Lupi-HMG 150 Injection: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain (more than 2 kg in a few days)
- Difficulty breathing or shortness of breath
- Severe pelvic pain
- Signs of allergic reaction (rash, itching, swelling, dizziness)
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is intas hmg 150i.u injection used for?
This medicine is a gonadotropin used to treat infertility by stimulating ovulation in women and sperm production in men.
- Generic Name: Menotrophin (150i.u)
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 intas hmg 150i.u injection के बारे में (Hindi Summary)
उपयोग: यह दवा पुरुषों और महिलाओं में बांझपन के इलाज के लिए इस्तेमाल की जाती है। यह महिलाओं में अंडाशय को उत्तेजित करके अंडे के उत्पादन को बढ़ावा देती है और पुरुषों में शुक्राणु उत्पादन को बढ़ाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन, पेट में असहजता, सिरदर्द और मूड स्विंग शामिल हैं। गंभीर दुष्प्रभावों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम (OHSS) शामिल है, जिसमें तेज पेट दर्द, वजन बढ़ना और सांस लेने में कठिनाई हो सकती है।
सुरक्षा सलाह: इस दवा का उपयोग केवल प्रजनन विशेषज्ञ की देखरेख में ही करें। नियमित अल्ट्रासाउंड और रक्त परीक्षण आवश्यक हैं। गंभीर पेट दर्द, सूजन या तेजी से वजन बढ़ने पर तुरंत डॉक्टर से संपर्क करें।
💊 intas hmg 150i.u injection Uses & Benefits
[{"condition":"Female infertility due to anovulation","description":"Stimulates follicular development and ovulation in women who do not ovulate naturally.","evidence":"Well-established"},{"condition":"Controlled ovarian hyperstimulation for assisted reproductive technologies (ART)","description":"Used to induce multiple follicular development for procedures such as IVF, GIFT, and ZIFT.","evidence":"Well-established"},{"condition":"Male hypogonadotropic hypogonadism","description":"Stimulates spermatogenesis in men with low gonadotropin levels.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Unexplained infertility","description":"Sometimes used empirically to enhance fertility when no clear cause is identified.","evidence":"Limited"}]
Primary treatment for: Infertility
Also treats: Anovulation, Hypogonadotropic hypogonadism
📋 Drug Information
| Generic Name(s) | Menotrophin (150i.u) |
| Brand Name | intas hmg 150i.u injection |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Gonadotropins |
| Route of Administration | Parenteral (subcutaneous or intramuscular injection) |
| Storage | Store refrigerated at 2-8°C. Do not freeze. Protect from light. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Menotrophin contains follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity. It binds to FSH and LH receptors on ovarian granulosa cells and testicular Leydig cells, stimulating follicular growth and maturation in women and spermatogenesis in men.
Mechanism Steps
💡 How to Take intas hmg 150i.u injection
Strength: Lyophilized powder for injection, 150 IU per vial.
Dosage Information
| Adult Dosage | Dosage is individualized based on indication, ovarian response, and treatment protocol. Typically, 75-150 IU daily is started, and adjusted according to ultrasound and estradiol levels. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Not applicable for fertility treatment in elderly. |
| Renal Impairment | No specific dose adjustment established. Use with caution. |
| Hepatic Impairment | No specific dose adjustment established. Use with caution. |
| Maximum Daily Dose | Not established from the available information. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of intas hmg 150i.u injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| GnRH antagonists | Major | |
| Clomiphene | Major | |
| Diuretics | Moderate |
🚨 Major Interactions
- Gonadotropin-releasing hormone (GnRH) antagonists
- Clomiphene citrate
⚡ Moderate Interactions
- Diuretics
🍷 Alcohol Interaction
Alcohol may impair fertility and should be avoided during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to menotrophin or any component","Primary ovarian failure","Primary testicular failure","Uncontrolled thyroid or adrenal dysfunction","Intracranial lesions","Abnormal genital bleeding of unknown cause","Pregnancy","Lactation"]
⚠️ Warnings & Precautions
["Use only under specialist supervision.","Monitor for OHSS.","Risk of multiple pregnancies.","May increase risk of ectopic pregnancy.","Not for self-administration without training."]
🤱 Lactation Safety
Not recommended during breastfeeding. Consult your doctor.
💊 Overdose Management
Overdose may lead to severe OHSS. Treatment is symptomatic and supportive. Seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, contact your doctor for guidance. Do not double the dose.
Additional Safety Advice
This medicine must be used only under the supervision of a fertility specialist. Do not self-administer unless you have been properly trained. Regular monitoring with ultrasound and blood tests is essential to assess ovarian response and adjust the dose. Report any severe abdominal pain, bloating, or rapid weight gain immediately, as these may be signs of ovarian hyperstimulation syndrome. Use effective contraception if you are not trying to conceive, as this medicine can increase the chance of multiple pregnancies. Avoid alcohol and smoking while undergoing fertility treatment. Inform your doctor if you have a history of ovarian cysts, thyroid disorders, or allergies. Store the product as directed and never use if the solution is discolored or contains particles.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Not applicable for fertility treatment in elderly.
🤰 Pregnancy Planning (TTC)
This medicine is used to achieve pregnancy. If you become pregnant, stop the medicine and inform your doctor immediately.
🏥 Post-Surgery Considerations
No specific considerations. Consult your doctor.
🦷 Dental Procedures
No specific considerations. Inform your dentist about this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during ovarian stimulation to reduce the risk of ovarian torsion. Light activities like walking are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or mood swings; avoid driving or operating machinery if affected. Fertility treatment can be emotionally and physically demanding; consider taking time off for appointments.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Your doctor will determine when to stop based on your response and treatment goals.
📅 Long-Term Use Effects
Long-term use may increase the risk of ovarian tumors, although evidence is not conclusive. Regular monitoring is required. Discuss with your doctor about the duration of treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral medication for ovulation induction.
Evidence: Well-establishedAn oral aromatase inhibitor used for ovulation induction.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions reported. Consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store refrigerated at 2-8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store at room temperature for prolonged periods
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, refrigerated condition during travel. Inform security personnel if carrying syringes. Plan for time zone adjustments if needed, and consult your doctor for specific instructions.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ovarian response typically begins within 5-7 days, but individual response varies. Your doctor will monitor your progress.
A: Common side effects include injection site pain, bloating, headache, and mood swings.
A: No, this medicine is contraindicated during pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for intas hmg 150i.u injection
View AllAlternative brands with exact same active ingredient:
-
menonys 150i.u injectionSanzyme Ltd ₹537.50 64.7% CHEAPER
-
zyhmg 150i.u injectionZydus Cadila ₹986.00 35.3% CHEAPER
-
menodac 150i.u injectionBayer Zydus Pharma Pvt Ltd ₹1,080.00 29.1% CHEAPER
-
ovumain-hp 150i.u injectionIntas Pharmaceuticals Ltd ₹1,442.31 5.3% CHEAPER
-
ovugraf hp 150i.u injectionVhb Life Sciences Inc ₹1,600.00 5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: It improves fertility but does not guarantee pregnancy. - Myth: This medicine can be taken without monitoring.
Fact: It requires close monitoring by a fertility specialist.
🔄 Alternative Options
Generic Alternatives
- Menotrophin 150 IU injection
Brand Alternatives
- Lupi-HMG 150 Injection