Norflokem 400mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or bloody diarrhea
- Pain, swelling, or difficulty moving a joint, especially the Achilles tendon
- Numbness, tingling, or weakness in the hands or feet
- Confusion, hallucinations, or seizures
- Rash, itching, or swelling of the face, lips, tongue, or throat
- Difficulty breathing or chest pain
- Yellowing of the skin or eyes
- Decreased urine output or blood in urine
If experiencing severe symptoms, call emergency services immediately.
What is inor 400mg tablet used for?
This medicine contains Norfloxacin 400 mg, a fluoroquinolone antibiotic used to treat bacterial urinary tract infections. It works by blocking bacterial DNA replication. It is taken orally twice daily, usually for 3 to 14 days depending on the infection. It is not recommended for children, pregnant women, or breastfeeding mothers.
- Generic Name: Norfloxacin (400mg)
- Manufacturer: Noel Pharma India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 inor 400mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नोरफ्लोक्सासिन 400 मिलीग्राम टैबलेट के रूप में उपलब्ध है और यह एक फ्लोरोक्विनोलोन एंटीबायोटिक है। इसका उपयोग मूत्र मार्ग के संक्रमण, प्रोस्टेट के संक्रमण और कुछ आंतों के संक्रमणों के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर काम करती है और वायरल संक्रमण जैसे सर्दी-जुकाम पर असरदार नहीं होती। इसे डॉक्टर के परामर्श के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में असहजता, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में टेंडन में दर्द या टूटना, हाथ-पैरों में झुनझुनी या सुन्नपन, दौरे, गंभीर एलर्जी और लगातार दस्त शामिल हो सकते हैं। अगर आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल डॉक्टर के परामर्श से ही लें और पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करने लगें। एंटासिड, आयरन, जिंक या कैल्शियम सप्लीमेंट के साथ इस दवा को न लें, क्योंकि इससे दवा का असर कम हो सकता है। दिनभर पर्याप्त पानी पिएं। शराब का सेवन न करें। धूप में जाने से बचें और सनस्क्रीन का इस्तेमाल करें। अगर आपको चक्कर आते हैं तो वाहन न चलाएं।
💊 inor 400mg tablet Uses & Benefits
[{"condition":"Uncomplicated urinary tract infection","description":"This medicine is used to treat acute uncomplicated cystitis caused by susceptible bacteria such as Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis.","evidence":"Well-established"},{"condition":"Complicated urinary tract infection","description":"It is used for complicated urinary tract infections when the causative organism is susceptible and other options are not suitable.","evidence":"Established"},{"condition":"Bacterial prostatitis","description":"This medicine is used in some cases of acute or chronic bacterial prostatitis caused by susceptible organisms.","evidence":"Established"},{"condition":"Gastrointestinal infections","description":"It is used in selected bacterial gastrointestinal infections, including some cases of traveler's diarrhea, when indicated by a clinician.","evidence":"Limited"}]
Off-label uses: [{"condition":"Gonorrhea","description":"Norfloxacin has been used in the past for uncomplicated gonorrhea, but resistance is now widespread and it is not a preferred treatment.","evidence":"Limited"},{"condition":"Spontaneous bacterial peritonitis prophylaxis","description":"Sometimes used in selected patients with cirrhosis, but other agents are generally preferred.","evidence":"Limited"}]
Primary treatment for: Urinary tract infections
Also treats: Bacterial prostatitis, Gastrointestinal infections, Complicated urinary tract infections
📋 Drug Information
| Generic Name(s) | Norfloxacin (400mg) |
| Brand Name | inor 400mg tablet |
| Manufacturer | Noel Pharma India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C. Keep it in a dry place, away from direct sunlight and moisture. Do not store it in the bathroom. Keep it out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the packaging before use. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting two type II topoisomerase enzymes in bacteria, namely DNA gyrase and topoisomerase IV. DNA gyrase is responsible for introducing negative supercoils into bacterial DNA, which is necessary for replication and transcription. Topoisomerase IV is involved in separating interlinked daughter DNA molecules after replication. By binding to these enzymes, norfloxacin stabilizes the enzyme-DNA complex and prevents the resealing of the DNA strand breaks, leading to inhibition of bacterial DNA replication and ultimately bacterial cell death.
Mechanism Steps
💡 How to Take inor 400mg tablet
Strength: This medicine is available as an immediate-release tablet containing 400 mg of norfloxacin.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 400 mg taken orally twice daily for most urinary tract infections. For uncomplicated cystitis, a shorter course of 3 to 7 days may be sufficient, while complicated infections may require 10 to 14 days. The dose and duration must be individualized by a qualified clinician based on the indication, severity of infection, age, weight, renal and hepatic function, and the susceptibility of the causative organism. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function, which can increase the levels of this medicine in the body. Dose adjustment may be necessary based on kidney function. Elderly patients are also at higher risk of tendon rupture, central nervous system effects, and other serious side effects. Use with caution and under close medical supervision. |
| Renal Impairment | In patients with reduced kidney function, the dose of this medicine may need to be adjusted. For patients with a creatinine clearance between 30 and 60 mL/min, a dose reduction may be considered. For patients with a creatinine clearance below 30 mL/min, the dose may need to be reduced further or the dosing interval extended. The exact dose must be determined by a qualified clinician based on the individual's kidney function. |
| Hepatic Impairment | No specific dose adjustment is established for patients with liver impairment. However, this medicine should be used with caution in patients with severe liver disease. Monitor liver function tests if symptoms of liver injury occur. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 800 mg (400 mg twice daily) for adults with normal kidney function. Do not exceed this dose unless specifically instructed by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of inor 400mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Sucralfate | Major | |
| Iron supplements | Major | |
| Zinc supplements | Major | |
| Warfarin | Major | |
| Theophylline | Major | |
| Caffeine | Moderate | |
| Nitrofurantoin | Moderate | |
| Probenecid | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Antacids containing magnesium or aluminum
- Sucralfate
- Iron supplements
- Zinc supplements
- Multivitamins containing iron or zinc
- Warfarin
- Theophylline
- Caffeine
- Nitrofurantoin
- Probenecid
⚡ Moderate Interactions
- Cyclosporine
- Oral hypoglycemics
- NSAIDs
- Corticosteroids
- QT-prolonging drugs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can worsen dizziness, drowsiness, and central nervous system side effects. It may also increase the risk of liver problems and can interfere with the body's ability to fight infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to norfloxacin or any other fluoroquinolone antibiotic","Children and adolescents below 18 years of age, except in specific approved situations","Pregnancy","Breastfeeding","History of tendon disorders associated with fluoroquinolone use","Myasthenia gravis"]
⚠️ Warnings & Precautions
["This medicine can cause tendon inflammation and rupture, especially in older adults, those with kidney disease, and those taking corticosteroids. Stop the medicine and seek medical attention if you experience tendon pain or swelling.","This medicine can cause peripheral neuropathy, which may be irreversible. Report numbness, tingling, or weakness in the hands or feet immediately.","This medicine can cause central nervous system effects, including seizures, confusion, and hallucinations. Use with caution in patients with a history of seizures or psychiatric disorders.","This medicine can cause severe allergic reactions, including anaphylaxis. Seek emergency medical help if you develop rash, swelling, or difficulty breathing.","This medicine can cause Clostridioides difficile-associated diarrhea, which may occur during or after treatment. Report severe or bloody diarrhea to your doctor.","This medicine can cause photosensitivity. Avoid excessive sun exposure and use sunscreen.","This medicine can worsen muscle weakness in patients with myasthenia gravis. Avoid use in these patients.","This medicine should be used with caution in patients with kidney or liver disease. Dose adjustment may be needed.","This medicine can increase the effects of caffeine and theophylline. Limit caffeine intake and monitor theophylline levels.","This medicine should not be used for viral infections such as the common cold or flu."]
🤱 Lactation Safety
Norfloxacin is excreted in breast milk. Because of the potential risk of serious adverse effects in nursing infants, including cartilage damage and tendon problems, this medicine is generally not recommended during breastfeeding. A doctor may advise either discontinuing the medicine or switching to a safer alternative.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhea, and central nervous system effects such as dizziness, confusion, or seizures. There is no specific antidote. Treatment is supportive and symptomatic. Maintain adequate hydration to prevent crystalluria. In case of overdose, contact a poison control center or seek emergency medical attention immediately.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine only when prescribed by a qualified clinician and complete the full course even if you start feeling better. Do not share this medicine with others or use leftover tablets for a future illness. Avoid taking antacids, sucralfate, iron supplements, zinc supplements, or multivitamins containing these minerals within two hours before or after taking this medicine, as they can reduce its absorption. Drink plenty of water throughout the day to keep your urine dilute and reduce the risk of crystal formation in the urine. Avoid excessive caffeine while taking this medicine because fluoroquinolones can increase caffeine effects. Do not drive or operate heavy machinery if you feel dizzy or confused. Inform your doctor if you have kidney problems, liver problems, diabetes, myasthenia gravis, or a history of tendon problems. Avoid sun exposure and use sunscreen because this medicine can make your skin more sensitive to sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, central nervous system effects, and kidney-related side effects from this medicine. Kidney function declines with age, so dose adjustment may be necessary. Elderly patients should be monitored closely for any signs of tendon pain, confusion, or falls. Adequate hydration is especially important in this age group.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are planning to become pregnant or are pregnant. Fluoroquinolones can affect fetal development, particularly cartilage formation. If you are planning pregnancy, discuss alternative antibiotics with your doctor. Use effective contraception while taking this medicine if you are of childbearing age.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents or affect wound healing. Your doctor may advise you to stop the medicine before surgery or adjust the dose based on your kidney function.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no major interactions with common dental anesthetics, but your dentist may need to adjust other medications. Maintain good oral hygiene and follow your dentist's advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it can increase the risk of tendon injury. If you experience joint or tendon pain, stop exercising and consult your doctor. Light activities like walking are generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or confusion in some people. Avoid driving or operating heavy machinery until you know how the medicine affects you. If your work involves operating machinery or requires high alertness, inform your employer and take necessary precautions. Most people can continue their normal daily activities while taking this medicine.
🛑 When to Stop This Medicine
Stop taking this medicine and seek immediate medical attention if you experience any serious side effects such as tendon pain or swelling, numbness or tingling in the hands or feet, severe diarrhea, allergic reactions, or seizures. Do not stop the medicine early just because you feel better, as this can lead to recurrence of the infection and antibiotic resistance. Always consult your doctor before stopping the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of antibiotic resistance, tendon problems, peripheral neuropathy, and central nervous system effects. It may also disrupt the normal balance of bacteria in the body, leading to secondary infections such as Clostridioides difficile-associated diarrhea. Regular monitoring of kidney and liver function may be needed if used for prolonged periods. This medicine should only be used for the prescribed duration and indication.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water helps flush out bacteria from the urinary tract and can complement antibiotic treatment.
Evidence: Well-establishedSome studies suggest cranberry products may help prevent urinary tract infections, but evidence for treatment is limited.
Evidence: LimitedProbiotics may help restore gut flora disrupted by antibiotics and reduce the risk of antibiotic-associated diarrhea.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, if you are due for any vaccinations, inform your doctor that you are taking this antibiotic. Live vaccines should generally be avoided while taking antibiotics, as the immune response may be affected.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue taking the medicine at evenly spaced intervals as prescribed. Check the laws of your destination country regarding carrying prescription antibiotics. Do not share this medicine with anyone else.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: It is best taken on an empty stomach, but if it upsets your stomach, you can take it with a small snack. Avoid dairy products and antacids within 2 hours of the medicine.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is best to avoid alcohol while taking this medicine, as it can worsen dizziness and other side effects.
A: This medicine is generally not recommended during pregnancy. Consult your doctor for safer alternatives.
🤔 Common Patient Concerns
🔄 Substitutes for inor 400mg tablet
View AllAlternative brands with exact same active ingredient:
-
norga 400mg tabletAgron Remedies Pvt Ltd ₹6.87 85.9% CHEAPER
-
enteroflox 400mg tabletDeys Medical ₹6.96 85.7% CHEAPER
-
norspan 400mg tabletBlue Cross Laboratories Ltd ₹8.74 82% CHEAPER
-
embenor 400mg tabletAbbott ₹9.55 80.3% CHEAPER
-
norbid 400mg tabletAlembic Pharmaceuticals Ltd ₹9.73 80% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Norfloxacin can cure the common cold.
Fact: Norfloxacin is an antibiotic that only works against bacteria. It is not effective against viruses such as the common cold or flu. - Myth: You can stop taking Norfloxacin once you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent the infection from returning and to reduce the risk of antibiotic resistance. - Myth: Norfloxacin is safe for children.
Fact: Norfloxacin is generally not recommended for children below 18 years of age because of the risk of cartilage and tendon damage. - Myth: Norfloxacin can be taken with milk or antacids.
Fact: Milk, antacids, and mineral supplements can reduce the absorption of Norfloxacin. They should be taken at least 2 hours apart.
🔄 Alternative Options
Generic Alternatives
- Norfloxacin 400 mg tablet
Brand Alternatives
- Norflokem 400mg tablet