anspas forte 500mg/450mg tablet
What is anspas forte 500mg/450mg tablet used for?
Abmef-DS Oral Suspension (Mefenamic Acid + Paracetamol) is used to treat PAIN ANALGESICS. It contains Mefenamic Acid (500mg) + Paracetamol (450mg), which Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin syn. Always consult your doctor before use. Take as prescribed.
- Generic Name: Mefenamic Acid + Paracetamol
- Manufacturer: Noel Pharma India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ anspas forte 500mg/450mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Mefenamic Acid + Paracetamol |
| Brand Name | Abmef-DS Oral Suspension |
| Manufacturer | Noel Pharma India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis; Paracetamol inhibits COX in the central nervous system and modulates pain perception.
Mechanism Steps
๐ก How to Take anspas forte 500mg/450mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of anspas forte 500mg/450mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Diarrhea
- Dizziness
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Thrombocytopenia
- Pancreatitis
- Aplastic anemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased GI ulceration risk |
| Alcohol | Major | Hepatotoxicity and GI bleeding |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Anticoagulants | Moderate | Increased bleeding risk |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of mefenamic acid |
| Cholestyramine | Minor | Reduced absorption of mefenamic acid |
| Oral contraceptives | Minor | Possible reduced contraceptive efficacy |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
- Alcohol
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (mefenamic acid).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy.
๐ Monitoring Parameters
Liver function, renal function, CBC, signs of GI bleeding.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for mefenamic acid.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.