Iopar-SR Capsule (Acetazolamide 250 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Rash, blisters, or peeling skin
- Unusual bleeding or bruising
- Severe abdominal pain or blood in vomit or stool
- Confusion, rapid breathing, or irregular heartbeat
- Decreased urine output or swelling in legs
- Severe headache with vision changes
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is iopar-sr capsule used for?
This medicine contains Acetazolamide 250 mg, a carbonic anhydrase inhibitor used to treat glaucoma, edema, epilepsy, and acute mountain sickness. It works by reducing fluid production in the eye and acting as a mild diuretic. It is a prescription medicine and should be taken exactly as directed by your doctor.
- Generic Name: Acetazolamide (250mg)
- Manufacturer: FDC Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 iopar-sr capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटाजोलामाइड 250 मिलीग्राम कैप्सूल है, जिसका उपयोग मुख्य रूप से ग्लूकोमा (आंखों में बढ़े हुए दबाव) को कम करने के लिए किया जाता है। यह शरीर में अतिरिक्त तरल पदार्थ को बाहर निकालने में मदद करती है और कुछ प्रकार के दौरे (मिर्गी) और ऊंचाई पर होने वाली बीमारी (अल्टीट्यूड सिकनेस) के इलाज और रोकथाम में भी उपयोग की जाती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हाथ-पैरों में झुनझुनी या सुन्नपन, बार-बार पेशाब आना, चक्कर आना, नींद आना, जी मिचलाना, उल्टी, दस्त और मुंह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन त्वचा पर गंभीर दाने, खून की बीमारी, गुर्दे की पथरी, मेटाबॉलिक एसिडोसिस और एलर्जी प्रतिक्रिया हो सकती है। यदि आपको त्वचा पर दाने, असामान्य रक्तस्राव, गंभीर पेट दर्द, भ्रम या तेज धड़कन महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से खुराक न बदलें और न ही दवा बंद करें। दिन भर पर्याप्त पानी पिएं ताकि गुर्दे की पथरी से बचाव हो सके। इस दवा के साथ शराब न लें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। धूप में बाहर निकलते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। नियमित जांच के लिए डॉक्टर के पास जाते रहें।
💊 iopar-sr capsule Uses & Benefits
[{"condition":"Glaucoma (open-angle and secondary)","description":"Lowers elevated intraocular pressure by reducing aqueous humor production, helping to prevent optic nerve damage.","evidence":"Well-established"},{"condition":"Acute angle-closure glaucoma","description":"Used as an adjunct to other treatments to rapidly reduce intraocular pressure during an acute attack.","evidence":"Well-established"},{"condition":"Edema due to heart failure","description":"Acts as a mild diuretic to help remove excess fluid in selected patients when other diuretics are not suitable.","evidence":"Established"},{"condition":"Epilepsy (adjunctive therapy)","description":"May be added to other anti-seizure medicines for certain seizure types, especially absence seizures.","evidence":"Established"},{"condition":"Acute mountain sickness (prevention and treatment)","description":"Helps prevent and reduce symptoms of altitude sickness by stimulating breathing and reducing fluid buildup.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Idiopathic intracranial hypertension","description":"Sometimes prescribed to reduce cerebrospinal fluid production and lower intracranial pressure.","evidence":"Limited"},{"condition":"Metabolic alkalosis","description":"Occasionally used to correct certain types of metabolic alkalosis under specialist supervision.","evidence":"Limited"},{"condition":"Periodic paralysis","description":"May be used in some forms of periodic paralysis to prevent attacks, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Glaucoma
Also treats: Edema due to heart failure, Epilepsy, Acute mountain sickness
📋 Drug Information
| Generic Name(s) | Acetazolamide (250mg) |
| Brand Name | iopar-sr capsule |
| Manufacturer | FDC Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Carbonic anhydrase inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the enzyme carbonic anhydrase in various tissues. In the eye, this reduces the secretion of aqueous humor, which lowers intraocular pressure. In the kidney, it increases the excretion of bicarbonate, sodium, potassium, and water, producing a mild diuretic effect. In the brain, it may help reduce cerebrospinal fluid production and alter pH, which can help in conditions like altitude sickness and certain seizures.
Mechanism Steps
💡 How to Take iopar-sr capsule
Strength: Acetazolamide 250 mg immediate-release capsule
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for glaucoma is 250 mg to 1000 mg per day, divided into one to four doses, depending on the severity of the condition and patient response. For acute mountain sickness, 125 mg to 250 mg twice daily may be used, starting 24 hours before ascent. For epilepsy, the dose ranges from 250 mg to 1000 mg per day in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and electrolyte imbalances. Dose should be individualized by a qualified clinician based on renal function and overall health status. |
| Renal Impairment | This medicine is excreted by the kidneys. In patients with renal impairment, the dose may need to be reduced. It is contraindicated in severe renal impairment. Consult a nephrologist or qualified clinician for individualized dosing. |
| Hepatic Impairment | This medicine is not significantly metabolized by the liver, but it should be used with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 1000 mg, but this may vary based on indication and clinical judgment. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of iopar-sr capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Salicylates | Major | |
| Lithium | Major | |
| Primidone | Major | |
| Amphetamines | Major | |
| Memantine | Major | |
| Corticosteroids | Moderate | |
| Diuretics | Moderate | |
| Digoxin | Moderate | |
| Methenamine | Moderate | |
| Carbamazepine | Moderate |
🚨 Major Interactions
- Salicylates (e.g., high-dose aspirin)
- Lithium
- Primidone
- Amphetamines
- Memantine
⚡ Moderate Interactions
- Corticosteroids
- Diuretics (e.g., thiazides, loop diuretics)
- Digoxin
- Methenamine
- Carbamazepine
🍷 Alcohol Interaction
Alcohol may increase the central nervous system side effects of this medicine, such as dizziness and drowsiness. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to acetazolamide or sulfonamides","Severe renal impairment or kidney failure","Severe hepatic impairment or cirrhosis","Hyperchloremic acidosis","Hypokalemia or hyponatremia","Adrenal insufficiency","Pregnancy (especially first trimester) unless clearly needed"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness and blurred vision. Avoid driving or operating machinery until you know how it affects you.","Drink plenty of water to prevent kidney stones.","This medicine may increase sensitivity to sunlight. Use sunscreen and protective clothing.","Monitor for signs of metabolic acidosis, such as rapid breathing, confusion, and fatigue.","Use with caution in patients with respiratory disease, especially chronic obstructive pulmonary disease, as it may cause acidosis.","This medicine may cause a decrease in blood counts. Report any signs of infection or unusual bleeding.","Do not use this medicine for prolonged periods without medical supervision."]
🤱 Lactation Safety
This medicine is excreted in breast milk. It is not known whether it affects the breastfed infant. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe metabolic acidosis, electrolyte imbalances, and central nervous system effects. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs, electrolytes, and blood gases. Hemodialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Drink plenty of water throughout the day to help prevent kidney stones. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Tell your doctor if you have kidney or liver problems, low potassium or sodium levels, or a history of kidney stones. This medicine may make your skin more sensitive to sunlight, so use sunscreen and protective clothing when outdoors. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep all follow-up appointments so your doctor can monitor your blood counts, electrolyte levels, and kidney function.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and electrolyte imbalances. Dose should be individualized based on renal function and overall health status. Regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Discuss alternative treatments if appropriate.
🏥 Post-Surgery Considerations
This medicine may interact with other medicines used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before certain surgeries.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or increased bleeding risk. Your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness and drowsiness. Avoid strenuous exercise or activities that require mental alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, dizziness, and blurred vision, which can affect your ability to drive or operate machinery. It may also cause increased urination, which can be inconvenient during work hours. Plan your doses accordingly and consult your doctor if side effects interfere with your daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Your doctor will determine if and when to stop the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to electrolyte imbalances, metabolic acidosis, kidney stones, and blood disorders. Regular monitoring of blood counts, electrolytes, and kidney function is recommended. Periodic eye examinations are necessary if used for glaucoma. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used for glaucoma with fewer systemic side effects.
Evidence: Well-establishedAnother class of medicines for glaucoma.
Evidence: Well-establishedGradual ascent and acclimatization can help prevent altitude sickness.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established from the available information. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 1 to 2 hours after taking a dose. The full effect on eye pressure may take a few hours.
A: Yes, taking it with food helps reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine should be used during pregnancy only if the potential benefit justifies the potential risk. Consult your doctor.
A: It is advisable to avoid alcohol as it can increase drowsiness and dizziness.
🤔 Common Patient Concerns
🔄 Substitutes for iopar-sr capsule
View AllAlternative brands with exact same active ingredient:
-
opt tabletSearch Orbis Pharmaceuticals ₹7.25 86.3% CHEAPER
-
actamide 250mg tabletMicro Labs Ltd ₹16.80 68.3% CHEAPER
-
zac 250mg tabletOscar Remedies Pvt Ltd ₹26.00 51% CHEAPER
-
actazid 250mg tabletOrtin Laboratories Ltd ₹30.00 43.4% CHEAPER
-
o mide 250mg tabletOptho Remedies Pvt Ltd ₹34.00 35.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for weight loss.
Fact: This medicine is a diuretic and can cause temporary fluid loss, but it is not approved for weight loss and can be dangerous if used for that purpose. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription-only medicine and should only be used under medical supervision. - Myth: You can stop taking this medicine once your symptoms improve.
Fact: You should not stop taking this medicine without consulting your doctor, as sudden discontinuation can worsen your condition.
🔄 Alternative Options
Generic Alternatives
- Acetazolamide 250 mg capsule
Brand Alternatives
- Iopar-SR Capsule