Huminsulin N 100IU/ml Cartridge: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe low blood sugar with confusion, seizures, or loss of consciousness
- Swelling of the face, lips, throat, or difficulty breathing
- Signs of low potassium such as muscle weakness or irregular heartbeat
- Persistent high blood sugar with nausea, vomiting, or fruity breath
- Severe injection site reaction with pus, severe pain, or spreading redness
- Sudden vision changes or severe headache
If experiencing severe symptoms, call emergency services immediately.
What is insulatard 100iu/ml flexpen used for?
This medicine is an intermediate-acting human insulin used to control blood sugar in diabetes. It is injected under the skin, usually once or twice daily, and works by helping glucose enter cells and reducing liver glucose production.
- Generic Name: Insulin Isophane (100IU/ml)
- Manufacturer: Novo Nordisk India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 insulatard 100iu/ml flexpen के बारे में (Hindi Summary)
उपयोग: यह दवा इंसुलिन आइसोफेन का एक इंजेक्शन है जो मधुमेह (डायबिटीज) में रक्त शर्करा को नियंत्रित करने के लिए उपयोग की जाती है। यह मध्यम अवधि तक काम करने वाली इंसुलिन है, जिसे त्वचा के नीचे इंजेक्ट किया जाता है। यह शरीर में ग्लूकोज को कोशिकाओं तक पहुंचाने और लिवर द्वारा ग्लूकोज बनाने को कम करने में मदद करती है। इसे आमतौर पर दिन में एक या दो बार लिया जाता है। यह उन लोगों के लिए है जिनका शरीर पर्याप्त इंसुलिन नहीं बना पाता या जिनकी दवाइयां रक्त शर्करा को नियंत्रित नहीं कर पातीं। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा का सबसे आम दुष्प्रभाव है रक्त शर्करा का कम होना (हाइपोग्लाइसीमिया)। इसके लक्षणों में कंपकंपी, पसीना आना, भ्रम, तेज धड़कन, भूख लगना और चिड़चिड़ापन शामिल हैं। इंजेक्शन लगाने की जगह पर लालिमा, सूजन, खुजली या दर्द भी हो सकता है। कुछ लोगों में इंजेक्शन की जगह पर चर्बी जमा हो सकती है या गड्ढा बन सकता है। गंभीर दुष्प्रभावों में तेज एलर्जी, सांस लेने में कठिनाई, चेहरे या गले में सूजन शामिल हैं। अगर आपको कोई भी दुष्प्रभाव परेशान करे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग करते समय अपनी रक्त शर्करा की नियमित जांच करें। हमेशा अपने पास ग्लूकोज की गोलियां या मीठा फल का रस रखें ताकि कम शर्करा होने पर तुरंत इलाज किया जा सके। अपनी इंसुलिन पेन या कार्ट्रिज किसी और के साथ साझा न करें, क्योंकि इससे संक्रमण फैल सकता है। इंजेक्शन की जगह बदल-बदल कर लगाएं। अगर कार्ट्रिज खराब, जमी हुई या धुंधली दिखे तो उसका उपयोग न करें। बिना इस्तेमाल की कार्ट्रिज को फ्रिज में 2°C से 8°C के बीच रखें और कभी फ्रीज न करें। इस्तेमाल के बाद कार्ट्रिज को 28 दिनों तक कमरे के तापमान पर रखा जा सकता है। डॉक्टर की सलाह के बिना अपनी खुराक न बदलें और न ही दवा बंद करें।
💊 insulatard 100iu/ml flexpen Uses & Benefits
[{"condition":"Type 1 diabetes mellitus","description":"Provides intermediate-acting basal insulin to control blood sugar throughout the day and night in people who cannot produce insulin.","evidence":"Well-established"},{"condition":"Type 2 diabetes mellitus","description":"Used when oral medicines and other injectables are not enough to achieve target blood sugar levels, often as part of a basal-bolus regimen.","evidence":"Well-established"},{"condition":"Gestational diabetes","description":"May be prescribed when diet and exercise fail to control blood sugar during pregnancy, under close medical supervision.","evidence":"Well-established"},{"condition":"Diabetes in hospitalized patients","description":"Used in some hospital settings for blood sugar control, though short-acting insulins are often preferred for acute management.","evidence":"Established"}]
Off-label uses: [{"condition":"Hyperkalemia","description":"Sometimes used with glucose to shift potassium into cells in emergency situations, but this is not a standard use for this intermediate-acting form.","evidence":"Limited"}]
Primary treatment for: Diabetes mellitus
Also treats: Type 1 diabetes, Type 2 diabetes, Gestational diabetes
📋 Drug Information
| Generic Name(s) | Insulin Isophane (100IU/ml) |
| Brand Name | insulatard 100iu/ml flexpen |
| Manufacturer | Novo Nordisk India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Human insulin- intermediate acting |
| Route of Administration | Subcutaneous injection only. This medicine is injected into the fatty tissue just under the skin, usually in the abdomen, thigh, or upper arm. It must not be given into a vein or muscle |
| Storage | Store unused cartridges in the refrigerator between 2°C and 8°C. Do not freeze. Once in use, keep the cartridge at room temperature below 30°C for up to 28 days. Protect from direct sunlight and heat. Do not use if the cartridge has been frozen or exposed to extreme temperatures. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture when stored properly in the refrigerator. Once in use, discard after 28 days even if there is medicine left. Check the expiry date on the cartridge before use. |
| WHO Guideline | The World Health Organization includes human insulin, including intermediate-acting forms, in its Model List of Essential Medicines for the treatment of diabetes. Guidelines recommend individualized insulin therapy based on patient needs. |
| ICMR Guideline | The Indian Council of Medical Research recommends insulin therapy for people with diabetes when oral agents are insufficient, with dose adjustments based on blood sugar monitoring and individual factors. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to insulin receptors on the surface of muscle and fat cells. Once bound, it activates a series of signals inside the cell that move glucose transporters to the cell surface, allowing glucose to enter. It also signals the liver to stop making glucose and to store it as glycogen. Because the insulin is combined with protamine in a suspension, it is absorbed slowly from the injection site, giving a longer duration of action than regular human insulin. This provides a steady background level of insulin between meals and overnight.
Mechanism Steps
💡 How to Take insulatard 100iu/ml flexpen
Strength: Insulin isophane 100 IU/ml cartridge for subcutaneous injection.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on your blood sugar levels, diet, exercise, and other medicines. It is usually given once or twice daily as a subcutaneous injection. Your doctor will start with a low dose and adjust gradually to reach your target blood sugar. Do not change your dose without medical advice. Always follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Older adults may be more sensitive to the blood sugar-lowering effects of this medicine and may have a higher risk of hypoglycemia. Doses should be individualized by a clinician, and blood sugar should be monitored closely. Kidney function often declines with age, which can affect insulin clearance. |
| Renal Impairment | Kidney disease can reduce insulin clearance and increase the risk of low blood sugar. Your doctor may need to lower your dose. Monitor blood sugar more frequently if you have kidney problems. |
| Hepatic Impairment | Liver disease can affect insulin metabolism and increase the risk of low blood sugar. Your doctor may need to adjust your dose. Monitor blood sugar closely if you have liver problems. |
| Maximum Daily Dose | The maximum daily dose is determined by your doctor based on your individual needs. There is no fixed maximum, but doses are adjusted to achieve target blood sugar without causing hypoglycemia. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of insulatard 100iu/ml flexpen
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sulfonylureas | Major | |
| Beta-blockers | Major | |
| Corticosteroids | Major | |
| Alcohol | Major | |
| Thiazide diuretics | Moderate | |
| Thyroid hormones | Moderate | |
| MAO inhibitors | Moderate | |
| ACE inhibitors | Minor | |
| Fibrates | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Oral antidiabetic drugs (e.g., sulfonylureas)
- Beta-blockers
- Corticosteroids
- Alcohol
⚡ Moderate Interactions
- Thiazide diuretics
- Thyroid hormones
- MAO inhibitors
🍷 Alcohol Interaction
Drinking alcohol while using this medicine can cause dangerous drops in blood sugar, especially if you drink on an empty stomach. Alcohol can also mask the symptoms of low blood sugar, making it harder to recognize. It is best to limit alcohol intake and always check your blood sugar before and after drinking. Never drink alcohol without eating food.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypoglycemia (low blood sugar)","Allergy to insulin isophane or any ingredient in the cartridge","Diabetic ketoacidosis (unless under close medical supervision)","Not for intravenous or intramuscular injection"]
⚠️ Warnings & Precautions
["Never share your insulin pen or cartridge with others, even with a new needle, as it can transmit infections.","Do not use this medicine if the cartridge is damaged, frozen, or if the liquid is cloudy or contains particles.","Rotate injection sites to prevent lipodystrophy.","Alcohol can increase the risk of hypoglycemia; limit intake and never drink on an empty stomach.","Illness, stress, or surgery can change your insulin requirements; monitor blood sugar more often during these times.","Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Keep a source of fast-acting sugar with you at all times.","Do not drive or operate machinery if you have symptoms of low blood sugar."]
🤱 Lactation Safety
Insulin is safe to use while breastfeeding. It passes into breast milk in very small amounts and is not expected to harm the baby. However, breastfeeding can lower blood sugar, so monitor your levels and adjust your dose as advised by your doctor.
💊 Overdose Management
An overdose of this medicine can cause severe low blood sugar, which can be life-threatening. Symptoms include confusion, seizures, loss of consciousness, and coma. If you suspect an overdose, check your blood sugar immediately. If you are conscious and able to swallow, eat or drink something sugary. If you are unconscious or cannot swallow, someone should call emergency services right away. Glucagon injection may be given if available. Always inform medical staff about your insulin use.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. Check your blood sugar more often on the day you miss a dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Always check your blood sugar regularly while using this medicine, especially before meals and at bedtime. Keep a fast-acting source of sugar, such as glucose tablets or fruit juice, with you at all times to treat low blood sugar. Never share your insulin pen or cartridge with another person, even if the needle is changed, because this can spread infections. Rotate your injection sites within the same area to prevent skin problems. Do not use this medicine if the cartridge is damaged, the liquid looks cloudy or has particles, or if it has been frozen. Store unused cartridges in the refrigerator between 2°C and 8°C, and never freeze them. Once in use, a cartridge can be kept at room temperature for up to 28 days, away from direct heat and sunlight. Tell your doctor about all other medicines you take, including over-the-counter products, because many drugs can affect blood sugar. Do not drive or operate heavy machinery if you feel signs of low blood sugar. If you are planning pregnancy, are pregnant, or are breastfeeding, speak to your doctor about adjusting your insulin dose. Never change your dose or stop this medicine without consulting your healthcare provider.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to insulin and have a higher risk of low blood sugar. Kidney function often declines with age, which can prolong insulin action. Doses should be individualized, and blood sugar should be monitored frequently. Symptoms of low blood sugar may be less obvious in older adults.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. Good blood sugar control before and during pregnancy is important for the health of both mother and baby. Insulin is the preferred treatment for diabetes in pregnancy. Your dose may need to be adjusted during pregnancy.
🏥 Post-Surgery Considerations
After surgery, blood sugar can be difficult to control due to stress and changes in diet. Your insulin dose may need adjustment. Follow your doctor's instructions for monitoring and dosing. Inform your surgical team about your insulin use.
🦷 Dental Procedures
Inform your dentist about your diabetes and insulin use before any dental procedure. Dental work can affect your eating schedule, so you may need to adjust your insulin dose. Check your blood sugar before and after the procedure. Good dental hygiene is important for people with diabetes.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar and increase the risk of hypoglycemia. Check your blood sugar before exercising. If it is low, eat a snack first. You may need to adjust your insulin dose or snack before exercise. Consult your doctor for an exercise plan that suits you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may affect your ability to drive or operate machinery if you experience low blood sugar. Always check your blood sugar before driving. Keep a sugar source in your vehicle. Inform your employer about your diabetes and insulin use in case of emergency. With good control, most people can continue their normal work and daily activities.
🛑 When to Stop This Medicine
Do not stop using this medicine without consulting your doctor. Stopping insulin suddenly can cause dangerous high blood sugar and diabetic ketoacidosis. If you experience severe side effects or your treatment plan changes, your doctor will advise you on how to safely adjust or stop the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine can help prevent diabetes complications such as eye, kidney, and nerve damage when blood sugar is well controlled. However, it can also cause weight gain and increase the risk of low blood sugar. Regular monitoring of blood sugar, kidney function, and injection sites is important. Your doctor may adjust your dose over time based on your needs.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A device that delivers rapid-acting insulin continuously under the skin, which can be an alternative to multiple daily injections.
Evidence: Well-establishedInsulins like glargine or degludec provide a flatter, more predictable basal insulin profile.
Evidence: Well-establishedFor type 2 diabetes, oral medicines may be used along with or instead of insulin in some cases.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Vaccinations are generally safe for people with diabetes. However, illness or fever from vaccination can raise blood sugar. Monitor your blood sugar more closely after vaccination and consult your doctor if it is not well controlled. Annual flu shots are recommended for people with diabetes.
📦 Storage Guide
✅ DO
Store unused cartridges in the refrigerator between 2°C and 8°C.
❌ DON'T
Do not freeze the cartridges.
✅ DO
Keep the cartridge in its original packaging.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Once in use, keep at room temperature below 30°C for up to 28 days.
❌ DON'T
Do not expose to direct sunlight or heat.
✅ DO
Check the expiry date before use.
❌ DON'T
Do not use if the liquid is cloudy or has particles.
✈️ Traveling with This Medicine
When traveling, carry your insulin cartridges in their original packaging with a copy of your prescription. Keep them in a cool bag or refrigerator if possible, but never freeze them. For air travel, carry insulin in your hand luggage, as checked baggage may freeze. Adjust your injection times if crossing time zones, and consult your doctor for a plan. Carry extra supplies, including needles and a glucose source. Inform security staff that you are carrying medical supplies.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts to lower blood sugar within 1 to 2 hours after injection, peaks in 4 to 12 hours, and lasts about 12 to 18 hours.
A: No, this medicine is for subcutaneous injection only. It should not be injected into a muscle or vein.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Illness can raise blood sugar. You may need more insulin. Check your blood sugar more often and consult your doctor for advice.
🤔 Common Patient Concerns
🔄 Substitutes for insulatard 100iu/ml flexpen
View AllAlternative brands with exact same active ingredient:
-
huminsulin n 100iu/ml cartridgeEli Lilly and Company India Pvt Ltd ₹389.00 37.9% CHEAPER
-
insulatard hm 100iu/ml penfillNovo Nordisk India Pvt Ltd ₹425.00 32.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Insulin is addictive.
Fact: Insulin is a natural hormone that your body needs. It is not addictive. People with diabetes need it to survive. - Myth: Insulin causes blindness or kidney failure.
Fact: Poorly controlled diabetes causes these complications, not insulin. Insulin helps prevent them by controlling blood sugar. - Myth: You can stop insulin once your blood sugar is normal.
Fact: Blood sugar is normal because of insulin. Stopping it without medical advice can cause dangerous high blood sugar. - Myth: Insulin injections are very painful.
Fact: Most people find insulin injections only mildly uncomfortable. Using a new needle and rotating sites reduces pain.
🔄 Alternative Options
Generic Alternatives
- Insulin isophane (NPH) 100 IU/ml cartridge
Brand Alternatives
- Huminsulin N 100IU/ml Cartridge