intramoto a 100mg/50000au tablet - Aceclofenac (100mg) + Trypsin Chymotrypsin (50000AU) medicine

Astofen TC Tablet: Complete Information on Uses, Side Effects, and Safety

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🏭 Intra Life 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. Avoid in third trimester. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is intramoto a 100mg/50000au tablet used for?

This medicine is a combination of Aceclofenac and Trypsin Chymotrypsin used to relieve pain, inflammation, and swelling in conditions like arthritis and post-surgical edema. It works by reducing prostaglandins and breaking down inflammatory proteins.

  • Generic Name: Aceclofenac (100mg) + Trypsin Chymotrypsin (50000AU)
  • Manufacturer: Intra Life
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 intramoto a 100mg/50000au tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटोक्लोफेनाक और ट्रिप्सिन काइमोट्रिप्सिन का संयोजन है, जिसका उपयोग दर्द, सूजन और जलन को कम करने के लिए किया जाता है। यह गठिया, जोड़ों के दर्द, सूजन और सर्जरी के बाद होने वाली सूजन में प्रभावी है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, अपच, सिरदर्द, चक्कर आना और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, गुर्दे की समस्या, यकृत विषाक्तता और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आपको पेट में अल्सर, गुर्दे या यकृत की बीमारी है, तो डॉक्टर को बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 intramoto a 100mg/50000au tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and inflammation in the spine and sacroiliac joints.","evidence":"Well-established"},{"condition":"Post-surgical inflammation","description":"Reduces swelling and pain after surgical procedures.","evidence":"Moderate"},{"condition":"Post-traumatic edema","description":"Helps resolve swelling and inflammation following injuries.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Dental pain","description":"Sometimes used for short-term relief of dental pain and swelling.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain relief.","evidence":"Limited"}]

Primary treatment for: Musculoskeletal pain and inflammation

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Post-surgical inflammation, Post-traumatic edema

📋 Drug Information

Generic Name(s)Aceclofenac (100mg) + Trypsin Chymotrypsin (50000AU)
Brand Nameintramoto a 100mg/50000au tablet
ManufacturerIntra Life
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration. Trypsin and chymotrypsin are absorbed in the intestine and reach systemic circulation. Food may slightly delay absorption but does not significantly affect the extent.
DistributionAceclofenac is highly protein-bound and distributes well into synovial fluid. Trypsin and chymotrypsin distribute to various tissues, especially at sites of inflammation.
Protein BindingAceclofenac is approximately 99% bound to plasma proteins. Trypsin and chymotrypsin binding is not well established.
MetabolismAceclofenac is metabolized in the liver primarily by CYP2C9 to inactive metabolites. Trypsin and chymotrypsin are metabolized by natural proteolytic processes.
Half-LifeThe elimination half-life of aceclofenac is approximately 4 hours. The half-life of trypsin and chymotrypsin is not well established.
ExcretionAceclofenac metabolites are excreted mainly in urine and to a lesser extent in feces. Trypsin and chymotrypsin are excreted as amino acids and peptides.
BioavailabilityThe oral bioavailability of aceclofenac is approximately 80-100%. Bioavailability of trypsin and chymotrypsin is not well established.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimePeak plasma concentration of aceclofenac is reached in about 1.5-2 hours.
Duration of ActionThe analgesic and anti-inflammatory effects last for approximately 12-24 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase enzyme, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Trypsin and chymotrypsin are proteolytic enzymes that hydrolyze proteins and help break down fibrin and other inflammatory debris, reducing edema and promoting tissue repair. Together, they provide both anti-inflammatory and anti-edematous effects.

Mechanism Steps

1
COX enzyme inhibition: Aceclofenac inhibits cyclooxygenase enzymes, reducing prostaglandin production.
2
Reduced prostaglandin synthesis: Lower prostaglandin levels decrease pain and inflammation at the site of injury.
3
Proteolytic enzyme action: Trypsin and chymotrypsin hydrolyze proteins involved in edema and inflammation.
4
Enhanced tissue repair: The breakdown of inflammatory debris promotes faster healing and reduces swelling.

💡 How to Take intramoto a 100mg/50000au tablet

Strength: Tablet containing Aceclofenac 100 mg and Trypsin Chymotrypsin 50000 AU.

1Take the tablet with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Do not lie down immediately after taking the tablet.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, preferably with food. The dose may be adjusted by your doctor based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 200 mg of aceclofenac (two tablets). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of intramoto a 100mg/50000au tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. Consult doctor if persistent.
Stomach pain (Common (5-10%))
Take with food or milk. Consult doctor if severe.
Indigestion (Common (5-10%))
Avoid spicy food. Consult doctor if persistent.
Headache (Common (5-10%))
Rest and hydrate. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid driving. Consult doctor if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Kidney problems (Rare (<0.1%))
Report decreased urine output or swelling. Seek medical attention.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine. Seek medical attention.
Severe allergic reactions (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, or throat, or difficulty breathing.
Cardiovascular events (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or weakness.

⚠️ Rare Side Effects

Blood disorders
Report unusual bleeding or bruising. Seek medical attention.
Pancreatitis
Seek immediate medical attention if you experience severe abdominal pain radiating to back.
Severe skin reactions
Seek emergency care if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
Antihypertensives Moderate
Diuretics Moderate
SSRIs Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • Antihypertensives
  • Diuretics
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding and may worsen liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to aceclofenac or any component","Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney disease","Severe liver disease","Third trimester of pregnancy","Children under 18 years"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma.","Do not take other NSAIDs concurrently.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, stomach pain, dizziness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Use with caution in elderly patients and those with bleeding disorders. Do not use this medicine for more than 7 days without medical advice. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use with caution and lower doses may be appropriate.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Avoid use during the third trimester. Use effective contraception if taking this medicine.

🏥 Post-Surgery Considerations

This medicine may be prescribed after surgery to reduce pain and swelling. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain and swelling. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take with food.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach pain, black stools, or allergic reactions. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal ulcers, bleeding, kidney impairment, and cardiovascular events. Regular monitoring of kidney and liver function is advised. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot and cold compresses

May help reduce local swelling and pain.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man recovering from knee surgery
Was prescribed this medicine for post-surgical swelling and pain. Noticed reduced swelling and improved mobility within a few days. Was advised to avoid alcohol and take with meals.
💡 Lesson: This medicine effectively reduces post-surgical edema and pain when taken as directed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30-60 minutes after taking the tablet.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs without consulting your doctor as it may increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for intramoto a 100mg/50000au tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term without any risk.
    Fact: Long-term use of NSAIDs can cause stomach ulcers, kidney problems, and heart issues. It should be used for the shortest duration possible.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with active ulcers, severe kidney or liver disease, or during the third trimester of pregnancy.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac + Trypsin Chymotrypsin combination generics

Brand Alternatives

  • Astofen TC Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Aceclofenac 100 mg + Trypsin Chymotrypsin 50000 AU","uses":"Pain, inflammation, edema","notes":"Combination provides anti-inflammatory and anti-edematous effects."},{"medicine":"Aceclofenac + Paracetamol","composition":"Aceclofenac 100 mg + Paracetamol 325 mg","uses":"Pain and fever","notes":"Paracetamol adds analgesic and antipyretic effect but no anti-edematous action."}]

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