Inapure ER 10 Tablet (Ivabradine 10mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fainting or severe dizziness
- Heart rate below 50 beats per minute
- Chest pain that is new or worsening
- Shortness of breath or sudden weight gain
- Swelling of face, lips, or throat
- Irregular heartbeat or palpitations
- Yellowing of skin or eyes (jaundice)
If experiencing severe symptoms, call emergency services immediately.
What is ivables od 10mg tablet used for?
This medicine is a prescription heart medicine that slows the heart rate to treat stable angina and certain types of heart failure. It works by blocking the funny current in the heart's pacemaker. It is taken twice daily and should not be stopped without medical advice.
- Generic Name: Ivabradine (10mg)
- Manufacturer: Lloyd Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ivables od 10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा इवाब्राडीन 10 मिलीग्राम की एक प्रिस्क्रिप्शन टैबलेट है, जिसका उपयोग स्थिर एनजाइना (दिल की धमनियों में रक्त के प्रवाह में कमी के कारण सीने में दर्द) और कुछ प्रकार के दिल की विफलता के इलाज के लिए किया जाता है। यह दिल की धड़कन को धीमा करके दिल पर दबाव कम करती है और ऑक्सीजन की मांग को कम करती है। यह बीटा-ब्लॉकर दवाओं को सहन न कर पाने वाले मरीजों के लिए एक विकल्प है। इसे डॉक्टर के निर्देशानुसार ही लें और बिना सलाह के बंद न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में दृष्टि में अस्थायी चमक (फॉस्फीन), धुंधली दृष्टि, सिरदर्द, चक्कर आना और दिल की धड़कन धीमी होना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अत्यधिक धीमी हृदय गति, हृदय रुकावट, या एलर्जी प्रतिक्रिया हो सकती है। यदि आपको बेहोशी, गंभीर सीने में दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। टैबलेट को चबाएं या तोड़ें नहीं, पूरा निगल लें। इस दवा के साथ अंगूर का जूस या अंगूर न खाएं, क्योंकि इससे दवा का स्तर बढ़ सकता है और दुष्प्रभावों का खतरा हो सकता है। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। दिल की धड़कन और रक्तचाप की नियमित निगरानी करें। गर्भवती महिलाओं को इस दवा से बचना चाहिए।
💊 ivables od 10mg tablet Uses & Benefits
[{"condition":"Stable angina pectoris","description":"Used to reduce the frequency of angina attacks in patients with chronic stable angina who have a contraindication or intolerance to beta-blockers, or in combination with beta-blockers when optimal control is not achieved.","evidence":"Well-established"},{"condition":"Chronic heart failure with reduced ejection fraction","description":"Used in combination with standard therapy to reduce the risk of hospitalization for worsening heart failure in patients with systolic dysfunction and heart rate ≥70 beats per minute.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Inappropriate sinus tachycardia","description":"Sometimes prescribed off-label to control elevated heart rate in patients with inappropriate sinus tachycardia when other treatments fail.","evidence":"Limited"}]
Primary treatment for: Stable angina pectoris and chronic heart failure with reduced ejection fraction.
Also treats: Inappropriate sinus tachycardia (off-label), Coronary artery disease
📋 Drug Information
| Generic Name(s) | Ivabradine (10mg) |
| Brand Name | ivables od 10mg tablet |
| Manufacturer | Lloyd Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | I F sodium channel (sinoatrial node) current blockers |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, tightly closed, away from moisture and direct sunlight. Do not refrigerate or freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine selectively inhibits the funny current (If) in the sinoatrial node of the heart. The funny current is a mixed sodium-potassium inward current that helps generate the spontaneous diastolic depolarization responsible for setting the heart's natural pace. By blocking this current, ivabradine slows the rate of diastolic depolarization, thereby reducing the heart rate. This effect is specific to the sinoatrial node and does not affect other cardiac tissues or blood vessels, leading to a pure heart-rate-lowering effect without negative inotropy or hypotension.
Mechanism Steps
💡 How to Take ivables od 10mg tablet
Strength: Ivabradine 10 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual starting dose for stable angina is 5 mg twice daily, which may be increased to 7.5 mg twice daily after 3-4 weeks based on heart rate and symptoms. For chronic heart failure, the starting dose is 5 mg twice daily, with adjustments based on heart rate and tolerability. The maximum dose is 7.5 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but they may be more sensitive to the heart rate-lowering effects. Monitor heart rate closely and adjust dose as needed. |
| Renal Impairment | No dose adjustment is required for mild to moderate renal impairment. In severe renal impairment (creatinine clearance <15 mL/min), use with caution as safety and efficacy have not been established. |
| Hepatic Impairment | In mild hepatic impairment, no dose adjustment is needed. In moderate hepatic impairment (Child-Pugh B), the starting dose should be reduced to 2.5 mg twice daily and titrated carefully. In severe hepatic impairment (Child-Pugh C), the medicine is contraindicated. |
| Maximum Daily Dose | 15 mg per day (7.5 mg twice daily). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ivables od 10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Diltiazem | Moderate | |
| Verapamil | Moderate | |
| Rifampicin | Major | |
| Beta-blockers | Moderate | |
| Grapefruit juice | Moderate | |
| St. John's wort | Moderate | |
| Clarithromycin | Major | |
| Ritonavir | Major | |
| Spironolactone | Moderate |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir)
- Moderate CYP3A4 inhibitors (e.g., diltiazem, verapamil, grapefruit juice)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St. John's wort)
⚡ Moderate Interactions
- Beta-blockers
- Calcium channel blockers (e.g., diltiazem, verapamil)
- Potassium-sparing diuretics (e.g., spironolactone)
🍷 Alcohol Interaction
Alcohol may increase the heart rate-lowering effect of this medicine and can worsen dizziness or lightheadedness. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia (heart rate
⚠️ Warnings & Precautions
["This medicine should only be prescribed by a cardiologist or a physician experienced in treating heart failure or angina.","Do not use this medicine to treat acute angina attacks; it is for chronic stable angina.","Monitor heart rate regularly; if resting heart rate falls below 50 bpm, dose reduction or discontinuation may be needed.","Use with caution in patients with mild to moderate hepatic impairment; dose adjustment may be required.","Avoid concomitant use with strong CYP3A4 inhibitors.","Use effective contraception in women of childbearing potential.","May cause visual disturbances; caution when driving or operating machinery.","Do not stop abruptly without medical advice."]
🤱 Lactation Safety
It is not known whether ivabradine is excreted in human breast milk. Because many medicines are excreted in breast milk, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose may cause severe bradycardia, hypotension, and other cardiac arrhythmias. There is no specific antidote. Treatment should be symptomatic and supportive, including close monitoring of heart rate and blood pressure. In case of severe bradycardia, atropine or temporary pacing may be required. Contact a poison control center or emergency services immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if less than half the dosing interval has passed. If more than half the interval has passed, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with water. Avoid grapefruit juice and grapefruit products while taking this medicine, as they can increase the levels of ivabradine in your blood and raise the risk of side effects. Inform your doctor about all other medicines you are taking, especially those for heart rhythm, blood pressure, or fungal infections. Do not stop taking this medicine suddenly without consulting your doctor. Regular monitoring of heart rate and blood pressure is important. Use effective contraception during treatment if you are a woman of childbearing potential, as this medicine may harm an unborn baby.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the heart rate-lowering effects of this medicine. Start with a lower dose and monitor heart rate closely. Falls due to dizziness or bradycardia are a concern; advise caution.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy unless clearly necessary. Women of childbearing potential should use effective contraception while taking this medicine. If you are planning pregnancy, consult your doctor to discuss alternative treatments.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may affect heart rate during surgery. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may interact with certain local anesthetics or medications used during dental procedures. No routine adjustment is usually needed, but your dentist may consult your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally encouraged, but avoid strenuous activities that cause chest pain or shortness of breath. Always warm up and cool down. If you experience dizziness, palpitations, or chest discomfort during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or visual disturbances, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most patients can continue their normal work activities with caution. Inform your employer if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects like fainting, severe bradycardia, or allergic reactions, seek immediate medical attention. Your doctor may adjust the dose or switch to another medicine if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. Regular monitoring of heart rate, blood pressure, and symptoms is necessary. In some patients, prolonged use may lead to visual disturbances or bradycardia. Periodic assessment of liver and kidney function is advised. Do not stop the medicine without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
First-line therapy for angina and heart failure; however, may not be suitable for patients with asthma or COPD.
Evidence: Well-establishedCan be used for angina but may have additional blood pressure-lowering effects.
Evidence: Well-establishedDiet, exercise, and stress management can complement medical therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, adjust dosing times gradually under medical guidance. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering heart rate within 1-2 hours, but full benefits for angina or heart failure may take several weeks.
A: No, do not stop without consulting your doctor. Stopping suddenly can worsen your condition.
A: If less than half the dosing interval has passed, take it as soon as you remember. If more, skip it and continue your regular schedule. Do not double dose.
A: Weight gain is not a common side effect. However, if you have heart failure, weight gain may indicate worsening condition and should be reported to your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for ivables od 10mg tablet
View AllAlternative brands with exact same active ingredient:
-
ivabrad 10mg tabletLupin Ltd ₹127.23 68.9% CHEAPER
-
ivapace 10mg tablet srCorona Remedies Pvt Ltd ₹187.50 54.2% CHEAPER
-
irban od 10 tablet prGlenmark Pharmaceuticals Ltd ₹250.00 38.9% CHEAPER
-
ivabeat 10mg tabletCipla Ltd ₹318.75 22.1% CHEAPER
-
coralan od 10mg tablet prServier India Private Limited ₹328.90 19.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of chest pain.
Fact: This medicine is specifically for stable angina and certain heart failure; it is not for acute angina attacks or other types of chest pain. - Myth: This medicine can be stopped once symptoms improve.
Fact: This medicine is usually a long-term treatment; stopping suddenly can worsen your condition. Always consult your doctor before stopping. - Myth: This medicine is safe to take with any other medicine.
Fact: This medicine interacts with many drugs, especially those affecting CYP3A4. Always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Ivabradine 10 mg tablet
Brand Alternatives
- Inapure ER 10 Tablet