Listril 5 Tablet (Lisinopril 5mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Decreased urine output or swelling in the legs
- Irregular heartbeat or muscle weakness
- Severe abdominal pain with nausea and vomiting
- Yellowing of the skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is inras 5mg tablet used for?
This medicine is a prescription ACE inhibitor used to treat high blood pressure, heart failure, and to improve survival after a heart attack. It works by relaxing blood vessels and reducing the workload on the heart.
- Generic Name: Lisinopril (5mg)
- Manufacturer: Wockhardt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 inras 5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लिसिनोप्रिल 5 मिलीग्राम की एक प्रिस्क्रिप्शन टैबलेट है, जिसका उपयोग उच्च रक्तचाप (हाई ब्लड प्रेशर), हृदय की विफलता (हार्ट फेल्योर), और दिल के दौरे के बाद जीवित रहने की दर को बेहतर बनाने के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर और दिल पर दबाव कम करके काम करती है। यह दवा गुर्दे की रक्षा भी करती है, खासकर मधुमेह वाले लोगों में। इसे रोज एक बार, भोजन के साथ या बिना, एक ही समय पर लेना चाहिए। इसे गर्भवती महिलाओं, जिन्हें एसीई इनहिबिटर से एलर्जी हुई हो, या जिन्हें गुर्दे की धमनी में रुकावट हो, उन्हें नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सूखी खांसी, चक्कर आना, सिरदर्द, थकान, और जी मिचलाना शामिल हैं। कुछ लोगों में चेहरे, होंठ, जीभ या गले में सूजन (एंजियोएडेमा) हो सकती है, जो एक गंभीर एलर्जी प्रतिक्रिया है और तुरंत डॉक्टर से संपर्क करना चाहिए। अन्य गंभीर दुष्प्रभावों में गुर्दे की समस्या, पोटेशियम का बढ़ना, और बहुत कम रक्तचाप शामिल हैं। यदि आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के बताए अनुसार ही लें। इसे रोज एक ही समय पर लें। भोजन के साथ या बिना ले सकते हैं। नमक के विकल्प जिनमें पोटेशियम होता है, उनसे बचें। शराब न पिएं क्योंकि इससे चक्कर आ सकते हैं और रक्तचाप बहुत कम हो सकता है। यदि आप गर्भवती हैं या गर्भवती होने की योजना बना रही हैं, तो तुरंत डॉक्टर को बताएं। बिना डॉक्टर की सलाह के दवा बंद न करें। नियमित जांच कराते रहें ताकि डॉक्टर आपके रक्तचाप, गुर्दे की कार्यप्रणाली और पोटेशियम के स्तर की निगरानी कर सकें।
💊 inras 5mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults.
- It helps reduce the risk of strokes, heart attacks, and kidney problems.","evidence":"Well-established"},{"condition":"Heart failure","description":"This medicine is used to treat heart failure by reducing the workload on the heart and improving symptoms such as shortness of breath and fatigue.","evidence":"Well-established"},{"condition":"Acute myocardial infarction","description":"This medicine is used after a heart attack to improve survival and reduce the risk of further heart problems.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"This medicine is used to protect kidney function in people with diabetes and high blood pressure.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to help prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Proteinuria in non-diabetic kidney disease","description":"May be used to reduce protein in the urine in some kidney conditions, but this is not a primary approved use.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Heart failure, Acute myocardial infarction, Diabetic nephropathy
📋 Drug Information
| Generic Name(s) | Lisinopril (5mg) |
| Brand Name | inras 5mg tablet |
| Manufacturer | Wockhardt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin-converting enzyme (ACE) inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends ACE inhibitors like lisinopril as first-line treatment for hypertension in adults, especially those with diabetes or kidney disease. |
| ICMR Guideline | The Indian Council of Medical Research recommends ACE inhibitors as one of the preferred initial therapies for hypertension in India, particularly in patients with diabetes, heart failure, or kidney disease. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the angiotensin-converting enzyme (ACE). ACE is responsible for converting angiotensin I into angiotensin II, a powerful substance that narrows blood vessels and stimulates the release of aldosterone, which causes the body to retain salt and water. By blocking ACE, this medicine reduces the levels of angiotensin II, leading to relaxation and widening of blood vessels, lower blood pressure, and reduced workload on the heart. It also decreases aldosterone secretion, which helps the kidneys excrete more salt and water. Additionally, this medicine inhibits the breakdown of bradykinin, a substance that dilates blood vessels, which contributes to its blood pressure-lowering effect but may also cause side effects like dry cough and angioedema.
Mechanism Steps
💡 How to Take inras 5mg tablet
Strength: Lisinopril 5 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for high blood pressure is 10 mg once daily, but your doctor may start with 5 mg if you are also taking a diuretic or have other risk factors. The dose may be increased gradually up to 40 mg daily based on your blood pressure response. For heart failure, the starting dose is 2.5 to 5 mg once daily, increased gradually as tolerated. After a heart attack, the usual dose is 5 mg within 24 hours, then 5 mg after 24 hours, then 10 mg once daily for 6 weeks. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | The safety and effectiveness of this medicine in children under 6 years of age have not been established. For children 6 years and older, the dose is based on weight and blood pressure response. Consult a pediatrician for appropriate dosing. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure and kidney function closely. Dose adjustments may be needed based on renal function. |
| Renal Impairment | In patients with impaired kidney function, the dose of this medicine should be reduced. For patients with creatinine clearance less than 30 mL/min, the initial dose is usually 2.5 to 5 mg once daily. Regular monitoring of kidney function is essential. |
| Hepatic Impairment | No specific dose adjustment is required for patients with liver impairment, but caution is advised. Monitor for signs of liver problems. |
| Maximum Daily Dose | The maximum recommended daily dose is 40 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of inras 5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Potassium supplements | Major | |
| NSAIDs | Major | |
| Lithium | Major | |
| Sacubitril | Major | |
| Aliskiren | Major | |
| Diuretics | Moderate | |
| Other antihypertensives | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Antipsychotics | Moderate | |
| Allopurinol | Moderate |
🚨 Major Interactions
- Potassium supplements or potassium-sparing diuretics
- Sacubitril
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Lithium
- Aliskiren
⚡ Moderate Interactions
- Diuretics
- Other antihypertensives
- Tricyclic antidepressants
- Antipsychotics
- Allopurinol
🍷 Alcohol Interaction
Alcohol can increase the blood pressure-lowering effect of this medicine and may cause dizziness, lightheadedness, or fainting. It is best to avoid alcohol or limit its consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["History of angioedema related to ACE inhibitors","Hereditary or idiopathic angioedema","Pregnancy","Bilateral renal artery stenosis","Concomitant use with sacubitril within 36 hours","Hypersensitivity to lisinopril or any component of the formulation"]
⚠️ Warnings & Precautions
["Angioedema: Serious allergic reactions can occur. Seek immediate medical help if swelling of face, lips, tongue, or throat occurs.","Hypotension: May cause low blood pressure, especially in patients who are volume-depleted or on diuretics. Monitor blood pressure closely.","Hyperkalemia: May increase potassium levels. Avoid potassium supplements and salt substitutes unless directed by a doctor.","Renal impairment: May worsen kidney function. Dose adjustment may be needed.","Cough: A persistent dry cough may occur. If it becomes bothersome, consult your doctor.","Neutropenia/Agranulocytosis: Rare but serious. Monitor white blood cell count in high-risk patients.","Use in pregnancy: Can cause fetal harm. Discontinue as soon as pregnancy is detected."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine can cause severe low blood pressure, electrolyte imbalances, and kidney failure. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, vasopressors, and close monitoring of vital signs and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Try to take it at the same time each day to help you remember. You may take it with or without food. If you have diabetes, monitor your blood sugar closely, especially during the first few weeks of treatment, as this medicine can sometimes cause low blood sugar. Avoid using salt substitutes that contain potassium, as they can raise your potassium levels dangerously. Drink enough water to stay hydrated, but do not overdo it. Avoid alcohol, as it can increase dizziness and lower your blood pressure too much. If you become pregnant or plan to become pregnant, tell your doctor immediately, because this medicine can harm the unborn baby. Do not stop taking this medicine suddenly without your doctor's advice, even if you feel well. Keep all your follow-up appointments so your doctor can check your blood pressure, kidney function, and potassium levels. Inform any healthcare provider you see that you are taking this medicine, especially before surgery or dental procedures.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure, kidney function, and potassium levels closely. Falls due to dizziness are a concern; take precautions when standing up.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy and should be stopped as soon as pregnancy is detected. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to prevent low blood pressure during the procedure. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or affect blood pressure during dental procedures. Your dentist may take precautions to monitor your blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or lightheadedness, especially when you first start taking it or when the dose is increased. Avoid strenuous exercise or heavy lifting until you know how this medicine affects you. Stay hydrated during exercise, and get up slowly from sitting or lying positions.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once they adjust to the medicine. Inform your employer if your job involves operating machinery or working at heights.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like angioedema, severe hypotension, or kidney problems, seek immediate medical attention. Your doctor may adjust the dose or switch you to a different medicine if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing high blood pressure and heart failure. Regular monitoring of kidney function, potassium levels, and blood pressure is important. In some patients, long-term use may lead to a persistent dry cough or rare side effects like kidney impairment. Do not stop the medicine without consulting your doctor, as untreated high blood pressure can lead to serious complications.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
ARBs like losartan are alternatives for patients who cannot tolerate ACE inhibitors due to cough.
Evidence: Well-establishedMedicines like amlodipine can be used alone or in combination for blood pressure control.
Evidence: Well-establishedDiet, exercise, and weight loss can help lower blood pressure and complement medicine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust the timing of your dose gradually, but consult your doctor for specific advice. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1 hour, but the full effect may take 2-4 weeks. Continue taking it regularly as prescribed.
A: Yes, you can take this medicine with or without food. However, taking it at the same time each day helps maintain consistent levels.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.
A: No, this medicine is not safe during pregnancy. It can harm the unborn baby. If you are pregnant or planning to become pregnant, talk to your doctor about alternative treatments.
A: No, do not stop taking this medicine without your doctor's advice. High blood pressure often has no symptoms, and stopping can cause it to rise again, increasing the risk of complications.
🤔 Common Patient Concerns
🔄 Substitutes for inras 5mg tablet
View AllAlternative brands with exact same active ingredient:
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stayhappi lisinopril 5mg tabletSarvagunaushdhi Pvt Ltd ₹10.00 72.6% CHEAPER
-
davaindia lisinopril 5mg tabletDavaindia Generic Pharmacy ₹12.00 67.1% CHEAPER
-
lisitec 5mg tabletCipla Ltd ₹20.62 43.5% CHEAPER
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lisir 5mg tabletKopran Ltd ₹23.44 35.8% CHEAPER
-
k pril 5mg tabletMefro Pharmaceuticals Pvt Ltd ₹27.19 25.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping this medicine can cause your blood pressure to rise again, increasing the risk of heart attack and stroke. Continue as prescribed. - Myth: This medicine damages the kidneys.
Fact: This medicine actually protects the kidneys in many people, especially those with diabetes. Regular monitoring helps ensure safety. - Myth: A dry cough means you are allergic to this medicine.
Fact: A dry cough is a common side effect but not an allergy. However, if you experience swelling of the face or throat, that is a serious allergic reaction and requires immediate medical attention.
🔄 Alternative Options
Generic Alternatives
- Lisinopril 5 mg tablet
Brand Alternatives
- Listril 5 Tablet
- Zestril 5 mg Tablet
- Prinivil 5 mg Tablet