे सूखे बालों और सिर की त्वचा पर लगाएं, 10 मिनट तक छोड़ें और फिर अच्छी तरह धो लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिर की त्वचा में जलन, खुजली, लालिमा या जलन शामिल हो सकती है। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। दुर्लभ मामलों में एलर्जी की प्रतिक्रिया हो सकती है जैसे चकत्ते, सूजन या सांस लेने में कठिनाई। ऐसे में तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: केवल बाहरी उपयोग के लिए। आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। टूटी या जली हुई त्वचा पर न लगाएं। उपयोग के बाद हाथ धो लें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं या किसी भी दवा से एलर्जी है तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 ivrea shampoo Uses & Benefits

  • [{"condition":"Head lice infestation","description":"This medicine is used to treat infestations of head lice (Pediculus humanus capitis) on the scalp and hair.
  • It works by paralyzing and killing the lice.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Scabies","description":"Topical ivermectin has been studied for scabies, but this shampoo formulation is not specifically approved for that use.","evidence":"Limited"}]

Primary treatment for: Head lice infestation

📋 Drug Information

Generic Name(s)Ivermectin (0.5% w/v)
Brand Nameivrea shampoo
ManufacturerAjanta Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassEctoparasiticides
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine to dry hair and scalp, not wet, for maximum effectiveness.
2
Leave the shampoo on for the full 10 minutes as directed; do not rinse early.
3
Use a fine-toothed comb to remove dead lice and nits after rinsing.
4
Repeat treatment after 9-10 days if live lice are still present, as advised by your doctor.
5
Avoid using conditioner or other hair products before applying this medicine, as they may reduce its efficacy.
6
Wash all clothing, bedding, and hats used by the infected person in hot water to prevent reinfestation.
7
Check all family members for lice and treat them if necessary to prevent spread.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy scalp
This medicine is commonly prescribed for head lice which causes itching.
Likely Use
✅
Visible lice or nits in hair
This medicine is used to treat head lice infestation.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of ivermectin following topical application to the scalp is minimal. Not established from the available information for this specific formulation.
DistributionNot established from the available information for this specific topical formulation.
Protein BindingNot established from the available information for this specific topical formulation.
MetabolismNot established from the available information for this specific topical formulation.
Half-LifeNot established from the available information for this specific topical formulation.
ExcretionNot established from the available information for this specific topical formulation.
BioavailabilityNot established from the available information for this specific topical formulation.
Onset of ActionThe onset of action for lice eradication is typically within 24 to 48 hours after application, but complete elimination may require reapplication as directed.
Peak Plasma TimeNot established from the available information for this specific topical formulation.
Duration of ActionThe effect on lice is immediate, but the medicine may remain active on the scalp for several hours after application.

How It Works

Ivermectin binds to glutamate-gated chloride channels and gamma-aminobutyric acid (GABA) receptors in the nerve and muscle cells of parasites. This binding increases the permeability of the cell membrane to chloride ions, leading to hyperpolarization and subsequent paralysis and death of the parasite. In arthropods such as lice, this results in their elimination from the host.

Mechanism Steps

1
Binding to parasite ion channels: Ivermectin binds selectively to glutamate-gated chloride channels and GABA receptors in the nerve and muscle cells of lice.
2
Increased chloride ion permeability: This binding causes an influx of chloride ions into the cells, leading to hyperpolarization.
3
Paralysis and death of the parasite: The hyperpolarization results in paralysis of the parasite's muscles and nerves, ultimately causing its death.

💡 How to Take ivrea shampoo

Strength: Ivermectin 0.5% w/v shampoo

1Wash your hands before and after application.
2Apply the shampoo to dry hair and scalp.
3Massage gently to lather.
4Leave on for 10 minutes.
5Rinse thoroughly with warm water.
6Comb hair with a fine-toothed comb to remove dead lice and nits.
7Do not use more often than prescribed.

Dosage Information

Adult DosageThe usual adult dose for head lice is to apply the shampoo to dry hair and scalp, lather, and leave on for 10 minutes, then rinse thoroughly. This is typically a single application. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Follow your doctor's instructions exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. Safety and efficacy in children under 6 months have not been established.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, consult a doctor before use.
Renal ImpairmentNo dosage adjustment is required for renal impairment as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustment is required for hepatic impairment as systemic absorption is minimal.
Maximum Daily DoseNot applicable for topical use. Use as directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled application
→ Apply as soon as you remember.
💡 If it is almost time for the next application, skip the missed one and continue with your regular schedule.
📌 If you miss the follow-up application after 9-10 days
→ Apply as soon as you remember, but do not exceed the recommended frequency.
💡 Consult your doctor if unsure.

⚠️ Side Effects of ivrea shampoo

✅ Common Side Effects

Scalp irritation (Common (1-10%))
Usually resolves on its own. If persistent, consult a doctor.
Itching (Common (1-10%))
May be due to lice or irritation. Consult if severe.
Redness (Common (1-10%))
Usually temporary. Avoid scratching.
Burning sensation (Common (1-10%))
Rinse with cool water if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Severe skin reaction (Rare (<0.1%))
Discontinue use and consult a doctor if you develop blistering, peeling, or severe redness.

⚠️ Rare Side Effects

Hair loss
Consult a doctor if significant hair loss occurs.
Eye irritation if contact occurs
Rinse eyes thoroughly with water and consult a doctor if irritation persists.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ivermectin or any component of the formulation","Application to broken or irritated skin","Use in children under 6 months of age without medical advice"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes. If contact occurs, rinse thoroughly with water.","Do not apply to areas of the skin that are broken, inflamed, or infected.","Wash hands after application.","Do not use if you are allergic to ivermectin.","Consult a doctor if condition persists or worsens after treatment.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether ivermectin applied topically is excreted in breast milk. Consult a doctor before use if breastfeeding.

💊 Overdose Management

Overdose with this topical medicine is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of ivermectin overdose may include nausea, vomiting, diarrhea, abdominal pain, dizziness, and in severe cases, seizures, coma, and respiratory failure. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or inflamed skin. Wash hands thoroughly after application. Do not use this medicine if you are allergic to ivermectin or any of its ingredients. Consult a doctor before use if you are pregnant, planning to become pregnant, or breastfeeding. Keep out of reach of children. Do not exceed the recommended dose or frequency of application. If symptoms persist after the recommended treatment period, seek medical advice. Do not use on children under the age of 6 months unless directed by a physician. Avoid using other topical products on the scalp concurrently unless advised by a doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients can use this medicine safely. However, they may have thinner or more sensitive skin, so monitor for irritation. Consult a doctor if you have any concerns.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of topical ivermectin during pregnancy has not been fully established, and alternative treatments may be preferred.

🏥 Post-Surgery Considerations

No specific precautions are required after surgery. However, if you have had recent scalp surgery, consult your doctor before applying this medicine to avoid irritation.

🦷 Dental Procedures

No specific considerations for dental procedures. This medicine is applied to the scalp and does not affect dental health.

💚 Lifestyle Tips for Better Results

🏃
Avoid sharing combs, brushes, hats, or pillows with others to prevent spread.
🥗
Wash bedding, clothing, and towels in hot water (at least 54°C) and dry on high heat.
😴
Vacuum carpets and furniture to remove any fallen hairs with nits.
💧
Soak combs and brushes in hot water for 10 minutes.
🧘
Check all family members for lice and treat if necessary.
🌞
Avoid close head-to-head contact with others until infestation is cleared.

🏋️ Exercise Considerations

No specific exercise precautions are needed while using this medicine. However, avoid swimming or activities that cause excessive sweating immediately after application to ensure the medicine remains on the scalp for the required duration.

🥗 Diet Recommendations

Maintain a balanced diet to support overall health and immune function.
Stay hydrated to keep skin and scalp healthy.
Include foods rich in vitamins and minerals, such as fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine has minimal impact on daily activities. You can resume normal activities immediately after application and rinsing. However, avoid close contact with others until the infestation is treated to prevent spread.

🛑 When to Stop This Medicine

Stop using this medicine after the recommended treatment course unless directed otherwise by your doctor. If you experience severe side effects or allergic reactions, discontinue use and seek medical attention immediately. Do not stop without consulting your doctor if you are in the middle of treatment.

📅 Long-Term Use Effects

Long-term effects of topical ivermectin are not well established as it is typically used for short durations. Repeated use may lead to skin irritation or allergic reactions. If you need to use this medicine frequently, consult a doctor to determine the underlying cause and alternative treatments.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Wet combing

Regular combing with a fine-toothed comb can help remove lice and nits, especially in mild infestations.

Evidence: Well-established
Permethrin 1% shampoo

Another topical treatment for head lice, often used as first-line therapy.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions between this medicine and vaccines. You can receive vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store at room temperature and protect from extreme heat or cold. If you are traveling across time zones, no adjustments are needed as it is used as a single application. Keep it in your carry-on luggage if possible.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old mother noticed her child scratching her head constantly.
She checked and found live lice. She consulted a doctor who prescribed this medicine. She applied it to her child's dry hair, left it for 10 minutes, and rinsed. She also combed out nits. The itching stopped within a day, and a follow-up application after 10 days ensured no lice remained.
💡 Lesson: Proper application and follow-up treatment are key to eliminating head lice.
👤 A 45-year-old teacher had recurrent head lice despite using over-the-counter products.
She was prescribed this medicine. She applied it as directed and also treated her family members. She washed all bedding and clothing in hot water. The infestation cleared completely.
💡 Lesson: Treating all close contacts and cleaning the environment helps prevent reinfestation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts killing lice immediately upon application. However, you may still see dead lice or nits after rinsing. A follow-up treatment after 9-10 days is often recommended to kill any newly hatched lice.

Q: Can I use this medicine if I am pregnant?

A: Consult your doctor before using this medicine if you are pregnant or planning to become pregnant. The safety of topical ivermectin during pregnancy has not been fully established.

Q: Is it safe for children?

A: This medicine should not be used in children under 6 months of age without medical advice. For older children, consult a pediatrician for proper guidance.

Q: What should I do if I get it in my eyes?

A: Rinse your eyes thoroughly with water immediately. If irritation persists, seek medical attention.

Q: Can I use a hair dryer after applying?

A: No, do not use a hair dryer or other heat sources on your hair while the medicine is applied, as it may reduce effectiveness or cause irritation.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my child?
  • How long does it take to work?
  • What if I miss a dose?
  • Can I use it during pregnancy?
  • Does it cause hair loss?
  • Can I use it with other hair products?

🔄 Substitutes for ivrea shampoo

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Ivermectin shampoo can be used to prevent lice.
    Fact: This medicine is not for prevention. It should only be used when an active infestation is confirmed.
  • Myth: Ivermectin shampoo is safe to ingest.
    Fact: This product is for external use only. Ingestion can be dangerous and requires immediate medical attention.

📊 Comparison with Similar Medicines

[{"medicine":"Ivermectin 0.5% shampoo","class":"Avermectin","route":"Topical","primary_use":"Head lice"},{"medicine":"Permethrin 1% shampoo","class":"Pyrethroid","route":"Topical","primary_use":"Head lice"}]

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