ipacare 250mg injection - Cefepime (250mg) medicine

Abdopime 250mg Injection: Complete Medicine Guide

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🏭 H & Care Incorp 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe diarrhea with blood or mucus
  • Seizures or confusion
  • Decreased urine output or swelling in legs
  • Yellowing of skin or eyes
  • Severe rash or blistering

If experiencing severe symptoms, call emergency services immediately.

What is ipacare 250mg injection used for?

This medicine is a fourth-generation cephalosporin antibiotic used to treat severe bacterial infections. It is administered by injection in a hospital setting.

  • Generic Name: Cefepime (250mg)
  • Manufacturer: H & Care Incorp
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ipacare 250mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा एक शक्तिशाली एंटीबायोटिक है जिसका उपयोग गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह निमोनिया, मूत्र मार्ग संक्रमण, त्वचा संक्रमण और रक्त संक्रमण में प्रभावी है। यह अस्पताल में इंजेक्शन के रूप में दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, उल्टी, दाने और इंजेक्शन स्थल पर दर्द शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, दौरे और गुर्दे की समस्या हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल स्वास्थ्य पेशेवर द्वारा दी जानी चाहिए। अपनी सभी एलर्जी के बारे में डॉक्टर को बताएं। गुर्दे की बीमारी या दौरे की समस्या हो तो सावधानी बरतें। पूरा कोर्स पूरा करें। शराब से बचें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 ipacare 250mg injection Uses & Benefits

[{"condition":"Pneumonia","description":"Used to treat community-acquired and hospital-acquired pneumonia caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against complicated and uncomplicated urinary tract infections.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats infections such as cellulitis and abscesses caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Used as empiric therapy in cancer patients with fever and low white blood cell counts.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for complicated intra-abdominal infections.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Meningitis","description":"Sometimes used off-label for bacterial meningitis when other options are not suitable.","evidence":"Limited"},{"condition":"Endocarditis","description":"May be used off-label for certain cases of infective endocarditis.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Pneumonia, Urinary tract infections, Skin infections, Febrile neutropenia

📋 Drug Information

Generic Name(s)Cefepime (250mg)
Brand Nameipacare 250mg injection
ManufacturerH & Care Incorp
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 4th generation
Route of AdministrationParenteral (intravenous or intramuscular)
StorageStore at room temperature (20-25°C). Protect from light. Do not freeze. Reconstituted solutions should be used within the specified time as per the manufacturer's instructions.
Shelf LifeTypically 24 months from the date of manufacture. Refer to the product label for exact expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always verify renal function before prescribing this medicine, as dose adjustment is often required.
2
Monitor patients for signs of superinfection, especially with prolonged use.
3
Consider alternative antibiotics in patients with a history of severe penicillin allergy.
4
Educate patients about the importance of completing the full course of treatment.
5
Watch for neurological symptoms like confusion or seizures, particularly in elderly patients.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with chills
This medicine is used for severe bacterial infections that may cause fever.
Likely Use
❌
Common cold
This medicine is not effective against viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered intravenously or intramuscularly, so absorption is not applicable. It achieves high plasma concentrations rapidly after injection.
DistributionThis medicine distributes widely into body tissues and fluids, including the lungs, skin, urine, and bile. It penetrates into cerebrospinal fluid when the meninges are inflamed. Protein binding is approximately 20%.
Protein BindingApproximately 20%
MetabolismThis medicine is minimally metabolized in the body. It is primarily excreted unchanged.
Half-LifeApproximately 2 hours in adults with normal kidney function.
ExcretionThis medicine is primarily excreted unchanged in the urine by glomerular filtration. Renal clearance is approximately 100 mL/min.
BioavailabilityNot applicable for injectable forms; bioavailability is 100% when administered intravenously.
Onset of ActionRapid onset; peak plasma concentrations are achieved immediately after intravenous administration.
Peak Plasma TimeImmediately after intravenous injection; approximately 1-2 hours after intramuscular injection.
Duration of ActionThe duration of action depends on the dosing interval, typically 8 to 12 hours. Therapeutic levels are maintained with appropriate dosing.

How It Works

This medicine works by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the synthesis of the peptidoglycan layer, which is essential for bacterial cell wall integrity. As a result, the bacterial cell wall weakens, leading to cell lysis and death. Cefepime is stable against many beta-lactamases, enzymes that can inactivate other antibiotics, which contributes to its broad-spectrum activity.

Mechanism Steps

1
Binding to PBPs: This medicine binds to penicillin-binding proteins on the bacterial cell membrane.
2
Inhibition of cell wall synthesis: This binding inhibits the cross-linking of peptidoglycan chains, disrupting cell wall formation.
3
Bacterial cell lysis: The weakened cell wall leads to osmotic instability and bacterial cell death.

💡 How to Take ipacare 250mg injection

Strength: Injection: 250mg, 500mg, 1g, 2g vials

1This medicine is administered by a healthcare professional.
2It is given intravenously or intramuscularly.
3The dose and frequency are determined by your doctor.
4Do not attempt to self-administer.
5Follow your doctor's instructions for the duration of treatment.

Dosage Information

Adult DosageThe usual adult dose ranges from 1 to 2 grams every 8 to 12 hours, depending on the type and severity of infection. For severe infections, higher doses may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment is required in patients with renal impairment. The dose and/or frequency should be reduced based on creatinine clearance. Consult a clinician for specific recommendations.
Hepatic ImpairmentNo specific dose adjustment is required for hepatic impairment alone. However, dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 6 grams per day in adults with normal renal function.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Contact your healthcare provider for instructions.
💡 Do not self-administer.
📌 More than half the dosing interval has passed
→ Skip the missed dose and continue with the next scheduled dose.
💡 Do not double dose.

⚠️ Side Effects of ipacare 250mg injection

✅ Common Side Effects

Diarrhea (Common (1-10%))
Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (1-10%))
Take with food if possible. Consult doctor if persistent.
Rash (Common (1-10%))
Monitor for progression. Consult doctor if rash spreads or is accompanied by other symptoms.
Injection site pain (Common (1-10%))
Apply cold compress. Report to healthcare provider if severe.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of face or throat, or severe rash.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop severe diarrhea, abdominal pain, or fever.
Seizures (Rare (<0.1%))
Seek immediate medical attention if seizures occur.
Kidney impairment (Rare (<0.1%))
Report decreased urine output or swelling. Monitor kidney function regularly.

⚠️ Rare Side Effects

Blood disorders (e.g., neutropenia, thrombocytopenia)
Report unusual bruising or bleeding. Regular blood tests may be needed.
Liver enzyme elevations
Monitor liver function tests. Report yellowing of skin or eyes.
Neurological effects (e.g., encephalopathy)
Report confusion, hallucinations, or muscle twitching immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Aminoglycosides Major
Loop diuretics Major
Warfarin Moderate
Probenecid Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Aminoglycosides
  • Loop diuretics (e.g., furosemide)

⚡ Moderate Interactions

  • Warfarin
  • Probenecid

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset and should be avoided during treatment with this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to cefepime or other cephalosporins","Known hypersensitivity to penicillins (cross-reactivity)","Previous anaphylactic reaction to beta-lactam antibiotics"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment required.","May cause seizures, especially in patients with renal impairment.","May cause Clostridioides difficile-associated diarrhea.","Serious allergic reactions can occur.","Prolonged use may lead to superinfection.","Monitor for neurological effects in elderly patients."]

🤱 Lactation Safety

This medicine is excreted in human milk in low concentrations. Caution should be exercised when administered to a nursing woman. Consult your doctor.

💊 Overdose Management

Overdose may cause seizures, encephalopathy, and neuromuscular excitability. Treatment is symptomatic and supportive. Hemodialysis may be considered to remove cefepime from the blood in severe cases.

⏰ Missed Dose

Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your healthcare provider for instructions. Do not attempt to self-administer.

Additional Safety Advice

General Safety

This medicine should only be administered by a healthcare professional. Inform your doctor about any allergies, especially to antibiotics. Use with caution in patients with kidney disease, seizure disorders, or gastrointestinal problems. Complete the full course as prescribed, even if you feel better. Do not self-administer. Avoid alcohol during treatment. Report any signs of allergic reaction, severe diarrhea, or seizures immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of kidney impairment and neurological side effects. Dose adjustment based on renal function is often required. Monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used to prevent or treat surgical site infections. Follow your surgeon's instructions.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help flush out the infection.
🥗
Get plenty of rest to support your immune system.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Avoid alcohol during treatment.
🧘
Practice good hygiene to prevent reinfection.

🏋️ Exercise Considerations

Avoid strenuous exercise during treatment, especially if you feel weak or dizzy. Consult your doctor before resuming exercise.

🥗 Diet Recommendations

Drink plenty of fluids.
Eat probiotic-rich foods like yogurt to prevent diarrhea.
Avoid spicy and oily foods if you have stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. You may need to take time off work during treatment.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better. Stopping early may lead to recurrence of infection and antibiotic resistance.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance and superinfections. Prolonged use may also affect kidney function and blood counts. Regular monitoring is required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and susceptibility, other antibiotics like ceftriaxone or meropenem may be used.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about your vaccination status.

📦 Storage Guide

✅ DO

Store at room temperature (20-25°C)

❌ DON'T

Do not freeze

✅ DO

Protect from light

❌ DON'T

Do not use if solution is discolored or contains particles

✅ DO

Keep in original packaging

❌ DON'T

Do not transfer to unmarked containers

✈️ Traveling with This Medicine

This medicine is administered in a healthcare setting, so travel advice is limited. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed. Consult your doctor before travel if you have ongoing treatment.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man with pneumonia
He was admitted to the hospital with high fever and difficulty breathing. He was started on this medicine intravenously. His fever subsided within 48 hours, and he completed a 7-day course. He reported mild diarrhea, which resolved after treatment.
💡 Lesson: This medicine is effective for severe pneumonia but may cause mild gastrointestinal side effects.
👤 A 45-year-old woman with a complicated urinary tract infection
She had a history of recurrent UTIs and was allergic to penicillin. She was cautiously given this medicine after a test dose. Her infection cleared without any allergic reaction. She was advised to monitor for any delayed hypersensitivity.
💡 Lesson: This medicine can be used with caution in patients with penicillin allergy, but close monitoring is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working quickly after injection, but you may not feel better for a few days. Complete the full course as prescribed.

Q: Can I take this medicine at home?

A: No, this medicine must be administered by a healthcare professional in a hospital or clinic setting.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine if I have kidney disease?
  • Will this medicine interact with my other medications?
  • How long will I need to stay in the hospital?
  • Can I breastfeed while on this medicine?
  • What if I miss a dose?

🔄 Substitutes for ipacare 250mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections.
    Fact: This medicine is only effective against bacterial infections and does not treat viral infections.
  • Myth: This medicine is safe for everyone.
    Fact: This medicine can cause allergic reactions and should be avoided in patients with known allergies to cephalosporins or penicillins.

🔄 Alternative Options

Generic Alternatives

  • Cefepime injection

Brand Alternatives

  • Abdopime 250mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Cefepime","class":"Fourth-generation cephalosporin","route":"Parenteral","spectrum":"Broad-spectrum"},{"medicine":"Ceftriaxone","class":"Third-generation cephalosporin","route":"Parenteral","spectrum":"Broad-spectrum"},{"medicine":"Meropenem","class":"Carbapenem","route":"Parenteral","spectrum":"Very broad-spectrum"}]

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