Isordil 10 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not go away with rest or your fast-acting nitrate
- Fainting or severe dizziness
- Blurred vision or confusion
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing
- Very slow or irregular heartbeat
- Bluish discoloration of lips or skin
If experiencing severe symptoms, call emergency services immediately.
What is isordil 10 tablet used for?
This medicine is a nitrate used to prevent angina attacks and treat heart failure. It works by widening blood vessels to improve blood flow to the heart. It is not for immediate relief of an ongoing angina attack.
- Generic Name: Isosorbide Dinitrate (10mg)
- Manufacturer: Ipca Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 isordil 10 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना (सीने में दर्द) के दौरों को रोकने और दिल की विफलता के इलाज में उपयोग की जाती है। यह रक्त वाहिकाओं को फैलाकर दिल तक रक्त का प्रवाह बढ़ाती है और दिल पर दबाव कम करती है। यह दवा तीव्र एंजाइना के दौरे को तुरंत रोकने के लिए नहीं है। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर गर्मी लगना और धड़कन तेज होना शामिल हैं। सिरदर्द अक्सर शुरुआत में होता है और कुछ दिनों में ठीक हो जाता है। अगर आपको बहुत ज्यादा चक्कर आए, बेहोशी महसूस हो, या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब न पिएं क्योंकि इससे रक्तचाप बहुत कम हो सकता है। उठते समय धीरे-धीरे उठें ताकि चक्कर न आएं। एंजाइना के तीव्र दौरे के लिए इस दवा का उपयोग न करें। अपनी सभी दवाओं के बारे में डॉक्टर को बताएं, खासकर नपुंसकता की दवाओं के बारे में।
💊 isordil 10 tablet Uses & Benefits
[{"condition":"Prevention of angina pectoris","description":"This medicine is used regularly to reduce the frequency and severity of angina attacks in people with coronary artery disease.","evidence":"Well-established"},{"condition":"Heart failure","description":"This medicine is used as part of combination therapy to relieve symptoms and improve exercise tolerance in chronic heart failure.","evidence":"Well-established"},{"condition":"Hypertension in specific settings","description":"This medicine may be used in selected patients to help lower blood pressure, often in combination with other medicines.","evidence":"Moderate"},{"condition":"Esophageal spasm","description":"This medicine is sometimes used to relieve chest pain caused by esophageal spasm after other causes have been ruled out.","evidence":"Limited"}]
Off-label uses: [{"condition":"Raynaud's phenomenon","description":"This medicine is occasionally prescribed off-label to improve blood flow to the fingers and toes in people with Raynaud's phenomenon.","evidence":"Limited"},{"condition":"Anal fissure","description":"This medicine has been used off-label in some topical or oral forms to help heal anal fissures by improving blood flow.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Heart failure, Hypertension, Esophageal spasm
📋 Drug Information
| Generic Name(s) | Isosorbide Dinitrate (10mg) |
| Brand Name | isordil 10 tablet |
| Manufacturer | Ipca Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep in a dry place away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by releasing nitric oxide in the body. Nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic GMP levels in smooth muscle cells. Higher cyclic GMP causes the smooth muscle in blood vessels to relax, leading to vasodilation. This widening of veins and arteries reduces the heart's workload and improves blood supply to the heart muscle, which helps prevent angina.
Mechanism Steps
💡 How to Take isordil 10 tablet
Strength: Isosorbide Dinitrate 10 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 mg to 20 mg taken two to three times a day, depending on the condition being treated. For prevention of angina, the dose is often 10 mg to 20 mg taken two to three times daily. Your doctor may adjust the dose based on your response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for mild to moderate kidney disease. In severe kidney disease, use with caution and follow your doctor's advice. |
| Hepatic Impairment | Use with caution in patients with severe liver disease. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is generally 120 mg, but this must be determined by your doctor based on your condition. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of isordil 10 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Riociguat | Major | |
| Alcohol | Major | |
| Beta blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Other nitrates | Moderate | |
| Aspirin | Minor | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Sildenafil, tadalafil, vardenafil
- Riociguat
- Alcohol
⚡ Moderate Interactions
- Other blood pressure medicines
- Beta blockers
- Calcium channel blockers
🍷 Alcohol Interaction
Alcohol can increase the blood pressure lowering effect of this medicine and cause severe dizziness, fainting, or a drop in blood pressure. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to isosorbide dinitrate or other nitrates","Severe low blood pressure","Use of erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil","Use of riociguat","Severe anemia","Increased intracranial pressure","Constrictive pericarditis or cardiac tamponade"]
⚠️ Warnings & Precautions
["Do not use this medicine to treat an acute angina attack; use a fast-acting nitrate instead.","Avoid alcohol while taking this medicine.","Stand up slowly to prevent dizziness or fainting.","Tell your doctor if you have low blood pressure, heart failure, or liver or kidney disease.","Do not stop this medicine suddenly without talking to your doctor.","Use with caution in the elderly, who may be more sensitive to blood pressure lowering effects.","This medicine may cause headaches; do not increase the dose on your own to manage headaches."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe low blood pressure, headache, dizziness, fainting, and a fast heartbeat. If you suspect an overdose, seek emergency medical help immediately. Treatment is supportive and may include fluids, medicines to raise blood pressure, and monitoring in a hospital.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as your doctor prescribes, and do not change the dose without medical advice. Stand up slowly from sitting or lying positions to avoid dizziness. Avoid alcohol because it can make low blood pressure worse. Tell your doctor about all other medicines you take, especially those for erectile dysfunction, blood pressure, or heart conditions. Do not use this medicine to relieve an angina attack that is already in progress. Keep a fast-acting nitrate with you if your doctor has prescribed one for attacks. Store this medicine in its original container away from heat and moisture. If you become pregnant, plan to become pregnant, or are breastfeeding, talk to your doctor before continuing this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure lowering effects of this medicine. They may experience more dizziness and are at higher risk of falls. Start with a lower dose and monitor blood pressure regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before continuing this medicine. The safety of this medicine during pregnancy is not fully established, and your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with medicines used during surgery and affect blood pressure. Your doctor may advise you to stop it temporarily before surgery.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. It can cause low blood pressure, and your dentist may need to take precautions. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is good for your heart, but start slowly and avoid sudden strenuous activity. If you feel chest pain, dizziness, or shortness of breath during exercise, stop and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work activities with caution.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor may adjust or stop it based on your condition. If you experience severe side effects, contact your doctor immediately for advice.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, where the medicine becomes less effective. To prevent this, doctors often prescribe a nitrate-free interval each day. Regular monitoring of blood pressure and heart symptoms is important. Long-term use does not usually cause organ damage, but it should be reviewed periodically by your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress management can complement medicine for heart health.
Evidence: Well-establishedBeta blockers, calcium channel blockers, and other nitrates may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, people with heart disease should discuss vaccinations, such as flu and pneumonia vaccines, with their doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid extreme temperatures. If you are traveling across time zones, consult your doctor about adjusting your dosing schedule. Store it away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to work within 30 to 60 minutes after taking a dose, but it is not for immediate relief of an ongoing angina attack.
A: Yes, you can take it with or without food. However, take it the same way each time to keep absorption consistent.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop suddenly without talking to your doctor, as it can worsen your heart condition.
A: Use during pregnancy only if prescribed by your doctor. There is limited information about its safety in pregnant women.
🤔 Common Patient Concerns
🔄 Substitutes for isordil 10 tablet
View AllAlternative brands with exact same active ingredient:
-
anzidin 10mg tabletStadmed Pvt Ltd ₹6.34 90.9% CHEAPER
-
sosodil 10mg tabletAarux Pharmaceuticals Pvt Ltd ₹10.90 84.4% CHEAPER
-
cardicap 10mg tabletSun Pharmaceutical Industries Ltd ₹11.23 83.9% CHEAPER
-
monocard 10mg tabletZen Pharma Pvt Ltd ₹19.20 72.4% CHEAPER
-
vasodil 10mg tabletEast West Pharma ₹21.16 69.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken to stop an ongoing angina attack.
Fact: This medicine is for prevention. A fast-acting nitrate is used for immediate relief. - Myth: You can stop this medicine suddenly once you feel better.
Fact: Stopping suddenly can cause withdrawal and worsen angina. Always consult your doctor before stopping. - Myth: Taking this medicine with erectile dysfunction drugs is safe.
Fact: Combining them can cause severe low blood pressure and is dangerous.
🔄 Alternative Options
Generic Alternatives
- Isosorbide Dinitrate 10 mg tablet
Brand Alternatives
- Isordil 10 Tablet