Nanoxel 300mg Injection (Paclitaxel): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat during infusion
- Fever above 38°C or chills
- Unusual bleeding or bruising
- Severe chest pain or palpitations
- Severe abdominal pain or persistent vomiting
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is innotaxel 300mg injection used for?
This medicine is a chemotherapy injection containing paclitaxel, used to treat breast, ovarian, lung, and other cancers. It works by stopping cancer cell division and is given intravenously by a healthcare professional.
- Generic Name: Paclitaxel (300mg)
- Manufacturer: Innova Formulations Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 innotaxel 300mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा पैक्लिटैक्सेल 300 मिलीग्राम इंजेक्शन है, जिसका उपयोग कैंसर के इलाज के लिए किया जाता है। यह स्तन कैंसर, डिम्बग्रंथि कैंसर, फेफड़ों के कैंसर और एड्स से संबंधित कपोसी सारकोमा के इलाज में प्रभावी है। यह दवा कैंसर कोशिकाओं के विभाजन को रोककर उन्हें नष्ट करती है। यह केवल अस्पताल या कैंसर केंद्र में डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है। इसे स्वयं नहीं लगाया जा सकता।
साइड इफेक्ट्स: आम दुष्प्रभावों में बालों का झड़ना, मतली, उल्टी, दस्त, मुंह के छाले, जोड़ों और मांसपेशियों में दर्द, और हाथ-पैरों में सुन्नपन शामिल हैं। गंभीर दुष्प्रभावों में तेज एलर्जी, संक्रमण का खतरा, रक्तस्राव, और हृदय की धड़कन में गड़बड़ी हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। एलर्जी के लक्षण जैसे दाने, खुजली, सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर को बताएं। संक्रमण से बचें क्योंकि यह दवा प्रतिरक्षा प्रणाली को कमजोर कर सकती है। गर्भावस्था के दौरान इस दवा का उपयोग न करें। टीके लगवाने से पहले डॉक्टर से सलाह लें।
💊 innotaxel 300mg injection Uses & Benefits
[{"condition":"Breast cancer","description":"Used as part of combination chemotherapy for node-positive breast cancer after standard treatment, or as monotherapy for metastatic disease.","evidence":"Well-established"},{"condition":"Ovarian cancer","description":"Used as first-line therapy in combination with platinum-based agents for advanced ovarian carcinoma.","evidence":"Well-established"},{"condition":"Non-small cell lung cancer","description":"Used in combination with other chemotherapy drugs for advanced or metastatic non-small cell lung cancer.","evidence":"Well-established"},{"condition":"AIDS-related Kaposi's sarcoma","description":"Used as second-line therapy for advanced AIDS-related Kaposi's sarcoma.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gastric cancer","description":"Sometimes used in combination regimens for advanced gastric cancer.","evidence":"Limited"},{"condition":"Head and neck cancer","description":"Occasionally used in combination therapy for recurrent or metastatic head and neck cancers.","evidence":"Limited"},{"condition":"Bladder cancer","description":"Investigated as part of combination therapy for advanced bladder cancer.","evidence":"Limited"}]
Primary treatment for: Cancer (breast, ovarian, lung, Kaposi's sarcoma)
Also treats: Metastatic breast cancer, Advanced ovarian cancer, Non-small cell lung cancer, AIDS-related Kaposi's sarcoma
📋 Drug Information
| Generic Name(s) | Paclitaxel (300mg) |
| Brand Name | innotaxel 300mg injection |
| Manufacturer | Innova Formulations Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimicrotubule agents- Taxanes |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store in a refrigerator at 2°C to 8°C. Do not freeze. Protect from light. Keep in the original carton until use. |
| Shelf Life | Refer to the product label for the exact shelf life. Typically 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to the beta-tubulin subunit of microtubules, which are essential structures for cell division. This binding stabilises the microtubules and prevents their normal disassembly, leading to cell cycle arrest in the G2/M phase and eventually cell death. Cancer cells are particularly sensitive to this effect because they divide rapidly.
Mechanism Steps
💡 How to Take innotaxel 300mg injection
Strength: Injection: 300 mg per vial
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the type of cancer, stage, prior treatments, and patient factors such as body surface area, liver function, and blood counts. Common regimens include 175 mg/m² given as a 3-hour infusion every 3 weeks, or 135 mg/m² every 3 weeks in combination with other agents. Dose adjustments are required for liver impairment, low blood counts, or severe side effects. This medicine must only be administered by a healthcare professional. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects such as peripheral neuropathy and bone marrow suppression. Dose adjustments may be necessary based on overall health and organ function. |
| Renal Impairment | No specific dose adjustment is recommended for renal impairment, but caution is advised in patients with severe renal impairment. |
| Hepatic Impairment | Dose reduction is recommended for patients with moderate to severe hepatic impairment. Monitor liver function closely. |
| Maximum Daily Dose | The maximum dose depends on the regimen and indication. It is determined by the treating oncologist. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of innotaxel 300mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Gemfibrozil | Major | |
| Warfarin | Moderate | |
| Doxorubicin | Moderate | |
| Live vaccines | Major |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP2C8 inhibitors (e.g., gemfibrozil)
- Live vaccines
⚡ Moderate Interactions
- Warfarin
- Doxorubicin
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and worsen side effects such as nausea and dizziness. It is best to avoid alcohol during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe hypersensitivity to paclitaxel or other taxanes","Severe liver impairment","Baseline neutrophil count less than 1500 cells/mm³","Pregnancy","Breastfeeding"]
⚠️ Warnings & Precautions
["This medicine should be administered under the supervision of a qualified oncologist.","Premedication with corticosteroids, antihistamines, and H2 antagonists is required to prevent allergic reactions.","Blood counts should be monitored frequently.","Patients should be monitored for signs of infection.","Avoid live vaccines during treatment.","Use effective contraception during and after treatment."]
🤱 Lactation Safety
It is not known whether paclitaxel is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding should be discontinued during treatment and for at least 2 weeks after the last dose.
💊 Overdose Management
Overdose may cause severe bone marrow suppression, peripheral neuropathy, and mucositis. There is no specific antidote. Treatment is supportive and symptomatic. Patients should be monitored closely and given appropriate supportive care.
⏰ Missed Dose
This medicine is given by a healthcare professional in a clinical setting. If you miss an appointment for your infusion, contact your doctor or clinic as soon as possible to reschedule. Do not attempt to self-administer.
Additional Safety Advice
This medicine must only be given by a qualified healthcare professional in a setting equipped to manage allergic reactions. Inform your doctor immediately if you experience any signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing during or after the infusion. Avoid contact with people who have infections, as this medicine can lower your immunity. Use effective contraception during treatment and for some time after, as this medicine can harm an unborn baby. Do not receive live vaccines while on this medicine. Report any unusual bleeding, bruising, fever, or persistent vomiting to your doctor without delay.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as peripheral neuropathy, bone marrow suppression, and cardiac effects. Dose adjustments and close monitoring are recommended.
🤰 Pregnancy Planning (TTC)
This medicine can harm an unborn baby. Women of childbearing potential should use effective contraception during treatment and for at least 6 months after the last dose. Men should also use contraception for at least 3 months after treatment. Discuss pregnancy planning with your doctor before starting treatment.
🏥 Post-Surgery Considerations
This medicine may affect wound healing due to its effects on cell division. Inform your surgeon if you are receiving this medicine before any surgery. Your doctor may recommend delaying surgery until blood counts recover.
🦷 Dental Procedures
This medicine can increase the risk of bleeding and infection. Inform your dentist that you are receiving this medicine before any dental procedure. Your dentist may recommend postponing non-urgent procedures until your blood counts recover.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Light exercise such as walking may help reduce fatigue, but avoid strenuous activities if you have low blood counts or feel unwell. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You may need to take time off work during treatment cycles. Fatigue, nausea, and neuropathy can affect your ability to work. Discuss your treatment schedule with your employer and plan for flexibility.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your oncologist. Treatment may be stopped or adjusted if severe side effects occur, such as severe neuropathy, low blood counts, or allergic reactions. Your doctor will decide the appropriate course.
📅 Long-Term Use Effects
Long-term use may cause persistent peripheral neuropathy, which can affect daily activities. Regular monitoring of blood counts, liver function, and neurological status is essential. Some patients may experience lasting fatigue or hair loss that resolves after treatment ends.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the cancer type, other drugs like docetaxel or platinum agents may be used.
Evidence: Well-establishedFor some cancers, targeted therapies may be more appropriate.
Evidence: Well-establishedMay be used for certain cancers, either alone or in combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment with this medicine due to the risk of infection. Inactivated vaccines may be given, but their effectiveness may be reduced. Consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in the original carton to protect from light
❌ DON'T
Do not remove from carton until use
✅ DO
Keep out of reach of children
❌ DON'T
Do not use if the solution is discoloured or contains particles
✈️ Traveling with This Medicine
This medicine is administered in a hospital or clinic, so travel is not typically required for administration. If you need to travel for treatment, carry your prescription and medical records. Store the medicine in a refrigerator at 2°C to 8°C during travel. Check customs regulations for carrying injectable medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects on cancer cells begin immediately, but clinical response may take weeks to months. Your doctor will monitor your progress with regular scans and tests.
A: It is not recommended to drive immediately after the infusion due to potential dizziness and fatigue. Arrange for someone to drive you home.
A: Avoid alcohol, grapefruit, live vaccines, and contact with people who have infections. Use effective contraception.
🤔 Common Patient Concerns
🔄 Substitutes for innotaxel 300mg injection
View AllAlternative brands with exact same active ingredient:
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Taxeleon 300mg InjectionNeon Laboratories Ltd ₹1,677.50 83.4% CHEAPER
-
celtax 300mg injectionCelon Laboratories Ltd ₹9,495.23 6.2% CHEAPER
-
zupaxel 300mg injectionZuventus Healthcare Ltd ₹10,279.80 1.5% COSTLIER
-
altaxel nova 300mg injectionAlkem Laboratories Ltd ₹10,584.26 4.5% COSTLIER
-
paclitax 300mg injectionCipla Ltd ₹10,764.60 6.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home.
Fact: This medicine must be given by a healthcare professional in a clinical setting. - Myth: This medicine has no side effects.
Fact: This medicine can cause significant side effects, including hair loss, low blood counts, and nerve damage. - Myth: This medicine can cure all cancers.
Fact: This medicine is effective for specific types of cancer and is used as part of a comprehensive treatment plan.
🔄 Alternative Options
Generic Alternatives
- Paclitaxel injection
Brand Alternatives
- Nanoxel 300mg injection