intasol infusion - Sodium Chloride (0.49% w/v) + Sodium Lactate (0.39% w/v) medicine

Intasol Infusion: Complete Medical Guide

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🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Shortness of breath or difficulty breathing
  • Chest pain or palpitations
  • Swelling of face, lips, or throat
  • Severe headache with confusion
  • Decreased urine output
  • Pain, redness, or swelling at the infusion site
  • Fever with chills

If experiencing severe symptoms, call emergency services immediately.

What is intasol infusion used for?

This medicine is an intravenous fluid containing sodium chloride and sodium lactate. It is used to restore fluid volume, correct electrolyte imbalance, and treat metabolic acidosis in dehydrated or hypovolemic patients.

  • Generic Name: Sodium Chloride (0.49% w/v) + Sodium Lactate (0.39% w/v)
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 intasol infusion के बारे में (Hindi Summary)

उपयोग: यह दवा एक अंतःशिरा (IV) तरल पदार्थ है जिसमें सोडियम क्लोराइड और सोडियम लैक्टेट होता है। इसका उपयोग शरीर में तरल की कमी को पूरा करने, इलेक्ट्रोलाइट संतुलन बनाने और मेटाबॉलिक एसिडोसिस (शरीर में अम्लता बढ़ने) को ठीक करने के लिए किया जाता है। यह उन रोगियों के लिए दी जाती है जो उल्टी, दस्त, सर्जरी या चोट के कारण निर्जलित हो गए हैं। यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा IV लाइन के माध्यम से दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, लालिमा या सूजन, हल्का बुखार, ठंड लगना, जी मिचलाना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव कम होते हैं लेकिन तेजी से इन्फ्यूजन देने पर फेफड़ों में पानी भर सकता है, सोडियम की मात्रा बढ़ सकती है या एलर्जी हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर की देखरेख में दी जानी चाहिए। मरीज को अपनी सभी बीमारियों, खासकर हृदय, गुर्दे, यकृत और मधुमेह की जानकारी डॉक्टर को देनी चाहिए। इस दवा के साथ ली जाने वाली अन्य दवाओं के बारे में भी बताएं। इलाज के दौरान खून की जांच की जा सकती है। इन्फ्यूजन की गति को खुद से कम या ज्यादा न करें। इंजेक्शन की जगह पर दर्द, सूजन या लालिमा हो तो तुरंत बताएं। गर्भवती महिलाएं डॉक्टर को पहले बताएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 intasol infusion Uses & Benefits

[{"condition":"Hypovolemia and dehydration","description":"This medicine is used to restore intravascular volume and correct fluid deficits in patients who are dehydrated or have lost fluids due to vomiting, diarrhea, or excessive sweating.","evidence":"Well-established"},{"condition":"Metabolic acidosis","description":"The sodium lactate component is metabolized to bicarbonate, which helps to correct mild to moderate metabolic acidosis.","evidence":"Well-established"},{"condition":"Intraoperative and postoperative fluid management","description":"It is commonly used during surgery and in the postoperative period to maintain fluid and electrolyte balance.","evidence":"Well-established"},{"condition":"Fluid replacement in trauma and burns","description":"This medicine can be used as part of initial fluid resuscitation in trauma and burn patients, although additional electrolytes may be needed.","evidence":"Well-established"},{"condition":"Vehicle for intravenous drug administration","description":"It can serve as a compatible diluent for certain intravenous medications that require a sodium-containing solution.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]

Primary treatment for: Hypovolemia and dehydration

Also treats: Metabolic acidosis, Electrolyte imbalance, Surgical fluid management

📋 Drug Information

Generic Name(s)Sodium Chloride (0.49% w/v) + Sodium Lactate (0.39% w/v)
Brand Nameintasol infusion
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action Class
Route of AdministrationParenteral (intravenous infusion)
StorageStore at room temperature between 15°C and 30°C. Do not freeze. Keep in the original container until use. Protect from direct sunlight.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Assess the patient's fluid and electrolyte status before starting the infusion.
2
Monitor vital signs and urine output regularly during infusion.
3
Adjust the infusion rate based on the patient's age, weight, and cardiac status.
4
Check serum electrolytes and acid-base status periodically.
5
Use aseptic technique to prevent infection at the infusion site.
6
Be cautious in patients with heart failure or renal impairment to avoid fluid overload.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Dehydration
This medicine is commonly used to treat dehydration.
Likely Use
✅
Metabolic acidosis
This medicine helps correct metabolic acidosis.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered directly into the bloodstream, so absorption from the gastrointestinal tract does not apply. The infused ions and fluid are immediately available in the circulation.
DistributionThe sodium, chloride, and lactate ions distribute primarily within the extracellular fluid compartment. Sodium and chloride are largely confined to the extracellular space, while lactate is rapidly taken up by the liver and other tissues for metabolism. The volume of distribution depends on the patient's fluid status and body composition.
Protein BindingNot established from the available information.
MetabolismSodium chloride is not metabolized. Sodium lactate is metabolized primarily in the liver to bicarbonate and water through oxidative pathways. This conversion is rapid and is the basis for the alkalinizing effect of the solution.
Half-LifeNot established from the available information.
ExcretionSodium and chloride are excreted primarily by the kidneys, with renal excretion adjusted to maintain fluid and electrolyte balance. Lactate is metabolized rather than excreted unchanged, and the resulting bicarbonate is eliminated through renal and respiratory mechanisms. In patients with renal impairment, excretion of sodium and chloride may be prolonged, requiring careful monitoring.
BioavailabilityThis medicine is given intravenously, so its bioavailability is 100% by definition.
Onset of ActionThe onset of action is rapid, typically within minutes of starting the infusion, as the fluid and electrolytes enter the circulation directly.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action depends on the volume infused and the patient's clinical status. The effects on fluid balance generally last for several hours, while the buffering effect from lactate may persist until the lactate is fully metabolized.

How It Works

This medicine works by providing sodium, chloride, and lactate ions directly into the bloodstream. Sodium is the principal cation of extracellular fluid and is responsible for maintaining osmotic pressure and fluid balance. Chloride is the major anion and helps to maintain electrical neutrality. Lactate is converted in the liver to bicarbonate, which acts as a buffer to neutralize excess acid. The net effect is expansion of the extracellular fluid compartment, restoration of circulating blood volume, and correction of metabolic acidosis. Because the solution is isotonic, it does not cause significant shifts of water into or out of cells when given at appropriate rates.

Mechanism Steps

1
Infusion and distribution: The solution is infused intravenously and distributes primarily within the extracellular fluid compartment.
2
Sodium and chloride supplementation: Sodium and chloride ions are supplied to maintain osmotic pressure and electrical neutrality in the extracellular fluid.
3
Lactate metabolism: Lactate is taken up by the liver and converted to bicarbonate through oxidative metabolism.
4
Bicarbonate buffering: The generated bicarbonate buffers excess hydrogen ions, helping to correct metabolic acidosis.
5
Volume expansion: The net result is an increase in intravascular volume and improved tissue perfusion.

💡 How to Take intasol infusion

Strength: Intravenous infusion containing sodium chloride 0.49% w/v and sodium lactate 0.39% w/v.

1This medicine is given by a healthcare professional through an intravenous line.
2The infusion rate and volume are determined by the doctor based on your condition.
3You should not attempt to adjust the infusion rate yourself.
4Report any pain, swelling, or redness at the infusion site immediately.
5Blood tests may be done before and during treatment to monitor your electrolytes and kidney function.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the patient's clinical condition, fluid deficit, electrolyte status, and response to therapy. It is administered as an intravenous infusion, and the rate and volume are adjusted according to the patient's needs. Typical adult dosing may range from 500 mL to 1000 mL or more per day, but the exact amount must be determined by the treating doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to fluid overload and electrolyte imbalances. The dose should be carefully adjusted by a clinician, and renal and cardiac function should be monitored closely.
Renal ImpairmentIn patients with renal impairment, the dose and rate of infusion should be reduced, and electrolytes and renal function should be monitored frequently. This medicine may be contraindicated in severe renal impairment with oliguria or anuria.
Hepatic ImpairmentIn patients with hepatic impairment, lactate metabolism may be reduced, increasing the risk of metabolic alkalosis. The dose should be adjusted by a clinician, and acid-base status should be monitored.
Maximum Daily DoseThe maximum daily dose is not fixed and depends on the patient's clinical status. It must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Not applicable
Not applicable
This medicine is given intravenously and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Not applicable
→ This medicine is administered by healthcare professionals in a clinical setting.
💡 Missed doses are managed by the healthcare team.

⚠️ Side Effects of intasol infusion

✅ Common Side Effects

Injection site reactions such as pain, redness, or swelling (Common (5-10%))
Report to the healthcare team. The infusion site may need to be changed.
Mild fever or chills (Common (5-10%))
Usually resolves on its own. Inform the nurse or doctor if it persists.
Nausea (Common (5-10%))
Slow the infusion rate if possible and inform the healthcare team.
Headache (Common (5-10%))
Usually resolves. Report if severe or persistent.

🚨 Serious Side Effects

Fluid overload with pulmonary edema (Uncommon (0.1-1%))
Seek immediate medical attention if you experience shortness of breath, chest pain, or swelling.
Hypernatremia (Uncommon (0.1-1%))
Requires monitoring of sodium levels and adjustment of fluids.
Metabolic alkalosis (Rare (<0.1%))
Requires medical evaluation and possible change of fluid type.
Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Thrombophlebitis at the infusion site
Report pain, redness, or swelling along the vein to the healthcare team.
Extravasation causing tissue damage
Stop infusion immediately and inform the healthcare team.
Hypokalemia with prolonged use
Monitor potassium levels and supplement if needed.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Furosemide Major
Corticosteroids Major
Lithium Major
Antihypertensives Moderate
NSAIDs Moderate

🚨 Major Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Lithium

⚡ Moderate Interactions

  • Antihypertensive drugs
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

🍷 Alcohol Interaction

Alcohol may worsen dehydration and electrolyte imbalance. Patients receiving this medicine should avoid alcohol unless approved by their doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe hypernatremia","Severe metabolic alkalosis","Uncompensated heart failure","Severe renal impairment with oliguria or anuria","Known hypersensitivity to any component of the solution"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart failure, renal impairment, or conditions causing sodium retention.","Monitor electrolyte levels and acid-base status regularly during prolonged infusion.","Avoid rapid infusion to prevent fluid overload.","Do not use if the solution is cloudy or contains particles.","Ensure aseptic technique during administration to prevent infection."]

🤱 Lactation Safety

This medicine is considered compatible with breastfeeding. Sodium chloride and sodium lactate are normal constituents of breast milk and are not expected to harm the infant. However, nursing mothers should consult their doctor before receiving this medicine.

💊 Overdose Management

Overdose with this medicine can lead to fluid overload, hypernatremia, and metabolic alkalosis. Management includes stopping the infusion, monitoring vital signs and electrolytes, and providing supportive care. In severe cases, diuretics or dialysis may be required. Seek immediate medical attention if overdose is suspected.

⏰ Missed Dose

This medicine is given by a healthcare professional in a clinical setting, so missed doses are not applicable. If a scheduled infusion is missed, the healthcare team will determine the appropriate action based on the patient's condition.

Additional Safety Advice

General Safety

This medicine must be administered only by a trained healthcare professional in a clinical setting. Patients should inform their doctor about all medical conditions, especially heart failure, kidney disease, liver disease, diabetes, or any condition that causes fluid retention. It is important to tell the doctor about all medicines being taken, including diuretics, corticosteroids, and blood pressure medicines, because these can interact with the sodium and fluid balance. Blood tests may be needed before and during treatment to check electrolyte levels, kidney function, and acid-base status. Patients should not attempt to adjust the infusion rate or stop the infusion on their own. If any pain, swelling, redness, or leakage occurs at the infusion site, the healthcare team should be notified immediately. Pregnant women should inform their doctor before receiving this medicine, although it is generally considered safe when used appropriately. This medicine should be stored in its original container and should not be used if the solution is cloudy, discolored, or contains particles.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to fluid overload and electrolyte imbalances. The dose and rate of infusion should be carefully adjusted, and cardiac and renal function should be monitored closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, inform your doctor before receiving this medicine. It is generally considered safe when clinically indicated, but the decision should be made by a healthcare professional.

🏥 Post-Surgery Considerations

This medicine is often used after surgery to maintain fluid and electrolyte balance. Your doctor will determine the appropriate dose and duration based on your recovery.

🦷 Dental Procedures

If you are receiving this medicine, inform your dentist before any dental procedure. It is generally safe, but your dentist may consult with your doctor.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking adequate water unless your doctor restricts fluids.
🥗
Follow a balanced diet rich in electrolytes if advised.
😴
Monitor your weight daily if you have heart or kidney disease.
💧
Report any swelling or shortness of breath to your doctor promptly.
🧘
Avoid alcohol while receiving this medicine.

🏋️ Exercise Considerations

If you are receiving this medicine, consult your doctor before engaging in strenuous exercise. Exercise may affect fluid and electrolyte balance, and your doctor may recommend modifications based on your condition.

🥗 Diet Recommendations

Follow your doctor's advice regarding fluid and salt intake.
Include potassium-rich foods if your potassium levels are low, as advised.
Avoid excessive salt if you have hypertension or heart failure.

💼 Impact on Daily Work & Life

This medicine is given in a clinical setting, so it may require hospitalization or a clinic visit. It may cause mild drowsiness or dizziness in some patients. Avoid driving or operating machinery until you feel fully alert.

🛑 When to Stop This Medicine

This medicine should be stopped only on the advice of your doctor. Do not stop or adjust the infusion on your own. If you experience any serious side effects, inform your healthcare team immediately.

📅 Long-Term Use Effects

Prolonged use of this medicine without proper monitoring can lead to electrolyte imbalances, fluid overload, and metabolic alkalosis. It is important to have regular blood tests and clinical assessments to adjust therapy. Long-term use should be guided by a healthcare professional.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral rehydration therapy

For mild dehydration, oral rehydration solutions can be used instead of intravenous fluids.

Evidence: Well-established
Other intravenous fluids

Ringer's lactate or normal saline may be used depending on the clinical situation.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor that you are receiving this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not use if solution is cloudy or contains particles

✈️ Traveling with This Medicine

This medicine is given in a hospital or clinic setting, so travel advice is not applicable. If you are traveling and need intravenous fluids, ensure you carry a prescription and medical documentation. Store the solution at room temperature and protect it from extreme temperatures. Check with airlines and customs about carrying medical fluids.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man with severe dehydration due to gastroenteritis
He was admitted to the hospital with vomiting and diarrhea for two days. He was given this medicine intravenously. Within a few hours, his blood pressure improved, and he felt less weak. The doctors monitored his electrolytes and adjusted the infusion rate. He recovered well and was discharged the next day.
💡 Lesson: Timely intravenous fluid replacement with this medicine can rapidly correct dehydration and electrolyte imbalance.
👤 A 45-year-old woman undergoing abdominal surgery
She received this medicine during and after surgery to maintain fluid balance. The medical team monitored her urine output and electrolyte levels. She experienced mild nausea during the infusion, which resolved when the rate was slowed. She had an uneventful recovery.
💡 Lesson: This medicine is effective for perioperative fluid management, but side effects like nausea can be managed by adjusting the infusion rate.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within minutes of infusion, as it directly enters the bloodstream.

Q: Can I eat or drink while receiving this medicine?

A: Yes, unless your doctor advises otherwise. Food does not interact with this medicine.

Q: Will I need blood tests?

A: Yes, your doctor may order blood tests to monitor electrolytes, kidney function, and acid-base balance.

Q: Can this medicine cause allergic reactions?

A: Allergic reactions are rare but possible. Inform your doctor immediately if you experience rash, swelling, or difficulty breathing.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can this medicine be given at home?
  • What are the signs of fluid overload?
  • How often are blood tests needed during infusion?
  • Can this medicine be used in children?
  • Is this medicine safe in pregnancy?
  • What should I do if I feel pain at the infusion site?

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally.
    Fact: This medicine is for intravenous use only and must be given by a healthcare professional.
  • Myth: This medicine is a blood substitute.
    Fact: This medicine is a crystalloid fluid, not a blood product. It does not carry oxygen.
  • Myth: This medicine can be used for any type of dehydration.
    Fact: It is used for specific types of fluid loss and electrolyte imbalance. The doctor will decide if it is appropriate.

🔄 Alternative Options

Generic Alternatives

  • Sodium chloride 0.49% and sodium lactate 0.39% intravenous infusion

Brand Alternatives

  • intasol infusion

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Sodium chloride 0.49% + sodium lactate 0.39%","uses":"Fluid replacement, metabolic acidosis","route":"Intravenous"},{"medicine":"Ringer's lactate","composition":"Sodium chloride, sodium lactate, potassium chloride, calcium chloride","uses":"Fluid replacement, metabolic acidosis","route":"Intravenous"},{"medicine":"Normal saline","composition":"Sodium chloride 0.9%","uses":"Fluid replacement","route":"Intravenous"}]

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