Axirab A Capsule SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual tiredness or weakness
If experiencing severe symptoms, call emergency services immediately.
What is instaflex ar 200mg/20mg capsule sr used for?
This medicine is a combination of Aceclofenac (an NSAID) and Rabeprazole (a proton pump inhibitor) used to relieve pain and inflammation in conditions like arthritis while protecting the stomach from acid-related damage. It is taken orally with food, usually once or twice daily, as prescribed by a doctor.
- Generic Name: Aceclofenac (200mg) + Rabeprazole (20mg)
- Manufacturer: Innovcare Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 instaflex ar 200mg/20mg capsule sr के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक और रेबेप्राजोल का संयोजन है, जिसका उपयोग गठिया, जोड़ों के दर्द, सूजन और अकड़न को कम करने के लिए किया जाता है। एसिटोक्लोफेनाक दर्द और सूजन को कम करता है, जबकि रेबेप्राजोल पेट में एसिड को कम करके पेट की परत की रक्षा करता है। यह दवा आमतौर पर खाने के साथ ली जाती है और डॉक्टर की सलाह के अनुसार ही लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, दस्त, कब्ज, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति, गंभीर एलर्जी प्रतिक्रिया और हृदय संबंधी घटनाएं शामिल हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। कैप्सूल को पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन के साथ या भोजन के तुरंत बाद लें ताकि पेट की जलन कम हो। शराब और धूम्रपान से बचें। यदि आपको हृदय, गुर्दे या यकृत की समस्या है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 instaflex ar 200mg/20mg capsule sr Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, reduces joint inflammation" class="semantic-link" title="Medicines for swelling">swelling, and improves mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps control pain and inflammation in rheumatoid arthritis as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Reduces pain and stiffness in the spine and improves physical function.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Provides short-term relief for acute injuries, sprains, and strains.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-surgical pain and inflammation.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Dysmenorrhea","description":"Sometimes prescribed off-label for menstrual cramps due to its anti-inflammatory and analgesic properties.","evidence":"Limited"},{"condition":"Migraine","description":"Occasionally used off-label for acute migraine attacks, though not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Aceclofenac (200mg) + Rabeprazole (20mg) |
| Brand Name | instaflex ar 200mg/20mg capsule sr |
| Manufacturer | Innovcare Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, leading to decreased production of prostaglandins, which are mediators of pain, inflammation, and fever. Rabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in gastric parietal cells, thereby suppressing gastric acid secretion and protecting the stomach lining from NSAID-induced damage.
Mechanism Steps
💡 How to Take instaflex ar 200mg/20mg capsule sr
Strength: Sustained-release capsule containing Aceclofenac 200 mg and Rabeprazole 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once or twice daily, preferably with meals. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to therapy. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use with caution and monitor kidney and liver function regularly. Dose adjustment may be necessary. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction or alternative therapy may be required. Not recommended in severe kidney impairment (eGFR <30 mL/min). |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Avoid in severe liver impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule twice daily, but this must be confirmed by your doctor. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of instaflex ar 200mg/20mg capsule sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Clopidogrel | Moderate | |
| Ketoconazole | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Lithium
- ACE inhibitors / ARBs
- Diuretics
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Clopidogrel
- Ketoconazole / Itraconazole
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both Aceclofenac and alcohol can irritate the stomach lining and increase the risk of gastrointestinal bleeding, ulcers, and liver damage. Alcohol may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Aceclofenac, Rabeprazole, or any NSAID","Active peptic ulcer or history of recurrent peptic ulcers","Severe heart failure","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["Take with food to minimize stomach upset.","Avoid alcohol and smoking.","Do not drive or operate machinery if you feel dizzy.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of heart disease, kidney disease, liver disease, or high blood pressure.","Do not use for longer than prescribed without medical supervision.","Report any signs of bleeding, such as black stools or easy bruising.","Rabeprazole may increase the risk of bone fractures with long-term use.","May mask symptoms of infection."]
🤱 Lactation Safety
Aceclofenac and Rabeprazole may pass into breast milk. It is not known if they are safe during breastfeeding. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe abdominal pain, nausea, vomiting, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if overdose is recent. Monitor vital signs and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Swallow the capsule whole with a glass of water; do not crush, chew, or break it. Take it with food or immediately after a meal to reduce stomach upset. Do not take more than the recommended dose or for longer than prescribed without medical advice. Avoid alcohol and smoking while on this medicine, as they can increase the risk of stomach bleeding. Inform your doctor if you have a history of heart disease, kidney or liver problems, high blood pressure, or asthma. Do not use this medicine if you are allergic to Aceclofenac, Rabeprazole, or any other NSAID. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Regular monitoring of kidney and liver function may be required during long-term therapy. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and monitor kidney and liver function regularly. Dose adjustment may be necessary.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs like Aceclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Rabeprazole should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but it can increase the risk of bleeding and kidney problems. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures. Your dentist may advise temporary discontinuation or additional precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid high-impact exercises that may worsen joint pain. Consult your doctor or physiotherapist before starting any new exercise regimen. If you experience dizziness, avoid activities that require balance.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Most people can continue their normal activities, but listen to your body and rest when needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine abruptly without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor will advise whether to stop or adjust the dose based on your condition and response to therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal ulcers, bleeding, kidney impairment, liver injury, and cardiovascular events. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. The need for continued therapy should be reassessed periodically by your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedReduces stress on weight-bearing joints and improves symptoms.
Evidence: Well-establishedMay help with pain relief in some patients.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, adjust your dosing schedule gradually to avoid missing doses. Keep enough supply for your entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the medicine, but maximum anti-inflammatory effects may take a few days to a week.
A: No, it should be taken with food or immediately after a meal to reduce stomach upset and protect the stomach lining.
A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for instaflex ar 200mg/20mg capsule sr
View AllAlternative brands with exact same active ingredient:
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senrab ac 200mg/20mg capsule srSenen Biotech ₹50.63 58.1% CHEAPER
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dc rab-sr plus capsuleOrion Lifesciences ₹62.58 48.3% CHEAPER
-
aciril r 200mg/20mg capsuleMerril Pharma Pvt Ltd ₹65.00 46.3% CHEAPER
-
Rabidix A 200mg/20mg Capsule SRCaddix Healthcare ₹65.63 45.7% CHEAPER
-
dolostat r 200mg/20mg capsuleBlue Cross Laboratories Ltd ₹66.56 45% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach upset and protect the stomach lining. - Myth: This medicine is safe for long-term use without monitoring.
Fact: Long-term use requires regular monitoring of kidney and liver function and may increase the risk of ulcers and cardiovascular events. - Myth: This medicine can be taken with alcohol.
Fact: Alcohol increases the risk of gastrointestinal bleeding and should be avoided.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac + Rabeprazole generic capsules
Brand Alternatives
- Axirab A
- Aceclo-R
- Rab-Ace