Intas FSH 150 IU Injection: A Complete Guide to Urofollitropin
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain (more than 2 kg in 24 hours)
- Difficulty breathing or shortness of breath
- Decreased urine output
- Severe headache with visual changes
- Swelling of face, lips, or throat
- Chest pain or leg pain with swelling
If experiencing severe symptoms, call emergency services immediately.
What is intas fsh 150i.u injection used for?
This medicine contains urofollitropin, a follicle-stimulating hormone (FSH) used to treat infertility by stimulating the ovaries to produce eggs or the testes to produce sperm. It is given by injection under the supervision of a fertility specialist.
- Generic Name: Urofollitropin (150i.u)
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 intas fsh 150i.u injection के बारे में (Hindi Summary)
उपयोग: यह दवा यूरोफॉलिट्रोपिन नामक हार्मोन से बनी है, जो महिलाओं में अंडाशय को उत्तेजित करके अंडे बनाने में मदद करती है और पुरुषों में शुक्राणु उत्पादन को बढ़ावा देती है। इसका उपयोग बांझपन के इलाज में किया जाता है, जैसे कि पीसीओएस, आईवीएफ और हाइपोगोनाडोट्रोपिक हाइपोगोनाडिज्म में। यह इंजेक्शन के रूप में दी जाती है और इसे केवल विशेषज्ञ की देखरेख में ही लिया जाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, सूजन, सिरदर्द, पेट में हल्की तकलीफ और अंडाशय का बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम (ओएचएसएस) हो सकता है, जिसमें तेज पेट दर्द, वजन बढ़ना, सांस लेने में कठिनाई और पेशाब कम आना शामिल है। कभी-कभी एलर्जी भी हो सकती है।
सुरक्षा सलाह: इस दवा का उपयोग केवल प्रजनन विशेषज्ञ की देखरेख में ही करें। बिना प्रशिक्षण के स्वयं इंजेक्शन न लगाएं। नियमित अल्ट्रासाउंड और रक्त परीक्षण से अंडाशय की प्रतिक्रिया की निगरानी करें। तेज पेट दर्द, सूजन या वजन बढ़ने पर तुरंत डॉक्टर से संपर्क करें। धूम्रपान और शराब से बचें। दवा को सही तापमान पर रखें और दूसरों के साथ साझा न करें।
💊 intas fsh 150i.u injection Uses & Benefits
[{"condition":"Ovulation induction in women with polycystic ovary syndrome (PCOS) or other ovulatory disorders","description":"Used to stimulate the development and release of a mature egg in women who do not ovulate regularly.","evidence":"Well-established"},{"condition":"Controlled ovarian hyperstimulation for in vitro fertilization (IVF) and other assisted reproductive technologies","description":"Used to stimulate multiple follicles to mature so that multiple eggs can be retrieved for fertilization.","evidence":"Well-established"},{"condition":"Hypogonadotropic hypogonadism in men","description":"Used to stimulate spermatogenesis in men with low gonadotropin levels, often in combination with human chorionic gonadotropin (hCG).","evidence":"Established"}]
Off-label uses: [{"condition":"Luteal phase support","description":"Sometimes used off-label to support the luteal phase in assisted reproduction cycles, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Infertility due to ovulatory dysfunction or need for controlled ovarian hyperstimulation
Also treats: Polycystic ovary syndrome (PCOS), Hypogonadotropic hypogonadism in men
📋 Drug Information
| Generic Name(s) | Urofollitropin (150i.u) |
| Brand Name | intas fsh 150i.u injection |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Gonadotropins |
| Route of Administration | Parenteral (subcutaneous or intramuscular injection) |
| Storage | Store the lyophilized powder at 2°C to 8°C (refrigerate). Do not freeze. Store the solvent at room temperature. After reconstitution, use immediately or store as directed by the manufacturer. Protect from light. |
| Shelf Life | Refer to the packaging for the expiry date. Typically 24 months from the date of manufacture when stored properly. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Urofollitropin is a follicle-stimulating hormone (FSH) that binds to FSH receptors on the surface of granulosa cells in the ovaries. This binding activates the receptor and stimulates intracellular signaling pathways, primarily the cyclic AMP (cAMP) pathway, which promotes follicular growth, granulosa cell proliferation, and estrogen production. In men, FSH acts on Sertoli cells in the testes to stimulate spermatogenesis. The medicine provides exogenous FSH to supplement or replace endogenous FSH when the pituitary gland does not produce enough.
Mechanism Steps
💡 How to Take intas fsh 150i.u injection
Strength: Lyophilized powder for injection, 150 IU per vial, with solvent for reconstitution.
Dosage Information
| Adult Dosage | The dose of this medicine is highly individualized and must be determined by a fertility specialist based on the patient's medical history, ovarian response, and treatment protocol. For ovulation induction, a common starting dose is 75 to 150 IU per day, administered subcutaneously or intramuscularly, with adjustments based on ultrasound and estradiol levels. For controlled ovarian hyperstimulation in IVF, doses may range from 150 to 300 IU per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not intended for use in elderly patients. Safety and efficacy have not been established. |
| Renal Impairment | No specific dose adjustments are established for renal impairment. Use with caution and monitor closely. |
| Hepatic Impairment | No specific dose adjustments are established for hepatic impairment. Use with caution and monitor closely. |
| Maximum Daily Dose | The maximum daily dose is determined by the clinician based on individual response. Doses above 450 IU per day are not recommended without specialist supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of intas fsh 150i.u injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| GnRH antagonists | Major | |
| hCG | Major | |
| Clomiphene | Moderate |
🚨 Major Interactions
- Gonadotropin-releasing hormone (GnRH) antagonists
- Human chorionic gonadotropin (hCG)
⚡ Moderate Interactions
- Clomiphene citrate
🍷 Alcohol Interaction
Alcohol may reduce fertility and should be avoided while undergoing fertility treatment. It can also worsen side effects such as headache and mood swings.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to urofollitropin or any component of the formulation","Primary ovarian failure","Uncontrolled thyroid or adrenal dysfunction","Intracranial lesion such as pituitary tumor","Abnormal uterine bleeding of unknown cause","Ovarian cysts or enlargement not due to polycystic ovary syndrome","Primary testicular failure in men"]
⚠️ Warnings & Precautions
["This medicine should only be prescribed by a fertility specialist.","Ovarian hyperstimulation syndrome (OHSS) can be life-threatening; monitor closely.","Multiple pregnancies are a risk; discuss with your doctor.","Thromboembolic events have been reported; use with caution in patients with risk factors.","Do not use if you are already pregnant.","In men, monitor for signs of androgen deficiency or prostate changes.","Use with caution in patients with renal or hepatic impairment."]
🤱 Lactation Safety
Not established from the available information. This medicine is not intended for use during breastfeeding.
💊 Overdose Management
Overdose may lead to severe ovarian hyperstimulation syndrome (OHSS). Treatment is supportive and may include hospitalization, intravenous fluids, and monitoring of electrolytes and coagulation. In case of overdose, seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is within a few hours of the scheduled time. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. Consult your fertility clinic for specific instructions.
Additional Safety Advice
This medicine must only be used under the care of a fertility specialist. Do not self-administer unless you have been trained to do so. Regular monitoring with ultrasound and blood tests is essential to assess ovarian response and adjust the dose. Report any severe abdominal pain, bloating, or rapid weight gain immediately. Use effective contraception if you are not trying to conceive, as this medicine can increase the chance of multiple pregnancies. Avoid alcohol and smoking as they can reduce fertility. Store the powder and solvent as directed and use immediately after reconstitution. Do not share this medicine with others.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly patients. Safety and efficacy have not been established in this population.
🤰 Pregnancy Planning (TTC)
This medicine is used to help you conceive. If you are planning pregnancy, your doctor will monitor your cycle closely. Once pregnancy is confirmed, discontinue this medicine. Discuss any concerns with your fertility specialist.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your doctor before starting this medicine. There is no specific contraindication, but your overall health status should be evaluated.
🦷 Dental Procedures
No specific precautions are required for dental procedures while on this medicine. However, inform your dentist about your medication and fertility treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during ovarian stimulation as it may increase the risk of ovarian torsion. Light activities like walking are generally safe. Consult your doctor before starting any exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mild fatigue, mood swings, or abdominal discomfort, which can affect daily activities. However, most women can continue their normal routine. If you experience severe symptoms, rest and consult your doctor. Avoid driving if you feel dizzy or unwell.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your fertility specialist. Treatment is stopped when the desired ovarian response is achieved or if complications occur. If you become pregnant, discontinue immediately and inform your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is generally limited to the duration of fertility treatment cycles. There is no established evidence of long-term adverse effects beyond the treatment period. However, repeated cycles may increase the risk of ovarian hyperstimulation syndrome and multiple pregnancies. Regular monitoring is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral medication for ovulation induction, often used as first-line treatment.
Evidence: Well-establishedAn oral aromatase inhibitor used for ovulation induction, especially in PCOS.
Evidence: Well-establishedWeight loss, diet, and exercise can improve fertility in some cases.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, it is advisable to be up to date on routine vaccinations before starting fertility treatment. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store the powder in the refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze the powder or the reconstituted solution
✅ DO
Keep the vial in the original carton to protect from light
❌ DON'T
Do not store at room temperature for prolonged periods
✅ DO
Use the reconstituted solution immediately or as directed
❌ DON'T
Do not use if the solution is cloudy or has particles
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label. Keep it refrigerated (2°C to 8°C) during travel using a cooler bag with ice packs. Do not freeze. Carry a copy of your prescription and a letter from your doctor explaining the medical need. Check airline regulations for carrying injections and sharps. If traveling across time zones, consult your doctor about adjusting injection timing.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Follicular growth usually starts within 5 to 7 days, but the full treatment cycle may last 10 to 14 days. Your doctor will monitor your response with ultrasound and blood tests.
A: Yes, after proper training from your healthcare provider. Make sure you understand the technique and follow sterile precautions.
A: If you miss a dose, take it as soon as you remember if it is within a few hours. If it is almost time for the next dose, skip it and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for intas fsh 150i.u injection
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ovufol hp 150iu injectionVhb Life Sciences Inc ₹1,478.00 17.9% CHEAPER
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ovitrop hp 150i.u injectionSun Pharmaceutical Industries Ltd ₹1,734.38 3.6% CHEAPER
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ovitrop 150i.u injectionSun Pharmaceutical Industries Ltd ₹1,734.38 3.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: This medicine increases the chance of pregnancy but does not guarantee it. Success rates vary based on age, cause of infertility, and other factors. - Myth: This medicine is safe to take without monitoring.
Fact: This medicine requires close monitoring by a fertility specialist to avoid serious complications like ovarian hyperstimulation syndrome.
🔄 Alternative Options
Generic Alternatives
- Urofollitropin
Brand Alternatives
- Intas FSH 150 IU Injection